<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Cuevas (2010)
Title Biological and genetic characterization of HIV type 1 subtype B and nonsubtype B transmitted viruses: usefulness for vaccine candidate assessment.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 39
NumPts 39
Subtype B, G, C, CRF02_AG, A, D, B + F, CRF24_BG

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
ESX1589-2 ESX1589-2 Unknown Unknown  V179E V35T, K43R, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, V189I, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329V, Q334L, F346Y, R356K, M357R, R358G, G359S, Q367E, A371V, Q394R, A400V, E413D, K431T, V435A, F440Y, R461K, R463K, V467I, S468T, D471E, T477A, H483Q, L491S, K512R, L517V, S519N, A534S, A554S  
ESX1608-8 ESX1608-8 Unknown Unknown   V35T, E40D, V60I, K122E, D123S, I135T, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, V245E, D250E, T286A, E291D, I293V, P294T, E312D, G335D, Y342F, R356K, M357K, R358G, G359S, K366R, T369A, E370N, A371V, I375V, A376V, T377M, K390R, A400T, T403M, E404D, E432D, V435A, T470A, D471E, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554S  
ESX1628-2 ESX1628-2 Unknown Unknown   V35T, V60I, A98S, K122E, D123S, I135RT, K173A, Q174K, D177E, I195L, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, P294Q, E297T, D324E, I329V, Q334L, F346Y, R356K, M357R, R358G, G359S, K366R, Q367E, A376S, Q394R, A400V, E413D, Q428KR, K431T, V435A, F440Y, N447S, L452I, R463K, V466I, V467I, S468T, H483Q, L491AS, L517I, S519N, K527N, A534S, A554S  
ESX1702-3 ESX1702-3 Unknown Unknown   V35T, E36A, T39D, S48T, V60I, K122E, D123S, I135T, K173A, T200A, Q207K, R211T, K238R, V245Q, E248D, A272P, K277S, T286A, E291D, V292I, I293V, G335D, R356K, M357L, G359T, T362TS, V365I, K366R, T377R, I380L, K390R, E404D, N447S, L452K, R461K, V466I, D471E, T477A, H483Q, L491S, L517I, S519T, K530R, A534S, A554S  
ESX230-10 ESX230-10 Unknown Unknown D67A, K70A, L74V, M184I, T215V K103N, P225H K20R, V35T, E36D, T39S, T69S, D123E, S162A, K173T, Q174K, T200A, R211K, V245K, A272P, T286A, E291D, I293V, P294T, S322T, I326V, G335D, M357K, G359S, K366R, T369V, A371V, I375V, A376V, T386A, K390R, K395R, T403R, E432D, V435A, S468P, D471E, K476Q, Q480H, L491A, K512R, L517I, S519N, Q524K, K527E, K530R, A534S, A554N P9K 
ESX772-8 ESX772-8 Unknown Unknown   V35T, E36D, T39I, K43R, V60I, A98S, K122E, D123S, I135T, E138A, K173T, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297T, D320E, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371L, Q394R, A400V, E413D, Q428R, K431T, V435A, F440Y, R461K, R463K, V466I, V467I, S468T, D471E, T477A, I482V, H483Q, A502V, K512R, L517I, S519N, A534S, A554S  
ESX963-4 ESX963-4 Unknown Unknown D67N, K70R K101E, G190A K20R, V35I, M41MV, T69N, K122E, D123S, I135T, K166R, D177E, I178M, Q207E, R211K, L228Q, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, P294S, E297A, S322A, I329V, G333E, Q334H, T362S, T386I, K390R, A400T, T403M, V435L, S468T, T470N, D471N, H483K, I495V, Q524L, K527N, A554N, K558R G45GR 
