<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Jallow (2006)
Title Virological and immunological response to Combivir and emergence of drug resistance mutations in a cohort of HIV-2 patients in The Gambia.
Citation AIDS
SelectedGene RT
SelectedSpecies HIV2
SelectedType Clinical
NumIsolates 28
NumPts 8
Host Human

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
DTS_1 DTS_1-3 AZT, 3TC None  I181V T11S, K43R, D123N, Q228R, D250E, S272P, G334S, H335N, N359H, V365I, K388KR, E413D I8M, S107T, I108V, A134S, M138I, V167I, C232Y, Y317N, S332D, Q333L, H342HL, E345D 
  DTS_1-5 AZT, 3TC None  I181V T11S, K35R, K43R, K66R, F171L, Q228K, D250E, S272P, G334S, H335N, E413D I8M, S107T, I108V, A134S, M138I, V167I, V201A, C232Y, Y317N, S332D, Q333L, E345D, V351G, N359Y, T360A 
  DTS_1-6 AZT, 3TC None  I181V T11S, K43R, Q228K, D250E, S272P, G334S, H335N, E413D I8M, S107T, I108V, A134S, M138I, V167I, V201A, C232Y, Y317N, S332D, Q333L, E345D, N359Y, T360A 
DTS_2 DTS_2-8 AZT, 3TC None   V10I, K22R, K28R, I31V, K104R, M138A, K200R, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, E396D, E413D R20K, S107T, I108V, A134S, V135I, V167I, G195D, C232Y, L244I, Y317C, S332D, R385K, T426A, G431K 
  DTS_2-9 AZT, 3TC None M184V  V10I, K22R, K28R, I31V, K104R, M138A, K200R, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, E396D, E413D R20K, S107T, I108V, E122K, A134S, V135I, V167I, L168L*IK, G195D, N210NH, C232Y, L244I, Y271YS, R281RW, Y317C, S332D, T426A, G431K 
  DTS_2-10 AZT, 3TC None M184I  V10I, K22R, K28R, I31V, K104R, M138A, Q166R, K200R, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, E396D, E413D R20K, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, Y317C, S332D, T426A, G431K 
  DTS_2-11 AZT, 3TC None M184V  V10I, K22R, K28R, I31V, K104R, M138A, K200R, F227Y, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, E396D, E413D R20K, S107T, I108V, A134S, V135I, V167I, G195D, C232Y, L244I, Y317C, S332D, T426A, G431K 
DTS_3 DTS_3-12 AZT, 3TC None   K22R, T58S, D86E, K104R, D123G, P176S, F227Y, P247PL, D250E, I251V, S272P, K277R, I329V, G334H, H335N, E344A, I357V, K358E, N404D, E413D, G431Q R20K, I90V, S107T, I108V, H121W, M138I, L180I, G195D, C232Y, L244I, N306S, K307R, Y317H, S332D, T360A, T426A 
  DTS_3-16 AZT, 3TC None Q151M, M184V A98AEGV I5V, K22R, T58S, D86E, K104R, D123G, F227Y, D250E, I251V, S272P, K277R, I329V, G334H, H335N, I341V, E344A, I357V, N404D, E413D, G431Q I8V, R20K, I90V, S107T, I108V, H121W, Q126P, M138V, M164V, L180I, G195D, C232Y, L244I, K307R, Y317HQ, S332D, T360A, Q370QH, T426A 
  DTS_3-17 AZT, 3TC None Q151M, M184V  I5V, K22R, T58S, D86E, K104R, D123DG, F227Y, D250E, I251V, S272P, K277R, I329V, G334H, H335N, I341V, E344A, I357IV, N404D, Y405YH, E413D I8V, R20K, I90V, S107T, I108V, H121W, Q126P, M138V, M164V, L180I, G195D, C232Y, L244I, G262GD, K307R, Y317H, S332D, E345EG, T360A 
