<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Van Tran (2016)
Title A strong association of human leukocyte antigen-associated Pol and Gag mutations with clinical parameters in HIV-1 subtype A/E infection.
Citation AIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 359
NumPts 359
Subtype CRF01_AE

 

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Page 1   listing Isolate 1 to Isolate 100 from Total 359 Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
VI-004 VI-004 None None   E6D, K11T, V35I, E36K, T39E, S68G, K122E, D123S, S162C, K173T, Q174K, D177E, I178M, T200A, Q207S, R211S, F214L, K238R, V245E, E248D, T286A, E291D, I293V, K311Q, E312T, I329V, G335D, M357K, G359S, K366R, A371V, K388R, K390R, E399D, A400T, T403R, E432D, D471E, Q480H, L491P, K512R, L517I, S519N, Q524G, K527R, A534S, A554N, K558R  
VI-006 VI-006 None None   E6D, V35T, T39L, K122E, D123S, S162C, K173T, Q174K, D177E, T200A, Q207S, R211S, K238R, V245E, A272AP, T286TA, E291D, V292I, I293V, E312T, S322A, I326V, I329V, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, D460N, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
VI-012 VI-012 None None   E6D, K11T, V35T, T39N, K122E, D123S, S162C, K173I, Q174K, D177E, I178IM, Q207K, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E297K, A304E, E312T, I326V, I329V, G335D, P345Q, M357R, G359S, K366R, A371V, V381VI, K390KR, K395R, A400T, T403M, E432D, N447S, R461K, Q464K, K465R, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
VI-022 VI-022 None None   E6D, K11KR, E28K, K32E, V35T, T39K, S162C, K173T, Q174K, D177DE, Q207S, R211S, K238R, V245E, K281R, T286TA, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369TS, A371V, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
VI-023 VI-023 None None   E6D, K11T, E28K, K32E, V35T, T39K, S162C, K173T, Q174R, Q207S, R211S, K238R, V245E, V276VI, K277KR, K281R, T286TA, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K395R, A400T, T403M, E432D, N447S, V467VI, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S G231GR, W410W*, G456GE 
VI-025 VI-025 None None   E6D, K11T, V21VI, V35T, T39K, K122E, D123S, S162CY, K173I, Q174K, D177E, Q207S, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E297A, R307K, E312T, V317T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A400T, T403M, E432D, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, E529D, V531I, A534S  
VI-028 VI-028 None None   E6D, K11T, V35T, K122E, D123N, I135T, S162C, K173I, Q174K, D177E, I178M, T200A, E204K, Q207D, R211S, K238R, V245E, K249Q, L283I, I293V, L295M, E312T, I326V, G335D, Y342F, M357R, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
VI-038 VI-038 None None   E6D, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177G, Q207S, R211S, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E297V, E312T, D324E, I326V, I329V, G335D, P345Q, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, L469I, D471E, K476Q, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S  
VI-046 VI-046 None None   E6D, K11T, V35T, T39EK, V106VI, K122E, D123NS, S162C, K173I, Q174K, D177E, I178M, Q207S, R211S, K238R, V245E, I274IV, K281R, T286A, E291D, V292I, I293V, E312T, D324E, I326IV, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432ED, N447NS, V458I, D471E, Q480H, L491S, A502AV, K512R, E514D, L517V, S519N, Q524E, A534S  
VI-050 VI-050 None None   E6D, K11T, K32E, V35T, E36A, T39A, K104R, K122E, D123N, I135R, S162C, K173I, Q174K, D177E, Q207NS, R211S, F214L, K238R, V245E, E248D, K275KQ, T286A, E291D, V292I, I293V, E312T, I329V, G335D, M357K, R358RG, G359S, K366R, A371V, A400T, T403R, E432D, L452I, D460DN, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554K  
