<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Bercoff (2010)
Title Polymorphisms of HIV-2 integrase and selection of resistance to raltegravir.
Citation Retrovirology
SelectedGene RT
SelectedSpecies HIV2
NumIsolates 47
NumPts 47
Host Human


Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
19970068 97068 None None   K22R, K43R, K82R, K104R, M138AS, Y162H, K200R, F227Y, D250E, I251V, S272P, E297D, I329V, G334D, H335N, E344G, I357V R20K, S107T, I108V, Q126P, A134S, I145IT, V167I, G195D, C232Y, L244I, Y317H, S332D, G384GE 
19980385 98385 None None N69G, E219D  T11Q, K22R, E36K, K43R, K64R, K82R, D86E, K104R, H121Y, D123E, M138A, Y162H, K173R, N175H, K200R, K249KR, D250E, I251V, S272P, E297D, I329V, G334D, H335N, E344G R20K, E29EK, S107T, I108V, A134S, G195D, V201A, C232Y, E233K, L244I, L298I, S332D, I357M, K358R, G384E 
19990547 96288 None None   I5V, K22R, T58S, K64R, D86E, K103R, K104R, Y162H, K200R, F227Y R20K, S107T, I108V, H121D, M138I, V167I, G195D, C232Y 
20010473 2001473 None None I75M  I5V, V10I, T11M, K22R, K64R, K82R, K104R, M138A, K200R, F227Y, K249KR, D250E, S272P, G334D, H335N, I341IV, E344G, I357V I8IM, K9N, R20K, E42V, T60V, S107T, I108V, E122K, Q126P, L132I, A134S, I145T, L180I, I189V, G195D, L212I, S215T, C232Y, L244I, I251IMV, V293I, Y317H, S332D 
20010866 2001866 None None   T11E, K22R, K104KR, D123K, M138A, K200R, F227Y, Q228H, D250E, I251V, Y271H, S272P, K277R, I329V, G334D, H335N, I341IV, E344G, I357V R20K, S107T, I108V, A134S, P176PLMT, L180I, G195D, C232Y, L244I, I270L, R281RK, K307R, Y317H, S332N 
20040941 2004941 None None   T11E, K22R, K104R, D123N, M138A, K200R, F227Y, Q228R, D250E, I251V, Y271H, S272P, K277R, I329V, G334D, H335N, E344G, I357V R20K, S107T, I108V, A134S, P176M, L180I, G195D, V201A, C232Y, L244I, I270L, R281RK, K307R, Y317H, S332N 
20050011 2003026 None None   V10I, T11M, K22R, K104R, M138A, F227Y, Q228H, D250E, S272P, K277R, I329V, G334D, H335N, I341V, E344G, K347R, I357V R20K, S107T, I108V, A134S, P176M, L180I, G195D, C232Y, L244I, I270L, K307R, Y317H, S332D 
20050388 20050388 None None   E6Q, T11M, K22R, K43R, K64R, K66R, D86E, K104R, D123E, M138A, F227Y, Q228K, S272P, K277R, I329V, G334D, H335N, E344G, I357V, N359H, V365I R20K, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, K286R, M287K, N306D, S332D 
20050508 20050508 None None   V10I, T11M, K22R, K28R, K43R, K64R, K104R, V111I, M138A, A174T, P176S, F227Y, Q228R, D250E, I251V, S272P, K277R, I329V, G334D, H335N, I341V, E344G, I357V R20K, I63V, S107T, I108V, L180I, G195D, C232Y, L244I, Y317H, S332D 
