Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Deuzing (2015)
Title Mutation V111I in HIV-2 reverse transcriptase increases the fitness of the nucleoside analogue-resistant K65R and Q151M viruses.
Citation J Virol
SelectedGene RT
SelectedSpecies HIV2
SelectedType Clinical
NumIsolates 72
NumPts 53
Host Human

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
004014_N 004014_N None None   K28R, K64R, P126Q, V135T, H162Y, K173KR, I180L, R200K, V201M, H228X, I251V, K277R, R307K, E322G, K323E, E334D, E344G, E345Q, I348T, E396D, V458I, K468V, V493A, S506V, S508G, V548VI P51S, K147R, L149LV, V167VI, K176P, L212I, L270I, H317C, I365V, I397T, A426V, G431K, A437E, K463R, L486V, T487TA 
005008_N 005008_N None None   M11T, K20R, K64R, D123X, K176Q, I179T, H228Q, I244L, I251R, R307K, E334D, E344G, I348T, E396D, P435S, K468V, S506V, S508G I8M, I10V, R104K, H121D, P126K, L132I, A138V, Q166H, V167I, Y227F, V263I, L270I, R281K, K286R, H317Y, V329I, D332N, E345D, I365V, I397T, D413E, F427Y, K463R, K467R, L486V, K516R 
007004_T 007004_T NRTI None K65R  E6Q, K16KT, D86E, D123N, P126Q, I180L, R200RK, H228K, T237A, I251V, K277R, E334D, V357VI, A437T, K468V, S506V, S508G, E524D V5I, I10V, E29ED, W71WR, I94IT, R104K, H121D, V167I, K176P, D195N, L270I, E304A, E322ED, E345N, I397T, D413E, A426T, K463R, K467R, T487A, K516R 
008002_T 008002_T NRTI None M184V  K28R, K82R, K103KR, P126Q, K142T, H162Y, I180L, H228Q, I244L, I251T, R307K, E334D, V357I, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, K468V, I495V, S506V, S508G, E524D E49K, R104K, R125Q, R165G, K176P, T194TI, D195G, S215T, Y227F, V263I, L270I, R281K, M287L, H317C, E322D, V329I, D332N, Q333L, T360A, I365V, I397T, D413E, A426T, T487A, S515N, K516R, I531V 
009023_T 009023_T NRTI None   M11T, K20R, K82R, P126Q, H162Y, I180L, R200K, H228Q, P272S, K277R, R307K, E334D, V357VI, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, K468V, S506V, S508G, I522IV, E524D, A534AT V5I, R22K, R104K, V167VI, K176P, D195G, Y227F, L270I, H317C, V329I, D332S, I365V, I397T, D413E, A426T, T487A, K492KR, I496V, K516R, I531V 
009024_T 009024_T NRTI None Y115F, M184V, S215SF  M11T, K35R, D86DN, K103KR, P126Q, H162Y, I180L, R200K, D218E, F221L, H228Q, I244L, K275R, R284K, E334D, V357I, A437T, K468V, S506V, S508G, E524D V5I, I10V, R22K, R104K, K176P, D195G, Y227F, L270I, K286KE, H317C, D332S, K340KR, I365V, I397T, D413E, A426T, K463R, K467R, T487A, I531V 
011001_N 011001_N None None   H162Y, R200K, H228R, K277R, E334D, A437T, A483M, S506V K176M, L203W, H317Y, I365V, I397T, K516R 
012021_T 012021_T NRTI None Q151M  P126Q, H162Y, I180L, H228Q, R307K, Q330H, E334D, E344G, E396D, V458I, K468V, V493A, S508G V135I, V167I, K176P, Y227F, L270I, I365V, I397T, D403N, G431K, K463R, I496V, S506I, A507V, K516R, I517L 
   NRTI None Q151M  M11T, K28R, V111I, S117T, P126Q, M164I, I180L, D218E, H228Q, R307K, Q330H, E334D, E344G, E396D, V458I, K468V, V493A, S508G, V548VI I10V, V167I, K176P, Y227F, L270I, H317C, I348V, I365V, I397T, G431K, K463R, K467R, I496V, S506I, A507V, K516R, I517L 
    NRTI None A62AV, K65R, Q151M, M184MV, S215P, I348IV  N69NS, V111I, S117T, P126Q, M164I, I180L, Y227X, H228Q, R307K, H317X, Q330H, E334D, E344G, V357VI, E396D, V458I, K468V, V493A, S508G, V548I V167I, E169EV, K176P, L270I, I365V, I397T, G431K, K463R, K467R, I496V, S506I, A507V, K516R, I517L 