  DTS_3-18 AZT, 3TC None Q151M, M184V  I5V, P7S, K22R, T58S, K104R, V111I, D123G, V135A, V201M, F214L, K223R, F227Y, D250E, I251V, S272P, K277R, I329V, G334H, H335N, I341V, E344A, I357V, N404D, E413D, G431Q I8V, R20K, T53S, I90V, S107T, I108V, H121W, Q126P, M138V, L180I, G195D, C232Y, L244I, K307R, S311G, Y317H, S332D, T360A, T426A 
  DTS_3-18B AZT, 3TC None Q151M, M184V L188V I5V, K22R, K35R, T58S, K104R, V111I, D123G, F214L, K223R, F227Y, Q228H, D250E, I251V, S272P, K277R, I329V, G334H, H335N, I341V, E344A, I357V, N404D, E413D I8V, R20K, T53S, I90V, S107T, I108GV, H121W, Q126P, M138V, L180I, G195D, C232Y, L244I, K307R, Y317H, S332D, T360A, T426A 
DTS_4 DTS_4-19 AZT, 3TC None   I5V, V10I, K22R, K28R, I31V, K64R, K66R, M138A, K200R, D250E, I251V, S272P, Q294L, K323E, I329V, G334D, H335N, E344G, I357V, E396D, E413D R20K, S107T, I108V, A134S, V135I, V167I, G195N, C232Y, L244I, M287K, E304A, S332D, T426V, G431K 
  DTS_4-20 AZT, 3TC None M184V  I5V, V10I, K22R, K28R, I31V, K64R, K66R, M138A, K200R, D250E, I251V, S272P, Q294L, K323E, I329V, G334D, H335N, E344G, I357V, V372I, E396D, E413D, D415DG R20K, S107T, I108V, A134S, V135I, V167I, G195N, C232Y, L244I, M287K, E304A, Y317C, S332D, T426V, G431K 
DTS_5 DTS_5-21 AZT, 3TC None   T11M, K22R, K43KR, K64R, D86E, K104R, M138A, Y162YH, K173E, P176K, K200R, F227Y, Q228H, D250E, S272P, K323E, I329V, G334D, H335N, E344G, K347KR, I357V R20K, P51S, S107T, I108V, Q126P, A134S, L180I, G195D, C232Y, L244I, I251S, I270L, K307R, Y317H, S332D, I348V 
  DTS_5-22A AZT, 3TC None M184MIV  T11TM, K22R, K35KR, K64R, D86E, K104R, M138A, K173KE, A174AT, P176KQ, K200R, F227Y, Q228H, D250E, S272P, K323E, I329V, G334D, H335N, E344G, I357V K4R, R20K, P51S, I75V, S107T, I108V, Q126P, A134S, L180I, G195D, C232Y, L244I, I251S, I270L, K307R, Y317H, S332D, I348V 
  DTS_5-23 AZT, 3TC None M184V  T11M, K22R, K64R, K82R, D86E, K104R, M138A, P176Q, K200R, F227Y, Q228H, D250E, S272P, K323E, I329V, G334D, H335N, E344G, I357V R20K, P51S, S107T, I108V, Q126P, A134S, L180I, G195D, C232Y, L244I, I251S, I270L, K307R, Y317H, S332D, I348V 
  DTS_5-24 AZT, 3TC None M184V  I5IV, K22R, K35KR, K43KR, K64R, D86E, K104R, M138A, P176Q, K200R, F227Y, Q228H, D250E, S272P, K323E, I329V, G334D, H335N, E344G, K347R, E413D R20K, P51S, S107T, I108V, Q126P, A134S, L180I, G195D, C232Y, L244I, I251S, V263VI, I270L, K307KR, Y317H, S332D, I348V, I357IMV 
DTS_6 DTS_6-26 AZT, 3TC None   I5V, K22R, K43R, K64R, N69S, D86E, V111I, H121C, M138A, P176Q, I179T, K200R, G211N, D250E, I251V, S272P, K277R, R284RK, I329V, K331R, G334D, H335N, E344EG, I357V, E396D, V417T V2I, I8V, R20K, A101V, S107T, I108V, Q126K, L132I, A134S, Q166H, V167I, L180I, G195D, C232Y, Y317YF, S332N, H342HP, E345KN, T362THNP, E378ED, N404S 
