<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Charpentier (2011)
Title Hot spots of integrase genotypic changes leading to HIV-2 resistance to raltegravir.
Citation AAC
SelectedGene IN
SelectedSpecies HIV2
SelectedType Clinical
NumIsolates 11
NumPts 6
Host Human

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
12034GADC 012034GADC RAL  Y143C T97A, S138T N30Q, S39T, A41S, A56S, I72V, I84V, Q137H, S163D, I172M, I180A, A215S, L220F S23Q, R34K, Q42L, L58V, Q91R, S93T, S106G, S197A, L200I, T205A, D222N, F227Y 
   RAL  Y143C T97A, S138T N30Q, S39T, A41S, A56S, I72V, I84V, A119AT, Q137H, S163D, I172M, I180A, A215S, L220F S23Q, R34K, Q42L, L58V, Q91R, S93T, S106G, S197A, L200I, T205A, D222N, F227Y 
13001UZQJ 013001UZQJ RAL  Y143YH S138T S17G, S23V, N30Q, I84V, S163D, I175V, L213F, S218L, L220F, L250I, D256E, D270H, S277C, G278S, S279A, G283D, D286A R34K, A41D, Q42K, S93T, E125D, I133V, E167D, N170V, T171S, I180V, S197A, I201V, K221Q, D222N, R224Q, F227Y, V251I, I259V, Q273K, M275L, H280D, L281V, E285Q, G287R 
   RAL  N155H S138T S17G, S23V, N30Q, I84V, E92X, S163D, I175V, L213F, S218L, L220F, L250I, D256E, D270H, S277R, G278S, S279A, G283D, D286A K14KN, R34K, A41D, Q42KR, S93T, E125D, I133V, A153G, E167D, N170V, T171S, I180V, S197A, I201V, K221Q, D222N, R224Q, F227Y, V251I, I259V, Q273K, M275L, H280D, L281V, E285Q, G287R 
13015FTOP 013015FTOP RAL  N155H T97A, S138T Y15F, S17G, S23V, N30Q, I50V, H51Q, I72V, I84IV, L99LH, Q124QR, S163D, I175V R34K, A41D, Q42K, S93T, E125D, I133V, E167D, N170V, T171S, I180V 
44001ERNC 044001ERNC RAL  G140S, Q148R  N30Q, S39T, T60V S23I, L58I, I133V, V141I, I180V 
   RAL  G140S, Q148R  N30Q, S39T, T60V S23I, L58I, M63MT, S106SN, I133V, V141I, I180V 
51010NKEE 051010NKEE RAL  Q148K  S23V, N30Q, S39T, T60V, A119P, S163N, A215R, K219N, L220F, L250I, G278S V19I, R34K, A41T, L58V, I133V, I180V, S197A, E207D, D222N, R224Q, F227Y, I259V, M275L, S279P, G283S 
   RAL  G140S, Q148R  S23V, N30Q, S39T, Q44QH, T60V, S163N, A215R, S218SL, K219N, L220LF, D222X, L250I, G278S V19I, R34K, A41T, L58V, A119S, I133V, V141VI, I180V, S197A, E207D, R224RQ, F227Y, G237GR, I259V, M275L, S279P, G283S 
GBO GBO RAL  Y143C T97A S39T, H156R, I172M, E198G, E246D, L250I K20Q, I28L, N30K, I133V, A153S, I180V, D222N, I259V, E274G, H280N 
   RAL   T97A, Y143G S39T, A119T, H156R, I172M, E246D, L250I K4R, K20Q, I28L, N30K, Q91R, S93T, I133V, A153S, H157Y, I180V, S197A, I201IV, D222N, I259V, E274G, H280N