012028_T 012028_T NRTI None M184V, S215F  T58S, D86E, P126Q, K176S, H228Q, I251V, E334D, I341V, E344G, K347R, V357I, P392X, V393X, E394X, R395X, E396X, I397X, W398X, E399X, Q400X, W401X, W402X, D403X, N404X, Y405X, W406X, Q407X, V408X, T409X, W410X, I411X, P412X, D413X, W414X, D415X, F416X, V417X, S418X, T419X, P420X, P421X, L422X, V423X, R424X, L425X, A426X, F427X, N428X, L429X, V430X, G431X, I434L, A437V, K468V, S506V, S508G I90V, H121W, S134A, V201L, L203M, L270I, I365V, K467R, K516R 
012030_T 012030_T NRTI None M184V  E6EQ, M11X, K28KR, P126Q, H162F, I180L, R200K, H228Q, I251V, K277KR, R307RK, L310X, E322EG, K323E, E334D, E344G, E396D, R448K, V458I, K468T, V493A, S506V, S508G I10V, P51S, R78RK, R104K, M164V, V167I, K176P, D195N, Y227F, L270I, R281K, H317C, E345P, I348V, I365V, I397T, A426V, G431K, K463R, L486V 
012040_T 012040_T NRTI None   D86E, D123N, P126Q, H162Y, I180L, R200K, H228Q, I251V, R307K, E334D, A355T, V357I, V417VI, P435Q, K468V, V493A, S506V, S508G H121D, V167I, K176P, Y227F, L270I, Y271YC, A301AT, V329I, K358R, T360A, I365V, I397T, G431K, K463R, L486V, T487A, K516R 
   NRTI None K65R, K70R, Q151M, M184V  K43R, D86E, D123N, P126Q, H162Y, I180L, R200K, Q204X, F214L, H228Q, I251V, R307K, E334D, E344G, A355T, V357I, N404D, P435Q, A437AV, K468V, V493A, S506V, S508G, Q509L, V548I H121D, V167I, K176P, V201VA, Y227F, L270I, V329I, I365V, I397T, G431K, K463R, L486V, T487A 
012049_T 012049_T NRTI None Q151M, M184V  K64R, P126Q, H162Y, E169D, R172RK, K176Q, I251V, K277R, K323E, E334D, E344G, N404D, V458I, K468V, P491S, V493A, S506V, S508G V5I, I10V, A267V, L270I, I365V, I397T, G431K, K463R, S515N, Q558H 
   NRTI None Q151M, M184V  K64R, P126Q, H162Y, E169D, K176Q, I251V, K277R, K323E, E334D, E344G, V357VI, H390X, L391X, P392X, V393X, E394X, R395X, E396X, I397X, W398X, E399X, N404D, V458X, K468V, P491S, V493A, S506V, S508G V2I, V5I, I10V, R22RK, A33AP, R105RK, A267V, L270I, I365V, W402WC, G431K, K463R, S515N, Q558H 
012056_N 012056_N None None  Y227L T163I, I180L, R200K, H228Q, I251T, A327X, T328X, V329X, Q330X, K331X, D332X, Q333X, E334X, N335X, Q336X, W337X, T338X, Y339X, K340X, I341X, H342X, Q343X, E344X, E345X, K347X, I348X, L349X, K350X, V351X, G352X, K353X, Y354X, A355X, K356X, V357X, K358X, N359X, T360X, H361X, T362X, N363X, G364X, I365X, R366X, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, F440Y, K468A, S506V, S508G, Q509R, E524D, V559I K176P, D195G, L270I, H317C, V393VE, I397T, D413E, A426T, K467R, T487A, K516R, I531V, L560C 
012057_T 012057_T NRTI None A62AV, K65R  E6X, D86E, D123N, P126Q, H162Y, I180L, R200K, H228K, T237A, I251V, K277R, E334D, N404D, V417I, P435L, V458VA, K463X, K468I, I495V, S508G, I517V, E523ED, E524EG, V559VA V5I, I10V, P51S, R104K, H121D, V167I, K176P, D195N, L270I, E292EK, E304A, E322D, E345N, I397T, D413E, G431K, K467R, Q471H, L486I, T487A, S506I, K516R, I531V 
   NRTI None A62V, K65R, M184V  N69S, D86E, V111I, D123N, P126Q, H162Y, I180L, R200RK, F214L, H228K, T237TA, I251V, K277R, E334D, N404D, V417I, P435L, V458VA, K463X, K468I, I495V, S508G, I517V, E523ED, E524EG, V559VA R104K, H121D, V167I, K176P, D195N, V201VA, L270I, E304A, E322D, E345N, I397T, D413E, G431K, K467R, Q471H, L486I, T487A, S506I, K516R, I531V 
012058_T 012058_T NRTI None M184V, E219D  M11T, K20R, K82R, H162Y, I180L, R200K, H228Q, I244L, K277R, E334D, V357I, V372I, A437V, K468V, K492N, S506V, E524D V5I, I10V, R22K, R104K, K176P, D195G, Y227F, L270I, H317C, V329I, D332S, T360A, I365V, I397T, D413E, A426T, K463R, T487A, I531V, L560F 