VI-054 VI-054 None None   E6D, K11T, V111I, K122E, D123N, S162H, K173I, Q174K, D177E, V179I, Q207S, R211S, F214L, K238R, V245E, E248D, K277R, T286A, I293V, E312T, G335D, A355T, M357Q, G359S, K366R, A371V, K390R, K395R, A400T, T403R, E432D, N447S, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554N  
VI-062 VI-062 None None   E6D, K11T, V35T, T39N, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207S, R211S, V245E, K281R, T286A, E291D, V292I, R307K, E312T, I326V, I329V, G335D, E344*, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, V466I, S468T, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
VI-073 VI-073 None None   E6D, K11T, V35T, D86E, K122E, D123S, S162Y, K173I, Q174K, D177E, V179I, Q207S, R211S, K238R, V245E, K281R, T286TA, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A400T, T403M, E432D, N447S, V466I, T470N, D471E, Q480H, L491S, K512R, E514D, L517I, S519N, Q524E, A534S, A554S N54S 
VI-075 VI-075 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, K277R, T286A, A288S, V292I, I293V, E312T, I329V, G335D, P345Q, F346S, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554Q  
VI-079 VI-079 None None   K11T, V21I, E28K, K32E, V35T, K122E, D123S, S162C, K173A, Q174K, D177E, T200L, Q207A, R211N, K238R, V245E, T286A, I293V, E312T, I329V, G335D, M357K, G359S, K366R, A371V, S379SG, A400T, T403M, E432D, V435VI, N447S, T470TA, D471E, Q480H, H483Q, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554Q, K558R  
VI-080 VI-080 None None   E6D, K11T, V35T, T39DN, T69N, K122E, D123S, I142AV, S162C, K173T, Q174K, D177E, I178M, T200A, Q207N, R211K, L228X, K238R, V245E, E248D, A272AS, T286A, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, E432D, N447S, D471E, K476R, Q480H, L491PS, K512R, E514D, L517V, S519N, Q524E, A534S, K550KR, A554S, I556V, K558R  
VI-082 VI-082 None None   E6D, V35T, T39K, K43E, V60I, K122E, D123S, I135V, E169D, K173M, Q174K, D177E, V179I, T200R, Q207A, R211H, K238R, V245Q, T286A, E291D, V292I, I293V, E312N, I326V, G335D, M357K, G359S, K366R, A371V, A376V, K388R, K390R, A400T, T403M, E432D, N447S, L452Q, D460N, D471E, Q480H, H483Y, L491S, L517V, S519N, Q524E, K530R, A534S, A554S  
VI-087 VI-087 None None   E6D, K11T, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207S, R211S, K238R, V245E, A272P, T286TA, E291D, V292VI, I293V, E297EA, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E404D, E432D, N447NS, V466T, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S  
VI-090 VI-090 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207K, R211S, K238R, V245E, K281R, T286A, E291D, I293V, K311KQ, E312NT, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376S, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, E529D, A534S, A554S  
VI-093 VI-093 None None   E6D, K11T, V35T, T39E, S68G, K122E, D123NS, I135R, S162C, K173I, Q174K, D177E, Q207NS, R211S, K238R, V245E, T286A, I293V, E312T, I329V, G335D, M357K, G359S, K366R, A371V, T377LP, S379G, A400T, T403M, E432D, N447S, D471E, Q480H, H483Y, L491S, K512R, L517I, S519N, Q524E, A534S, K558R  
VI-094 VI-094 None None   E6D, V35T, T39Q, K122E, D123S, S162C, K173I, Q174K, D177E, G196E, T200A, Q207S, R211N, K238R, V245E, T286A, I293V, E312A, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, L517I, S519N, Q524E, A534S, A554L  
VI-100 VI-100 None None   E6D, V35T, T39N, K122KE, D123S, S162C, K173A, Q174K, D177E, E194D, G196E, Q207S, R211S, V245E, V261I, T286A, I293V, T296TA, E312T, G335D, M357K, G359S, K366R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517I, S519N, Q524G, A534S, A554S  
VI-101 VI-101 None None V75VM  E6D, K11A, V35T, T39K, K43E, I50V, K122E, D123S, S162C, T165A, K173R, Q174K, D177E, I178M, Q207S, R211S, V245E, T286A, V292I, I293V, E312N, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, V435A, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S D237DV, K238*R 
