<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Nzeyimana (2010)
Title Monitoring of HIV-1 drug resistance and associated programmatic factors in patients initiating antiretroviral therapy at two ART sites in Bujumbura, Burundi.
Citation IWHHVDR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 244
NumPts 244
Subtype C, A, D, H, C + D, G, CRF45_cpx

 
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Page 1   listing Isolate 1 to Isolate 100 from Total 244 Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
102_1002 102_1002 None None   K11E, V35T, E40D, E44D, K49R, V60I, V118VI, D121H, K122E, D123S, I135T, T139AV, K173S, Q174K, D177E, V179I, T200A, Q207A, R211RK, F214L, V245Q, A272S, K277R, L283I, V292I, I293V, V317A, S322A, G335D, K347KR, R356K, G359T, T377M, K390R, A400AT, E404D  
102_1011 102_1011 None None   V21I, V35T, T39Q, V60I, K102Q, A158AS, K173T, Q174K, D177E, I178M, G196E, T200A, Q207E, R211K, V245Q, E248D, D250E, S251D, A272P, K281R, E291D, V292I, I293V, E297A, D324E, I329V, Q334L, G335D, R356K, M357R, G359T, A371V, I375V, K390R, K395R, A400T, T403A, E404D  
102_1017 102_1017 None None   V35T, E36A, T39E, E40D, S48T, V60I, K122E, D123S, I142V, A158S, K173A, D177E, T200A, Q207A, R211K, V245Q, A272P, K277R, T286A, V292I, I293V, P294T, K311R, Q334N, G335D, R356K, G359T, T377Q, K390R, E404D, K431T  
102_1018 102_1018 None None   K22R, V35T, E36A, T39D, S48T, E53D, V60I, K122E, D123S, I135T, Q174H, D177E, T200A, Q207K, R211K, F214L, V245Q, A272P, T286A, E291D, V292I, G335D, G359T, K366R, T377Q, K390R, E404D N54NI 
102_1020 102_1020 None None   P4T, V35T, E36A, T39E, E40D, K122E, D123S, T139M, S162Y, K173E, D177E, T200A, Q207E, R211K, K223KR, V245M, D250E, A272P, K277R, E291D, I293V, Q334H, G335D, R356K, G359T, T377MV, K390R, A400T, E404D  
102_1024 102_1024 None None   V35T, E36A, T39E, K43Q, K122E, D123DN, I142V, A158S, K173T, Q174K, D177E, I178M, G196GE, T200A, Q207E, V245Q, A272P, K277KR, T286A, E291D, V292I, I293V, K311KR, Q334N, G335D, R356K, M357R, G359T, T377Q, K390R, E404D, K431T  
102_1026 102_1026 None None   V35T, E36A, T39D, S48T, V60I, K122E, I135V, K173A, Q174R, D177E, I178M, T200A, Q207E, R211K, V245Q, A272P, E291D, V292I, I293V, K311R, Q334N, G335D, R356K, M357R, G359T, A371AV, T377M, K390R, A400IT, E404D  
102_1027 102_1027 None None   V35T, E36A, T39E, E40ED, K43R, S48E, D123E, I142IT, K173V, Q174QKR, D177E, I178IL, T200A, Q207E, R211RK, F214L, V245Q, A272P, K277R, T286TA, E291D, V292I, I293V, G335D, R356K, G359HN, V365I, K366R, T377I, K390R, E404D Q85Q* 
102_1033 102_1033 None None   V8VI, V35T, E36A, T39E, E40D, E53ED, K122P, D123S, A158S, K166R, K173T, D177E, T200A, Q207E, R211K, V245H, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E297A, G335D, R356K, M357R, G359T, T377M, V381I, K390R, E404D  
102_1037 102_1037 None None   V35T, E36A, T39E, E40D, K43R, K122E, D123GS, A158S, K173A, D177E, Q207E, V245Q, A272P, T286A, E291D, V292I, I293V, G335D, R356K, M357R, G359T, T377L, K390R, E404D, V417I  
