<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Deuzing (2015)
Title Mutation V111I in HIV-2 reverse transcriptase increases the fitness of the nucleoside analogue-resistant K65R and Q151M viruses.
Citation J Virol
SelectedGene RT
SelectedSpecies HIV2
NumIsolates 72
NumPts 53
Host Human


Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
004014_N 004014_N None None   T11M, K22R, K28R, K64R, K104R, V135T, M138A, K173KR, V201M, F227Y, Q228KR, D250E, I251V, S272P, K277R, E322G, K323E, I329V, G334D, H335N, E344G, E345Q, I348T, I357V, E396D, E413D, V458I, V493A, R516K, V531I, V548VI R20K, P51S, S107T, I108V, A134S, K147R, L149LV, V167VI, G195D, L212I, C232Y, L244I, Y317C, S332D, T426V, G431K, A437E, K463R, V481A, R483A, L486V, A487AT, N515S 
005008_N 005008_N None None   I5V, K22R, K64R, D123NS, Y162H, P176Q, I179T, K200R, D250E, I251R, S272P, G334D, H335N, E344G, I348T, I357V, E396D, P435S, V531I I8M, S107T, I108V, H121D, Q126K, L132I, A134S, M138V, Q166H, V167I, L180I, G195D, C232Y, V263I, R281K, K286R, S332N, E345D, T426A, F427Y, K463R, K467R, V481A, R483A, L486V, A487T, N515S 
007004_T 007004_T NRTI None K65R  E6Q, T11M, K16KT, K22R, D86E, D123N, M138A, Y162H, K200KR, F227Y, Q228K, T237A, D250E, I251V, S272P, K277R, I329V, G334D, H335N, I357IV, V365I, A437T, E524D, V531I R20K, E29ED, W71WR, I94IT, S107T, I108V, H121D, A134S, V167I, G195N, C232Y, L244I, E304A, K307R, Y317H, E322ED, S332D, E345N, K463R, K467R, V481A, R483A, N515S 
008002_T 008002_T NRTI None M184V  K28R, K82R, K103KR, M138A, K142T, K200R, D250E, I251T, S272P, G334D, H335N, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, I495V, E524D E49K, S107T, I108V, R125Q, A134S, R165G, T194TI, S215T, C232Y, V263I, R281K, M287L, Y317C, E322D, S332N, Q333L, T360A, V481A, R483A 
009023_T 009023_T NRTI None   V10I, K82R, M138A, D250E, K277R, G334D, H335N, I357IV, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, I522IV, E524D, A534AT S107T, I108V, A134S, V167VI, C232Y, L244I, Y317C, V481A, R483A, K492KR, I496V, N515S 
009024_T 009024_T NRTI None Y115F, M184V, S215SF  K35R, D86DN, K103KR, M138A, D218E, F221L, D250E, S272P, K275R, R284K, I329V, G334D, H335N, A437T, R516K, E524D R20K, S107T, I108V, A134S, C232Y, K286KE, K307R, Y317C, K340KR, K463R, K467R, V481A, R483A, N515S 
011001_N 011001_N None None   K104R, M138A, F227Y, Q228R, D250E, S272P, K277R, I329V, G334D, H335N, I357V, E413D, A437T, V468K, G508S, V531I S107T, I108V, Q126P, A134S, P176M, L180I, G195D, L203W, C232Y, L244I, I270L, K307R, S332D, T426A, V481A, R483M, A487T, N515S 
012021_T 012021_T NRTI None Q151M  K104R, M138A, K200R, D250E, S272P, I329V, Q330H, G334D, H335N, E344G, I357V, E396D, E413D, V458I, V493A, V531I S107T, I108V, A134S, V135I, V167I, G195D, C232Y, L244I, Y317H, S332D, D403N, T426A, G431K, K463R, V481A, R483A, A487T, I496V, V506I, A507V, N515S, I517L 
   NRTI None Q151M  I5V, K22R, K28R, K104R, V111I, S117T, M138A, Y162H, M164I, K200R, D218E, D250E, S272P, I329V, Q330H, G334D, H335N, E344G, I357V, E396D, E413D, V458I, V493A, V531I, V548VI R20K, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, Y317C, S332D, I348V, T426A, G431K, K463R, K467R, V481A, R483A, A487T, I496V, V506I, A507V, N515S, I517L 
    NRTI None A62AV, K65R, Q151M, M184MV, S215P, I348IV  N69NS, K104R, V111I, S117T, M138A, Y162H, M164I, K200R, F227FI, D250E, S272P, I329V, Q330H, G334D, H335N, E344G, I357IV, E396D, E413D, V458I, V493A, V531I, V548I S107T, I108V, A134S, V167I, E169EV, G195D, C232Y, L244I, Y317YC, S332D, T426A, G431K, K463R, K467R, V481A, R483A, A487T, I496V, V506I, A507V, N515S, I517L 