20050775 20050775 None None  I181V K22R, K28KR, K104R, V111VI, H121Y, D123G, M138A, I145V, K200R, F227Y, T237A, D250E, I251V, S272P, K277R, I329V, G334D, H335N, E344G I8IV, R20K, P51S, I63V, T88K, S107T, I108V, Q126P, A134S, V167I, G195D, C232Y, L244I, Y317C, S332D 
20070313 20070313 None None  A101P I5V, K22R, K104R, H121C, M138A, Y162W, K200R, F227Y, T237N, I251V, S272P, K277R, E322G, I329V, Q330L, G334D, H335N I8V, R20K, P51S, S107T, I108V, A134S, V167I, G195D, C232Y, L244I, K286KR, Y317H, S332D 
20080321 20080321 ABC, TDF, AZT, 3TC None   I5V, K22R, K43R, K82R, K104R, M138S, Y162H, F227Y, D250E, I251V, S272P, E297D, I329V, G334D, H335N, I341V, E344G, I357V, E413D R20K, S107T, I108V, Q126P, A134S, V167I, G195D, C232Y, L244I, Q248E, Y317H, S332D 
20080511 20080511 ABC, AZT, 3TC None  A101P I5V, K22R, K104R, M138A, Y162W, K200R, F227Y, T237N, I251V, S272P, K277R, E322G, I329V, Q330L, G334D, H335N, N404D, E413D, V423I, P435L, R448K, K465R, V468T, V493A I8V, R20K, P51S, S107T, I108V, H121CW, A134S, V167I, G195D, C232Y, L244I, K286R, Y317H, S332D, T426A, G431K, D432E, K463R, V481A, R483A, L486I, N515S 
20080618 20080618 TDF, 3TC None K70N, M184V  P1L, I5V, T11E, K22R, K104R, V111I, D123E, M138A, K200R, F214L, F227Y, Q228H, D250E, I251V, Y271H, S272P, K277R, I329V, G334D, H335N, E344G, I357V, T397I, E413D, I434L, A437V, V468K, V493A R20K, S107T, I108V, A134S, V167I, L180I, G195D, C232Y, L244I, I270L, R281K, K307R, Y317H, S332N, T426A, K463R, V481A, R483M, A487T, I496V 
20080869 20080869 ABC, AZT, FTC, 3TC None K70N, M184V  I5V, V10VI, T11M, K22R, K104R, M138A, F227Y, Q228H, D250E, S272P, K277R, I329V, G334D, H335N, I341IV, E344EG, K347KR, I357V, N404D, E413D R20K, V83VA, S107T, I108V, A134S, P176M, L180I, G195D, C232Y, L244I, I270L, K307R, Y317H, S332D, E345ED, T426A 
20081032 20081032 ABC, AZT, 3TC None K65R, Y115F, Q151M, M184V  I5V, K22R, T58S, K64R, N69S, D86E, K104R, V111I, D123DN, Y162H, K200R, F214L, F227Y R20K, V83I, I90V, S107T, I108V, H121D, M138I, V167I, L180I, G195D, C232Y 
20081313 20081313 None None   I5V, K22R, K43R, K64R, D86E, K104R, H121Y, D123G, M138A, G211N, F227Y, Q228R, D250E, S272P, I329V, G334D, H335N, I341V, E344G, N359H, V365I I8V, R20K, S107T, I108V, A134S, V167I, I189V, G195D, C232Y, L244I, Y317H, S332D, I348V 
20090342 20090342 None None   V10I, T11M, K22R, K28KR, K64R, D86E, K104R, M138A, Y162H, K173R, D192N, F227Y, Q228R, K249R, D250E, I251V, S272P, I329V, G334D, H335N, E344G, I357V, E394EK, E396D, E413D, A437T, K465R, V493A, R516RK, K527R, E529ED, V531I R20K, K68Q, S107T, I108V, A134S, V167I, G195D, D199E, C232Y, L244I, R281K, Y317H, S332D, V417VIM, T426AV, D432DE, K463R, V481A, R483A, A487T 