102_1039 102_1039 None None   E6K, K11A, V35T, T39N, K49KQ, V118I, K122E, D123N, E138A, I142V, S162C, K173A, D177E, I178L, T200E, E204K, Q207A, R211K, F214L, V245Q, A272P, T286A, V292I, I293V, P294T, E312DN, I326V, G335D, F346L, M357K, G359S, K366R, A371V, I375V, T377LQ, K388R, K390R, A400T, E404D  
102_1046 102_1046 None None   K22R, V35T, E36A, T39E, I47IL, S48T, K122E, D123N, T139A, A158S, K173A, Q174K, D177E, T200A, Q207E, V245Q, A272P, L283I, T286V, V292I, I293V, Q334H, G335D, R356K, M357R, G359T, T377Q, S379C, K390R, E404D  
102_1047 102_1047 None None   V35T, E40D, K49R, K122E, D123N, I135T, K173A, Q174K, D177E, V179I, Q207A, R211S, V245Q, T286A, E291D, I293V, P294T, K311R, E312D, S322A, G335D, M357K, G359S, K366R, T369A, A371V, I375V, A376V, T377M, T386A, A400T, T403M, E404D  
102_1066 102_1066 None None   V35T, T39M, V60I, D123S, I135T, K173LS, D177E, V179I, T200A, Q207A, R211S, V245C, K281R, T286A, E291D, I293V, P294T, V317VA, G335D, M357K, G359S, K366R, T369A, A371V, I375V, A376V, T377M, A400T, T403M, E404D  
102_1074 102_1074 None None   E6D, V35T, T39E, S48T, K122E, D123DE, K173A, T200A, Q207K, V245Q, E248N, D250E, A272P, K277R, L283I, T286A, E291D, V292I, I293V, E297A, A304E, I329V, G335D, F346L, R356K, M357Q, G359A, T369A, T377K, S379C, K390R, T403TI, E404D  
102_1076 102_1076 None None   K20R, V35T, E36A, T39E, E40ED, K122E, D123N, K173A, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, P294PT, K311KR, D324E, I326K, Q334N, G335D, R356K, M357Q, G359T, T377L, K388I, K390R, A400T, E404D, V435A  
102_1083 102_1083 None None   I5IV, V35T, K49R, K122E, D123NS, I135T, K173S, D177E, V179I, T200A, Q207A, R211S, V245Q, K281R, E291D, I293V, P294T, E312D, G335D, R356K, M357K, G359S, K366R, T369A, A371V, I375V, A376V, T377M, A400T, T403M, E404D, E432D  
102_1084 102_1084 None None   V35T, E36A, T39E, I47L, S48T, V60I, K122E, D123GS, I135V, N175NY, D177E, T200A, Q207E, R211K, V245Q, L260I, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, T377Q, K390R, E404D  
102_1095 102_1095 None None   E28D, V35T, E36A, T39E, E40D, K122E, D123G, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, Q278N, L283LI, T286V, E291D, V292I, I293V, P294PALV, G335D, R356K, M357R, G359T, I375V, T377LQ, S379C, K390R, E404D  
102_1103 102_1103 None None   K11T, T27S, V35T, K104R, K122E, D123NS, K173S, Q174K, D177E, I178IM, V179I, Q207A, V245M, E248D, L283I, I293V, P294T, E312D, R356K, M357K, R358K, G359A, A371V, I375V, A376V, T377M, A400T, E404D  
102_1105 102_1105 None None   V35T, E36A, T39E, E40D, K49R, K122E, D123G, A158S, S162D, K173T, D177E, T200A, Q207N, R211K, V245Q, A272P, K277R, V292I, I293V, G335D, R356K, M357R, G359T, T377Q, K390R, T403V, E404D  
102_1106 102_1106 None None   P4S, V35T, E36EA, T39E, K43R, S48T, T69S, K122E, D123S, A158S, K173A, D177E, I178V, T200AE, Q207E, R211RK, V245Q, D250E, S251D, A272P, K277R, T286A, E291D, V292I, I293V, E297A, G335D, R356K, G359T, T377M, K390R, A400T, E404D  
102_1109 102_1109 None None   V35T, E36A, T39E, S48T, D123S, K173A, Q174K, D177EG, T200A, Q207E, R211K, V245Q, E248D, D250E, A272P, K277R, K281R, T286A, E291D, V292I, I293V, Q334N, G335D, R356K, G359T, A376S, T377Q, K390R, A400S, E404D  
