Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Charpentier (2014)
Title Genotypic resistance profiles of HIV-2-treated patients in West Africa.
Citation AIDS
SelectedGene RT
SelectedSpecies HIV2
SelectedType Clinical
NumIsolates 25
NumPts 25
Host Human

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
001TS 001TS_RT RTI RTI M184V, S215Y Y227L M11E, L21I, T27S, K40R, T58S, K102E, E122P, D123N, V135T, A138S, H162Y, E169D, A174T, K176S, I179T, G211N, L212M, D218E, H228Q, I251V, Y271F, K277R, L279I I8V, I10V, E32L, K35N, K82T, I90V, H121D, P126K, T163S, Q166K, T194S, L203S, T237K, Q248E, A267T 
004CP 004CP_RT RTI RTI Q151M, M184V I181V E6Q, M11T, D123E, P126Q, H162Y, I180L, F214L, H228K, E334D, E344G V2I, K4E, I10V, R22K, V167I, K176P, E207Q, L270I, H317C 
006CP 006CP_RT RTI RTI M184I  K102E, L109I, E122P, P126Q, H162Y, E169D, K176S, R200K, G211D, L212M, D218E, H228R, I251V, Y271F, L279I, R307K, S311E, H317S, E322G, E324P, E334A, T338S, E344G I90V, I118V, H121D, Q166K, L203S, Y227F, T237K, Q248E, R281K, L303F, E304Q, Q320K, K323V, D332N, Q333L, E345D 
017CP 017CP_RT RTI RTI M184V, S215Y, E219D  L21I, T27S, E32Q, K40KR, T58S, K102S, T107S, E122P, P126Q, H162Y, M164L, R165A, E169D, I179T, R200K, G211N, D218E, Y227I, H228K, I251V, Y271F, K277R, L279I, S311E, H317S, E322G, E324P, E334A, E344G K4R, I8IV, I10V, M11K, G15DE, I90V, H121D, T163S, Q166K, V167I, T194S, L203S, L212I, T237K, Q248E, R281K, E304Q, I308T, Q320K, K323IV, D332N, Q333L, E345D 
018CP 018CP_RT RTI RTI M184V  L21I, T27S, K66R, K102E, K103R, E122P, P126Q, H162Y, E169D, I179T, G211D, H228K V5I, I8V, I10V, M11K, E32L, I90V, I118V, H121D, S134A, E139G, R165G, Q166K, K176G, T194S, E207Q, L212I, Y227F, T237K, Q248E 
019CP 019CP_RT RTI RTI M184V I181V L21I, T27S, K66R, K102E, E122P, P126Q, A138T, H162Y, E169D, I179T, G211S, D218E, H228K V5I, I8V, I10V, M11K, E32L, I90V, I118V, H121D, T163S, Q166K, K176N, I189V, T194S, L212V, Y227F, T237K, Q248E, I251S 
021CP 021CP_RT RTI RTI M184V, S215Y  M11Q, L21I, T27S, K35R, K40R, K102E, K103R, E122P, D123N, P126Q, H162Y, K176S, I179T, L212M, H228Q, L246I, K249R, I251V, Y271F, K277R, H278N, L279I, R284K, L303M, R307K, H317S, E322G, E324P, E334A, E344G, K347R V2M, V5I, I8V, I10V, E32L, R78RK, E79EK, H121D, T163S, Q166K, I189V, T194S, L203S, Y227F, T237K, Q248E, R281K, K286R, M287L, S311G, Q320K, K323V, D332N, Q333L, E345N 
043TS 043TS_RT RTI RTI   L21I, T27S, D86EG, K102E, E122P, P126Q, R165L, E169D, R172K, K176S, I179T, G211D, H228Q, I251R, Y271F, K277R, L279I, R307K, S311E, H317S, E322G, E324P V5I, I8V, I10V, M11K, E32L, T60V, I75V, V83A, I118V, H121D, T163S, Q166K, I189V, T194S, L203S, N210H, L212I, Y227F, T237K, Q248E, A268S, P272M, R281K, E304Q, Q320K, K323V, D332N 
103CP 103CP_RT RTI RTI   M11T, R125K, P126Q, V135T, I180L, H228Q, R307K, E334D V2I, V5I, I10V, R22K, E49V, V167I, K176P, L270I, H317C, Q330I 
106CP 106CP_RT RTI RTI M184V I181V K64R, K102E, T107S, L109I, E122P, P126Q, V135T, A138S, H162Y, R200K, G211N, L212M, D218E, Y227I, H228R, I251V, Y271F, L279I, R307K, S311E, H317S, E322G, E324P, E334A, E344G, K347R I63V, I90V, H121D, T163S, Q166K, K176E, T194S, L203Y, E207Q, T237K, Q248E, A268S, R281K, E304Q, Q320K, K323V, D332N, Q333L, E345D 
108CP 108CP_RT RTI RTI M184V, E219D I181V M11X, L21I, T27S, K40R, K102E, K103R, E122P, D123E, P126Q, A138T, H162Y, E169D, P170PS, I179T, G211D, L212M, S215X, D218E, H228K, K249R, I251R, Y271F, K277R, L279I, R284K, R307K, S311E, H317S, E322G, E324P, E334A, E344G, K347R V5I, I8V, I10V, E32L, I90V, I118V, H121D, T163S, Q166K, K176E, I189V, T194S, Y227F, T237K, Q248E, L303F, E304Q, Q320K, K323I, D332N, Q333L, E345N 
