Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Ndahimana Jd Riedel (2016)
Title HIV drug resistance mutations among patients failing second-line antiretroviral therapy in Rwanda.
Citation Antivir Ther
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 31
NumPts 31
Subtype A, C, B


Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
2029 2029 NRTI NNRTI V75M, L210W, T215Y A98G, K103N K20R, V35K, T39E, K49KR, V60I, K122E, D123S, I135L, E138A, K173L, Q174K, T200A, Q207A, R211N, A272P, T286A, A288AS, E291D, V292I, I293V, P294T, K311R, G335D, M357K, G359S, T369A, A371V, I375A, A376T, T377M, T386A, A400T K275KNRS 
2034 2034 NRTI NNRTI D67N, K70R, T215Y, K219E K101N, K103N, K238T K11T, E28A, V35T, A98S, K122E, D123N, I135T, S162A, K173S, D177E, V179I, T200A, I202V, Q207A, R211S, V245M, D250E, Q278H, E291D, I293V, P294T, E312D, M357K, R358K, G359S, A360T, K366R, T369TI, E370D, A371V, I375V, A376S, T377M, K390R, E399D, A400T  
2036 2036 NRTI NNRTI   E6D, V35T, E36A, T39E, S48T, K122E, I135T, S162A, K173AT, Q174K, D177E, T200A, Q207E, R211RK, V245Q, A272P, K277R, A288S, E291D, I293V, K311KR, V317VA, Q334HN, G335D, R356K, G359S, T377Q, S379C, K390R  
2037 2037 NRTI NNRTI M184V, K219KQ K101E, Y181YC, K238KT E28A, V35T, E40D, K49R, V60VI, A98AS, K122E, D123N, I135T, E138EA, K173S, Q174K, D177E, V179I, T200TA, Q207A, R211S, F214L, H221HY, V245Q, E248D, T286A, E291D, V292VI, I293V, E312D, G335D, I341IV, F346Y, R356K, M357K, R358K, G359S, A360V, A371V, I375V, A376V, E396D, A400T T386TFIS 
2040 2040 NRTI NNRTI M184V A98AG, Y188L V35T, K43KR, V106I, K122E, I135T, K173L, D177E, V179I, I195K, G196E, I202V, Q207D, F214FL, V245Q, D250E, A272P, V276I, K277R, E291D, I293V, G335E, R356K, M357K, G359S, T369A, I375IM, A376T, T377M, S379C, T386I, A400T  
2057 2057 NRTI NNRTI  K103N T39E, E40D, V60I, I142IT, K173IT, D177E, I178L, G196E, T200A, E204K, Q207E, F214L, L228LR, V245Q  
2066 2066 NRTI NNRTI  Y181V E44D, K49R, I50V, V60I, T69TN, K122E, D123S, I135T, K173S, Q174K, D177E, V179I, Q207A, R211RK, F214L, V245Q  
2069 2069 NRTI NNRTI   V60I, K122E, D123S, I135T, K173S, Q174K, D177E, V179I, T200A, Q207AT, R211K  
2075 2075 NRTI NNRTI   V35I, T39TA, K122E, D123S, I135T, I142V, K173S, Q174K, D177E, V179I, Q207A, R211S, F214L, V245Q, I293V, P294T, E312D, G335D, M357K, G359S, A360AT, K366R, T369V, A371V, I375V, A376V, T377M, K390R, A400T S117Q 
2080 2080 NRTI NNRTI  K103KNRS T39TA, S48T, K49KR, V60VI, K122E, D123N, K173A, Q174QK, D177E, T200A, E203D, Q207E, R211K, V245Q  
2109 2109 NRTI NNRTI  K103KN T39E, K43R, S48T, K122E, D123N, T165I, K173A, D177E, T200A, Q207E, R211K, V245Q  
2110 2110 NRTI NNRTI   V60I, K122E, D123NS, I142V, K173S, Q174K, D177E, V179VI, G196E, T200A, Q207A, R211S, V245K  
2111 2111 NRTI NNRTI   T39LS, E40ED, S48T, K103R, V118I, K122E, D123N, E138Q, K173A, D177G, V179S, T200A, Q207E, R211K, F214L, V245Q  
2123 2123 NRTI NNRTI  K103N P4S, E6D, K11T, V35T, V60I, K102Q, V118VI, K122E, D123N, I135T, S162A, K173A, Q174K, D177DE, V179I, Q197K, Q207A, R211S, F214L, V245Q, E248D, A272P, L283I, K287R, I293V, P294T, K311KR, I326IT, G335D, M357K, G359S, K366R, T369A, A371V, I375V, T377M, E399ED, A400T  