102_1111 102_1111 None None   E6ED, V35T, E36A, T39E, E40D, K49R, K122E, D123N, I142IV, A158S, T165I, K173T, Q174QK, D177E, I178M, T200A, Q207E, V245Q, A272P, E291D, V292I, I293IV, Q334H, G335D, R356K, G359T, K366R, T377Q, K390R, E404D  
102_1114 102_1114 None None   V35T, E36A, T39E, S48T, V60VI, K122E, D123S, I135T, Q145C, K173T, Q174K, D177E, T200A, I202V, Q207K, F214FL, V245Q, A272P, K277KR, T286A, E291D, V292I, I293V, V317VA, I329L, Q334H, G335D, R356K, G359T, T377L, K390R, A400T, E404D  
102_1115 102_1115 None None   E6K, V35T, E36A, T39E, S48T, K122E, A158S, K173A, Q174K, D177E, T200A, Q207K, R211M, V245H, D250E, S251SC, A272P, K277R, T286A, E291D, V292I, I293V, V317VA, I326V, Q334N, G335D, R356K, G359T, T377L, K390R, E404D, E413D  
102_1117 102_1117 None None   V35T, E36A, T39E, S48T, D121H, K122E, I142V, A158S, K173T, T200A, Q207E, V245E, D250E, A272S, T286A, E291D, V292I, I293V, G335D, R356K, R358K, G359N, T377M, T386I, K390R, I393M, A400T, E404D, V417I, P421PL, E430K  
102_1118 102_1118 None None   K32R, V35T, E40D, S48SA, K49R, I50V, E53D, V60I, K122E, D123S, A158S, K173A, D177E, V179I, Q207AT, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E297K, R356K, G359T, T377Q, K390R, E404D  
102_1120 102_1120 None None   V35T, E36A, T39E, S48T, K122E, D123G, A158S, K166R, K173A, D177E, I178M, T200A, Q207D, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, L295M, E297A, S322A, D324E, G335D, E344D, R356K, M357R, G359T, T377L, K390KR, E404D  
102_1121 102_1121 None None   V35I, V60I, K122E, D123G, I135T, I142V, K173S, Q174K, D177E, V179I, G196E, T200A, Q207A, R211S, V245Q, E248D, S251T, K281R, E291D, I293V, P294AT, K311R, E312D, G335D, R356RK, M357K, G359S, I375V, T386I, K390R, A400T, T403M, E404D  
102_1124 102_1124 None None   K20R, V35T, T39E, V60I, K64KR, D121H, I135T, T165TI, K173A, Q174K, D177E, G196E, Q207A, R211S, V245Q, A272Q, T286A, E291D, V292I, I293V, V317A, G335D, R356K, M357R, G359T, K366R, T377M, K390R, E404D, E432D  
102_1125 102_1125 None None D67DH  V35T, E36A, T39E, S48T, K122E, D123N, A158S, K166R, K173T, D177E, T200A, Q207QHKN, R211K, V245Q, D250E, D256DE, A272P, K281R, E291D, V292I, I293V, V317A, I326V, Q334D, R356K, G359T, T377M, K390R, E404D  
102_1127 102_1127 None None  K103N V35M, E36A, T39E, S48E, K122KE, K173A, Q174K, D177E, T200A, Q207E, R211RK, V245Q, E248N, D250E, S251C, A272P, K277R, T286A, E291D, V292I, I293V, G335D, R356K, G359S, T377M, S379C, I380IV, K390KR, E396D, A400T, E404D  
102_1129 102_1129 None None   V35T, E36A, T39E, E40D, S48T, V60I, K122KE, A158S, K173AT, Q174QK, D177E, T200A, Q207G, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, K311KR, V317VA, Q334H, G335D, R356K, G359T, T377Q, K390R, A400T, E404D  
102_1134 102_1134 None None   V35T, T39L, V60I, K102Q, I142V, D177E, I178M, V179I, T200R, E204D, Q207E, R211KT, V245Q, T286A, E291D, V292I, I293V, K311R, D324E, G333E, Q334QP, M357K, G359S, K366R, T369V, A371V, I375V, A376T, T377M, K390R, A400T, E404D, E432D S191SF 
102_1137 102_1137 None None   V21I, V35I, E40ED, V60I, D121Y, K122E, K166KR, E194D, G196E, Q197R, T200IR, Q207E, R211K, V245E, D250E, A272P, K275R, K277R, L282C, L283I, I293V, G335D, P345Q, F346Y, R356K, M357V, A360T, E370A, T377Q, S379C, K390R, A400T, E404D  