VI-110 VI-110 None None   E6D, K11T, E28EK, K32KE, V35T, T39N, K122E, D123N, I142IV, S162C, K173I, Q174K, D177E, I178M, T200A, Q207DGNS, R211NS, K238KR, V245E, T286A, E291D, I293V, K311KT, E312NT, I329V, G335D, M357K, G359S, K366R, A371V, T377L, K390R, A400T, T403M, E432D, N447S, R448K, R461RK, V467VI, D471E, Q480QH, L491S, K512R, L517I, S519N, Q524E, K530I, V531X, Y532H, A534S, L551R, A554S S379SAGT 
VI-113 VI-113 None None   V35T, T39K, K43E, K122E, D123S, T165I, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, A272G, T286A, E291D, V292I, I293V, K311R, E312T, I329V, G335D, M357K, G359S, K366R, A371V, I375V, V381VI, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
VI-115 VI-115 None None   E6D, K11T, V35T, K122E, D123NS, S162C, K173I, Q174K, D177E, I178M, T200E, Q207A, R211S, K238R, V245E, A272P, K281R, I293V, K311R, E312T, I329V, G335D, M357K, G359S, K366R, A371V, T377TI, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483HQ, L491S, K512R, L517I, S519N, Q524E, A534S, D549DN, A554S, V559VG  
VI-117 VI-117 None None   P4H, E6D, K11T, V35T, K104R, K122E, D123S, S162C, K173L, Q174K, N175H, D177K, Q207DGNS, R211S, K238R, V245E, T286A, E291D, V292I, I293V, L310I, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, D471E, Q480H, L491S, I505V, K512R, E514D, L517V, S519N, Q524E, A534S, A554K, K558R K201V 
VI-118 VI-118 None None   E6D, V35T, T39K, K43KR, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, I178M, V179I, T200R, Q207S, R211S, K238R, V245E, K275Q, E291D, I293V, E312T, I329V, G335D, R356RK, M357K, G359S, K366R, A371V, I375V, K390R, K395R, A400T, T403I, E432D, L452KR, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, I542IM  
VI-122 VI-122 None None   E6D, V35T, T39N, K122E, D123S, S162A, T165TI, K173T, Q174K, D177E, I178M, Q207A, R211S, V245EK, A272P, V292I, I293V, L310LI, E312AT, I326MV, I329V, G335D, M357K, G359S, K366R, A371V, T386I, K390R, A400T, T403M, E432D, V435I, Q464K, K465R, D471E, Q480HY, L491S, A508AT, K512R, L517V, S519N, Q524E, V531I, A534S, A554T, I556V  
VI-124 VI-124 None None   E6D, K11T, V35T, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, I178M, Q207S, R211S, K238R, V245E, A272P, E291D, V292I, I293V, E312T, I329V, G335D, F346C, M357K, G359S, K366R, A371V, K390R, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, E514D, L517V, S519N, Q524E, A534S E248E*, K550KE 
VI-125 VI-125 None None   E6D, V35T, T39TA, K122E, D123S, T139A, S162C, K173I, Q174K, D177E, I178M, T200A, Q207GR, R211S, F214L, V245E, E248D, K275S, T286A, E291D, V292I, I293V, E312N, D324E, I329V, G335D, P345T, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403R, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, K527R, A534S, A554N  
VI-126 VI-126 None None   E6D, V35T, T39E, K122E, D123S, K173I, Q174K, D177E, G196E, T200A, Q207A, R211S, F214L, K238KR, V245E, T286TA, I293V, I326V, I329V, G335D, Y342YF, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E404D, E432D, N447S, V466A, V467VI, S468H, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554S, K558KR E312IKM 
VI-129 VI-129 None None   E6D, K11T, E28K, K32KE, V35T, T39K, E40D, K122E, D123N, S162C, K173I, Q174K, D177E, I178LM, V179I, Q207S, R211S, V245E, K275Q, V276I, T286A, I293V, E297K, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390R, K395R, A400T, T403M, E432D, N447S, K465R, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, K530KR, A534S, A554T  
VI-134 VI-134 None None   E6D, K11T, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, Q207S, R211S, V245E, K281R, T286A, E291D, V292I, I293IV, E312I, I329V, G335D, M357K, G359S, K366R, A371V, V381I, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, K527N, A534S, A554S  