012028_T 012028_T NRTI None M184V, S215F  T58S, D86E, K104R, M138A, Y162H, P176S, K200R, F227Y, D250E, I251V, S272P, I329V, G334D, H335N, I341V, E344G, K347R, P392X, V393X, E394X, R395X, E396X, T397X, W398X, E399X, Q400X, W401X, W402X, D403X, N404X, Y405X, W406X, Q407X, V408X, T409X, W410X, I411X, P412X, E413X, W414X, D415X, F416X, V417X, S418X, T419X, P420X, P421X, L422X, V423X, R424X, L425X, T426X, F427X, N428X, L429X, V430X, G431X, I434L, A437V, V531I I90V, S107T, I108V, H121W, L180I, G195D, V201L, L203M, C232Y, L244I, K307R, Y317H, S332D, K467R, V481A, R483A, A487T, N515S 
012030_T 012030_T NRTI None M184V  I5V, E6EQ, T11TA, K22R, K28KR, M138A, Y162F, D250E, I251V, S272P, K277KR, L310LIV, E322EG, K323E, I329V, G334D, H335N, E344G, I357V, E396D, E413D, R448K, V458I, V468T, V493A, R516K, V531I R20K, P51S, R78RK, S107T, I108V, A134S, M164V, V167I, G195N, C232Y, L244I, R281K, K307KR, Y317C, S332D, E345P, I348V, T426V, G431K, K463R, V481A, R483A, L486V, A487T, N515S 
012040_T 012040_T NRTI None   D86E, K104R, D123N, M138A, D250E, I251V, S272P, G334D, H335N, A355T, E413D, V417VI, P435Q, V493A, V531I S107T, I108V, H121D, A134S, V167I, G195D, C232Y, L244I, Y271YC, A301AT, Y317H, S332D, K358R, T360A, T426A, G431K, K463R, V481A, R483A, L486V, N515S 
   NRTI None K65R, K70R, Q151M, M184V  K22R, K43R, D86E, K104R, D123N, M138A, F214L, D250E, I251V, S272P, G334D, H335N, E344G, A355T, N404D, E413D, P435Q, A437AV, V493A, Q509L, R516K, V531I, V548I R20K, S107T, I108V, H121D, A134S, V167I, G195D, V201VA, Q204QHR, C232Y, L244I, Y317H, S332D, T426A, G431K, K463R, V481A, R483A, L486V, N515S 
012049_T 012049_T NRTI None Q151M, M184V  T11M, K22R, K64R, K104R, M138A, E169D, R172RK, P176Q, K200R, F227Y, Q228H, D250E, I251V, S272P, K277R, K323E, I329V, G334D, H335N, E344G, I357V, N404D, E413D, V458I, P491S, V493A, R516K, V531I R20K, S107T, I108V, A134S, L180I, G195D, C232Y, L244I, A267V, K307R, Y317H, S332D, T426A, G431K, K463R, V481A, R483A, A487T, Q558H 
   NRTI None Q151M, M184V  T11M, K22KR, K64R, K104R, M138A, E169D, P176Q, K200R, F227Y, Q228H, D250E, I251V, S272P, K277R, K323E, I329V, G334D, H335N, E344G, I357IV, H390X, L391X, P392X, V393X, E394X, R395X, E396X, T397X, W398X, E399X, N404D, E413D, P491S, V493A, R516K, V531I V2I, R20K, A33AP, R105RK, S107T, I108V, A134S, L180I, G195D, C232Y, L244I, A267V, K307R, Y317H, S332D, W402WC, T426A, G431K, V458IM, K463R, V481A, R483A, A487T, Q558H 
012056_N 012056_N None None  F227L Y162H, T163I, D250E, I251T, S272P, A327X, T328X, I329X, Q330X, K331X, S332X, Q333X, G334X, H335X, Q336X, W337X, T338X, Y339X, K340X, I341X, H342X, Q343X, E344X, E345X, K347X, I348X, L349X, K350X, V351X, G352X, K353X, Y354X, A355X, K356X, I357X, K358X, N359X, T360X, H361X, T362X, N363X, G364X, V365X, R366X, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, F440Y, V468A, Q509R, E524D, V559I C232Y, L244I, K307R, Y317C, V393VE, K467R, V481A, R483A, N515S, L560C 
012057_T 012057_T NRTI None A62AV, K65R  T11M, K22R, D86E, D123N, M138A, F227Y, Q228K, T237A, D250E, I251V, S272P, K277R, I329V, G334D, H335N, I357V, V365I, N404D, V417I, P435L, V458VA, V468I, I495V, I517V, E523ED, E524EG, V559VA E6HQ, R20K, P51S, S107T, I108V, H121D, A134S, V167I, G195N, C232Y, L244I, E292EK, E304A, K307R, Y317H, E322D, S332D, E345N, T426A, G431K, K463RS, K467R, Q471H, V481A, R483A, L486I, V506I, N515S 
   NRTI None A62V, K65R, M184V  N69S, D86E, V111I, D123N, M138A, K200KR, F214L, F227Y, Q228K, T237TA, D250E, I251V, S272P, K277R, I329V, G334D, H335N, I357V, V365I, N404D, V417I, P435L, V458VA, V468I, I495V, I517V, E523ED, E524EG, V559VA S107T, I108V, H121D, A134S, V167I, G195N, V201VA, C232Y, L244I, E304A, K307R, Y317H, E322D, S332D, E345N, T426A, G431K, K463RS, K467R, Q471H, V481A, R483A, L486I, V506I, N515S 