102_1139 102_1139 None None   V8I, K20R, V35T, E40D, K49R, V60I, K122E, D177E, E194EG, T200A, Q207N, V245LMPT, A272P, K277KR, T286A, E291D, V292I, I293V, P294T, E297EA, G335D, R356K, M357V, G359T, A376AS, T377M, S379C, K390R, A400T, E404D  
102_1141 102_1141 None None   V35T, E36A, T39E, E40D, S48T, T139A, I142V, K173T, D177E, T200AV, Q207A, R211K, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294PS, Q334H, G335D, R356K, G359T, T377Q, K390R, A400T, E404D, E432D I274IM 
102_1142 102_1142 None None   K11R, V35T, E36A, T39E, E40ED, K122E, D123G, K173A, D177E, T200A, Q207E, V245Q, D250S, A272P, K275Q, V276T, E291D, V292I, I293V, P294T, G335D, Y342F, R356K, M357R, G359T, T377M, I380V, K390R, T403I, E404D  
102_1145 102_1145 None None   V35T, E36A, T39E, E40D, S48T, K122E, D123G, S162C, K173A, D177E, T200A, Q207E, R211K, V245Q, I257V, A272P, K277R, T286A, E291D, V292I, I293V, V317A, G335D, R356K, M357R, R358T, G359T, T377R, K390R, A400T, E404D  
102_1146 102_1146 None None   K20R, V35A, V60I, D121H, K122E, I142V, K173S, D177E, T200A, Q207A, R211S, V245Q, A272P, K277R, T286A, E291D, I293V, P294T, G335D, R356K, M357R, G359T, T377Q, K390R, A400V, E404D  
102_1148 102_1148 None None   V35T, E36A, T39E, S48T, D121H, K122E, A158S, K173T, D177DE, T200A, E204K, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E308K, K311R, Q334N, G335D, R356K, G359T, T377L, K390KR, E404D P52PS 
102_1150 102_1150 None None   V35T, E36A, T39E, E40D, I47L, S48T, K122E, D123N, K173T, D177E, I178M, T200A, Q207K, V245Q, D250E, I257V, A272P, K277R, T286A, V292I, I293V, P294S, V317A, G335D, R356K, G359A, T377Q, K390R, A400T, E404D  
102_1151 102_1151 None None   V35T, E36A, T39E, E40D, S48T, K122E, D123S, I135RT, K173T, I195IV, T200A, Q207K, V245Q, A272P, T286A, A288G, E291D, V292I, I293V, P294T, V317VA, Q334H, R356RK, G359T, T377Q, S379A, K390R, E404D  
102_1153 102_1153 None None   V35T, S48T, V60I, K122E, D123S, I135T, K173S, Q174K, T200IV, Q207ADE, R211K, V245Q, E248D, A272P, K281R, L283LI, R284RK, T286A, E291D, V292I, I293V, P294V, Q334H, G335D, R356K, M357R, G359T, K385R, T386IV, K390R, E399D, A400T, E404D, K431T  
102_1158 102_1158 None None   V35T, E36A, T39E, S48E, D123S, I135V, I159V, E169A, K173A, D177E, T200A, Q207K, V245Q, T286A, E291D, I293V, V317A, G335D, R356K, G359T, T377L, K390R, E404D, Q428R, V435A  
102_1260 102_1260 None None   E6D, V35T, E40D, K49R, I50V, V60I, T107S, D121H, K122E, D123E, I142V, D177E, I178L, G196E, T200A, Q207A, R211K, I244V, V245K, A272P, K277R, T286A, E291D, V292I, I293V, P294Q, E297R, Q334E, R356K, G359AT, T377V, S379C, T386I, K390R, A400T, T403I, P421H, K431T, V435Q I434KM 
102_1261 102_1261 None None   E6ED, K11Q, V35T, E36A, T39DE, E53ED, V60I, K122E, D123N, K173A, Q174QK, D177E, I178M, T200E, Q207N, R211K, V245Q, A272P, T286A, E291D, V292I, I293V, Q334H, G335E, R356K, M357T, K366R, T377Q, S379C, A400T  
102_1266 102_1266 None None   V35T, V60I, D121H, K122E, I135T, D177E, T200A, Q207A, R211K, F214L, V245N, D250E, R284K, T286A, P294T, L325I, K390R E53EA, N54NI 