VI-139 VI-139 None None   I5V, E6D, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, Q207S, R211N, V245E, K281R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, Q334P, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, V435I, N447S, E449D, D471E, Q480Y, H483Y, L491S, K512R, E514D, L517V, S519N, Q524E, K527N, A534S, A554S  
VI-144 VI-144 None None   E6D, K11T, V35I, V111I, K122E, D123S, S162C, K173I, Q174K, D177E, Q207S, R211S, F214L, K238R, V245E, E248D, V276I, T286A, E291D, V292I, I293V, E312T, I329V, G335D, P345PQ, A355AG, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403R, E432ED, N447S, D460N, R461RK, D471E, T477TA, Q480QH, L491PS, K512R, E514ED, S519N, Q524E, A534S, A554N F61FY, L517EIKV 
VI-145 VI-145 None None   K11KT, V35T, V60VI, S68G, K122E, D123N, I135IV, S162C, T165IV, K173T, Q174K, D177E, Q207A, R211S, V245E, K249Q, T286A, I293V, E312T, I326V, I329V, G335D, M357K, G359S, A371V, K390R, A400T, T403M, E404ED, E432D, N447S, L452I, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S T39HKNQ, G541GE, I542IKMN, A554IN 
VI-160 VI-160 None None   E6D, K11T, V35T, T39DN, T69TN, L100*, K122E, D123N, I142V, S162C, K173KR, Q174K, D177E, I178M, R199RK, Q207A, R211S, V245E, K275R, T286A, E291D, V292I, I293V, E312T, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Y, L491S, K512R, L517T, S519N, Q524E, E529D, A534S, V548A, A554S E29EK, M41MI, E42K, E79K 
VI-166 VI-166 None None   E6D, K11T, E28EK, K32KE, V35T, T39D, D121H, K122E, D123NS, I142V, S162C, K173T, Q174K, D177E, I178IL, T200TA, Q207S, R211S, K238KR, V245E, A272P, I274IV, E291D, V292I, I293V, E312T, S322A, I326IV, I329V, G335D, M357K, G359S, A371V, K390R, A400IL, T403TM, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
VI-175 VI-175 None None   K11T, K20R, V35T, T39K, K122E, D123S, S162C, K173V, Q174K, D177E, Q207S, R211GS, V245E, I293V, E312T, I326V, I329V, G335D, M357K, G359S, A371AV, K390R, A400T, T403MV, E432D, V435VA, G436E, D471E, Q480H, H483HY, L491S, K512R, S515L, L517V, S519N, Q524E, A534S, A554S  
VI-179 VI-179 None None   E6D, K11T, V35T, T39K, K43E, R83K, T107S, K122E, D123S, S162C, K173I, Q174K, D177E, Q207T, R211S, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, R356RK, M357K, G359S, K366R, A371V, K390R, A400T, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554Q  
VI-181 VI-181 None None   E28K, V35T, T39N, V60I, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207S, R211S, K238R, V245E, K281R, T286A, E291D, V292I, I293V, E297A, E312T, V317A, S322L, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, K527R, E529D, A534S, A554T  
VI-193 VI-193 None None   E6D, V35T, T39E, S68G, T69N, K122E, D123S, I135T, S162Y, K173I, Q174K, D177E, Q207S, R211S, K238R, V245E, T286A, E291D, V292VI, I293V, E297KT, A304E, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T377Q, A400T, T403M, P421PL, E432D, N447NS, D471E, Q480H, L491PS, K512R, E514D, L517V, S519N, Q520QR, Q524E, A534S, A554Q, K558R  
VI-194 VI-194 None None   E6D, K11T, V35T, T39K, K43E, D121Y, K122E, D123S, S162C, K173I, Q174K, D177E, T200I, Q207N, R211S, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312T, D324E, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376S, V381I, K390R, A400T, T403M, E432D, V435A, L452Q, D471E, Q480H, A485T, L491S, K512R, E514D, S515L, L517I, S519N, Q524E, A534S, A554S  
VI-196 VI-196 None None   E6D, K11T, V35T, T39E, V106I, D121H, K122E, D123S, S162C, K173A, Q174R, D177E, T200A, Q207S, R211S, K238R, V245E, E291D, V292I, I293V, E312A, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, V435I, N447S, R461K, D471E, Q480H, L491S, K512R, E514D, L517I, S519N, Q524E, A534S, A554S G504R 
