Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Pessoa (2015)
Title Enhanced detection of viral diversity using partial and near full-length genomes of human immunodeficiency virus Type 1 provirus deep sequencing data from recently infected donors at four blood centers in Brazil.
Citation Transfusion
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 43
NumPts 43
Subtype B, F, CRF70_BF, C, B + F, CRF47_BF, CRF45_cpx


Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
10BR_MG007 MG007 None None   K11Q, V35I, S48T, K122E, D123N, I135V, S162C, Q174R, R211K, A272P, K275R, K277R, I293V, I326V, Q334L, M357T, A360T, T377M, A400T, T403M, V435A, N447S, V458I, S468P, T470A, V559I  
10BR_MG010 MG010 None None   E6D, V35T, E40D, K49R, V60I, D123E, I135T, I142V, E169D, K173T, Q174K, V179T, T200A, Q207K, R211Q, V245Q, E248D, A272P, T286A, E291D, I293V, E297T, I329L, F346L, R356K, G359S, T377Q, K390R, Q394L, E399D, A400T, K431T, V435A, A446S, E449D, L452K, V466A, D471E, T477A, H483Q, L491S, E492K, I506L, L517I, S519N, K527N, A534S, A554T  
10BR_MG017_1 MG017_1 None None   K20R, V21I, V35I, T39A, D123E, I135L, S162C, E169D, K173A, Q174E, D177E, T200A, Q207E, R211K, F214L, V245Q, A272P, E291D, I293V, E297T  
10BR_MG017_2 MG017_2 None None   V365I, T377L, K390R, Q394L, A400T, K431T, V435A, A446S, E449D, D471E, T477A, H483Q, E514D, S519N, Q524E, V531I, A534S, A554T, I556V, K558R  
10BR_MG029 MG029 None None   K122E, I135K, N175H, V179I, G196E, T200I, V245E, K277R, E297K, M357T, T369A, A376V, K390R, A400T, L452S, V467I, S468H, H483Y, L491S, I495M, Q524E, A554AS, V559VI  
10BR_MG034 MG034 None None   K49R, I50V, K101R, I135T, R211K, V245E, K277R, E291D, V292I, I293V, E297T, I326V, P345Q, A355G, M357I, T377M, K390R, K395R, T403I, S468P, G490E, A554S  
10BR_MG035 MG035 None None  V179D K20R, K102Q, K122E, I135T, T200A, I202V, R211T, F214L, V245E, A272P, I293V, E297Q, P313T, V317A, G333E, Q334M, R358K, K366R, T377S, T386I, K390R, T403M, V435E, N447H, S468P  
10BR_PE001 PE001 None None   V35I, R83K, D123E, I135R, I202V, R211K, A272P, V276I, I293V, E297K, D324E, I329L, Q334H, R356K, A360T, A376T, A400T, K451R, D460S, R461K, V467I, Q509I, Q524E, A554T  
10BR_PE010 PE010 None None   E6D, D123E, I178M, T200A, E204N, R211K, V245K, K277R, T286A, I293V, E297K, Q334E, M357K, S379G, T386I, K390R, A400T, K431T, V435A, S468P, Q547K, A554T  
10BR_PE018 PE018 None None   K173E, N175H, T200A, Q207E, V245Q, D250N, A272P, K277R, E291D, I293V, P294S, E297D, P313S, G333E, R356K, M357I, G359T, K366R, T377Q, K390R, K395R, E399D, E404D, L452M, K465R, V466I, S468A, D471E, H483Q, L491S, S519N, V531I, A534S, E546K, D549N, A554N E302K, E449K, G504K, G541E, G555E 