012058_T 012058_T NRTI None M184V, E219D  K82R, M138A, D250E, S272P, K277R, G334D, H335N, V372I, A437V, K492N, G508S, R516K, E524D S107T, I108V, Q126P, A134S, C232Y, K307R, Y317C, T360A, K463R, V481A, R483A, N515S, L560F 
012059_T 012059_T NRTI None   I5L, K9KQ, K66R, K82R, M138A, D250E, S272P, K277R, L279I, Q330L, G334D, H335N, V458VA, V466VA, I517IV, E524D R20K, S107T, I108V, A134S, V167VI, V201VA, C232Y, V263I, E300G, K307R, Y317H, S332N, K358R, K463KR, K467R, V481A, R483A, N515S 
012062_T 012062_T NRTI None D67N, K70T, M184V, S215Y, E219D  T58S, K82R, V111I, M138A, V201M, D250E, S272P, R284K, G334D, H335N, I357V, A437T, G508S, E524D, V531I S107T, I108V, A134S, V167I, I189L, L196F, L205M, D224E, C232Y, I270L, K307KR, Y317C, K463R, K467R, V481A, R483A, N515S 
012064_T 012064_T NRTI None K65R, K70R  K82R, V111VI, M138A, T163TA, K200KR, Q228K, D250E, I251N, S272P, I274V, H278N, I329V, G334D, H335N, K388KR, G431GE, I434L, A437T, G508S, E524D, V531I S107T, I108V, A134S, L209LIV, C232Y, T237S, L244I, R281K, K307R, Y317H, K463R, V481A, R483A, V506VI, N515S 
   NRTI None A62V, K65R, M184V  I5V, N69S, K82R, V111I, K200R, Q228K, D250DE, I251N, S272P, I274V, H278N, I329V, G334D, H335N, K388KR, I434L, A437T, G508S, R516RK, E524D, V531I S107T, I108V, A134S, M138E, C232Y, T237S, L244I, R281K, K307R, Y317H, G436GDNS, K463R, V481A, R483A, N515S 
012068_N 012068_N None None   K22R, M138S, K173R, K200R, D250E, I251V, S272P, H278HN, K323E, I329V, G334D, H335N, I341V, E344G, K347KR, E396D, V458I, V468I, V493A, R516RK, K527KR, V531I P1A, R20K, S107T, I108V, H121D, E122K, A134S, V167I, G195N, C232Y, L244I, R281RK, K286R, Y317C, S332D, T360A, T426A, G431K, K463R, K467R, Q471R, V481A, R483A, A487T, I496V 
012095_N 012095_N None None   V10I, T11M, K22R, K35KR, K104R, V135T, M138A, K200R, F227Y, Q228H, D250E, I251V, S272P, I329V, Q330L, G334D, H335N, E344G, N359H, V365I, I382IV, N404D, W406WR, E413D, I434IT, P435PL, F440FL, R448RK, V493A, R516K, V531I I8IV, R20K, P51PS, I90V, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, M287L, Y317H, S332D, T426A, G431K, K463R, K467R, V481A, R483A, A487T, G490GCR, N515S 
013013_N 013013_N None None   E6ED, V10I, K22R, K64R, K102KN, K104KR, M138A, Y162H, P176Q, K200R, F227Y, Q228H, Q248N, D250E, I251V, Y271H, S272P, K277R, I329V, G334D, H335N, E344G, I357V, N404D, E413D, I434IL, P435PL, A437X, K454R, V458I, E524D, V531I, V548VA P51S, I90IV, S107T, I108V, A134S, V167I, L180I, G195D, C232Y, L244I, Y317H, S332N, F389Y, T426A, G431K, K463R, K467R, V481A, R483A, L486V, N515S 
  013013_T NRTI None A62V, K65R  K64R, T88S, K104R, V111I, M138A, Y162H, P176Q, K200R, F227Y, Q228H, Q248N, D250E, I251V, Y271H, S272P, I274X, K275X, T276X, K277X, H278X, L279X, C280X, R281X, L282X, I283X, R284X, G285X, K286X, M287X, T288X, L289X, T290X, E291X, E292X, V293X, Q294X, W295X, T296X, E297X, L298X, A299X, E300X, A301X, E302X, L303X, E304X, E305X, N306X, K307X, I308X, I309X, L310X, S311X, Q312X, E313X, Q314X, E315X, G316X, Y317X, Y318X, Y319X, Q320X, E321X, E322X, K323X, E324X, L325X, E326X, A327X, T328X, I329X, Q330X, K331X, S332X, Q333X, G334X, H335X, Q336X, W337X, T338X, Y339X, K340X, I341X, H342X, Q343X, E344X, E345X, K347X, I348X, L349X, K350X, V351X, G352X, K353X, Y354X, A355X, K356X, I357X, K358X, N359X, T360X, H361X, T362X, N363X, G364X, V365X, R366X, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, N404D, E413D, I434L, A437I, K454R, V458I, E524D, V531I P51S, I90IV, S107T, I108V, A134S, V167I, L180I, G195D, C232Y, L244I, T426A, G431K, K463R, V481A, R483A, L486V, I496V, N515S 
013025_T 013025_T NRTI None K65R, M184V  K64R, K104R, V111I, M138S, P176Q, K200R, D250E, I251V, S272P, K277R, I329V, G334D, H335N, E344G, E413D, V458I, E547K V83A, S107T, I108V, L180I, G195D, L208LFIV, C232Y, L244I, M287L, K307R, Y317H, S332D, T426A, K467R, V481A, R483A, A487T 