VI-199 VI-199 None None   E6D, V35T, T39N, V60I, D121H, K122E, T139A, I142V, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, T286TA, E291ED, I293V, K311Q, E312NT, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403TIM, E432D, N447S, L452I, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
VI-202 VI-202 None None   E6D, E28K, K32E, V35T, T39K, V60I, K122E, D123S, I135T, S162CY, K173R, Q174K, D177E, I178M, V179I, I202IV, Q207S, R211S, K238R, V245E, T286TA, E291D, V292VI, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T386I, K390R, A400L, T403M, E432D, V435VA, N447S, D471E, Q480H, H483Y, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, E546D, V548G, D549E, K550X, V552VI, I556V, R557T N545NY, G555GR 
VI-206 VI-206 None None   E6N, K11T, V35T, T39K, G112A, K122E, D123N, I142V, S162C, K173I, Q174K, D177E, I178LM, G196E, Q207S, R211S, K238R, V245E, K275Q, K277R, T286A, E291D, V292I, I293V, E297V, E312T, D324DE, I326V, I329V, G335D, P345PQ, M357K, G359S, K366R, A371V, T377Q, K390R, A400T, T403M, N447S, R461K, D471E, Q480H, L491S, K512KR, L517V, S519N, Q524E, A534S, A554K, K558R  
VI-210 VI-210 None None   E6D, V35T, T39Q, K122E, D123S, S162C, K173I, Q174K, D177E, G196E, T200AE, Q207S, R211N, K238R, V245E, I293V, E312A, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, L517I, S519N, Q524E, A534S, A554L  
VI-217 VI-217 None None   E6D, K11T, V35T, T39K, K122E, D123S, S162C, K173R, Q174E, D177E, T200A, E203D, Q207N, L210*, R211N, W212G, K238R, V245Q, T286A, E291D, V292I, I293V, E312T, I326V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, V435A, N447S, E449D, L469I, D471E, Q480H, L491S, K512R, E514D, S519N, Q524E, E529D, A534S, A554S  
VI-219 VI-219 None None   E6D, K11T, V35T, T39EK, V60I, T107S, K122E, D123S, S162C, K173I, Q174K, D177E, V179I, T200A, Q207A, R211S, K238R, V245E, A272P, T286A, A288T, E291D, V292I, I293V, E312T, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395KR, A400T, T403M, E432D, V435I, N447S, D471E, Q480H, H483Y, L491S, K512R, E514D, L517V, S519N, Q524E, K527R, A534S, A554Q  
VI-223 VI-223 None None   E6D, V8I, K11T, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, Q207E, K238R, V245E, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, T470A, D471E, T477A, Q480H, H483Y, K512R, E514D, L517V, S519N, Q524E, K530Q, A534S, A554S  
VI-225 VI-225 None None   E6D, V35T, T39N, K122E, D123S, I135R, I142V, S162C, K173A, Q174K, D177E, Q207KN, R211NS, K238R, V245E, S251C, A272AP, V276VI, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D460N, D471E, Q480H, H483L, S489A, G490GE, L491S, K512R, E514D, L517LV, S519N, Q524E, A534S, A554S  
VI-228 VI-228 None None   E6N, K11T, V35T, T39N, K122E, D123S, S162C, D177E, Q207K, R211S, K238R, V245E, K281R, T286A, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, D460N, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S, K558R  
VI-231 VI-231 None None   E6D, V35T, T39E, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, T200A, Q207E, R211K, K238R, V245E, K249R, S251H, A272P, T286A, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, D364E, K366R, A371V, K390R, A400I, T403R, E432D, N447S, L452Q, V466I, D471E, Q480H, H483Y, L491S, K512R, S515A, L517V, S519N, Q524E, A534S, A554Q  
VI-238 VI-238 None None   E6D, K11AT, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, L193LF, E194D, Q207S, R211S, K238R, V245E, K281R, T286A, E291D, V292VI, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, I375IV, K390R, K395KR, A400T, T403M, K431Q, E432D, N447S, V458I, D471E, Q480H, H483Y, L491S, K512R, E514D, L517V, S519N, Q524E, E529D, A534S, A554S  