201_1408 201_1408 None None   V35T, T39E, S48T, K122E, D123N, I135K, I142V, K173A, D177E, I178L, T200E, Q207N, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, P294PT, V317VA, Q334H, G335GD, R356K, G359T, T377Q, K390R, E404D S322C 
201_1460 201_1460 None None   V35T, E36A, T39E, E40ED, S48T, K122E, D123S, K166R, K173AV, D177E, I178V, T200A, Q207A, R211K, V245Q, A272P, K277R, T286TA, E291D, V292I, I293V, E297A, G335D, R356K, G359T, T377Q, K388R, K390R, A400T, E404D  
201_1497 201_1497 None None   V35T, E36A, T39E, S48T, K122E, D123N, I135T, K173A, G196E, T200A, Q207E, F214L, V245Q, D250DANT, A272P, K275Q, K277R, T286A, E291D, V292I, I293V, K311KR, Q334H, G335D, R356K, G359T, Q367M, A376S, T377L, K390R, A400T, T403A, E404D  
201_1538 201_1538 None None   V35T, E36A, T39E, K122E, D123N, K173T, Q174K, D177E, I178L, T200A, Q207N, R211KQ, V245K, I257L, A272P, K275R, K277R, T286A, E291D, V292I, I293V, E297D, H315Y, G335D, R356K, G359T, T377Q, K390R, E404D, K431T  
201_1600 201_1600 None None   E6D, V35T, T39E, G45GE, S48T, A98S, I135V, T165I, K173A, Q174K, D177E, T200A, Q207E, F214FL, P243T, V245Q, E248D, D250E, A272S, E291D, V292I, I293V, Q334N, G335D, R356K, G359T, K366R, A376T, T377Q, K390R, A400T, E404D H208HQ 
201_1650 201_1650 None None   V8VI, V35T, E36A, T39E, E40ED, S48T, K122E, D123G, K173A, Q174K, D177E, I178IV, T200A, I202V, R211RKQ, V245Q, A272P, G273R, T286A, E291D, V292I, I293V, K311KR, I329V, Q334H, G335D, R356K, G359T, V365I, A371V, I375A, T377Q, K390R, E399ED, A400T, T403S, E404D, V435A  
201_1668 201_1668 None None   V35T, E36AV, T39E, S48T, K101KR, K122E, D123S, A158S, K173A, D177E, T200A, Q207EK, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E297T, K311R, I329L, G333E, R356K, G359T, T377L, K390R, E404D  
201_1684 201_1684 None None   V35T, T39A, E40D, K49R, K122E, D123S, S162D, K173A, Q174K, D177E, T200A, I202V, Q207A, R211S, F214L, V245Q, A272P, I293V, L310I, E312N, G335D, R356K, M357K, G359S, K366R, T369A, A371V, I375V, A376T, A400T, T403S, E404D, E432D, V435A  
201_1702 201_1702 None None   V35T, E36A, T39E, E53D, K122E, D123S, A158S, K173A, T200A, I202V, Q207K, R211T, V245Q, A272P, K277R, T286A, E291D, I293V, G335D, R356K, G359T, T377L, K390R, E404D, V435A  
201_1710 201_1710 None None   V35T, V60I, K122E, D123S, I135T, K173S, Q174K, D177E, T200A, Q207E, V245K, E248D, D250E, S251DN, A272P, K277R, K281R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, K366R, I375V, T377Q, S379C, K390R, A400T, E404D, V435L  
201_1720 201_1720 None None   V35T, E36A, T39E, S48T, K173T, Q174K, D177E, T200A, E203D, Q207A, R211K, V245Q, E248D, D250E, A272P, K277R, E291D, V292I, I293V, Q334QH, G335D, R356K, G359T, T377M, K390R, A400T, E404D, E432D  
201_1744 201_1744 None None   E28R, K32E, V35T, E36A, T39E, S48T, K122E, S162A, K173N, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, G335D, R356K, G359T, K366R, T377M, K390R, A400T, V435A, A437V  
201_1750 201_1750 None None   V35T, E36A, T39D, S48T, V60I, K122E, D123N, K166R, K173KE, Q174QR, T200A, Q207E, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, M357V, G359T, K366R, T377Q, K390R, A400T, E404D  