   NRTI None K65R I181V I5V, K22R, E48Q, K64R, K104R, V111I, M138S, P176Q, K200R, M230MI, D250E, I251V, S272P, K277R, I329V, G334D, H335N, E344G, K347R, E413D, V458I, H550R T11L, R20K, I75V, S107T, I108V, L180I, G195D, C232Y, L244I, M287L, Y317H, E321EG, S332D, T426A, K463R, V481A, R483A, A487T 
    NRTI None K65R I181IV E48Q, K64R, K103KR, V111I, M138S, P176Q, K200R, D250E, I251IV, S272P, K277R, I329V, G334D, H335N, E344G, E413D, V458I, V493VA, I495IV, H550HR I75V, K104GR, S107T, I108V, P119PA, L180I, G195D, C232Y, L244I, M287LS, K307KR, Y317H, S332D, T426A, K463R, V481A, R483A, A487T, N515NH 
013042_N 013042_N None None   E36ED, D86DE, H121C, D123E, M138A, Y162YH, D250E, I251IV, S272P, E324EG, G334D, H335DN, I357V, V365I, E399D, K465KR, G508S, E524D, V548VI V2VI, P51S, S107T, I108V, A134S, V135I, V167VI, L203M, C232Y, L279LF, R281K, K307R, Y317C, T338TAPS, P392PQ, G436GS, C446CF, K467KR, V481A, R483A, V506VI, N515NS 
018001_T 018001_T NRTI None K70R, M184V F227L I5V, K82R, M138A, E139EK, Y162H, Q228K, Q248K, D250E, S272P, I274X, K275X, T276X, K277X, H278X, L279X, C280X, R281X, L282X, I283X, R284X, G285X, K286X, M287X, T288X, L289X, T290X, E291X, E292X, V293X, Q294X, W295X, T296X, E297X, L298X, A299X, E300X, A301X, E302X, L303X, E304X, E305X, N306X, K307X, I308X, I309X, L310X, S311X, Q312X, E313X, Q314X, E315X, G316X, Y317X, Y318X, Y319X, Q320X, E321X, E322X, K323X, E324X, L325X, E326X, A327X, T328X, I329X, Q330X, K331X, S332X, Q333X, G334X, H335X, Q336X, W337X, T338X, Y339X, K340X, I341X, H342X, Q343X, E344X, E345X, K347X, I348X, L349X, K350X, V351X, G352X, K353X, Y354X, A355X, K356X, I357X, K358X, N359X, T360X, H361X, T362X, N363X, G364X, V365X, R366X, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, V458I, G508S, E524D R20K, S107T, I108V, A134S, G195N, C232Y, V481A, R483A, L560C 
   NRTI None M184MI F227FL I5V, K22KR, K82R, M138A, Y162YH, Q228QK, D250E, S272P, A327AV, G334DE, H335N, A437AT, V458I, G508S, E524D R20RK, S107T, I108V, A134S, G195NS, C232Y, M287L, K307R, Y317C, E345ED, T360TA, P421PR, K463KR, K467KR, V481A, R483A, N515S, L560C 
018024_N 018024_N None None   K104R, M138A, K200R, F227Y, D250E, I251T, S272P, L279I, I329V, G334D, H335N, E344G, T397I, W398X, E399X, Q400X, W401X, W402X, D403X, N404X, Y405X, W406X, Q407X, V408X, T409X, W410X, I411X, P412X, E413X, W414X, D415X, F416X, V417X, S418X, T419X, P420X, P421X, L422X, V423X, R424X, L425X, T426X, F427X, N428X, L429X, G431E, V468I, K528R, V531I, V533I S107T, I108V, A134S, V167I, L168I, G195D, C232Y, L244I, M287L, Y317H, K463R, V481A, R483A, L486I, A487T, V506I, A507T, N515S 
  018024_T NRTI None M184V  E6Q, K22R, K43R, K104R, M138A, K200R, F227Y, D250E, I251T, S272P, L279I, E297ED, I329V, G334D, H335N, E344G, N404D, E413D, V417I, V468I, V493VA, R516RK, K528R, V531I, V533I R20K, S107T, I108V, A134S, V167I, L168I, G195D, C232Y, L244I, M287L, Y317H, T426A, G431K, K463R, V481A, R483A, L486I, A487T, V506I, A507T, N515S 
018026_N 018026_N None None   K82R, M138A, Y162F, D250E, S272P, Q330L, Q333A, G334D, H335N, I375V, G431R, V493A, G508S, R516RK, E524D S107T, I108V, A134S, V135I, V167I, C232Y, R281K, M287L, Y317C, E322D, K463R, K467R, V481A, R483A, N515S 