ES_P1261 ES_P1261 None None   P4S, V35T, E36D, D123E, S134SR, I135V, S162A, K173I, Q174K, D177E, T200A, Q207S, R211K, F214L, V245Q, V276I, L283I, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357R, G359S, A371V, K390R, A400T, T403M, E413D, E432D, D471E, T477A, H483Y, L491S, K512R, S519N, Q524K, K527G, E529D, V531I, A534S, A554S  
ES_P1423 ES_P1423 None None   T7TA, K32KE, V35T, E36D, E40D, K49R, P52PA, K122E, D123E, V148VG, S162A, E169EK, K173T, Q174K, D177E, G196E, Q197K, T200A, Q207G, R211K, V245Q, E248D, T286A, E291D, I293V, S322A, I326V, G335D, R356K, M357K, G359S, T369V, A371V, I375V, A376V, K388R, K390R, E396X, T403M, E432D, T450S, V467VI, D471E, Q480H, H483Y, L491S, K512R, E514D, S519N, Q520L, Q524E, E529D, A534S, A554T K13KT, Q23R, F61FV 
ES_P1981-2 ES_P1981-2 None None   V35T, K43R, V60I, A98S, K122E, I135T, K173I, Q174K, D177E, T200A, R211S, V245Q, E248D, D250E, S251N, A272P, T286A, A288G, E291D, V292I, I293V, E297T, D320E, D324E, I329V, Q334P, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, T377I, Q394R, A400T, E413D, K431T, V435A, F440Y, R463K, V466I, V467I, S468T, D471E, T477A, H483Q, L484I, K512R, S519N, A534S, A554K  
ES_P2008 ES_P2008 None None   K32R, R83K, R211S, P243A, V245K, A288S, I293V, I375V, V381I, T386I, E399N, A400L, V435I, V458I, H483N, L491V, E516D, S519N, K530R  
ES_P2021-3 ES_P2021-3 None None  V108I V35I, R83K, E169EK, R172RK, G196E, T200I, E204D, V245M, A272P, P294S, S322T, R358K, A376T, E399D, A400T, V435A, E449D, T450S, D460N, R461K, D471N, H483N, Q547K P119L, R211L 
ES_P962 ES_P962 None None K70KN  V35T, E40D, K49R, V60I, D123N, K173T, Q174N, D177E, T200A, Q207E, R211K, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, I329V, Q334S, G335D, F346Y, R356K, M357R, R358G, G359S, T386V, Q394R, A400V, Q428R, K431T, V435P, F440Y, R461K, R463K, V466I, V467I, S468T, L469I, T470Q, D471E, Q480H, H483Q, L491S, K512R, S519N, A534T, Q547K, A554S  
ES_X1870 ES_X1870 None None   V21I, V35I, K43R, V60I, A98S, K122E, D123S, K173R, Q174K, D177E, I178M, T200A, Q207K, R211N, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297V, D320E, D324E, I329V, Q334P, G335D, F346H, R356K, M357R, R358G, G359S, A371V, V381VI, K390R, Q394R, A400V, E413D, K431T, F440Y, D460N, R461K, R463K, V466I, V467I, S468T, D471E, T477A, H483Q, L484I, L491S, K512R, S519N, A554S  
ES_X1890 ES_X1890 None None   E169D, V245M, D250E, T286A, K311R, Q334L, M357T, A376T, K390R, Q394P, A400T, E432D, K454R, K530R, A554S, K558R V466VG 
ES_X1936 ES_X1936 None None   V35T, E36A, T39D, S48T, V60I, K122E, D123S, A158S, K173A, T200A, Q207K, R211T, K238R, V245Q, E248D, A272P, K277S, T286A, E291D, V292I, I293V, G335D, R356K, M357L, G359T, V365I, K366R, I375V, T377R, K390R, E404D, N447S, L452K, R461K, V466I, D471E, T477A, H483Q, L491S, L517I, S519T, K530R, A534S, A554S  