201_1762 201_1762 None None   V35T, E36A, T39E, E40D, K122E, D123G, K173T, D177E, T200A, Q207E, V245Q, A272P, K281R, T286A, E291D, V292I, G335D, R356K, G359T, K366R, T377Q, K390R, E404D, I434M, V435A, A437V  
201_1789 201_1789 None None   V35T, E36EA, T39E, S48T, V60I, K64KR, K122E, D123S, I135IATV, S162CHRY, E169A, K173AT, D177E, T200A, Q207E, R211K, V245Q, D250E, A272P, K277KR, K281KR, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, E370G, T377M, K390R, E404D  
201_1800 201_1800 None None   V35T, E36EA, T39E, S48T, K102Q, D121H, K122E, K173A, D177E, I178L, I195L, Q197K, T200A, I202V, Q207E, V245Q, A272K, K277R, T286A, E291D, V292I, I293V, P294T, Q334H, G335D, R356K, G359T, T377M, K390R, E404D, K431T  
201_1810 201_1810 None None   K11T, V35T, K122E, D123S, K173AS, D177E, V179I, Q207A, R211S, V245KQ, E248D, S251SI, E291D, I293V, P294T, E312D, V317A, G335D, M357K, G359A, K366R, A371V, I375V, A376V, T377M, A400T, T403M, E404D, E432D, G436E  
201_1826 201_1826 None None   K20KR, T27S, V35T, E36A, T39E, K122E, D123G, A158AS, K173T, D177E, T200A, Q207E, R211K, V245Q, E248T, A272P, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, T377Q, K390R, E404D, E413ED, V435A  
201_1856 201_1856 None None   V35T, E36EA, T39E, S48T, K122E, D123G, K173AITV, Q174K, D177E, Q197K, T200A, Q207E, R211K, V245Q, E248D, A272P, K277R, T286TA, E291D, V292I, Q334N, G335D, R356K, G359T, T377Q, K390R, A400T, E404D  
201_1864 201_1864 None None   V35T, E36A, T39E, E40D, K122E, D123G, K173A, D177E, T200A, Q207E, R211K, K238R, V245Q, A272S, K275R, K277R, T286TA, E291D, V292VI, I293V, P294T, H315Y, Q334H, G335D, Y342F, R356K, M357V, G359T, A360T, K366R, T377L, K390R, E404D  
201_1876 201_1876 None None   V35T, E36A, T39E, E40D, K43R, S48T, K122E, D123DGNS, I142IT, A158AS, K166KR, K173A, D177E, T200A, Q207E, R211RK, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, G335D, R356K, M357MR, G359T, K366R, T377LQ, K390R, E404D  
201_1884 201_1884 None None   V35T, E36A, T39E, S48T, K122E, D123S, I135T, S162A, K173T, D177E, T200A, Q207E, V245Q, A272P, K277R, T286A, V292I, I293V, P294S, G335D, R356K, G359T, K366R, T377Q, K390R, E404D  
201_1888 201_1888 None None   V35T, E36A, T39E, S48T, V60I, A158S, K173T, Q174K, D177E, I178IM, V179VI, T200A, Q207E, R211K, V245Q, A272P, T286A, E291D, V292I, I293V, L310I, D324DE, Q334N, G335D, R356K, M357R, G359T, T377Q, S379SC, K390R, E404D, V435A  
201_1898 201_1898 None None   V35T, E36A, T39E, S48T, Q145C, K173A, Q174K, T200A, Q207E, R211K, V245Q, D250E, S251DN, A272P, K277R, T286V, A288T, E291D, V292I, I293V, G335D, F346FHLY, R356K, R358RK, G359NT, K366R, A376AT, T377M, K390R, A400T, T403TI, E404D  
201_1920 201_1920 None None   V35T, T39E, A98S, K173T, D177E, T200A, Q207E, R211K, V245Q, E248ED, D250E, S251SG, A272P, K277R, K281R, E291D, V292I, I293V, D324E, G335D, R356K, G359T, T377Q, K388R, K390R, A400T, E404D  
201_1925 201_1925 None None   V35T, T39N, K122E, D123S, R125RK, I135V, K173L, Q174K, Q207T, R211K, V245Q, A272P, E291D, V292I, I293V, Q334N, G335D, R356K, M357R, G359T, T369A, T377L, K385R, K390R, K395R, E404D  