2124 2124 NRTI NNRTI M41L, M184V, T215F Y181C K11T, V35IM, T39A, E44D, K49R, D121H, K122E, D123S, I135T, I142T, T165L, K173S, Q174K, D177E, V179I, G196GE, T200TAEK, I202V, Q207A, L228LH, V245Q, K275R, I293V, P294T, E312N, G335D, M357R, G359S, A371V, A376AV, T377M, K390R, A400T  
2127 2127 NRTI NNRTI   T39E, K122E, D123S, I142IV, A158S, K166R, K173A, Q174R, D177E, T200A, Q207E, R211K, V245Q  
2132 2132 NRTI NNRTI D67N, K70R, M184MV, T215TAIV, K219KE K103N, V108I, P225H T39A, V60I, K64KR, T69N, D121H, K122E, D123S, I135T, K173LQ, Q174QK, D177DE, I178IM, T200AE, Q207X  
2133 2133 NRTI NNRTI M41L, D67N, V75M, M184V, L210W, T215Y K101E, G190A T39K, K43E, E53G, V60I, V118I, K122E, D123S, K173L, Q174K, D177DE, I195L, T200A, Q207A, R211T, V245Q N57NK 
2134 2134 NRTI NNRTI  K103N, Y181C T39A, E40D, S48T, T69N, K102Q, V118I, K122E, D123N, I135R, S163T, K173S, Q174K, D177E, I178IL, V179I, T200A, I202IV, Q207A, R211K, F214L, D237DE, V245Q  
2135 2135 NRTI NNRTI   T39A, V60VI, S68NT, K122KE, D123KN, I135T, T139S, I142L, K173S, Q174K, D177E, V179I, G196GE, Q207A, R211S, F214FL, V245Q  
2137 2137 NRTI NNRTI   K49R, V106I, K122E, D123DEG, I135T, T139TA, E169A, K173S, Q174K, D177E, I178L, T200A, Q207A, R211S, F214L, V245Q  
2139 2139 NRTI NNRTI  A98G, Y181C T39E, I47L, S48T, V60I, K122E, D123S, I135T, K173A, D177E, T200A, Q207E, R211K, H221Y, V245E  
2140 2140 NRTI NNRTI M41L, D67N, M184V, T215Y Y181C T39TA, E44D, S48T, K49R, S117A, K122E, D123N, Q145C, K173A, Q174K, D177E, V179I, T200A, I202V, Q207A, H221Y, V245Q  
2141 2141 NRTI NNRTI M41L, D67N, K70R, V75M, M184V, T215F, K219Q P225H, K238T T39A, E40D, V60I, K64R, V118I, K122E, I135T, K173S, Q174K, D177E, T200TA, Q207A, F214L, L228H, E233D, V245E  
2142 2142 NRTI NNRTI   T39E, E40D, E53D, D121H, K122E, K126KR, I135RT, I142V, K173T, Q174K, D177E, T200I, Q207A, R211S, P243PS, V245KN  
2143 2143 NRTI NNRTI  G190A T39E, K49R, I50V, K122E, D123G, I142V, Q145C, A158S, D177E, V179I, T200A, Q207D, R211K, V241I, V245Q  
2158 2158 NRTI NNRTI   I5IV, V35T, V60I, K122E, D123G, I135T, S162A, K173S, Q174K, D177E, V179I, T200A, Q207A, R211RKNS, V245EK, D250E, T286A, L289I, E291D, V292I, I293V, P294T, D324E, G335D, M357R, G359S, T369A, A371V, I375V, A376V, T377M, T386S, A400T  
2159 2159 NRTI NNRTI M41L, M184V, T215F K103S, G190A V35T, V60I, K122E, K173L, Q174K, D177E, V179I, I195L, T200A, I202V, Q207A, R211N, T240K, V245T, E248D, T286A, E291D, V292I, I293V, P294T, E312D, V317A, G335D, M357Q, G359A, T369A, A371V, I375V, T377R, A400T  
2161 2161 NRTI NNRTI   V35T, T39A, E40D, K43KR, S48E, D121Y, K122E, D123G, I135IT, S162A, K173S, Q174K, D177E, I178L, V179I, G196E, Q207A, R211S, V245Q, I274IV, V276VI, E291D, I293V, P294T, P313T, I326T, G335D, M357K, G359S, I375IV, T377L, T386TI, A400T K11KEGR 
2163 2163 NRTI NNRTI   T39M, S48T, V60I, K122KE, D177E, T200I, Q207E, R211K, V245VEIK  
2165 2165 NRTI NNRTI M41L, D67N, V75M, M184V, L210W, T215Y G190S E44D, K49R, V60VI, V111I, K122E, D123N, I135IT, K173S, Q174K, D177E, V179I, T200A, I202V, Q207D