012059_T 012059_T NRTI None   V5L, K9KQ, M11T, K66R, K82R, P126Q, H162Y, I180L, R200K, H228Q, I244L, K277R, L279I, E334D, V357I, V458VA, V466VA, K468V, S506V, S508G, I517IV, E524D I10V, R22K, R104K, V167VI, K176P, D195G, V201VA, Y227F, V263I, L270I, E300G, V329I, Q330L, D332N, K358R, I365V, I397T, D413E, A426T, K463KR, K467R, T487A, K516R, I531V 
012062_T 012062_T NRTI None D67N, K70T, M184V, S215Y, E219D  T58S, K82R, V111I, P126Q, H162Y, I180L, R200K, V201M, H228Q, I244L, R284K, R307RK, E334D, A437T, K468V, S506V, E524D R104K, V167I, K176P, I189L, D195G, L196F, L205M, D224E, Y227F, H317C, V329I, D332S, I365V, I397T, D413E, A426T, K463R, K467R, T487A, K516R 
012064_T 012064_T NRTI None K65R, K70R  K82R, V111VI, P126Q, H162Y, T163TA, I180L, R200RK, L209X, H228K, I251N, I274V, H278N, E334D, V357I, K388KR, G431GE, I434L, A437T, K468V, S506X, E524D R104K, K176P, D195G, Y227F, T237S, L270I, R281K, D332S, I365V, I397T, D413E, A426T, K463R, T487A, K516R 
   NRTI None A62V, K65R, M184V  M11T, K20R, N69S, K82R, V111I, P126Q, H162Y, I180L, H228K, I251N, I274V, H278N, E334D, V357I, K388KR, I434L, G436X, A437T, K468V, S506V, E524D I10V, R22K, R104K, A138E, K176P, D195G, Y227F, T237S, E250ED, L270I, R281K, D332S, I365V, I397T, D413E, A426T, K463R, T487A, K516KR 
012068_N 012068_N None None   M11T, P126Q, A138S, H162Y, K173R, I180L, H228Q, I251V, H278HN, R307K, K323E, E334D, I341V, E344G, K347KR, V357I, E396D, V458I, K468I, V493A, S506V, S508G, K527KR P1A, V5I, I10V, R104K, H121D, E122K, V167I, K176P, D195N, Y227F, L270I, R281RK, K286R, H317C, T360A, I365V, I397T, D413E, G431K, K463R, K467R, Q471R, I496V, S515N, K516KR 
012095_N 012095_N None None   K35KR, P126Q, V135T, H162Y, I180L, I251V, R307K, E334D, E344G, V357I, N359H, I382IV, N404D, W406WR, I434IT, P435PL, F440FL, R448RK, K468V, G490X, V493A, S506V, S508G V5I, I8IV, P51PS, I90V, V167I, K176P, L270I, M287L, Q330L, I397T, G431K, K463R, K467R 
013013_N 013013_N None None   E6ED, M11T, K20R, K64R, K102KN, P126Q, K176Q, Q248N, I251V, Y271H, K277R, R307K, E334D, E344G, N404D, I434IL, P435PL, A437X, K454R, V458I, K468V, S506V, S508G, E524D, V548VA V5I, P51S, I90IV, R104RK, V167I, L270I, D332N, I365V, F389Y, I397T, G431K, K463R, K467R, L486V, T487A, K516R 
  013013_T NRTI None A62V, K65R  K20R, K64R, T88S, V111I, P126Q, K176Q, Q248N, I251V, Y271H, I274X, K275X, T276X, K277X, H278X, L279X, C280X, R281X, L282X, I283X, R284X, G285X, K286X, M287X, T288X, L289X, T290X, E291X, E292X, V293X, Q294X, W295X, T296X, E297X, L298X, A299X, E300X, A301X, E302X, L303X, E304X, E305X, N306X, R307X, I308X, I309X, L310X, S311X, Q312X, E313X, Q314X, E315X, G316X, H317X, Y318X, Y319X, Q320X, E321X, E322X, K323X, E324X, L325X, E326X, A327X, T328X, V329X, Q330X, K331X, D332X, Q333X, E334X, N335X, Q336X, W337X, T338X, Y339X, K340X, I341X, H342X, Q343X, E344X, E345X, K347X, I348X, L349X, K350X, V351X, G352X, K353X, Y354X, A355X, K356X, V357X, K358X, N359X, T360X, H361X, T362X, N363X, G364X, I365X, R366X, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, N404D, I434L, A437I, K454R, V458I, K468V, S506V, S508G, E524D R22K, P51S, I90IV, V167I, L270I, I397T, G431K, K463R, L486V, T487A, I496V, K516R 
013025_T 013025_T NRTI None K65R, M184V  K64R, V111I, P126Q, A138S, H162Y, K176Q, L208X, H228Q, I251V, K277R, E334D, E344G, V357I, V458I, K468V, S506V, S508G, E547K V83A, S134A, Y227F, L270I, M287L, I365V, I397T, K467R, S515N, K516R, I531V 
   NRTI None K65R I181V E48Q, K64R, V111I, P126Q, A138S, H162Y, K176Q, H228Q, M230MI, I251V, K277R, R307K, E334D, E344G, K347R, V357I, V458I, K468V, S506V, S508G, H550R I10V, M11L, I75V, S134A, Y227F, L270I, M287L, E321EG, I365V, I397T, K463R, S515N, K516R, I531V 