201_1928 201_1928 None None   V35T, E36A, T39E, I47L, S48T, V60I, K122E, D123N, I135T, K173A, Q174R, D177DE, T200A, Q207N, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, L301LF, Q334QH, G335D, R356K, M357I, G359T, T377M, K390R, A400T, E404D, E413D, V435P  
201_1931 201_1931 None None   T27S, V35T, E36A, T39E, S48T, K102KR, K122E, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, K311R, V317A, D324E, Q334H, G335D, R356K, G359T, T377L, K390R, E404D, V435P  
201_1991 201_1991 None None   V35T, T39L, K122E, S162C, E169T, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, V245Q, E248N, D250E, A272P, E291D, V292I, I293V, Q334H, G335D, R356RK, M357R, G359T, A376T, T377M, K390R, A400T, E404D, K431T, V435A  
201_280 201_280 None None   V35T, T39E, S48T, K122E, K173T, D177E, T200A, Q207E, V245Q, D250E, S251A, A272P, K277R, T286A, E291D, V292I, I293V, E297A, L301F, Q334H, G335D, R356K, R358K, G359T, K366KR, I375V, T377Q, S379SC, K390R, A400T, E404D, V417VI  
201_4018 201_4018 None None   K11T, V35T, K49R, V60I, D121Y, K122E, D177E, I178L, V179I, E194D, G196E, T200I, Q207G, R211K, K238R, V245Q, D250DE, K259KN, L260I, A272S, K275KQ, K277R, L282C, I293V, G335D, P345Q, F346Y, R356K, M357R, A360T, T377Q, S379C, K390R, A400T, W406C K281KE, G285GE 
201_4019 201_4019 None None   V35K, T39E, S48T, A158S, K173A, D177E, I178V, V179I, T200A, Q207EK, R211K, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, Q334H, G335D, R356K, G359T, Q367M, T377L, K390R, E404D  
201_4024 201_4024 None None  Y181C V35T, T39E, K104KN, T107P, D121H, K122E, T139A, A158S, T165P, I167F, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, V245Q, K281R, T286A, E291D, P294T, G335D, I341IV, R356K, M357R, G359T, A371V, I375V, T377L, K390R, E404D L80LF, L120FS, P133L, N136T, R143K 
201_4027 201_4027 None None   V21I, V35T, T39A, V60I, K122E, D123N, I135T, E138A, I142V, S162H, K173S, Q174QK, D177DEG, V179I, Q207A, V245Q, A272P, E291D, I293V, E312D, G335D, R356K, M357R, G359S, E370D, T377M, S379C, T386V, A400T, T403M, E404D  
201_4093 201_4093 None None   V35T, T39E, E40D, I47L, K49KR, V60I, K122E, D123S, I135T, S162A, K173A, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, K311R, P321S, D324E, G335D, R356K, G359T, K366R, T369A, T377L, K390R, A400T, E404D  
201_410 201_410 None None   T27S, V35T, E36A, T39E, I47L, K122E, D123GS, I135R, K173A, Q174K, D177E, T200A, R211K, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, T377L, K390R, A400T, T403A, E404D  
201_4139 201_4139 None None   V35T, E36A, T39E, S48ST, K122E, D123N, K173A, Q174K, D177E, I178IL, T200A, Q207E, R211K, P243T, V245Q, D250E, A272P, V292I, I293V, Q334H, G335D, R356K, M357R, G359T, A376T, T377Q, K390R, A400S, E404D  
201_4155 201_4155 None None   V35T, E36A, T39E, S48T, K82R, K122E, D123N, T139A, A158S, K173A, D177E, T200E, Q207K, F214L, V245Q, D250E, S251N, A272P, I274V, K275R, Q278H, T286A, E291D, V292I, I293V, Q334E, R356K, G359T, T377Q, K390R, A400T, E404D, E432D  
201_4284 201_4284 None None   V35T, E40D, K122E, D123G, K173S, D177E, I178V, T200A, Q207E, V245Q, E248N, A272P, E291D, E312D, G335GD, R356K, M357R, R358K, G359S, E370D, T377M, I380V, A400T, E404D  