10BR_PE029 PE029 None None   K20R, V35I, K49R, A158S, K173A, T200A, Q207E, V245Q, A272P, V292I, I293V, Q334E, R356K, R358K, G359S, K366R, T369A, A376T, K385R, K390R, W398X, E399D, A400T, W401*, W402*, W406*, W414*, E430K, E432K, R448K, L452S, S468P, H483Y, E492K, V559I F346W, A371S, E404K, E413K, G436R, G444K, G456R, G462R, E478K, G490R, W535K, G543R, G544R, G555K 
10BR_PE034 PE034 None None   K102Q, I135T, S162A, Q174N, D177E, Q207R, F214L, V245K, A272P, K277R, R284K, I293V, E297V, I329L, A360T, A376C, T377L, K390R, A400T, T403A, V435I, R448K, E449G, L452A, L469F, H483C, Q487H, L491S  
10BR_PE056 PE056 None None M184I E138K, G190R W71*, W88*, K102Q, I142V, W153*, T165I, E169K, R172K, E194K, G196R, T200A, R211K, W212*, W229*, M230I, W239*, V245T, E248D, W252*, W266*, V276I, R284K, I293V, T296S, E297A, R307K, E308K, S322T, P345T, R358K, G359S, A376T, W383*, T386I, K390R, W398*, A400T, W401*, W402*, T403I, W410*, W414*, E430K, E432D, V435P, R448K, V467I, S468P, A534S, W535*, D549N, A554T E29K, M41I, G45K, G51R, E53K, G99R, G141E, R143K, G152R, G155R, G213R, G231S, G262R, G273E, G285R, G316R, G384K, E404K, G444K, G453K, E478K, G504R, E523K, G541R, G544S, G555K 
10BR_PE091 PE091 None None   E6D, S68G, D123E, I142A, S162A, D177E, I178L, V179I, E204N, Q207D, R211K, F214L, V245Q, A272P, A288S, E297K, K311R, E344D, K390R, E399D, A400T, V435S, L452I, S468P, Q480H, H483Y, Q487L, G490N, A554T  
10BR_PE097 PE097 None None   V35I, V60I, R83K, I135T, T165I, I178L, Q197E, Q207E, A272P, K277R, I293V, E297K, I329L, F346Y, K366R, T369A, A376T, E399D, A400T, D460N, I506L, Q524E, A534T, V548I, A554N  
10BR_PE098 PE098 None None   V35E, V118I, I135T, T165I, R211K, F214L, V245M, A272P, I293V, E297T, Q334L, A360T, V372L, T386I, A400V, H483N, A554T  
10BR_PE100 PE100 None None D67G, M184V, T215S, K219Q K101E, G190C E6K, V35I, K46Q, S68G, K102R, V106I, K122E, I135K, V179T, Q207K, R211S, H221Y, V245Q, R284K, A288S, I293V, E297A, V317A, S322T, Q334L, M357V, T369A, S379G, T386I, A400T, E404D, V466A, L469I, L491S, K512H, S519N, Q524E  
10BR_RJ015 RJ015 None None   V35T, T39L, D123E, I135T, S162C, E169D, K173T, T200A, I202V, Q207K, R211S, V245Q, A272P, K277R, T286A, E291D, I293V, E297T, A304E, V317A, I329L, R356K, G359S, I375V, A376S, T377L, T386I, K390R, Q394L, E399D, A400T, K431T, A446S, E449G, L452E, V466A, S468F, D471E, T477A, Q480E, H483Q, L491S, S519N, A534S, V559I  
10BR_RJ023 RJ023 None None   K104R, K122E, I142V, S162C, E169D, K173A, Q174K, T200R, Q207E, R211K, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297T, K311R, G333E, Q334H, R356K, G359S, T377L, K390R, Q394L, E399D, A400T, K431T, V435A, A446S, L452K, V466A, D471E, T477A, Q480A, H483Q, G490E, L491S, L517I, S519N, K527N, E529K, A534S, V559I D443N, G444E, G456E 
10BR_RJ026 RJ026 None None   A98S, D121C, K122E, D123G, I180V, T200A, R211K, D237N, V245M, A272P, K277R, K281R, T286A, E291D, V292I, I293V, E297K, M357T, K366R, A376T, A400T, V435I, D460N, R461K, H483L, S519N, K527N, A534S  