    NRTI None K65R I181IV E48Q, K64R, K103KR, V111I, P126Q, A138S, H162Y, K176Q, H228Q, I251IV, K277R, M287X, R307RK, E334D, E344G, V357I, V458I, K468V, V493VA, I495IV, S506V, S508G, S515X, H550HR I75V, R104RG, P119PA, S134A, Y227F, L270I, I365V, I397T, K463R, K516R, I531V 
013042_N 013042_N None None   M11T, K20R, E36ED, D86DE, H121C, D123E, P126Q, H162HY, I180L, R200K, H228Q, I244L, I251IV, E324EG, E334D, N335ND, T338X, E399D, K465KR, K468V, S506X, E524D, V548VI V2VI, V5I, I10V, R22K, P51S, R104K, V135I, V167VI, K176P, D195G, L203M, Y227F, L270I, L279LF, R281K, H317C, V329I, D332S, P392PQ, I397T, D413E, A426T, G436GS, C446CF, K467KR, T487A, S515SN, K516R, I531V 
018001_T 018001_T NRTI None K70R, M184V Y227L M11T, K82R, P126Q, E139EK, I180L, R200K, H228K, I244L, Q248K, I274X, K275X, T276X, K277X, H278X, L279X, C280X, R281X, L282X, I283X, R284X, G285X, K286X, M287X, T288X, L289X, T290X, E291X, E292X, V293X, Q294X, W295X, T296X, E297X, L298X, A299X, E300X, A301X, E302X, L303X, E304X, E305X, N306X, R307X, I308X, I309X, L310X, S311X, Q312X, E313X, Q314X, E315X, G316X, H317X, Y318X, Y319X, Q320X, E321X, E322X, K323X, E324X, L325X, E326X, A327X, T328X, V329X, Q330X, K331X, D332X, Q333X, E334X, N335X, Q336X, W337X, T338X, Y339X, K340X, I341X, H342X, Q343X, E344X, E345X, K347X, I348X, L349X, K350X, V351X, G352X, K353X, Y354X, A355X, K356X, V357X, K358X, N359X, T360X, H361X, T362X, N363X, G364X, I365X, R366X, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, V458I, K468V, S506V, E524D I10V, R22K, R104K, K176P, D195N, L270I, I397T, D413E, A426T, T487A, S515N, K516R, I531V, L560C 
   NRTI None M184MI  M11T, K20KR, K82R, P126Q, H162HY, I180L, D195X, R200K, Y227X, H228X, I244L, A327AV, E334ED, V357I, A437AT, V458I, K468V, S506V, E524D I10V, R22RK, R104K, K176P, L270I, M287L, H317C, V329I, D332S, E345ED, T360TA, I365V, I397T, D413E, P421PR, A426T, K463KR, K467KR, T487A, K516R, I531V, L560C 
018024_N 018024_N None None   P126Q, H162Y, I180L, H228Q, I251T, L279I, R307K, E334D, E344G, V357I, W398X, E399X, Q400X, W401X, W402X, D403X, N404X, Y405X, W406X, Q407X, V408X, T409X, W410X, I411X, P412X, D413X, W414X, D415X, F416X, V417X, S418X, T419X, P420X, P421X, L422X, V423X, R424X, L425X, A426X, F427X, N428X, L429X, G431E, K468I, S508G, K528R, V533I V167I, L168I, K176P, L270I, M287L, D332S, I365V, K463R, L486I, S506I, A507T, K516R 
  018024_T NRTI None M184V  E6Q, M11T, K43R, P126Q, H162Y, I180L, H228Q, I251T, L279I, E297ED, R307K, E334D, E344G, V357I, N404D, V417I, K468I, V493VA, S508G, K528R, V533I V5I, I10V, V167I, L168I, K176P, L270I, M287L, D332S, I365V, I397T, G431K, K463R, L486I, S506I, A507T, K516KR 
018026_N 018026_N None None   K82R, P126Q, H162F, I180L, R200K, H228Q, I244L, R307K, Q333A, E334D, V357I, I375V, G431R, K468V, V493A, S506V, E524D R104K, V135I, V167I, K176P, D195G, Y227F, L270I, R281K, M287L, H317C, E322D, V329I, Q330L, D332S, I365V, I397T, D413E, A426T, K463R, K467R, T487A, K516KR, I531V 