ITG12880 195603 None None I75M  I5V, V10I, T11M, K22R, K35KT, K64R, K104R, V111I, M138A, Y162H, M164I, K200R, F227Y, Q228H, D250N, I251V, S272P, K277R, I329V, G334D, H335N, E344G, I357V K9NS, R20K, E42V, T60V, I108V, L132I, A134S, I145T, V167VI, P176*Q, V178T, L180I, G195D, L212I, S215T, C232Y, L244I, K307R, Y317H, S332D 
ITG17659 195911 ABC, D4T, 3TC None M184V  K82R, M138A, A158T, Y162F, D250E, S272P, Q333E, G334D, H335N, I357V, I375V P51S, S107T, I108V, A134S, V167I, C232Y, K307R, S311G, Y317H, T360A 
ITG24071 ITG_24071 D4T, 3TC None   V10I, T11TA, K22R, I31V, K43R, T58S, K64R, D86E, V111I, M138A, Y162H, Q166R, K200R, D250E, S272P, I329V, Q330H, G334D, H335N, E344G, I357V V2VI, I8IV, R20K, P51S, I90V, S107T, I108V, A134S, V135I, V167I, G195N, C232Y, L244I, V263VG, V293I, K307R, Y317C, S332D 
ITG2545 196207 None None   D17E, K22R, K28R, K43R, K104R, V111I, D123E, V135T, M138A, K200R, D250E, I251V, S272P, K277R, I329V, Q330H, G334D, H335N, I341IV, E344G, K347R, I357V, E396D R20K, P51S, V83A, I90V, S107T, I108V, A134S, Q166QK, V167I, G195D, V202I, C232Y, L244I, M287ML, E305EK, Y317C, S332D, G384GE 
ITG28175 ITG_28175 ABC, D4T None I75M, Y115F, Q151M, M184V  I5V, T11M, K22R, K35T, K82R, K104R, V111I, M138A, Y162H, P176Q, K200R, F227Y, Q228H, D250N, I251GV, S272P, K277R, I329V, G334D, H335N, E344G, I357V R20K, E42V, T60V, I108V, L132I, A134S, I145T, M164V, V167I, V178T, L180I, G195D, L212I, S215T, C232Y, L244I, K307R, Y317H, S332D 
V060880 V06-0880 None None   I5V, K22R, K64R, K104R, M138A, P176Q, F227Y, Q228R, D250E, I251V, S272P, I329V, G334D, H335N, I341V, E344G, N359H, V365I, R385RQ, N404D, E413D, V417I, V458I, K465R, V493A R20RK, P51S, Y56F, S107T, I108V, A134S, V135VI, V167I, L180I, G195D, C232Y, L244I, R281K, Y317H, S332D, T426A, G431K, V481A, R483A, A487T, I496V 
V061132 194310 None None   I5V, L21I, K22R, T27S, K28R, K66R, K102E, K103R, K104R, L109I, E122P, D123E, M138A, E169D, P176S, I179T, K200R, G211N, L212M, D218E, D250E, I251V I8AV, T11K, R20K, E32L, N57NS, I90V, I108V, H121D, A134S, V135I, E139ED, T163S, Q166K, L180I, T194S, G195D, V201A, L203S, C232Y, T237K, L244I, Q248E 
V061139 V06-1139 None None   I5V, K28KR, I31IV, K35KR, T58S, K82R, D123N, R125K, Y162H, Q228H, D250E, S272P, G334D, H335N, G436D, F440Y, V468I, V493A, R516K, I517V, E524D K13M, S107T, I108V, H121D, Q126K, A134S, L180I, C232Y, M287L, K307R, Y317C, E324D, S332N, Q333L, A369T, V481A, R483A, N515S 
V063475 V06-3475 ABC, TDF, 3TC None K65R, Q151M, S215ST  I5V, K22R, T27S, K28KR, K35R, D86E, K104R, V111I, M138A, D218DE, D250E, I251V V2I, R20K, N69T, I90V, S107T, I108V, A134S, V135I, V167I, G195D, E207EQ, C232Y, L244I 