CB017 CB017_RT RTI RTI M184V  M11T, L109V, V111I, D123E, P126Q, H162Y, I180L, D195X, R200K, H228R, I251V V5I, I10V, R22K, P51S, R104K, T163S, V167I, K176P, Y227F, L270I 
CB024 CB024_RT RTI RTI  I181V, Y227L M11E, L21I, T27S, K28R, K35R, K66R, T84X, K102R, T107S, E122P, D123DN, P126Q, V135T, H162Y, E169D, K176S, I179T, G211D, L212M, D218E, H228K, I251V, Y271F, K277R, L279I V5I, I8IV, I10V, E32L, V83Y, I90V, H121D, T163S, Q166K, T194S, L203S, T237K, Q248E, R281K 
CB035 CB035_RT RTI RTI I75IM, Q151M, M184V, S215F I181V L21I, T27S, K40KR, K102E, K103R, E122P, D123E, P126Q, A138T, H162Y, E169D, K176S, I179T, R200K, G211N, D218E, H228K, Y271F, K277R, L279I, R284K, R307K, S311E, H317S, E322G, E324P, E334A I8V, I10V, M11K, E32L, V83VA, I90V, I118V, H121D, Q166K, I189V, T194S, L212I, D224E, Y227F, T237K, Q248E, I251K, L303F, E304Q, Q320K, K323I, V329I, D332N, Q333L 
CB043 CB043_RT RTI RTI M184I  M11T, K20R, E39D, P126Q, H162Y, T163TI, I180L, H228Q, I244L, I251R, R307K V5I, I10V, R22K, D76E, R78RK, N81T, R104K, A138M, K176P, D195G, Y227F, L270I, H317Y, E324D 
CB052 CB052_RT RTI RTI Q151M, M184V  E6K, M11T, E32D, D86E, R125K, P126Q, V135T, I145IM, H162Y, I180L, Y227I, H228Q, I251V, E334D V2I, I10V, R22K, H121D, E122EK, V167I, K176P, L270I, R281K, H317C, Q330L 
CB063 CB063_RT RTI RTI M184V I181V L21I, T27S, K66R, K102E, K103R, E122P, D123E, A138T, R165X, I179T, R200K, G211D, L212M, D218E, H228K, K238R, I251V, Y271F, R307K, S311E, H317S, E322G, E324P, E334A, E344G, K347R I8V, I10V, M11K, E32L, I90V, H121D, T163S, Q166K, K176D, I189V, T194S, L203F, E207Q, Y227F, T237K, Q248E, A268S, R281K, Q320K, K323V, D332N, Q333L, E345N 
CB069 CB069_RT RTI RTI K70N, M184V  L21I, T27S, K43R, K102E, K103R, E122P, P126Q, H162Y, E169D, I179T, G211D, L212M, D218E, H228K, K249R, I251X, Y271F, K277R, L279I V5I, I8V, K9R, I10V, M11K, E32L, I90V, H121DN, T163S, Q166K, K176N, I189V, T194S, Y227F, T237K, Q248E, A268S 
MI004 MI004_RT RTI RTI M184V V108I M11T, K20R, E39G, T58S, K64R, K82R, P126Q, I180L, R200K, H228Q, E250EK, E334D, T338A, E344G I10V, R22K, R78RK, R104RK, Y146YC, T163M, V167I, K176P, V178VI, Y227F, L270I, D332S 
MI006 MI006_RT RTI RTI K65R, K70KR, Q151M, M184V  M11T, K35R, K64R, V111I, P126Q, H162Y, I180L, R200K, K223KR, Y227I, H228Q, T237TN, I244L V5I, I10V, R22K, R104K, K176P, D195G, V263I, L270I 
MI015 MI015_RT RTI RTI Q151M  P1L, V2L, E32D, K35KR, V111I, D123G, P126Q, V135T, H162Y, R172RK, A174AT, F214L, D218E, H228Q K9E, I10V, M11K, Q91QR, V167I, K176P 
MI018 MI018_RT RTI RTI D67N, K70N, Y115F, M184V I181V L21I, T27S, K35R, E44D, K102E, E122P, P126Q, H162Y, E169D, K176X, I179T, R200K, G211N, L212M, D218E, F221L, H228K V5I, I8V, I10V, M11K, E32L, I90V, I118V, H121D, T163S, Q166K, I189V, T194S, Y227F, T237K 
US014 US014_RT RTI RTI K65R, D67DN  M11T, V111X, P126Q, H162Y, I180L, R200K, H228Q, I244L V5I, I10V, R22K, N69T, I75V, R104K, K176P, D195G, Y227F, I251K, L270I 
US025 US025_RT RTI RTI   L21I, T27S, K28KR, K102E, T107S, E122P, P126Q, V135T, A138S, H162HY, E169D, K176S, G211N, L212M, D218E, Y227I, H228K, I251V V5I, I8V, I10V, M11K, E32L, P51S, I90V, I118V, H121D, R165S, Q166K, T194S, L203S, T237K, Q248E 
US068 US068_RT RTI RTI A62V, K65R, M184V, E219D I181V L21I, T27S, K35R, K64KR, N69NS, K102E, K103R, E122P, P126Q, A138T, H162Y, R165A, E169D, K176S, I179T, G211S, D218E, H228K, I251T, Y271F, K277R, L279I, T296S, R307K K4R, V5I, I8V, I10V, M11K, E32L, I90V, I118V, H121D, T163S, Q166K, I189V, T194S, L212I, Y227F, T237K, Q248E, R281K, L303Y, E304Q