VI-239 VI-239 None None   I5IV, V8VI, K11T, V35T, T39N, K122E, D123S, S162C, K173R, Q174K, D177E, I178IM, T200TA, Q207S, R211S, K238R, V245E, K281KR, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, I375V, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, E514D, L517V, S519N, Q524E, E529D, A534S, V536I, A554L  
VI-242 VI-242 None None   E28K, K32E, V35T, T39K, V60I, K102KR, T107TS, K122E, D123S, S162C, K173I, Q174K, D177E, V179I, T200A, Q207N, R211S, V245E, K275R, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Y, L491S, K512R, E514D, L517V, S519N, Q524E, E529D, V531I, A534S, A554S  
VI-243 VI-243 None None   P4S, E6D, K11T, V111I, K122E, D123N, S162Y, K173I, Q174K, D177E, V179I, Q207S, R211S, F214L, K238R, V245E, E248D, T286A, A288AT, I293V, E312T, G335D, M357Q, G359S, K366R, A371V, K390R, K395R, A400T, T403R, E432D, N447S, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, K550KR, A554N  
VI-244 VI-244 None None   E6N, K11T, V35T, T39K, K122E, D123S, I135V, S162C, K173I, Q174K, D177E, I178M, T200A, Q207G, R211S, K238R, V245E, A272P, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A376AT, K390R, A400T, T403M, E432D, N447S, Q464K, D471E, Q480H, L491S, Q509K, L517V, S519N, Q524E, A534S, V548A, A554S A371GV 
VI-245 VI-245 None None   E6D, K11T, V35T, T39K, V118I, K122E, D123N, I135T, I142T, S162G, K173I, Q174K, D177E, Q207N, R211S, F214L, K238R, V245E, T286A, I293V, E312T, I329V, G335D, M357K, G359S, K366R, A371V, A400T, E432D, T459TS, R461K, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
VI-247 VI-247 None None   E6D, K11T, E28EK, K32KE, V35T, T39N, K122E, D123S, S162C, K173T, Q174K, D177E, Q207NS, R211KN, K238R, V245E, K281R, T286A, E291ED, V292VI, I293V, E312N, I329V, G335D, M357K, G359S, A371V, S379G, V381VI, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, G490D, L491X, K512R, E514D, L517V, S519N, Q524E, E529D, A534S, A554S  
VI-248 VI-248 None None   E6D, V35T, T39N, T69S, K122E, D123S, I135T, S162W, K173I, Q174K, D177E, T200A, Q207G, R211S, K238R, V245E, A272P, K281R, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Y, L491S, Q509KT, L517V, Q524E, A534S, V548A, I556V  
VI-251 VI-251 None None   E6D, K11T, V21VI, V35T, T39KN, K43KE, V60VI, K102Q, K122E, D123NS, S162C, K173I, Q174K, D177E, I178IM, E194D, I202IV, Q207GS, R211S, K238R, V245E, I274IV, T286A, E291D, V292I, I293V, E312T, I326IV, I329V, G335D, M357K, G359S, K366R, A371V, V372VI, A376AV, T377X, S379SG, A400T, T403TM, E432D, V435VA, N447S, D471E, Q480H, H483HY, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
VI-254 VI-254 None None   P14S, V35T, T39K, K43Q, K122E, D123S, S162C, K173R, Q174K, D177E, I178M, T200V, Q207A, R211S, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312A, P313T, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, K431R, E432D, V435T, K454R, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, K530R, A534S, A554K, K558R  
VI-258 VI-258 None None   E6D, K11T, V35T, T39I, K122E, D123S, S162C, K173I, Q174K, D177E, I178IM, T200A, Q207S, R211S, K238R, V245E, T286A, E291D, V292I, I293V, I309L, E312T, S322L, I326V, I329V, G335D, M357K, G359S, K366R, A371V, E399D, A400T, T403M, E432D, N447S, R448K, T470A, D471E, Q480H, H483C, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
VI-260 VI-260 None None   E6D, K11T, V35T, T39K, V106I, K122E, D123S, I135V, S162C, K173I, Q174K, D177E, I178M, Q207N, R211S, V245K, K281R, E291D, V292I, I293V, E312AT, I326V, I329V, G335GD, A355G, M357K, G359S, K366R, A371V, K395KR, A400T, T403M, Q428QR, E432D, N447S, V466VA, T470TI, D471E, Q480H, L491P, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