018034_N 018034_N None None   M138A, K200KR, D250E, S272P, I274X, K275X, T276X, K277X, H278X, L279X, C280X, R281X, L282X, I283X, R284X, G285X, K286X, M287X, T288X, L289X, T290X, E291X, E292X, V293X, Q294X, W295X, T296X, E297X, L298X, A299X, E300X, A301X, E302X, L303X, E304X, E305X, N306X, K307X, I308X, I309X, L310X, S311X, Q312X, E313X, Q314X, E315X, G316X, Y317X, Y318X, Y319X, Q320X, E321X, E322X, K323X, E324X, L325X, E326X, A327X, T328X, I329X, Q330X, K331X, S332X, Q333X, G334X, H335X, Q336X, W337X, T338X, Y339X, K340X, I341X, H342X, Q343X, E344X, E345X, K347X, I348X, L349X, K350X, V351X, G352X, K353X, Y354X, A355X, K356X, I357X, K358X, N359X, T360X, H361X, T362X, N363X, G364X, V365X, R366X, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, A437IT, V468VA, V493A, G508S, E524D, V548VI, V559VI K4R, P51S, S107T, I108V, E122EK, Q126P, A134S, C232Y, L244I, I270L, P392PQ, V393R, E394G, R395V, E396*W, T397GR, G431K, K463R, V481A, R483A, A507T, N515S, H550HY 
019018_T 019018_T NRTI None   K28R, K35R, F87L, Y162H, D250E, S272P, I329V, G334E, H335N, I357V, E413D, A437V, G508S, E524D S107T, I108V, A134S, M138I, C232Y, L244I, Y317H, E324D, S332D, K463R, K467R, V481A, R483A, K492E, V506I, A507T, N515S 
022006_N 022006_N None None   K22R, K43R, D86E, M138A, K200R, F227Y, D250E, I251V, S272P, I329V, G334D, H335N, I341V, E344G, I357V, E396D, T409S, E413D, G436D, V458I, V493A, V531I V2I, R20K, S107T, I108V, A134S, G195D, C232Y, L244I, K307R, Y317N, S332D, T426V, G431K, K463R, K467R, V481A, R483A, L486V, A487T, N515S 
026006_T 026006_T NRTI None Q151M  T11M, K22R, K64R, K82R, K103R, K104R, M138A, P176Q, I179AT, K200R, F227Y, D250E, I251V, S272P, I329V, G334D, H335N, E344G, E396D, N404D, E413D, A437V, V458I, V493A, R516K, E524D, V531I I8IM, R20K, S107T, I108V, A134S, L180I, G195D, L212LI, C232Y, L244I, V254VG, G262GC, S311G, Y317H, S332D, Q370H, Y405F, T426V, G431K, K463R, K467R, V481A, R483A, L486V, I496V, N515S 
   NRTI None Q151M  T11M, K22R, K64R, K82KR, K103R, K104R, M138A, P176Q, I179T, K200R, F227Y, D250E, I251V, V254VI, S272P, I329V, G334D, H335N, E344G, E396D, W398X, E399X, Q400X, W401X, W402X, D403X, N404X, Y405X, W406X, Q407X, V408X, T409X, W410X, I411X, P412X, E413X, W414X, D415X, F416X, V417X, S418X, T419X, P420X, P421X, L422X, V423X, R424X, L425X, T426X, F427X, N428X, L429X, V430X, G431R, A437V, K454KR, V458VI, V493A, R516K, E524D, V531I R20K, P51PS, S107T, I108V, A134S, L180I, G195D, C232Y, L244I, S311G, Y317H, S332D, Q370H, R385RK, V393VI, K463R, K467R, V481A, R483A, L486V, I496V, N515S 
    NRTI None K65R, Q151M  T11M, K22R, K64R, K82KR, K103R, K104R, V111VI, M138A, Y162YH, P176Q, I179T, K200R, F227Y, D250E, I251V, S272P, I329V, G334D, H335N, E344G, W398X, E399X, Q400X, W401X, W402X, D403X, N404X, Y405X, W406X, Q407X, V408X, T409X, W410X, I411X, P412X, E413X, W414X, D415X, F416X, V417X, S418X, T419X, P420X, P421X, L422X, V423X, R424X, L425X, T426X, F427X, N428X, L429X, V430X, G431E, A437V, K454KR, V458VI, V493A, R516K, E524D, V531I, Q554QK R20K, S107T, I108V, A134S, L180I, G195D, V202VA, L212LI, C232Y, L244I, S311G, Y317H, S332D, Q370H, R385RK, E396DV, K463R, K467R, V481A, R483A, L486V, I496V, N515S, G555S 
028001_T 028001_T NRTI None K65KR, Q151M  N69NS, K82R, D86E, K104R, M138A, Y162H, F227Y, D250E, I251V, S272P, K277R, I329V, G334D, H335N, E344G, K388KR, E413D, V458I, V493A, R516K, V531I S107T, I108V, E122EK, A134S, G195D, C232Y, L244I, Y317H, S332D, T426A, G431K, K463R, K467R, V481A, R483A, L486V, A487AITV, N515S 
   NRTI None K65R, Q151MR  I5V, K22R, E42EG, N69S, K82R, D86DE, K104R, V111I, M138A, Y162H, F227Y, D250E, I251V, S272P, K277R, L303LI, A327AV, I329V, G334D, H335N, E344G, V372VI, K388KR, V393X, E394X, R395X, E396X, T397X, W398X, E399X, Q400X, W401X, W402X, D403X, N404X, Y405X, W406X, Q407X, V408X, T409X, W410X, I411X, P412X, E413X, W414X, D415X, F416X, V417X, S418X, T419X, P420X, P421X, L422X, V423X, R424X, L425X, T426X, F427X, N428X, L429X, V430X, G431X, V458VI, V493A, R516K, V531I K4R, K9R, R20K, R78RK, S107T, I108V, E122K, A134S, V167I, G195D, C232Y, L244I, Y317H, S332D, K463R, K467R, V481A, R483A, L486V, A487AT, N515S, E547EQ 
