<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Jallow (2006)
Title Virological and immunological response to Combivir and emergence of drug resistance mutations in a cohort of HIV-2 patients in The Gambia.
Citation AIDS
SelectedGene RT
SelectedSpecies HIV2
SelectedType Clinical
NumIsolates 28
NumPts 8
Host Human

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
DTS_1 DTS_1-3 AZT, 3TC None  I181V M11S, K20R, K43R, D123N, P126Q, H162Y, I180L, R200K, H228R, I244L, R307K, E334S, V357I, N359H, K388KR V5I, I8M, I10V, R22K, R104K, A138I, V167I, K176P, D195G, Y227F, L270I, H317N, V329I, Q333L, H342HL, E345D, I397T, A426T 
  DTS_1-5 AZT, 3TC None  I181V M11S, K20R, K35R, K43R, K66R, P126Q, H162Y, F171L, I180L, R200K, H228K, I244L, R307K, E334S, V357I V5I, I8M, I10V, R22K, R104K, A138I, V167I, K176P, D195G, V201A, Y227F, L270I, H317N, V329I, Q333L, E345D, V351G, N359Y, T360A, I365V, I397T, A426T 
  DTS_1-6 AZT, 3TC None  I181V M11S, K20R, K43R, P126Q, H162Y, I180L, R200K, H228K, I244L, R307K, E334S, V357I V5I, I8M, I10V, R22K, R104K, A138I, V167I, K176P, D195G, V201A, Y227F, L270I, H317N, V329I, Q333L, E345D, N359Y, T360A, I365V, I397T, A426T 
DTS_2 DTS_2-8 AZT, 3TC None   M11T, K28R, I31V, P126Q, H162Y, I180L, H228Q, I251V, R307K, E334D, E344G, E396D V5I, V135I, V167I, K176P, Y227F, L270I, H317C, I365V, R385K, I397T, G431K 
  DTS_2-9 AZT, 3TC None M184V  M11T, K28R, I31V, P126Q, H162Y, L168X, I180L, H228Q, I251V, R307K, E334D, E344G, E396D V5I, E122K, V135I, V167I, K176P, N210NH, Y227F, L270I, Y271YS, R281RW, H317C, I365V, I397T, G431K 
  DTS_2-10 AZT, 3TC None M184I  M11T, K28R, I31V, P126Q, H162Y, Q166R, I180L, H228Q, I251V, R307K, E334D, E344G, E396D V5I, V167I, K176P, Y227F, L270I, H317C, I365V, I397T, G431K 
  DTS_2-11 AZT, 3TC None M184V  M11T, K28R, I31V, P126Q, H162Y, I180L, H228Q, I251V, R307K, E334D, E344G, E396D V5I, V135I, V167I, K176P, L270I, H317C, I365V, I397T, G431K 
DTS_3 DTS_3-12 AZT, 3TC None   M11T, T58S, D86E, D123G, P126Q, H162Y, K176S, R200K, H228Q, P247PL, I251V, K277R, E334H, E344A, K358E, N404D, G431Q V5I, I10V, I90V, H121W, S134A, A138I, L270I, N306S, T360A, I365V, I397T 
  DTS_3-16 AZT, 3TC None Q151M, M184V  M11T, T58S, D86E, A98X, D123G, H162Y, R200K, H228Q, I251V, K277R, E334H, I341V, E344A, N404D, G431Q I8V, I10V, I90V, H121W, S134A, A138V, M164V, K176P, L270I, H317HQ, T360A, I365V, Q370QH, I397T 
  DTS_3-17 AZT, 3TC None Q151M, M184V  M11T, T58S, D86E, D123DG, H162Y, R200K, H228Q, I251V, K277R, E334H, I341V, E344A, V357VI, N404D, Y405YH I8V, I10V, I90V, H121W, S134A, A138V, M164V, K176P, G262GD, L270I, E345EG, T360A, I365V, I397T 
  DTS_3-18 AZT, 3TC None Q151M, M184V  P7S, M11T, T58S, V111I, D123G, V135A, H162Y, R200K, V201M, F214L, K223R, H228Q, I251V, K277R, E334H, I341V, E344A, N404D, G431Q I8V, I10V, T53S, I90V, H121W, S134A, A138V, K176P, L270I, S311G, T360A, I365V, I397T 
  DTS_3-18B AZT, 3TC None Q151M, M184V L188V M11T, K35R, T58S, V111I, D123G, H162Y, R200K, F214L, K223R, I251V, K277R, E334H, I341V, E344A, N404D I8V, I10V, T53S, I90V, V108VG, H121W, S134A, A138V, K176P, L270I, T360A, I365V, I397T 
DTS_4 DTS_4-19 AZT, 3TC None   M11T, K28R, I31V, K64R, K66R, P126Q, H162Y, I180L, H228Q, I251V, Q294L, R307K, K323E, E334D, E344G, E396D R104K, V135I, V167I, K176P, D195N, Y227F, L270I, M287K, E304A, H317Y, I365V, I397T, A426V, G431K 
  DTS_4-20 AZT, 3TC None M184V  M11T, K28R, I31V, K64R, K66R, P126Q, H162Y, I180L, H228Q, I251V, Q294L, R307K, K323E, E334D, E344G, V372I, E396D, D415DG R104K, V135I, V167I, K176P, D195N, Y227F, L270I, M287K, E304A, H317C, I365V, I397T, A426V, G431K 