VI-262 VI-262 None None   E6D, K11T, V35T, T39K, K43Q, K122E, D123S, I142V, S162C, K173R, Q174K, D177E, V179I, I202V, Q207S, R211S, K238R, V245E, K249R, K281R, T286A, E291D, I293V, E312N, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, E449D, V466I, D471E, Q480H, H483Y, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554T  
VI-264 VI-264 None None   E6D, V35I, T107S, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, Q207S, R211S, K238R, V245E, A272P, K281R, T286A, E291D, V292I, I293V, E312T, I329V, G335D, R356RK, M357K, G359S, K366R, A371V, A376S, K385KR, K390R, K395R, T397TI, A400T, T403M, E432D, N447S, D471E, Q480H, H483Y, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
VI-265 VI-265 None None   E6D, V35T, T39K, K43E, K122E, D123S, S162C, K173I, Q174K, D177E, V179I, Q207S, R211S, K238R, V245E, A272P, K281R, A288T, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, R461K, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554L  
VI-271 VI-271 None None   E6D, K11T, V35T, T39K, K43E, T107S, K122E, D123S, S162C, K173I, Q174K, D177E, Q207T, R211S, V245E, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554Q  
VI-274 VI-274 None None   E6D, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, I202V, Q207N, R211S, K238R, V245E, A272P, V276VI, T286V, A288AT, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, V365VI, K366R, A371V, K390R, A400T, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, E514D, L517V, S519N, Q524E, K530R, A534S, Q547K, L551I, A554E G273R 
VI-275 VI-275 None None   V35T, T39K, K43E, K122E, D123S, S162C, F171Y, K173S, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, A272P, T286A, E291D, V292I, I293V, K311R, E312T, D324E, I329V, G335D, M357K, G359S, K366R, T369A, A371V, A376S, A400T, E432D, V435I, V458I, D471E, Q480H, L491S, I506L, K512R, L517V, S519N, Q524E, K527R, A534S, A554S  
VI-283 VI-283 None None   E6D, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207S, R211S, K238R, V245E, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T386I, K390R, I393L, A400T, T403M, V435I, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, K530R, A534S, A554S, I556V  
VI-285 VI-285 None None   E6D, K11T, V35T, T39N, V60I, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, T200A, Q207A, R211S, K238R, V245E, T286A, V292I, I293V, E312T, I329V, G335D, M357K, R358G, G359S, A360T, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554Q L205LI, K220KE 
VI-288 VI-288 None None   E6D, K11A, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, I202V, Q207N, R211S, K238R, V245E, A272P, K281R, E291D, I293V, L301F, E312T, V317VA, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S, I556V  
VI-292 VI-292 None None   E6D, V35T, T39K, K43Q, K122E, D123S, S162C, K173R, Q174K, D177E, I178M, Q207S, R211S, K238R, V245E, E291D, V292I, I293V, K311Q, E312N, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, E432D, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554T, K558R  
VI-296 VI-296 None None   E6D, K11T, V35T, T39Q, K122E, D123S, S162C, Q174R, D177E, I178M, T200I, Q207N, R211S, K238KR, V245E, T286A, E291D, V292I, I293V, P294PT, E297EA, E312NT, K323R, I326IV, I329V, G335D, M357K, G359S, K366R, A371V, V381VI, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
VI-300 VI-300 None None   E6D, K11T, V35T, T39KQ, K49KR, K82KR, K102Q, K122E, D123S, S162C, K173R, Q174K, D177E, I178M, T200TA, Q207X, R211S, K238R, V245Q, K281KR, T286A, E291D, V292I, I293V, E297EV, E312N, I326V, I329IV, G335D, M357K, G359S, K366R, A371V, K390R, K395KR, A400T, T403M, E432D, V435I, N447S, K454R, D471E, Q480H, H483Y, K512R, E514D, L517V, S519N, Q524E, A534S, A554S K43KEMV 
VI-309 VI-309 None None   E6D, K11T, V35T, T39N, S48T, R83RK, K122E, D123S, S162C, K173I, Q174K, D177E, T200A, Q207S, R211S, V245EK, A272P, T286A, E291D, V292I, I293V, E312A, I326V, I329V, G335D, M357K, G359S, K366KR, A371V, K390R, A400T, T403M, E432ED, N447S, D471E, Q480H, H483Y, L491S, A502AV, K512R, L517V, S519N, Q524E, A534S, A554S  
