<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Abdissa (2014)
Title Drug resistance in HIV patients with virological failure or slow virological response to antiretroviral therapy in Ethiopia.
Citation BMC Infect Dis
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 28
NumPts 14
Subtype C

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
146 146_BL None None   V35T, E36A, T39E, A98S, K122E, D123G, A158S, K173A, T200A, Q207E, R211K, V245Q, A272P, K277R, L283I, T286A, E291D, V292I, I293V  
  146_FL TDF, 3TC EFV   V35T, E36A, T39E, A98S, K122E, D123G, A158S, K173A, T200A, Q207E, R211K, V245Q, A272P, K277R, L283I, T286A, E291D, V292I, I293V  
157 157_BL None None   V35T, T39E, A98S, K122E, D123S, I135R, K173A, Q174K, D177E, T200E, Q207E, R211K, V245Q, S251T, A272P, I293V, P294AT, D324DE K13KE, E29E* 
  157_FL TDF, 3TC EFV K65KR, D67G, M184I G190Q V35T, T39E, V90I, A98S, K122E, D123S, I135R, K173A, Q174K, D177E, T200E, E203EK, Q207E, R211K, V245Q, S251T, A272P, I293V, P294T, E297EK, D324E  
213 213_BL None None   V35T, E36M, T39E, S48T, K122E, D123G, K173A, D177E, G196K, T200A, I202V, E204D, Q207AE, R211K, V245Q, A272P, K277KR, E291D, V292I, I293V, K311KR, D324E  
  213_FL TDF, 3TC NVP  Y181C V35T, E36M, T39E, S48T, K122E, D123G, K173A, D177E, G196K, T200A, I202V, E204D, Q207A, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, K311R, D324E  
243 243_BL None None  K103KN V35T, T39E, A98S, K122E, D123S, I135R, K166KR, K173A, D177E, I178ILM, T200A, I202V, Q207E, R211RK, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
  243_FL AZT, 3TC NVP  K103KN V8VI, V35T, T39E, A98S, K122E, D123S, I135R, K173A, D177E, I178ILM, T200A, I202V, Q207E, R211RK, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
25 25_BL None None  A98G T27S, V35T, E36A, T39E, S48T, K122E, D123G, I135V, S162A, K173KAET, D177E, I178M, G196K, T200A, I202IV, Q207R, R211EK, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, K311R  
  25_FL TDF, 3TC EFV   V35K, E36A, T39E, S48T, K122E, D123GS, K173AT, D177E, G196K, T200A, I202V, Q207A, R211K, V245Q, E248DN, A272P, K277R, L279M, T286A, V292VI, I293V, V317A, I326IV, Q334QDEH  
269 269_BL None None  V179D T27S, V35T, E36A, T39E, S48T, V90I, K122E, D123S, A158S, S162H, K173A, D177E, E194D, I195IV, G196R, T200A, Q207E, R211RK, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, D324E  
  269_FL TDF, 3TC EFV  V179D T27S, V35T, E36A, T39E, S48T, V90I, K122E, D123S, A158S, S162H, K173A, D177E, E194D, I195IV, G196GR, T200A, Q207DE, R211RK, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, D324E Q91QE 
300 300_BL None None  K103N, V106VM V35T, E36A, T39E, A98S, I135V, Q145C, K173I, D177E, T200A, Q207E, R211K, V245Q, E248D, D250E, S251N, A272P, K277R, T286A, E291D, V292I, I293V, P294T  