V063553 V06-3553 TDF, 3TC None M184MIV  T27TS, K28R, K64R, M138A, K173KR, D250E, I251R M41MI, E49EG, I63L, M73MI, R105RK, S107T, I108V, A134S, G141GR, G195GS, C232Y, E233EK, L244LI 
V071200 V07-1200 None None   K22R, T58S, K64R, K82R, D86E, K103R, D123DN, M138A, A158T, K200R, D250E, S272P, G334D, H335N, I357V, F440Y V2I, S107T, I108V, A134S, C232Y, K307R, Q333T, T360A, N363NK 
V071737 V07-1737 Unknown Unknown K70S, M184V, S215Y I181V T11S, K35R, K40R, V111I, T163A, K249E, D250E, S272P, I274V, K277R, R284K, G334D, H335N R20K, S107T, I108V, A134S, I187L, C232Y, L244I, K307KR, Q312QL, Y317H, S332N, Q333L, E345D 
V074155 V07-4155 None None Q151M  K22R, K28R, K43R, K82KR, D86E, K104KR, M138A, F214L, D218E, D250E, I251V, S272P, K277R, I329V R20K, K40KE, S107T, I108V, A134S, V167I, G195DN, C232Y, L244I, Y317C, S332D 
V080553 V08-0553 None None   V10I, T11M, K43R, K64R, K82R, K104R, V111I, M138A, P176Q, K200R, G211S, F227Y, Q228H, D250E, I251V, S272P, K277R, I329V, G334D, H335N R20K, Y56F, S107T, I108V, A134S, L180I, G195D, C232Y, L244I, K307R, Y317H, S332D, E345D, T360A 
V082661 196310A None None  I181V L21I, K22R, T27S, K66R, K102E, K103R, K104R, E122P, M138A, E169D, I179T, E197EK, K200R, G211D, D218E, Q228K, D250E K4R, I8V, T11K, R20K, E32L, I90V, S107T, I118V, H121D, A134S, V135I, R165G, Q166K, P176D, L180I, I189V, T194S, G195D, L212I, C232Y, T237K, L244I, Q248E, I251S 
V086011 V08-6011 D4T, 3TC None M184V  K66KR, K82R, M138A, K200KR, D250E, I251V, S272P, K277R, G334D, H335N S107T, I108V, H121D, E122EK, A134S, V201A, L203M, E207EGQR, C232Y, L244I, K307KR, Y317H 
V086050 V08-6050 ABC, AZT, 3TC None   D17E, K64R, K82R, D123N, M138A, Y162H, D250E, S272P, G334D, H335N R20K, I63V, S107T, I108V, A134S, T163M, V167I, V178I, V201A, C232Y, L244I, I270L, Y317C, S332G 
V086051 V08-6051 AZT, 3TC None I75IM, M184V I181V I5V, L21I, K22R, T27S, K35KR, T60TI, K66R, F87L, K102E, K104R, E122P, M138A, R165A, E169D, I179T I8V, T11K, R20K, E32L, L47LI, I90IV, K103KM, S107T, I118V, H121D, A134S, T163S, Q166KR, P176N, L180I, I189V, R193M 
V086052 V08-6052 None None  F227L I5V, T58S, H121C, M138A, I145M, K200R, Q228R, E233D, D250E, S272P, A327V, G334D, H335N I8T, S107T, I108V, A129T, A134S, V167I, C232Y, V293I, K307R, Y317C, E345D, I348V, T360A 
V086119 V08-6119 None None   I5V, K22KR, K28KR, K82R, D86DE, M138A, D250E, I251V, S272P, E291EK, E297ED, Q312QR, I329V, G334D, H335N R20K, L21Q, S107T, I108V, H121D, E122EK, A134S, G195GDNS, C232Y, L244I, E292EK, E305EK, K307KR, Y317H, E345D 