10BR_RJ032 RJ032 None None   D123E, I135T, G196E, Q197K, I293V, G333D, Q334H, G359S, K366R, T386I, T403M, V435VA, S468P, H483N, K512R  
10BR_RJ041 RJ041 None None   V35T, K104R, I135T, E138A, S162C, G196E, Q197K, V245I, A272P, K277R, Q278H, I293V, E297A, K347R, K366R, A376S, T386I, K388R, K390R, T403M, S468P, H483Y, K527N, A554N  
10BR_RJ046 RJ046 None None  V108I V35S, K49R, K122E, D123E, E138A, S162C, K173T, Q174K, D177E, R211K, V245Q, D250E, A272P, K275R, T286A, V292I, I293V, P294T, E297T, V317L, E328D, Q334R, R356K, M357V, G359S, T377Q, Q394L, A400T, K431T, V435A, A446S, E449D, L452I, L469M, D471E, T477A, H483Q, L517I, A534T, A554S  
10BR_RJ050 RJ050 None None   I135T, S162C, N175H, V245I, A272P, V292I, I293V, E297A, Q334L, G335S, T338S, M357T, T369A, K374R, I375V, T377A, T386I, K390R, A400T, V435A, F440Y, L452I, V467I, S468T, L491S, L517V, V531I  
10BR_RJ051 RJ051 None None   T403M, V435A, S468P, H483N, K512R  
10BR_RJ053 RJ053 None None   V35T, T39A, E40D, V106I, V118I, K122E, I135T, E138A, S162C, E169D, R172K, K173T, Q174K, I202V, E203K, Q207E, L210M, F214L, E248Q, A272P, K277R, T286A, E291D, V292I, I293V, E297T, P313Q, V317A, K366R, K390R, Q394L, E399D, A400T, K431T, V435A, A446S, L452K, D471E, T477A, H483Q, L491S, L517V, Q520L, K527Q, A534S, K550R, A554T  
10BR_RJ054 RJ054 None None   V35L, K102Q, D121H, K122E, I142L, D177E, I178M, T200A, V245E, A272P, K277R, T286A, I293V, E297K, Q334E, I341F, A360T, K374R, T377M, T386I, E399K, T403M, V435L, S468H, H483Y, V493A, A554S H208Q 
10BR_SP003 SP003 None None   V60I, D121H, K122E, I135T, I142V, K166R, I178L, R211K, V245M, A272P, V276I, G333E, Q334N, T386I, V435M, L469I, T470M, H483L, T497A, V531I, A554S  
10BR_SP009 SP009 None None M184I G190R S162T, E169D, Q174K, G196R, R211K, W212*, F214L, W229*, M230I, W239*, V245M, W252*, W266*, A272P, K277R, I293V, E297A, E298K, R307K, G333E, Q334L, W337*, R356K, R358K, A376T, W383*, T386I, W398*, W401*, T403R, W406*, W410*, W414*, E415K, W426*, E430K, R448K, S468P, H483Y, L517V, E529D, W535*, E546K, R557K G231S, G262R, G273K, G285R, G316R, E344K, G384R, E413K, G436R, G444K, G453R, G456R, G462R, E478K, G504R, G541R, G543R, G544R, G555R 
10BR_SP011 SP011 None None M184I G190R E28A, V35T, E40D, V60I, K102Q, D121H, K122E, I135T, S162A, E169D, Q174K, D177E, E194K, R211K, F214L, M230I, V245Q, E248T, G273R, K275Q, K277R, T286A, E291D, V292I, I293V, V317A, S322T, G333R, I341V, F346Y, M357I, R358K, G359S, K366R, T377Q, K390R, A400T, T403S, K431T, L452K, R461K, D471E, T477A, Q480E, H483Y, L484I, Q487K, L491S, E492K, Q509K, E516D, K527Q, E529D, K530Q, V531I, A534S, A554S G15R, G51R, E53K, G93R, G99R, G262R, R307Q, G316R, W383Q, G462R, G504R, G541R 
10BR_SP014 SP014 None None   K20R, K101R, K102Q, K166R, K173R, R211K, Y232YH, V241VL, V245K, K277R, T286A, I293V, E297K, Q334E, M357K, S379G, T386I, K390R, A400T, K431T, V435A, S468P, Q547K, A554T  