018034_N 018034_N None None   M11T, K20R, H162Y, I180L, R200RK, H228Q, I274X, K275X, T276X, K277X, H278X, L279X, C280X, R281X, L282X, I283X, R284X, G285X, K286X, M287X, T288X, L289X, T290X, E291X, E292X, V293X, Q294X, W295X, T296X, E297X, L298X, A299X, E300X, A301X, E302X, L303X, E304X, E305X, N306X, R307X, I308X, I309X, L310X, S311X, Q312X, E313X, Q314X, E315X, G316X, H317X, Y318X, Y319X, Q320X, E321X, E322X, K323X, E324X, L325X, E326X, A327X, T328X, V329X, Q330X, K331X, D332X, Q333X, E334X, N335X, Q336X, W337X, T338X, Y339X, K340X, I341X, H342X, Q343X, E344X, E345X, K347X, I348X, L349X, K350X, V351X, G352X, K353X, Y354X, A355X, K356X, V357X, K358X, N359X, T360X, H361X, T362X, N363X, G364X, I365X, R366X, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, E396X, I397X, A437X, K468X, V493A, S506V, E524D, V548VI, V559VI K4R, V5I, I10V, R22K, P51S, R104K, E122EK, K176P, D195G, Y227F, P392PQ, V393R, E394G, R395V, D413E, A426T, G431K, K463R, T487A, A507T, K516R, I531V, H550HY 
019018_T 019018_T NRTI None   M11T, K20R, K28R, K35R, F87L, P126Q, I180L, R200K, H228Q, R307K, A437V, K468V, E524D V5I, I10V, R22K, R104K, A138I, K176P, D195G, Y227F, L270I, E324D, I365V, I397T, A426T, K463R, K467R, T487A, K492E, S506I, A507T, K516R, I531V 
022006_N 022006_N None None   M11T, K43R, D86E, P126Q, H162Y, I180L, H228Q, I251V, E334D, I341V, E344G, E396D, T409S, V458I, K468V, V493A, S506V, S508G V2I, V5I, I10V, R104K, K176P, L270I, H317N, I365V, I397T, A426V, G431K, G436D, K463R, K467R, L486V, K516R 
026006_T 026006_T NRTI None Q151M  K64R, K82R, K103R, P126Q, H162Y, K176Q, I179X, H228Q, I251V, R307K, E334D, E344G, V357I, E396D, N404D, A437V, V458I, K468V, V493A, S506V, S508G, E524D V5I, I8IM, I10V, L212LI, V254VG, G262GC, L270I, S311G, I365V, Q370H, I397T, Y405F, A426V, G431K, K463R, K467R, L486V, T487A, I496V 
   NRTI None Q151M  K64R, K82KR, K103R, P126Q, H162Y, K176Q, I179T, H228Q, I251V, V254VI, R307K, E334D, E344G, V357I, E396D, W398X, E399X, Q400X, W401X, W402X, D403X, N404X, Y405X, W406X, Q407X, V408X, T409X, W410X, I411X, P412X, D413X, W414X, D415X, F416X, V417X, S418X, T419X, P420X, P421X, L422X, V423X, R424X, L425X, A426X, F427X, N428X, L429X, V430X, G431R, A437V, K454KR, V458VI, K468V, V493A, S506V, S508G, E524D V5I, I10V, P51PS, L270I, S311G, I365V, Q370H, R385RK, V393VI, I397T, K463R, K467R, L486V, T487A, I496V 
    NRTI None K65R, Q151M  K64R, K82KR, K103R, V111VI, P126Q, H162HY, K176Q, I179T, H228Q, I251V, R307K, E334D, E344G, V357I, E396X, W398X, E399X, Q400X, W401X, W402X, D403X, N404X, Y405X, W406X, Q407X, V408X, T409X, W410X, I411X, P412X, D413X, W414X, D415X, F416X, V417X, S418X, T419X, P420X, P421X, L422X, V423X, R424X, L425X, A426X, F427X, N428X, L429X, V430X, G431E, A437V, K454KR, V458VI, K468V, V493A, S506V, S508G, E524D, Q554QK V5I, I10V, V202VA, L212LI, L270I, S311G, I365V, Q370H, R385RK, I397T, K463R, K467R, L486V, T487A, I496V, G555S, I556R, R557H 
028001_T 028001_T NRTI None K65KR, Q151M  N69NS, K82R, D86E, P126Q, I180L, R200K, H228Q, I251V, K277R, R307K, E334D, E344G, V357I, K388KR, V458I, K468V, T487X, V493A, S506V, S508G E122EK, K176P, L270I, I365V, I397T, G431K, K463R, K467R, L486V 
   NRTI None K65R  M11T, E42EG, N69S, K82R, D86DE, V111I, P126Q, Q151X, I180L, R200K, H228Q, I251V, K277R, L303LI, R307K, A327AV, E334D, E344G, V357I, V372VI, K388KR, V393X, E394X, R395X, E396X, I397X, W398X, E399X, Q400X, W401X, W402X, D403X, N404X, Y405X, W406X, Q407X, V408X, T409X, W410X, I411X, P412X, D413X, W414X, D415X, F416X, V417X, S418X, T419X, P420X, P421X, L422X, V423X, R424X, L425X, A426X, F427X, N428X, L429X, V430X, G431X, V458VI, K468V, V493A, S506V, S508G K4R, K9R, I10V, R78RK, E122K, V167I, K176P, L270I, I365V, K463R, K467R, L486V, T487TA, E547EQ 