ES_X1958 ES_X1958 None None M41L, L210W, T215S  E44D, V60I, S68G, K122E, V148VG, S162SN, R211K, S251I, K277R, T286A, I293V, P294Q, Q334D, M357T, E399D, A400L, V435I, K451R, D460N, R461K, L469I, L491S, K512R  
ES_X1959 ES_X1959 None None  K103KN V35M, A98AS, K122E, K277KR, Q278QH, T286A, I293V, I326V, E328D, M357T, V365I, A376S, K390R, A400T, N418S, R461K, I482V, L491P, A502T, Q524K, K527Q  
ES_X1998 ES_X1998 None None   V60I, K122E, I135T, E138A, I142V, S162C, G196E, A272P, T286A, I293V, P294S, A360T, K366R, R461K, Q509E, K512T, S519N, K558R  
ES_X2102 ES_X2102 None None   K49R, D121H, K122E, I135T, D177E, I202V, R211K, K277R, T286A, K287R, A288T, T296S, E297A, S322T, I326V, A376S, T386I, T403M, S468P, Q509T, E516EK, Q524QH, A554T, V559I D443DN 
ES_X2110 ES_X2110 None None   V35T, E40D, K49R, V60I, K173L, Q174K, D177E, V179I, T200A, Q207A, R211S, A272P, I274V, E291D, V292I, I293V, P294T, L295M, A327V, G335D, M357K, G359S, K366R, T369A, A371V, I375V, A376V, T377M, T386A, A400T, T403M, E404D, E432D, V435A, D471E, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527G, E529D, A534S, A554S, V559I  
ES_X2118-2 ES_X2118-2 None None   V35T, E36A, T39E, S48T, I50V, K122E, D123S, S162C, K166R, K173A, D177E, T200A, Q207E, V245Q, D250N, A272P, K275Q, T286A, E291D, V292I, I293V, S322A, Q334H, R356K, G359T, T377M, S379C, K390R, Q394L, E399D, A400T, E404D, E449ED, L452I, V466I, S468T, T470N, D471E, L491H, S519N, K530R, A534S, A554S  
ES_X2149 ES_X2149 None None   K20R, K122E, I135T, R211K, F214L, T286A, A288S, E297K, Q334N, G335D, R356K, K385R, K390R, A400T, T403A, F416Y, D460N, R463K, H483Y, L491S, A508S, S519N, V531I, A554T  
ES_X2210-3 ES_X2210-3 None None   E6D, V21I, I135T, S162Y, R211K, I293V, E297K, V317A, D324E, Q334A, F346C, G359S, A360T, S379G, K390R, V435A, S468T, I482V, A502V  
ES_X2231 ES_X2231 None None  K103N V35I, R83K, D123E, D177E, V179I, T200I, I202V, R211K, A272P, V276I, K277R, L283I, V292I, I293V, Q334E, T369A, A376T, K390R, E399D, A400T, K451R, D460N, R461K, K465R, Q480H, I506L, A508S, K512R, E516D, S519N  
ES_X2363-2 ES_X2363-2 None None   V35T, E36A, T39E, K122E, D123N, A158S, S162A, E169D, K173A, Q174K, D177E, T200A, Q207N, R211K, P243A, V245K, A272P, K277R, E291D, V292I, I293V, Q334E, R356K, M357R, R358K, G359A, A376S, T377M, K390R, E399D, A400T, E404D, V435I, K454R, V466I, S468T, D471E, H483Q, L491P, Q507H, S519N, Q524K, K527N, K530R, A534S, A554K  
ES_X2400-3 ES_X2400-3 None None  K103N V35I, R83K, D123E, D177E, V179I, T200I, R211K, A272P, V276I, K277R, L283I, V292I, I293V, Q334E, A376P, V381I, K388KN, K390R, E399D, A400T, K451R, D460N, R461K, K465R, Q480H, I506L, A508S, K512R, S519N  
ES_X2425-2 ES_X2425-2 None None   A98S, K102Q, D123E, I135V, S162C, Q174G, D177E, R211K, A272P, K277R, K281R, I293V, Q334D, M357T, I375V, A376S, S379C, L452S, S468P, T470A, H483Y, S519N, V531I W229W* 