10BR_SP017 SP017 None None  K103N K20R, V35I, K64R, A98S, I135T, K173R, G196E, R211K, V245T, E248D, V276I, K277R, K281R, I293V, P294PT, E297K, K311KR, V317VG, S322T, K366R, A376T, T377Q, T386V, K390R, A400T, T403V, H483Y, E514D, L517I, Q524K, K527N, Q547K, A554T F77C 
10BR_SP021 SP021 None None   G15GE, K49R, D121Y, K122E, I135T, K166Q, E169D, D177E, I195V, G196E, T200A, E248D, I257L, A272P, K277R, I293V, E297G, Q334Y, T338S, A376T, T386I, T403I, S468P, H483Y, S519N, K527N, K530R, V559I  
10BR_SP038 SP038 None None V75M  V90I, D123E, I135T, R172K, D177E, R211G, T286A, E291D, I293V, S322T, I329L, Q334N, T377S, T386I, E399D, A400T, T403I, E449D, S468P, S519N, A554K  
10BR_SP042 SP042 None None  K103N, P225H V35T, S68G, K122E, K173A, Q174K, I178M, I195L, T200A, Q207R, L210F, R211K, I244V, V245K, K259R, A272P, K277R, T286A, E297K, G333E, G335C, K366R, V381I, K390R, T403M, L452A, K465N, Q487K, L491S, A534S  
10BR_SP043 SP043 None None   K43N, K64R, K102Q, V118I, K122E, D123N, S162A, D177G, R211G, F214L, E248D, A272P, T286A, V292I, E297A, Q334L, R356K, M357I, R358K, T377Q, K390R, I393M, A400S, V417I, V435L, L452I, R461K, V467I, H483Q, Q524L, A554N, K558R  
10BR_SP045 SP045 None None   V245M, A272P, K277R, I293V, E297K, A360T, K366R, A376T, T386I, E399D, A400T, T403M, V435L, L452K, S468P, S519N, Q524K, K527Q  
10BR_SP046 SP046 None None   V35I, S68G, D123G, A158S, S162A, K173I, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, V317A, R356K, G359T, K366R, T377L, Q394L, E399D, A400T, K431T, V435A, A446S, L452T, K454R, D471E, T477A, H483Q, L491S, S519N, K527G, V531I, A534S, V559I  
10BR_SP048 SP048 None None   K11N, V35T, T39I, D123E, I135V, E138A, I142T, E169D, R172K, K173A, Q174K, I180V, Q207E, F214L, A272P, K277R, A288S, E297T, Q334D, M357T, I375V, K385R, E399D, A400I, V435I, A446S, T450N, L452K, V466A, S468P, T470S, D471E, T477A, H483Q, L491S, S519N, A534S, A554T, V559I  
10BR_SP049 SP049 None None  Y188L V35I, A98S, K122E, D123E, T139A, A158S, D177E, V179I, G196E, R211G, V245N, D250E, I293V, E297A, Q334L, M357T, K374R, A376S, T386I, K390R, A400T, E413D, V435L, N447S, E449D, V466I, V467I, K512Q, L517I, S519N, V548I, A554S  
10BR_SP050 SP050 None None   K20R, V60I, K122E, I135T, E169D, F214L, V245E, A272P, V276I, I293V, V317A, M357T, K366R, T377S, V381I, T386I, I393M, A400T, T403I, V435I, L452A, S468P, L517I, Q524E, K530R, A554T  
10BR_SP055 SP055 None None M41L, T215D K103N, K238T E40D, K43R, K122E, I135T, S162C, D177E, I178L, I195L, V245T, A272P, K281R, I293V, Q334S, M357T, R358K, E370G, T386I, A400T, R461K, S468T, T470M, G490E, K512T, A554N N137S 
10BR_SP057 SP057 None None   E6D, K20R, V35T, T39R, K103R, V118I, D123E, T165I, G196K, T200A, I202V, R211K, F214L, V245M, A272P, K277R, T286A, V292I, I293V, E297A, L310I, V314I, D324E, Y339F, V365I, A376S, T386I, K390R, A400T, S468P, T470V, H483Y, A554S, I556V K32L