<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Giandhari (2015)
Title Genetic changes in HIV-1 gag-protease associated with protease inhibitor-based therapy failure in pediatric patients.
Citation ARHR
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 40
NumPts 20
Subtype C

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
3018 2005_ZA_3018B None    T12S, I15V, L19I, M36I, R41K, H69K D60G, P81T 
  2006_ZA_3018F LPV 54 V82A L23I T12S, I15V, L19I, K20R, E35D, M36I, R41K, L63P, H69K D60G 
3059 2006_ZA_3059B None    T12S, I15V, L19T, K20R, E35D, M36I, P39T, R41K, L63V, H69K D60G 
  2007_ZA_3059F LPV 39   T12S, I15V, L19T, K20R, E35D, M36I, R41K, L63V, H69K D60G 
5014 2005_ZA_5014B None    T12S, I15V, L19I, H69K, T74S, V77I D60G 
  2006_ZA_5014F LPV 56   T12S, I15V, L19I, H69K, T74S, V77I D60G 
5045 2005_ZA_5045B None    T12S, I15V, L19I, E35D, M36I, R41K, L63P, H69K D60G 
  2006_ZA_5045F LPV 42 V82A  T12S, I15V, L19I, K20R, E35D, M36I, R41K, K45R, L63P, H69K D60G 
5046 2005_ZA_5046B None    T12A, I15V, L19T, M36I, R41K, L63V, I64M, H69K D60G 
  2006_ZA_5046F LPV 53   T12A, I15V, L19T, M36I, R41K, L63V, I64M, H69K D60G 
5050 2005_ZA_5050B None    L19T, M36I, R41K, I62V, L63P, I64L, H69K, K70R  
  2006_ZA_5050F LPV 57   L19T, M36I, R41K, K43E, I62V, L63P, I64L, H69K, K70R, N83S  
5079 2005_ZA_5079B None    L10M, T12S, I15V, L19I, N37K, R41I, L63T, H69K  
  2006_ZA_5079F RTV 39   L10M, T12S, I15V, L19I, N37K, R41I, L63T, H69K, K70R  
5080 2005_ZA_5080B None    T12S, I15V, L19I, M36I, R41K, H69K, V82I  
  2006_ZA_5080F LPV 53   T12S, I15V, L19I, M36I, R41K, H69K, V82I  
5086 2005_ZA_5086B None    T12S, I15V, L19I, K20R, E35D, M36I, R41K, I62V, H69K, T74S  
  2006_ZA_5086F LPV 53 M46I, I54V, V82A  L10I, T12S, I15V, L19I, K20R, E35D, M36I, R41K, Q61H, I62V, L63P, H69K, T74S  
5094 2005_ZA_5094B None    T12S, I15V, L19I, M36I, R41K, L63A, H69K, T74S  
  2006_ZA_5094F RTV 37 M46I, V82A  T12S, I15V, L19I, M36I, R41K, L63T, H69K, T74S  
5117 2006_ZA_5117B None    T12S, I15V, L19I, E35D, M36I, R41K, L63P, H69K, A71T  
  2007_ZA_5117F LPV 53   T12S, I15V, L19I, E35D, M36I, R41K, L63P, H69K, A71T  
5166 2006_ZA_5166B None    I15V, M36I, R41K, H69K T80N, P81T 
  2007_ZA_5166F LPV 41   I15V, M36I, R41K, H69K  
5175 2006_ZA_5175B None    T12S, I15V, L19I, M36L, N37E, L63V, H69K  
  2007_ZA_5175F LPV 37   T12S, I15V, L19I, M36L, N37E, L63V, H69K  
5198 2007_ZA_5198B None    T12S, I15V, L19I, E35D, M36I, R41K, H69K, T74S  
  2007_ZA_5198F LPV 37 M46I, I54V, V82A L33F T12S, I15V, L19I, K20R, E35D, M36I, R41K, H69K, T74S  
5207 2007_ZA_5207B None    L10I, T12S, I15V, L19I, K20R, E35D, M36I, R41K, C67Y, H69K  
  2007_ZA_5207F RTV 32 V82A  L10I, I15V, L19I, K20R, E35D, M36I, R41K, D60E, Q61E, C67Y, H69K  
5210 2006_ZA_5210B None    T12S, I15V, L19T, M36I, R41K, L63P, H69K  
  2009_ZA_5210F LPV 108   T12S, I15V, L19T, M36I, R41K, L63P, H69K  
5228 2007_ZA_5228B None    T12S, L19I, M36I, N37S, R41K, L63S, H69K, V82I  
  2007_ZA_5228F RTV 22   T12S, L19I, M36I, N37S, R41K, L63S, H69K, V82I  
5242 2007_ZA_5242B None    T12S, I15V, L19V, K20R, E35D, M36I, R41K, R57K, D60E, Q61E, L63P, H69K  
  2007_ZA_5242F RTV 13 V82A  T12S, I15V, L19V, K20R, E35D, M36I, R41K, R57K, D60E, Q61E, L63P, H69K  
5245 2007_ZA_5245B None    T12S, I15V, L19I, E35D, M36I, R41K, L63V, H69K, T74S  
  2007_ZA_5245F RTV 13   T12S, I15V, L19I, E35D, M36I, R41K, L63V, H69K, T74S  
5251 2007_ZA_5251B None    L19I, N37S, R41K, L63P, H69K, V77I  
  2008_ZA_5251F RTV 38 I54V, V82A  L19I, N37S, R41K, L63P, H69K, V77I