201_4318 201_4318 None None   V35T, E36A, T39E, S48T, K122E, D123S, A158S, K173A, Q197K, T200A, Q207E, V245Q, K281R, T286A, K287Q, E291D, V292I, I293V, V317A, G335D, R356K, M357R, G359T, T377L, V381I, K390R, E404D, V435A  
201_4326 201_4326 None None   V35T, E36A, T39E, E40ED, A98AS, K122E, D123NS, K173A, D177E, I195IL, T200A, Q207E, R211K, P243ST, V245Q, A272S, K277R, E291D, V292I, I293V, D324E, Q334D, G335D, Y342F, R356K, M357R, G359T, K366R, A376T, T377Q, K390R, E399D, A400T, E404D  
201_4330 201_4330 None None   K20R, V35T, T39A, S48T, V60I, D121H, K122E, D123S, I135T, K173V, Q174K, D177E, V179I, Q207A, R211S, V245Q, K277R, K281R, T286A, E291D, I293V, P294T, E312D, G335D, M357K, R358K, G359A, T369A, A371V, I375V, A376V, K390R, A400T, T403M, E404D, E432D  
201_4354 201_4354 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123S, T139A, I142V, A158S, K173A, Q174K, D177E, T200A, Q207G, R211RK, V245Q, E248DN, T286A, E291D, V292I, I293V, Q334N, G335D, R356K, G359T, T377Q, K390R, A400T, E404D  
201_4384 201_4384 None None   K32R, V35T, E40D, V60I, A98S, D121H, K122E, D123S, K166R, K173T, G196E, Q197P, T200A, Q207E, V245Q, K277R, E291D, V292I, I293V, P294T, V317VA, G335D, R356K, M357R, G359T, K366R, T377L, K390R, E404D, V435PQ A272*PQS 
201_4414 201_4414 None None   V35T, K49R, V60I, K122E, D123N, I135T, I142V, K166R, K173A, Q174R, D177E, V179I, Q207A, R211S, V245E, K277R, L283I, E291D, I293V, P294A, E312T, G335D, M357Q, G359S, K366R, T369A, I375V, T377LQ, A400T, T403M, E404D, E432D  
201_4419 201_4419 None None   V35T, E36A, T39E, E40D, S48T, K122E, D123NS, A158S, K173A, D177E, T200E, Q207K, V245Q, A272S, L283LI, R284K, E291D, V292I, I293V, P313T, V317A, D324DE, G359S, T377L, V381VI, K390R, E404D L149LF 
201_4438 201_4438 None None   V35T, T39E, E44D, S68G, K122E, D123N, I135T, A158S, K173A, D177E, T200A, Q207E, V245Q, A272P, T286A, E291D, V292I, I293V, D324E, Q334N, G335D, R356K, M357R, G359T, T377L, K390R, E404D D76N 
201_4457 201_4457 None None   E6Q, V35T, K102Q, K103KQ, K122E, D123S, S162CR, K173S, Q174K, D177E, I178IL, V179T, T200A, Q207A, R211S, F214L, V245VL, E248N, K281R, L283I, I293V, P294T, E312N, G335D, E344D, M357R, G359S, T369A, A371V, I375V, A376V, T377L, T386I, E399D, A400T, T403M, E404D, E432D  
201_466 201_466 None None   V35T, E36A, T39A, S48T, K122E, D123GS, I135IT, A158S, K166R, K173A, D177E, T200A, Q207N, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, V317A, Q334H, R356K, R358G, G359T, E370EG, Q373H, T377L, K390R, E404D  
201_706 201_706 None None   K20R, V35T, E36A, T39E, K43R, K49R, K122E, I135T, S162C, K173A, D177E, I178M, T200A, Q207K, R211RK, V245EK, A272P, K277R, T286A, E291D, V292I, Q334H, G335D, R356K, G359T, T377M, K390R, A400T, E404D  
201_817 201_817 None None   V35T, E36A, T39E, S48T, K122E, D123GS, I142V, K173A, Q174K, T200A, Q207A, R211K, V245Q, A272P, K275R, Q278N, T286A, E291D, V292I, I293V, I326V, Q334N, G335D, R356K, M357R, G359A, T377L, K390R, E404D T253S 

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