    NRTI None A62AV, K65R, F77FL, Q151M, S215ST  M11T, K35KR, N69S, K82R, D86DE, V111I, P126Q, I180L, R200K, H228Q, I251V, K277R, R307K, E334D, E344G, V357I, P392X, V393X, E394X, R395X, E396X, I397X, W398X, E399X, Q400X, W401X, W402X, D403X, N404X, Y405X, W406X, Q407X, V408X, T409X, W410X, I411X, P412X, D413X, W414X, D415X, F416X, V417X, S418X, T419X, P420X, P421X, L422X, V423X, R424X, L425X, A426X, F427X, N428X, L429X, V430X, G431X, V458I, K468V, L486X, V493A, S506V, S508G K4R, K9R, I10V, E122EK, V167I, K176P, I179IV, L270I, I365V, K463R, K467R, T487TA 
028006_T 028006_T NRTI None K65R, K70R, Q151M, M184V  K82R, V111I, F124FL, P126Q, H162Y, R200K, H228Q, I244L, Q245X, L246X, P247X, Q248X, K249X, E250X, I251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, V263X, L264X, N265X, W266X, A267X, A268X, Q269X, L270X, Y271X, P272X, G273X, I274X, K275X, T276X, K277X, H278X, L279X, C280X, R281X, L282X, I283X, R284X, G285X, K286X, M287X, T288X, L289X, T290X, E291X, E292X, V293X, Q294X, W295X, T296X, E297X, L298X, A299X, E300X, A301X, E302X, L303X, E304X, E305X, N306X, R307X, I308X, I309X, L310X, S311X, Q312X, E313X, Q314X, E315X, G316X, H317X, Y318X, Y319X, Q320X, E321X, E322X, K323X, E324X, L325X, E326X, A327X, T328X, V329X, Q330X, K331X, D332X, Q333X, E334X, N335X, Q336X, W337X, T338X, Y339X, K340X, I341X, H342X, Q343X, E344X, E345X, K347X, I348X, L349X, K350X, V351X, G352X, K353X, Y354X, A355X, K356X, V357X, K358X, N359X, T360X, H361X, T362X, N363X, G364X, I365X, R366X, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, V417I, G431X, F440Y, K468V, S506V, S508G, N519D, E524D N69T, R104K, K176P, D195G, L212I, Y227F, E394ED, I397T, P412PA, A426T, L429LI, K467R, T487A, I531V 
028010_T 028010_T NRTI None M184V  K82R, H121Y, D123N, P126Q, H162Y, I180L, H228Q, I244L, L279I, R307K, E334D, V357I, V417I, E452EG, K454KI, V458VA, K468V, S506V, E524D R104K, V135I, K147R, K176P, D195N, Y227F, L270I, H317C, D332N, E345G, K358R, T360A, I365V, V393VE, I397T, D413E, A426T, K467KR, T487A, S508A, K516R, I531V 
   NRTI None K65R, M184V  K82KR, V111VI, H121Y, P126Q, E139EK, H162Y, T163A, I180L, H228Q, L279I, R307K, E334D, V357I, V417I, T442TA, K468V, M503MV, S506V, E524D R78RK, R104K, V135I, K176P, D195N, Y227F, L270I, H317C, E322D, D332N, E345G, K358R, T360A, I365V, I397T, D413E, A426T, T487A, S508A, K516R, I531V 
032004_N 032004_N None None   P126Q, K173KR, R200RK, K223R, H228Q, I251V, R307K, E334D, I341V, E344G, K347R, I386M, N404D, V458I, K465R, I495V, S506V, S508G H121D, E122K, V167I, K176P, V201VA, Y227F, L270I, T360A, I365V, I397T, G431K, K463R, K468M, L486V, I496V, K516R 
  032004_T NRTI None M184V I181IV P126Q, K173KR, R200K, V201I, F221FL, K223R, H228Q, I251V, R307K, E334D, I341V, E344G, K347R, N404D, V458I, K465R, I495V, S506V, S508G, H550HR P51S, H121D, E122K, V167I, K176P, Y227F, G262GC, A267AT, L270I, T360A, I365V, I397T, G431K, K463R, K468M, L486V, I496V, K516KR 
032010_N 032010_N None None   I31IV, T58S, K64R, D86E, D123G, P126Q, V135T, I145IV, H162Y, I180L, K223KR, H228Q, I251IV, H278N, R307K, K323KE, E334D, I341IV, E344G, V357I, N359H, V372VI, R385RQ, T409S, V458I, K468V, V493A, S506V, S508G V2I, V5I, I90V, R104K, V167I, K176P, E250ED, L270I, I283IV, Q330V, I397IT, A426V, G431K, G436D, K463R, K467R, L486V, K516R 
041007_N 041007_N None None   T58S, K64R, P126Q, H162HY, K173KR, I251IV, I283X, R307K, E334D, E344G, V357I, V372A, E396D, A437V, K468V, A483M, V493A, I495V, S506V, S508G I10V, A138M, K176E, L270I, I365V, I397T, K463R, I496V, K516R 
  041007_T NRTI None M184V  T58S, K64KR, D123N, P126Q, H162HY, K173KR, R307K, E334D, E344G, V357I, E396D, A437X, K468V, A483M, V493A, I495V, S506V, S508G I10V, A138M, K176E, L270I, I365V, I397T, K463R, I496V, K516KR 