ES_X2456-2 ES_X2456-2 None None   A98S, I135L, S162C, E169EK, D177E, I178L, T200A, R211K, L228Q, D250E, I257L, A272P, K277R, T286A, I293V, E297T, I329L, K350R, R358K, G359N, T377Q, T386I, K390R, T403M, Y405H, E449D, L517V, A554S  
ES_X2510-2 ES_X2510-2 None None   V10VI, D123E, I142V, I178M, Q207R, K277R, E297A, I326V, I329L, R358K, V365I, T386I, E399D, T403M, V435I, R461K, V466I, A554T  
ES_X2515-3 ES_X2515-3 None None   A98S, D123E, E169K, R172K, D177E, I178V, E194K, G196E, T200A, E204T, Q207D, V245M, K277R, I293V, E297K, Q334L, Y354H, V365I, T377P, V381I, K390R, E399D, A400M, V435L, E449D, L452I, K527N  
ES_X2524-2 ES_X2524-2 None None   V35I, T69S, I135T, T139I, E169K, R172K, E194K, F214L, V245K, K277R, T286A, I293V, E297R, V317A, A376T, K390R, Q394L, E399D, A400T, K431T, V435A, G436D, A446S, L452Q, R461K, V466A, D471E, T477A, Q480H, H483Q, L491S, A502V, Q509L, S519N, A534S, V559I  
ES_X2556-3 ES_X2556-3 None None   V8I, R83K, D123N, K166R, E169K, P176S, E194D, G196E, T200A, E204K, R211A, K277R, R284RK, T286A, P294T, E297K, E300K, I329L, W337R, R356K, T369V, A376S, K385R, K390R, E404D, V435I, D460N, L469I, L491S, L517I, K530R, V559I  
P2149-3 P2149-3 None None   V60I, S68G, D121N, K122E, D123N, E169K, R172K, D177E, I178L, E194K, I195L, I293V, E297A, M357I, A376S, K390R, A400T, T403M, E404D, N418S, A446S, E449D, H483N, I506L, E516K, K527N, K530R, A554N, K558R  
X1999-5 X1999-5 None None   V35T, E40D, K49R, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291ED, V292VI, I293V, E297A, I309V, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, T377M, Q394R, A400V, E413D, Q428R, K431T, V435A, A437T, F440Y, L452I, R461K, R463K, V466I, V467I, S468T, D471E, T477A, H483Q, L491S, K512R, S519N, A534S, A554S, V559I  
X2555-2 X2555-2 None None   K49R, V60I, V90I, D123E, I135T, I142V, S163A, K166T, F171Y, I178M, E194K, T200A, K201R, I202V, R211K, A272P, K277R, T286A, P294T, K311R, D324E, Q334E, A376S, K390R, A400S, E449D, T450S, E516K  
X2574-2 X2574-2 None None   V60I, K104R, D121Y, K122E, I135T, I142V, S162A, E169K, R172K, V179I, E194K, T200N, R211K, V245K, L283I, R284K, T286V, A288S, I293V, E297D, E300A, I329L, Q334N, T338S, M357T, R358K, G359S, K390R, Q394S, K431T, A446S, V467I, S468T, T470A, Q509K, K530R, I556V  
X2634-2 X2634-2 None None  V179E V35T, V60I, K122E, D123S, E138A, S162C, E169K, K173I, Q174K, E194K, T200A, Q207K, R211S, V245Q, E248D, A272P, K281R, T286A, E291D, V292I, I293V, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, I375V, A376S, V381I, K390R, Q394R, K395R, A400T, E413D, Q428R, K431T, V435A, Y441F, N447S, R463K, V467I, S468T, T470S, D471E, T477A, H483Q, L484I, L491S, K512R, S519N, A534S, A554S  
X2689-2 X2689-2 None None  V108I, F227L V35I, V118I, K122E, I135T, T200E, E203K, L210M, F214L, K223T, A272P, K277R, K311R, I329L, T338S, R356K, M357T, A360T, A400T, E404D, R463K, E516K, L533M, I556V