V086120 V08-6120 None None M184V I181V K35R, K82R, H121Y, Y162YH, P176S, I179L, L196LM, K200R, D250E, I251V, S272P, G334D, H335N, N359H R20K, S107T, I108V, A134S, M138V, V167I, L180I, C232Y, V263I, K307R, Y317H, E322ED, E345ED 
V086121 V08-6121 None None  F227L K22R, K35R, K102E, K104R, E122P, M138A, E169D, P176S, G211D, L212M, D218E, Q228R, D250E, I251IV, Y271F, S272P, L279I, T290S, E304Q, S311E, Y317S, E322G, K323E, E324P, I329V, G334A, H335N, E344G, I348T, I357V V2M, I8V, T11K, R20K, E32L, I90V, S107T, I108V, I118V, H121D, A134S, T163S, R165G, Q166K, V167I, L180I, I189V, T194S, G195D, L203S, C232Y, T237K, L244I, Q248E, A268S, I270L, R281K, Q320KR, S332N, Q333L, E345N 
V086122 V08-6122 None None  F227L K22R, K35R, K102E, K104R, E122P, M138A, E169D, P176S, G211D, L212M, D218E, Q228R, D250E, I251IV, Y271F, S272P, L279I, T290S, E304Q, S311E, Y317S, E322G, K323E, E324P, I329V, G334A, H335N, E344G, I348T, I357V V2M, I8V, T11K, R20K, E32L, I90V, S107T, I108V, I118V, H121D, A134S, T163S, R165G, Q166K, V167I, L180I, I189V, T194S, G195D, L203S, C232Y, T237K, L244I, Q248E, A268S, I270L, R281K, Q320KR, S332N, Q333L, E345N 
V086123 V08-6123 None None   I5V, T11E, L21I, K22R, T27S, K28R, K35R, K64R, D86E, K102E, L109I, E122P, M138A, E169D, P176S, K200R, G211D, L212M, D218DE, Q228R, D250E, I251V, Y271F, S272P, K277R, L279I, E304Q, S311E, Y317S, E322G, E324P, I329V, G334A, H335N, E344G, K347R, I357V I8V, R20K, E32L, P51S, I90V, S107T, I108V, H121D, A134S, V135I, T163S, Q166K, L180I, T194S, G195D, L203S, C232Y, T237K, L244I, Q248E, I270L, R281K, Q320K, K323V, S332N, Q333L, E345D 
V086124 V08-6124 None None   I5V, K22KR, K28KR, K82R, M138A, D250E, I251V, S272P, I329V, G334DEKN, H335N R20K, L21Q, S107T, I108V, H121D, E122EK, A134S, G195GDNS, C232Y, L244I, K307KR, Y317H, E345D 
V086127 V08-6127 None None   I5V, P7S, E39Q, T58S, K64KR, M138A, A158T, Y162H, K173KR, D250E, S272P, R284K, G334D, H335N, I357V S107T, I108V, A134S, V135I, Q166K, C232Y, Y317C 
V086130 V08-6130 None None M184MV  K64KR, K82KR, M138A, K200KR, D250E, I251IT, Y271YH, S272P, I329IV, Q333QE, G334D, H335N R20K, S107T, I108V, H121HCRY, A134AS, V167I, G195D, C232Y, L244I, Y317CR, S332SN 
V086136 V08-6136 None None  F227L I5V, P14A, K82R, E122P, R125K, M138A, Y162F, T163I, D250E, I251T, S272P, H278KN, G334D, H335N, Q336QP V2I, S107T, I108V, H121D, A134S, V201A, C232Y, T253TA, K307R, Y317C, Q343QP, E345D, V351VI 
V086139 V08-6139 None None   I5M, K28R, E32G, K35R, T58S, K64R, N69S, H121Y, R125K, M138A, I145V, D250E, I251V, S272P, Q333R, G334D, H335N V2I, S107T, I108V, A134S, C232Y, I270L, Y317C