044001_T 044001_T NRTI None A62V, K65R, M184V  M11T, K35R, N69S, K82R, V111I, D123DN, R125K, P126Q, H162F, I180L, R200K, F214FL, D224DN, H228Q, I244L, I274X, K275X, T276X, K277X, H278X, L279X, C280X, R281X, L282X, I283X, R284X, G285X, K286X, M287X, T288X, L289X, T290X, E291X, E292X, V293X, Q294X, W295X, T296X, E297X, L298X, A299X, E300X, A301X, E302X, L303X, E304X, E305X, N306X, R307X, I308X, I309X, L310X, S311X, Q312X, E313X, Q314X, E315X, G316X, H317X, Y318X, Y319X, Q320X, E321X, E322X, K323X, E324X, L325X, E326X, A327X, T328X, V329X, Q330X, K331X, D332X, Q333X, E334X, N335X, Q336X, W337X, T338X, Y339X, K340X, I341X, H342X, Q343X, E344X, E345X, K347X, I348X, L349X, K350X, V351X, G352X, K353X, Y354X, A355X, K356X, V357X, K358X, N359X, T360X, H361X, T362X, N363X, G364X, I365X, R366X, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, K468V, V493A, S508G, E524D, H550HR V5VI, I10V, R22K, H121D, V167I, K176P, Y227F, L270I, I397T, D413E, A426T, G431K, A437E, K463R, K467R, T487A, I496V, S506I, I531V 
   NRTI None A62V, K65R, M184V  M11T, K20R, K35R, R125K, P126Q, H162F, I180L, R200K, D224N, H228Q, I244L, I274X, K275X, T276X, K277X, H278X, L279X, C280X, R281X, L282X, I283X, R284X, G285X, K286X, M287X, T288X, L289X, T290X, E291X, E292X, V293X, Q294X, W295X, T296X, E297X, L298X, A299X, E300X, A301X, E302X, L303X, E304X, E305X, N306X, R307X, I308X, I309X, L310X, S311X, Q312X, E313X, Q314X, E315X, G316X, H317X, Y318X, Y319X, Q320X, E321X, E322X, K323X, E324X, L325X, E326X, A327X, T328X, V329X, Q330X, K331X, D332X, Q333X, E334X, N335X, Q336X, W337X, T338X, Y339X, K340X, I341X, H342X, Q343X, E344X, E345X, K347X, I348X, L349X, K350X, V351X, G352X, K353X, Y354X, A355X, K356X, V357X, K358X, N359X, T360X, H361X, T362X, N363X, G364X, I365X, R366X, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, G431X, K468V, E470EG, V493X, S508G, E524D, Q554QH V5I, I8M, I10V, L21Q, R22K, H121D, V167I, K176P, Y227F, L270I, E394EQ, I397T, D413E, S418A, A426T, A437E, K463R, K467R, T487TA, I496IV, S506I, I531V 
045008_T 045008_T NRTI None Q151M, M184V  M11T, K28R, K82R, V111I, P126Q, M164I, R172RK, I180L, R200K, Y227X, H228Q, I244L, H317S, E334D, T338S, E344G, V357VI, A437T, K468V, S506V, S508G, E524D, K527KR I10V, R104K, V167I, K176P, D195DG, L270I, R281K, V293I, E322ED, V329I, D332S, I365V, I397T, D413E, A426T, K463R, K467R, T487A, I496IV, I531V 
047003_N 047003_N None None   M11T, K20R, P126Q, I180L, R200K, H228Q, I244L, K277R, K468A, S506V, S508G, E524D V5I, I10V, R22K, P51A, R104K, V167I, K176P, D195G, Y227F, L270I, I397T, D413E, A426T, K463R, K467R, T487A, I531V 
  047003_T NRTI None   M11T, K20R, D86E, P126Q, I180L, R200K, H228Q, I244L, K277R, R307K, Q333E, E334D, A355S, V357I, L391X, K468V, S506V, S508G, E524D V5I, I10V, R22K, P51A, R104K, V167I, K176P, D195G, Y227F, L270I, H317C, V329I, D332S, K358R, T360A, I365V, I397T, D413E, A426T, K463R, K467R, I531V 
   NRTI None   D86E, P126Q, I180L, R200K, H228Q, I244L, K277R, R307K, Q333E, E334D, A355S, V357I, K468V, S506V, S508G, E524D R104K, V167I, K176P, D195G, Y227F, L270I, H317C, V329I, D332S, K358R, T360A, I365V, I397T, D413E, A426T, G436S, K463R, K467R, T487A, I531V 
048009_N 048009_N None None A62V  M11A, A50T, T58S, P126Q, I145V, K176Q, D218E, Y271F, R307K, E334D, E344G, I386V, A437T, F440Y, V458I, D464N, K468I, S506V, S508G, I517V V83A, V135I, I251K, I365V, P392A, I397T, V408I, A426V, F427Y, G431K, K463N, K467R, L486I, K516R 