  300_FL TDF, 3TC EFV  K103N V35T, E36A, T39E, A98S, D123E, I135V, Q145C, K173I, D177E, T200A, Q207E, R211K, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, P294T  
301 301_BL None None  V179VD K20R, V35IM, E36EA, T39E, S48T, K122E, D123S, I135T, A158S, D177EG, V189VI, T200A, E203EG, Q207E, R211RK, F214L, V245Q, K249Q, A272P, K277KR, T286TA, E291D, V292I, I293V, E308EK, K311R, V317VA  
  301_FL TDF, 3TC EFV K65KR V106M, V179D K20R, V35IM, E36EA, T39E, S48T, S105SA, K122E, D123S, I135T, A158S, D177E, T200A, Q207E, F214L, V245Q, K249Q, A272P, K277KR, E291D, V292I, I293V, K311R, V317A  
314 314_BL None None   V35T, T39DN, V60VI, A98S, K122KE, A158S, K166KR, K173A, Q174QK, D177E, T200A, Q207E, R211K, V245Q, K249Q, A272P, K277R, L279M, T286A, E291D, I293V  
  314_FL TDF, 3TC EFV   V35T, T39DN, V60VI, A98S, K122KE, A158S, K173AV, Q174QK, D177E, T200A, Q207E, R211K, V245Q, K249Q, A272P, K277R, L279M, T286A, E291D, I293V  
339 339_BL None None   V35T, E36EA, T39E, S48T, V60VI, V90VI, K122E, D123S, K173A, Q174K, D177E, T200TA, Q207E, R211RK, V245Q, E248N, D250E, A272P, K277R, L279M, T286A, E291D, V292I, I293V  
  339_FL TDF, 3TC NVP M184I A98G, Y181C V35T, T39E, S48T, V90VI, K122E, D123S, K173A, Q174K, D177E, T200A, E203K, Q207E, R211K, V245Q, E248N, D250E, A272P, K277KR, L279M, T286A, E291D, V292I, I293V, T296A  
346 346_BL None None  K101E V35T, T39DE, K122E, D123S, I135R, I142V, K173AT, D177EG, T200A, E204EK, Q207X, R211RK, V245Q, A272P, T286A, E291D, V292I, I293V, I329L, Q334QH  
  346_FL AZT, 3TC NVP M184V K101E, G190A V35T, T39E, K122E, D123S, I135K, I142V, K173T, D177E, T200A, E204K, Q207D, R211K, V245Q, A272P, T286A, E291D, V292I, I293V, I326V, I329L W239WR 
357 357_BL None None   V8VI, K32E, V35RT, E36A, T39DEKN, K49KR, V60VI, K122E, D123DG, I135R, A158S, K173A, Q174K, D177E, I178M, V179I, T200A, Q207E, R211RK, V245Q, A272P, K281KR, E291D, V292I, I293V, D324E  
  357_FL TDF, 3TC EFV   V8I, K32E, V35R, E36A, T39E, K102KQ, K122E, D123DG, I135R, A158S, K173A, Q174K, D177E, I178M, V179I, T200A, Q207E, R211RK, V245Q, A272P, K281KR, E291D, V292I, I293V, D324DE  
360 360_BL None None   V35T, E36EA, T39AD, S105A, A158S, K173T, Q174K, D177E, V179I, G196E, T200A, Q207E, R211RK, V245Q, E248ED, A272PQ, K275KQ, T286TA, E291D, V292I, I293V, V317A  
  360_FL TDF, 3TC NVP  V106M V35T, E36EA, T39AD, S105A, A158S, K173T, Q174K, D177E, V179I, G196E, T200A, Q207E, R211REGK, V245Q, E248ED, A272P, K275KQ, T286TA, E291D, V292I, I293V, V317A, D324DE  
9_BL None None  K103N K32R, V35I, E36EA, T39E, S48T, V90VI, A98S, D121H, K122E, D123S, A158S, K173A, Q174K, D177E, I178IL, T200A, Q207E, R211K, V245Q, E248N, A272P, E291D, V292I, I293V, P294T  
  9_FL TDF, 3TC EFV M184I K103N, P225H K32R, V35IM, T39K, S48T, V90I, A98S, D121H, K122E, D123S, A158S, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, V245Q, E248N, A272P, E291D, V292I, I293V, P294T