    NRTI None A62AV, K65R, F77FL, Q151M, S215ST  I5V, K22R, K35KR, N69S, K82R, D86DE, K104R, V111I, M138A, Y162H, F227Y, D250E, I251V, S272P, K277R, I329V, G334D, H335N, E344G, P392X, V393X, E394X, R395X, E396X, T397X, W398X, E399X, Q400X, W401X, W402X, D403X, N404X, Y405X, W406X, Q407X, V408X, T409X, W410X, I411X, P412X, E413X, W414X, D415X, F416X, V417X, S418X, T419X, P420X, P421X, L422X, V423X, R424X, L425X, T426X, F427X, N428X, L429X, V430X, G431X, V458I, V493A, R516K, V531I K4R, K9R, R20K, S107T, I108V, E122EK, A134S, V167I, I179IV, G195D, C232Y, L244I, Y317H, S332D, K463R, K467R, V481A, R483A, L486IV, A487AT, N515S 
028006_T 028006_T NRTI None K65R, K70R, Q151M, M184V  K82R, V111I, F124FL, M138A, Q245X, L246X, P247X, Q248X, K249X, D250X, I251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, V263X, L264X, N265X, W266X, A267X, A268X, Q269X, I270X, Y271X, S272X, G273X, I274X, K275X, T276X, K277X, H278X, L279X, C280X, R281X, L282X, I283X, R284X, G285X, K286X, M287X, T288X, L289X, T290X, E291X, E292X, V293X, Q294X, W295X, T296X, E297X, L298X, A299X, E300X, A301X, E302X, L303X, E304X, E305X, N306X, K307X, I308X, I309X, L310X, S311X, Q312X, E313X, Q314X, E315X, G316X, Y317X, Y318X, Y319X, Q320X, E321X, E322X, K323X, E324X, L325X, E326X, A327X, T328X, I329X, Q330X, K331X, S332X, Q333X, G334X, H335X, Q336X, W337X, T338X, Y339X, K340X, I341X, H342X, Q343X, E344X, E345X, K347X, I348X, L349X, K350X, V351X, G352X, K353X, Y354X, A355X, K356X, I357X, K358X, N359X, T360X, H361X, T362X, N363X, G364X, V365X, R366X, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, E413D, V417I, F440Y, R516K, N519D, E524D N69T, S107T, I108V, A134S, L180I, L212I, C232Y, E394ED, P412PA, L429LI, G431KR, K467R, V481A, R483A, N515S 
028010_T 028010_T NRTI None M184V  K82R, H121Y, D123N, M138A, K200R, D250E, S272P, L279I, I329V, G334D, H335N, V417I, E452EG, K454KI, V458VA, E524D S107T, I108V, A134S, V135I, K147R, G195N, C232Y, Y317C, S332N, E345G, K358R, T360A, V393VE, K467KR, V481A, R483A, G508A, N515S 
   NRTI None K65R, M184V  K82KR, V111VI, H121Y, M138A, E139EK, T163A, K200R, D250E, S272P, L279I, I329V, G334D, H335N, V417I, T442TA, M503MV, E524D R78RK, S107T, I108V, A134S, V135I, G195N, C232Y, L244I, Y317C, E322D, S332N, E345G, K358R, T360A, V481A, R483A, G508A, N515S 
032004_N 032004_N None None   K104R, M138A, Y162H, K173KR, K200KR, K223R, D250E, I251V, S272P, I329V, G334D, H335N, I341V, E344G, K347R, I357V, I386M, N404D, E413D, V458I, K465R, I495V, V531I S107T, I108V, H121D, E122K, A134S, V167I, L180I, G195D, V201VA, C232Y, L244I, Y317H, S332D, T360A, T426A, G431K, K463R, V468M, V481A, R483A, L486V, A487T, I496V, N515S 
  032004_T NRTI None M184V I181IV K22R, K104R, M138A, Y162H, K173KR, V201I, F221FL, K223R, D250E, I251V, S272P, I329V, G334D, H335N, I341V, E344G, K347R, I357V, N404D, E413D, V458I, K465R, I495V, R516RK, V531I, H550HR R20K, P51S, S107T, I108V, H121D, E122K, A134S, V167I, L180I, G195D, C232Y, L244I, G262GC, A267AT, Y317H, S332D, T360A, T426A, G431K, K463R, V468M, V481A, R483A, L486V, A487T, I496V, N515S 
032010_N 032010_N None None   V10I, T11M, K22R, I31IV, T58S, K64R, D86E, D123G, V135T, M138A, I145IV, K200R, K223KR, F227Y, D250DE, I251IV, S272P, H278N, K323KE, I329V, G334D, H335N, I341IV, E344G, N359H, V365I, V372VI, R385RQ, T397TI, T409S, E413D, G436D, V458I, V493A, V531I V2I, R20K, I90V, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, I283IV, Y317H, Q330V, S332D, T426V, G431K, K463R, K467R, V481A, R483A, L486V, A487T, N515S 
