<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Charpentier (2011)
Title Hot spots of integrase genotypic changes leading to HIV-2 resistance to raltegravir.
Citation AAC
SelectedGene IN
SelectedSpecies HIV2
SelectedType Clinical
NumIsolates 11
NumPts 6
Host Human

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
12034GADC 012034GADC RAL  Y143C T97A, S138T L30Q, S39T, A41S, A56S, V60T, I72V, I84V, P119A, Q137H, S163D, I172M, V180A, R215S, I250L, V259I, V260I I18N, I19V, T23Q, R34K, Q42L, I58V, Y65C, Q91R, S93T, S106G, V133I, L200I, T205A, N219K, Q224R, L277M, S280G, P281S 
   RAL  Y143C T97A, S138T L30Q, S39T, A41S, A56S, V60T, I72V, I84V, P119AT, Q137H, S163D, I172M, V180A, R215S, I250L, V259I, V260I I18N, I19V, T23Q, R34K, Q42L, I58V, Y65C, Q91R, S93T, S106G, V133I, L200I, T205A, N219K, Q224R, L277M, S280G, P281S 
13001UZQJ 013001UZQJ RAL  Y143YH S138T S17G, T23V, L30Q, V60T, I84V, P119A, S163D, I175V, L213F, S218L, D256E, V260I, D270H I18N, I19V, R34K, A41D, Q42K, I58L, Y65C, S93T, E125D, E167D, N170V, T171S, I201V, R215A, N219K, K221Q, V251I, R274G, Q275K, S279C, P281A, H282D, L283V, G285D, A286T, E288Q 
   RAL  E92EAPQ, N155H S138T S17G, T23V, L30Q, V60T, I84V, P119A, S163D, I175V, L213F, S218L, D256E, V260I, D270H K14KN, I18N, I19V, R34K, A41D, Q42KR, I58L, Y65C, S93T, E125D, A153G, E167D, N170V, T171S, I201V, R215A, N219K, K221Q, V251I, R274G, Q275K, S279R, P281A, H282D, L283V, G285D, A286T, E288Q 
13015FTOP 013015FTOP RAL  N155H T97A, S138T Y15F, S17G, T23V, L30Q, I50V, H51Q, V60T, I72V, I84IV, L99LH, P119A, Q124QR, S163D, I175V I18N, I19V, R34K, A41D, Q42K, I58L, Y65C, S93T, E125D, E167D, N170V, T171S 
44001ERNC 044001ERNC RAL  G140S, Q148R  L30Q, S39T, P119A, F220L, Y227F, I250L, V259I, V260I I18N, I19V, T23I, Y65C, V141I, A197S, R215A, N219K, N222D, Q224R, L277M, S280G, P281S 
   RAL  G140S, Q148R  L30Q, S39T, P119A, F220L, Y227F, I250L, V259I, V260I I18N, I19V, T23I, M63MT, Y65C, S106SN, V141I, A197S, R215A, N219K, N222D, Q224R, L277M, S280G, P281S 
51010NKEE 051010NKEE RAL  Q148K  T23V, L30Q, S39T, S163N, V260I I18N, R34K, A41T, I58V, Y65C, E207D, G285S 
   RAL  G140S, Q148R  T23V, L30Q, S39T, Q44QH, S163N, S218SL, F220FL, N222NK, V260I I18N, R34K, A41T, I58V, Y65C, P119S, V141VI, E207D, Q224QR, G237GR, G285S 
GBO GBO RAL  Y143C T97A T23S, S39T, V60T, P119A, H156R, I172M, E198G, F220L, Y227F, E246D, V260I I18N, I19V, K20Q, I28L, L30K, I58L, Y65C, A153S, A197S, R215A, N219K, Q224R, E276G, L277M, S280G, P281S, H282N 
   RAL   T97A, Y143G T23S, S39T, V60T, P119T, H156R, I172M, F220L, Y227F, E246D, V260I K4R, I18N, I19V, K20Q, I28L, L30K, I58L, Y65C, Q91R, S93T, A153S, H157Y, I201IV, R215A, N219K, Q224R, E276G, L277M, S280G, P281S, H282N