DTS_5 DTS_5-21 AZT, 3TC None   K43KR, K64R, D86E, H162HY, K173E, K323E, E334D, E344G, K347KR V5I, I10V, P51S, I251S, I348V, I365V, I397T 
  DTS_5-22A AZT, 3TC None   M11MT, K35KR, K64R, D86E, H162Y, K173KE, A174AT, K176KQ, M184X, K323E, E334D, E344G K4R, V5I, I10V, P51S, I75V, I251S, I348V, I365V, I397T 
  DTS_5-23 AZT, 3TC None M184V  K64R, K82R, D86E, H162Y, K176Q, K323E, E334D, E344G V5I, I10V, P51S, I251S, I348V, I365V 
  DTS_5-24 AZT, 3TC None M184V  M11T, K35KR, K43KR, K64R, D86E, H162Y, K176Q, R307RK, K323E, E334D, E344G, K347R, V357X V5VI, I10V, P51S, I251S, V263VI, I348V, I365V, I397T 
DTS_6 DTS_6-26 AZT, 3TC None   M11T, K43R, K64R, N69S, D86E, V111I, H121C, H162Y, K176Q, I179T, G211N, H228Q, I244L, I251V, K277R, R284RK, R307K, H317X, K331R, E334D, E344EG, E345X, T362X, E396D, V417T V2I, I8V, I10V, A101V, R104K, P126K, L132I, Q166H, V167I, Y227F, L270I, D332N, H342HP, I365V, E378ED, I397T, N404S, D413E 
  DTS_6-28 AZT, 3TC None M184V  M11T, K64R, K82KR, D86E, V111I, H121C, H162Y, K176Q, I179T, H228Q, I244L, I251V, K277R, R307K, K331R, E334D, E396D, V417T V2I, I8V, I10V, P126K, L132I, Q166H, V167I, Y227F, L270I, H317Y, D332N, E345N, K358R, I365V, I397T, N404S, D413E 
  DTS_6-29 AZT, 3TC None A62V, K65R, M184V  M11T, K64R, N69S, D86E, V111I, H121C, H162Y, Q166N, K176Q, I179T, H228Q, I244L, I251V, K277R, R307K, E334D, E344G, E396D, V417T V2I, I8V, I10V, P126K, L132I, K147KN, V167I, Y227F, L270I, H317Y, D332N, I365V, I397T, N404S, D413E 
  DTS_6-29A AZT, 3TC None A62AV, K65KR, M184V  M11T, K43R, K64R, N69NS, D86E, V111I, H121C, H162Y, Q166X, K176Q, I179T, H228Q, I244L, I251V, K277R, R307K, K331R, E334D, E344EG, E345X, L380LV, E396D, W414WR, V417T V2I, I8V, I10V, P59PL, P126K, L132I, V167I, Y227F, L270I, H317Y, D332N, I365V, I397T, N404S, D413E 
DTS_7 DTS_7-30 AZT, 3TC None   K9X, M11T, I31L, K43R, P126Q, H162Y, K173R, I180L, H228Q, I251V, R307K, E334D, E396D V5I, I10V, A101V, V135I, V167I, K176P, D224H, L270I, H317C, I341M, I365V, A426V, G431K 
  DTS_7-34A AZT, 3TC None M184V, I348IM  M11T, K28KR, K64R, P126Q, H162Y, I180L, K223E, H228Q, K249KN, I251V, K277X, M287X, R307K, L325X, E334D, E344X, L368X, E396D V5I, I10V, I63L, P150Q, V167I, K176P, D224H, L270I, I309IM, H317C, K323KN, N363NK, I365V 
DTS_8 DTS_8-35 AZT, 3TC None   M11A, K28R, K64R, V111I, L132V, A138T, A158T, H162Y, I179T, H228Q, I244L, K277R, R284K, R307K, E334H, E344G, E396D, V417I V2I, R104K, P126K, Q166H, V167I, K176P, D195N, L270I, H317C, V329I, D332N, E345D, K347N, I365V, I397T, N404S, D413E, R424RG, A426I, G431K 
  DTS_8-39 AZT, 3TC None M184V, S215Y L100I M11T, K20KR, K28R, K40R, K64KR, V111I, A138T, A158AT, H162Y, I179T, K223R, H228Q, I244L, I251IT, K277R, R284K, R307K, E334H, E344G, E396D, V417I V2VI, K4R, I10V, R22RK, R104K, I118V, P126K, L132I, Q166H, V167I, K176P, D195N, L270I, R281RK, M287L, H317C, V329VI, D332N, E345D, K347N, I365V, I397T, N404S, D413DE, A426V, G431K 
  DTS_8-39A AZT, 3TC None M184V, S215Y L100I M11T, K28R, K40R, K64KR, V111I, A138T, H162Y, I179T, K223R, H228Q, I244L, I251IT, K277R, R284K, R307K, E334H, E344G, E396D, V417I V2VI, K4KR, I10V, R22RK, R104K, I118V, P126K, L132I, Q166H, V167I, K176P, D195N, L270I, M287L, H317C, D332N, E345D, K347N, I365V, I397T, N404S, Q407QR, D413E, A426V 
  DTS_8-39B AZT, 3TC None M184V, S215Y L100I M11T, K28R, K40R, K64R, V111I, A138T, H162Y, I179T, K223R, H228Q, I244L, I251IT, K277R, R284K, R307K, E334H, E344G, V357VI, E396D, V417I K4KR, I10V, R22K, R104K, I118V, P126K, L132I, Q166H, V167I, K176P, D195N, L270I, R281RK, M287L, H317C, V329VI, D332N, E345D, K347N, I365V, I397T, N404S, D413E, A426V, G431K