041007_N 041007_N None None   I5V, T11M, K22R, T58S, K64R, K104R, Y162YH, K173KR, K200R, F227Y, Q228H, D250E, I251IV, S272P, I329V, G334D, H335N, E344G, E396D, E413D, A437V, V493A, I495V, V531I R20K, S107T, I108V, A134S, P176E, L180I, G195D, C232Y, L244I, I283IFL, Y317H, S332D, V372A, T426A, K463R, V481A, R483M, A487T, I496V, N515S 
  041007_T NRTI None M184V  I5V, T11M, K22R, T58S, K64KR, K104R, D123N, Y162YH, K173KR, K200R, F227Y, Q228H, D250E, S272P, I329V, G334D, H335N, E344G, E396D, E413D, A437IV, V493A, I495V, R516RK, V531I R20K, S107T, I108V, A134S, P176E, L180I, G195D, C232Y, L244I, Y317H, S332D, T426A, K463R, V481A, R483M, A487T, I496V, N515S 
044001_T 044001_T NRTI None A62V, K65R, M184V  I5IV, K35R, N69S, K82R, K104R, V111I, D123DN, R125K, M138A, Y162F, F214FL, D224DN, D250E, S272P, I274X, K275X, T276X, K277X, H278X, L279X, C280X, R281X, L282X, I283X, R284X, G285X, K286X, M287X, T288X, L289X, T290X, E291X, E292X, V293X, Q294X, W295X, T296X, E297X, L298X, A299X, E300X, A301X, E302X, L303X, E304X, E305X, N306X, K307X, I308X, I309X, L310X, S311X, Q312X, E313X, Q314X, E315X, G316X, Y317X, Y318X, Y319X, Q320X, E321X, E322X, K323X, E324X, L325X, E326X, A327X, T328X, I329X, Q330X, K331X, S332X, Q333X, G334X, H335X, Q336X, W337X, T338X, Y339X, K340X, I341X, H342X, Q343X, E344X, E345X, K347X, I348X, L349X, K350X, V351X, G352X, K353X, Y354X, A355X, K356X, I357X, K358X, N359X, T360X, H361X, T362X, N363X, G364X, V365X, R366X, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, V493A, R516K, E524D, H550HR R20K, S107T, I108V, H121D, A134S, V167I, G195D, C232Y, G431K, A437E, K463R, K467R, V481A, R483A, I496V, V506I, N515S 
   NRTI None A62V, K65R, M184V  K35R, K104R, R125K, M138A, Y162F, D224N, D250E, S272P, I274X, K275X, T276X, K277X, H278X, L279X, C280X, R281X, L282X, I283X, R284X, G285X, K286X, M287X, T288X, L289X, T290X, E291X, E292X, V293X, Q294X, W295X, T296X, E297X, L298X, A299X, E300X, A301X, E302X, L303X, E304X, E305X, N306X, K307X, I308X, I309X, L310X, S311X, Q312X, E313X, Q314X, E315X, G316X, Y317X, Y318X, Y319X, Q320X, E321X, E322X, K323X, E324X, L325X, E326X, A327X, T328X, I329X, Q330X, K331X, S332X, Q333X, G334X, H335X, Q336X, W337X, T338X, Y339X, K340X, I341X, H342X, Q343X, E344X, E345X, K347X, I348X, L349X, K350X, V351X, G352X, K353X, Y354X, A355X, K356X, I357X, K358X, N359X, T360X, H361X, T362X, N363X, G364X, V365X, R366X, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, E470EG, R516K, E524D, Q554QH I8M, L21Q, S107T, I108V, H121D, A134S, V167I, G195D, C232Y, E394EQ, S418A, G431EK, A437E, K463R, K467R, V481A, R483A, A487AT, V493AT, I496IV, V506I, N515S 
045008_T 045008_T NRTI None Q151M, M184V  I5V, K22R, K28R, K82R, V111I, M138A, Y162H, M164I, R172RK, F227FI, D250E, S272P, Y317S, G334D, H335N, T338S, E344G, I357IV, A437T, R516K, E524D, K527KR R20K, S107T, I108V, A134S, V167I, G195GD, C232Y, R281K, V293I, K307R, E322ED, K463R, K467R, V481A, R483A, I496IV, N515S 
047003_N 047003_N None None   M138A, Y162H, D250E, S272P, K277R, I329V, G334E, H335N, I357V, V365I, V468A, R516K, E524D P51A, S107T, I108V, A134S, V167I, C232Y, K307R, Y317H, S332D, K463R, K467R, V481A, R483A, N515S 
  047003_T NRTI None   D86E, M138A, Y162H, D250E, S272P, K277R, Q333E, G334D, H335N, A355S, L391X, R516K, E524D P51A, S107T, I108V, A134S, V167I, C232Y, Y317C, K358R, T360A, K463R, K467R, V481A, R483A, A487T, N515S 
   NRTI None   D86E, M138A, Y162H, D250E, S272P, K277R, Q333E, G334D, H335N, A355S, R516K, E524D S107T, I108V, A134S, V167I, C232Y, Y317C, K358R, T360A, G436S, K463R, K467R, V481A, R483A, N515S 
048009_N 048009_N None None A62V  I5V, V10I, T11A, K22R, A50T, T58S, K104R, M138A, I145V, Y162H, P176Q, K200R, D218E, F227Y, Q228H, D250E, Y271F, S272P, I329V, G334D, H335N, E344G, I357V, I386V, E413D, A437T, F440Y, V458I, D464N, V468I, I517V, V531I R20K, V83A, S107T, I108V, A134S, V135I, L180I, G195D, C232Y, L244I, I251K, I270L, Y317H, S332D, P392A, V408I, T426V, F427Y, G431K, K463N, K467R, V481A, R483A, L486I, A487T, N515S 