  DTS_6-28 AZT, 3TC None M184V  I5V, K22R, K64R, K82KR, D86E, K104R, V111I, H121C, M138A, P176Q, I179T, K200R, D250E, I251V, S272P, K277R, I329V, K331R, G334D, H335N, I357V, E396D, V417T V2I, I8V, R20K, S107T, I108V, Q126K, L132I, A134S, Q166H, V167I, L180I, G195D, C232Y, S332N, E345N, K358R, N404S, T426A 
  DTS_6-29 AZT, 3TC None A62V, K65R, M184V  I5V, K22R, K64R, N69S, D86E, K104R, V111I, H121C, M138A, Q166N, P176Q, I179T, K200R, D250E, I251V, S272P, K277R, I329V, G334D, H335N, E344G, I357V, E396D, V417T V2I, I8V, R20K, S107T, I108V, Q126K, L132I, A134S, K147KN, V167I, L180I, G195D, C232Y, S332N, N404S, T426A 
  DTS_6-29A AZT, 3TC None A62AV, K65KR, M184V  I5V, K22R, K43R, K64R, N69NS, D86E, K104R, V111I, H121C, M138A, P176Q, I179T, K200R, D250E, I251V, S272P, K277R, I329V, K331R, G334D, H335N, E344EG, I357V, L380LV, E396D, W414WR, V417T V2I, I8V, R20K, P59PL, S107T, I108V, Q126K, L132I, A134S, Q166HN, V167I, L180I, G195D, C232Y, S332N, E345EDKN, N404S 
DTS_7 DTS_7-30 AZT, 3TC None   K22R, I31L, K43R, K104R, M138A, K173R, K200R, F227Y, D250E, I251V, S272P, I329V, G334D, H335N, I357V, E396D, T397I, E413D K9K*EQ, R20K, A101V, S107T, I108V, A134S, V135I, V167I, G195D, D224H, C232Y, L244I, Y317C, S332D, I341M, T426V, G431K 
  DTS_7-34A AZT, 3TC None M184V, I348IM  K22R, K28KR, K64R, K104R, M138A, K200R, K223E, F227Y, K249KN, D250E, I251V, S272P, L325LIV, I329V, G334D, H335N, E344EAGV, I357V, L368X, E396D, T397I, E413D R20K, I63L, S107T, I108V, A134S, P150Q, V167I, G195D, D224H, C232Y, L244I, K277KIRT, M287MKRT, I309IM, Y317C, K323KN, S332D, N363NK 
DTS_8 DTS_8-35 AZT, 3TC None   I5V, V10I, T11A, K22R, K28R, K64R, V111I, L132V, M138T, A158T, I179T, K200R, F227Y, D250E, S272P, K277R, R284K, G334H, H335N, E344G, I357V, E396D, V417I V2I, R20K, S107T, I108V, Q126K, A134S, Q166H, V167I, L180I, G195N, C232Y, Y317C, S332N, E345D, K347N, N404S, R424RG, T426I, G431K 
  DTS_8-39 AZT, 3TC None M184V, S215Y L100I I5V, K22KR, K28R, K40R, K64KR, V111I, M138T, A158AT, I179T, K200R, K223R, F227Y, D250E, I251IT, S272P, K277R, R284K, I329IV, G334H, H335N, E344G, I357V, E396D, E413ED, V417I V2VI, K4R, R20RK, S107T, I108V, I118V, Q126K, L132I, A134S, Q166H, V167I, L180I, G195N, C232Y, R281RK, M287L, Y317C, S332N, E345D, K347N, N404S, T426V, G431K 
  DTS_8-39A AZT, 3TC None M184V, S215Y L100I I5V, K22KR, K28R, K40R, K64KR, V111I, M138T, I179T, K200R, K223R, F227Y, D250E, I251IT, S272P, K277R, R284K, I329V, G334H, H335N, E344G, I357V, E396D, V417I V2VI, K4KR, R20K, S107T, I108V, I118V, Q126K, L132I, A134S, Q166H, V167I, L180I, G195N, C232Y, M287L, Y317C, S332N, E345D, K347N, N404S, Q407QR, T426V 
  DTS_8-39B AZT, 3TC None M184V, S215Y L100I I5V, K28R, K40R, K64R, V111I, M138T, I179T, K200R, K223R, F227Y, D250E, I251IT, S272P, K277R, R284K, I329IV, G334H, H335N, E344G, I357IV, E396D, V417I K4KR, R20K, S107T, I108V, I118V, Q126K, L132I, A134S, Q166H, V167I, L180I, G195N, C232Y, R281RK, M287L, Y317C, S332N, E345D, K347N, N404S, T426V, G431K