Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Salgado (2009)
Title Mutation N155H in HIV-2 integrase confers high phenotypic resistance to raltegravir and impairs replication capacity.
Citation J Clin Virol
SelectedGene IN
SelectedSpecies HIV2
SelectedType Clinical
NumIsolates 5
NumPts 1
Host Human

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
SP-2p2 SP-2p2-175 None    S17T, N30Q, S39T, I72V, R164K, Q214H, A215T, S218L, L250I, G278GS V19I, I28L, A41P, L58V, S93T, I133V, I180V, S197A, I210T, D222N, I259V, I260V, M275L 
  SP-2p2-183 RAL 44   S17T, N30Q, S39T, I72V, R164K, Q214H, A215T, S218L, L250I, G278GS V19I, I28L, A41P, L58V, S93T, I133V, I180V, S197A, I210T, D222N, I259V, I260V, M275L 
  SP-2p2-185 RAL 54 N155H  S17T, N30Q, S39T, I84V, R164K, Q214H, A215T, S218L, L250I V19I, I28L, A41P, L58V, S93T, I133V, A153G, N160K, I180V, S197A, I210T, D222N, I259V, I260V, M275L 
  SP-2p2-189 RAL 72 N155H  S17T, N30Q, S39T, I72IV, I84V, R164K, Q214H, A215T, S218L, L250I, G278S V19I, I28L, A41P, L58V, S93T, I133V, Q148Q*, A153G, N160K, S163SG, I180V, S197A, I210T, D222N, I259V, I260V, M275L 
  SP-2p2-192 RAL 83 N155H  E13D, S17T, I28X, N30Q, S39T, H51HR, I84V, R164K, Q214H, A215T, S218L, L250I, G278S Y15C, V19I, E21K, G27GV, A33AG, A41P, L58V, S93T, I133V, A153G, N160K, S163SG, I180V, S197A, I210T, D222N, I259V, I260V, M275L