051010_T 051010_T NRTI None K65R, Q151M  K64R, N69S, V111I, D123G, V135T, M138ST, K200R, D250E, I251R, S272P, I329V, Q333R, G334D, H335N, E470D, E524D, E529EK A101AV, S107T, I108V, H121D, A134S, C232Y, L244I, K307R, Y317C, E322D, K463R, V481A, R483A, K492E, A507T, G508D, R516RT, V533L 
058007_T 058007_T NRTI None M184V  K22R, K82R, V135T, M138A, D250E, S272P, G334E, H335N, I386M, A437T, G508S, E524D K4R, S107T, I108V, A134S, V167I, C232Y, L244I, V263I, K307R, Y317C, S332D, E345D, K463R, K467R, V481A, R483A, V506I, A507T, N515S 
   NRTI None K65R  K22R, N69S, K82KR, V111I, V135T, M138A, D250E, I251IT, S272P, G334D, H335N, V365VI, I386M, A437T, G508S, E524D, V531VI, E547EK K4R, K13KN, P97PL, S107T, I108V, A134S, V167I, C232Y, L244I, V263I, K307R, Y317C, E345D, Y441YH, K463R, K467R, V481A, R483A, V559VIM 
063010_T 063010_T NRTI None Q151M, M184V I181V K82R, V111I, K200R, F214L, D250E, S272P, I274V, I329V, G334D, H335N, V365I, M484MI, G508S, E524D, V548A, V559I F61FL, S107T, I108V, H121W, A134S, M138I, T194TIM, L212I, C232Y, K307R, Y317H, E345ED, T360A, V481A, R483A 
   NRTI None K65R, K70R, Q151M I181V K64KR, V111I, V135VL, R172RK, K200R, D250E, S272P, I274V, I329V, G334D, H335N, V365I, N404ND, G508S, E524D, V548A, V559I F61FL, S107T, I108V, H121W, A134S, M138I, L212I, C232Y, K307R, Y317H, E345D, T360A, V481A, R483A, A487AT 
063015_N 063015_N None None   A3T, K22R, K64R, M138A, P176Q, G211S, F227Y, D250E, S272P, H278N, Y317S, K323E, I329V, G334D, H335N, T338A, E344G, V365I, I386V, T397I, N404D, V417I, P435S, K465R, V493A, E524D, V531I, V533I R20K, S107T, I108V, H121W, A134S, V167I, L180I, G195E, C232Y, L244I, R281K, E322K, Q330I, S332N, I348V, K358R, T426A, G431K, A437E, K463R, V481A, R483A, L486V, V506I, N515S 
  063015_T NRTI None   A3T, K22R, K64R, M138A, P176Q, G211S, F227Y, D250E, S272P, H278N, Y317S, K323E, I329V, G334D, H335N, T338A, E344G, V365I, I386V, T397I, N404D, V417I, P435S, K465R, V493A, E524D, V531I, V533I R20K, S107T, I108V, H121W, A134S, V167I, L180I, G195E, C232Y, L244I, R281K, E322K, Q330I, S332N, I348V, K358R, T426A, G431K, A437E, K463R, V481A, R483A, L486V, V506I, N515S 
073004_T 073004_T NRTI None Q151M, M184V  K64R, K82R, M138A, K173R, K200R, F214L, D250E, S272P, Y317S, I329V, Q330L, G334D, H335N, T338X, Y339X, K340X, I341X, H342X, Q343X, E344X, E345X, K347X, I348X, L349X, K350X, V351X, G352X, K353X, Y354X, A355X, K356X, I357X, K358X, N359X, T360X, H361X, T362X, N363X, G364X, V365X, R366X, L367X, L368X, A369X, Q370X, V371X, V372X, Q373X, K374X, I375X, G376X, K377X, E378X, A379X, L380X, V381X, I382X, W383X, G384X, R385X, I386X, P387X, K388X, F389X, H390X, L391X, A437T, V458I, E524D, H550HR, I556IV, V559I R20K, S107T, I108V, A134S, V167I, G195N, C232Y, L244I, K463R, K467R, V481A, R483A, N515S, Q558N 
542001_N 542001_N None None   P14S, K28R, K35R, T58S, K64R, K82R, D86E, K103KR, D123DEG, V135T, M138AT, A158T, Y162YH, K200R, G211D, F227Y, Q228R, D250E, I251IV, S272P, I329V, G334D, H335N, V372VI, T397I, E413ED, V468I, R516RK, I517IV, E524D V2I, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, I283IV, K307R, Y317CS, V417D, D432E, V481A, R483A, N515NS 
552004_T 552004_T NRTI None Q151M  I5V, K22R, K64R, K82R, K104R, M138A, K200R, G211GS, F214L, D218E, D224N, F227Y, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357IV, E396D, N404ND, E413D, V417VI, V458I, V493A, V531I R20K, S107T, I108V, A134S, V167I, G195D, L212I, C232Y, L244I, M287V, Y317C, S332D, V393VI, T426V, G431K, A437AE, K463R, V481A, R483A, L486I, I496V, A507T, N515S