051010_T 051010_T NRTI None K65R, Q151M  K20R, K64R, N69S, V111I, D123G, P126Q, V135T, A138X, H162Y, I180L, H228Q, I251R, Q333R, E334D, V357I, K468V, E470D, S506V, K516X, E524D, E529EK R22K, A101AV, R104K, H121D, K176P, D195G, Y227F, L270I, H317C, E322D, D332S, I365V, I397T, D413E, A426T, K463R, T487A, K492E, A507T, S508D, S515N, I531V, V533L 
058007_T 058007_T NRTI None M184V  M11T, K20R, K82R, P126Q, V135T, H162Y, I180L, R200K, H228Q, V357I, I386M, A437T, K468V, E524D K4R, V5I, I10V, R104K, V167I, K176P, D195G, Y227F, V263I, L270I, H317C, V329I, E345D, I365V, I397T, D413E, A426T, K463R, K467R, T487A, S506I, A507T, K516R, I531V 
   NRTI None K65R  M11T, K20R, N69S, K82KR, V111I, P126Q, V135T, H162Y, I180L, R200K, H228Q, I251IT, E334D, V357I, I386M, A437T, K468V, S506V, E524D, E547EK, V559X K4R, V5I, I10V, K13KN, P97PL, R104K, V167I, K176P, D195G, Y227F, V263I, L270I, H317C, V329I, D332S, E345D, I365IV, I397T, D413E, A426T, Y441YH, K463R, K467R, T487A, S515N, K516R, I531IV 
063010_T 063010_T NRTI None Q151M, M184V I181V K82R, V111I, P126Q, H162Y, I180L, T194X, F214L, H228Q, I244L, I274V, E334D, V357I, K468V, M484MI, S506V, E524D, V548A, V559I F61FL, R104K, H121W, A138I, K176P, D195G, L212I, Y227F, L270I, D332S, E345ED, T360A, I397T, D413E, A426T, T487A, S515N, K516R, I531V 
   NRTI None K65R, K70R, Q151M I181V K64KR, V111I, P126Q, V135VL, H162Y, R172RK, I180L, H228Q, I244L, I274V, E334D, V357I, N404ND, K468V, S506V, E524D, V548A, V559I F61FL, R104K, H121W, A138I, K176P, D195G, L212I, Y227F, L270I, D332S, E345D, T360A, I397T, D413E, A426T, T487TA, S515N, K516R, I531V 
063015_N 063015_N None None   A3T, M11T, K64R, P126Q, H162Y, K176Q, R200K, G211S, H228Q, H278N, R307K, H317S, K323E, E334D, T338A, E344G, V357I, I386V, N404D, V417I, P435S, K465R, K468V, V493A, S508G, E524D, V533I V5I, I10V, R104K, H121W, V167I, D195E, L270I, R281K, E322K, Q330I, D332N, I348V, K358R, D413E, G431K, A437E, K463R, L486V, T487A, S506I, K516R 
  063015_T NRTI None   A3T, M11T, K64R, P126Q, H162Y, K176Q, R200K, G211S, H228Q, H278N, R307K, H317S, K323E, E334D, T338A, E344G, V357I, I386V, N404D, V417I, P435S, K465R, K468V, V493A, S508G, E524D, V533I V5I, I10V, R104K, H121W, V167I, D195E, L270I, R281K, E322K, Q330I, D332N, I348V, K358R, D413E, G431K, A437E, K463R, L486V, T487A, S506I, K516R 
073004_T 073004_T NRTI None Q151M, M184V  K64R, K82R, P126Q, H162Y, K173R, I180L, F214L, H228Q, R307K, H317S, E334D, T338X, Y339X, K340X, I341X, H342X, Q343X, E344X, E345X, K347X, I348X, L349X, K350X, V351X, G352X, K353X, Y354X, A355X, K356X, V357X, K358X, N359X, T360X, H361X, T362X, N363X, G364X, I365X, R366X, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, A437T, V458I, K468V, S506V, S508G, E524D, H550HR, I556IV, V559I R22K, R104K, V167I, K176P, D195N, Y227F, L270I, Q330L, D332S, I397T, D413E, A426T, K463R, K467R, T487A, K516R, I531V, Q558N 
542001_N 542001_N None None   M11T, P14S, K20R, K28R, K35R, T58S, K64R, K82R, D86E, K103KR, D123X, P126Q, V135T, A138AT, A158T, H162HY, I180L, G211D, H228R, I251IV, H317X, E334D, V357I, V372VI, K468I, S506V, S508G, I517IV, E524D V2I, V5I, I10V, R22K, R104K, V167I, K176P, L270I, I283IV, D332S, I365V, D413DE, V417D, A426T, D432E, T487A, S515SN, K516KR, I531V 
552004_T 552004_T NRTI None Q151M  M11T, K64R, K82R, P126Q, H162Y, I180L, G211GS, F214L, D218E, D224N, H228Q, I251V, R307K, E334D, E344G, V357VI, E396D, N404ND, V417VI, V458I, K468V, V493A, S506V, S508G I10V, V167I, K176P, L212I, L270I, M287V, H317C, I365V, V393VI, I397T, A426V, G431K, A437AE, K463R, L486I, T487A, I496V, A507T, K516R