VI-314 VI-314 None None   E6D, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, Q207N, R211S, K238R, V245E, A272P, K281R, E291D, V292I, I293V, E297G, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K395R, A400T, T403TM, E432D, V435I, N447S, D460N, D471E, Q480H, H483Y, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S, K558R  
VI-316 VI-316 None None  K103N P4PS, E6D, K11T, V35T, T39K, K43KE, K101KQ, K122E, D123S, S162C, K173I, Q174K, D177E, I178IM, V179I, T200TK, I202V, Q207NS, R211S, V245Q, V276VI, T286A, E291D, V292I, I293V, E312T, I326V, I329IV, G335D, M357K, G359S, K366R, A371V, A400T, T403M, E432D, N447S, D471E, Q480H, H483HY, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, I556V  
VI-327 VI-327 None None   E6D, K11T, V21I, V35T, T39E, K64R, K122E, D123S, S162C, K173I, Q174K, D177E, I195IT, T200L, Q207K, R211S, K238R, V245E, T286A, E291D, V292I, I293V, R307K, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, V381I, K390R, A400T, T403M, E413D, E432D, N447S, D471E, Q480H, L491S, I505V, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
VI-329 VI-329 None None   E6D, K11T, V35T, T39X, D123S, S162C, K173M, Q174K, D177E, T200I, Q207S, R211S, V245E, K281R, T286A, E291D, V292I, I293V, E312T, I326V, G335D, M357K, G359S, T369A, A371V, I375V, A376S, A400T, T403M, E432D, V435A, N447S, D460NS, R461K, D471E, Q480H, L491S, K512R, E514D, L517I, S519N, Q524E, A534S, A554S  
VI-333 VI-333 None None   E6D, K11T, V35T, K122E, D123S, I142V, S162C, K173I, Q174K, D177E, Q207GS, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, V381VI, K390R, A400T, T403M, E432D, D460N, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, K527KR, A534S, A554S, K558R  
VI-338 VI-338 None None M41ML  E6D, K11T, K22R, V35T, T39K, W88S, K122E, D123S, A158T, S162C, K173I, Q174K, D177E, I178M, V179I, T200I, Q207N, R211S, K238R, V245E, I293V, E312T, I329V, G335D, M357K, G359S, K366R, A371V, A376S, K390R, K395R, A400T, E432D, V435A, N447S, D471E, Q480H, H483Q, L491S, K512R, E514D, S519N, Q524E, A534S, A554S  
VI-345 VI-345 None None   E6D, V35T, T39N, K122E, D123S, S162C, K173T, Q174K, D177DE, Q207S, L210M, R211RS, K238R, V245E, K281KR, T286TA, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, T470TS, D471E, L491S, E514D, L517V, S519N, Q524E, A534S, A554S  
VI-351 VI-351 None None   K11T, V35T, T39DN, D121A, K122E, I142V, S162C, K173I, Q174K, D177E, V179I, Q207A, R211S, K238R, V245E, E291ED, V292I, I293V, E312I, I329V, G335D, M357K, G359S, K366R, A371V, A376S, K390R, A400T, T403M, E432D, N447NS, D471E, Q480H, H483Q, L491S, K512R, L517I, S519N, Q524E, A534S, V548VI, A554K  
VI-359 VI-359 None None   E6D, K11T, V35T, T39K, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, Q207KN, R211NS, V245E, E248D, K281R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, V435I, N447S, D471E, K476Q, T477TA, Q480H, L491S, K512R, E514D, L517I, S519N, Q524E, A534S, A554S G436GR 
VI-366 VI-366 None None   P4S, E6D, K11T, V111I, K122E, D123S, S162Y, K173I, Q174K, D177E, V179I, I195V, Q207S, R211S, F214L, K238R, V245E, E248D, T286A, I293V, E312T, G335D, M357Q, G359S, K366R, A371V, K390R, K395R, A400T, T403R, E432D, N447S, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554N V442VAIT 
VI-375 VI-375 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207K, R211S, K238R, V245E, D250E, A272S, E291D, V292I, I293V, K311R, E312T, I326IV, I329V, G335D, M357K, G359H, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Y, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S T472A 
VI-377 VI-377 None None   E6D, K11T, V35T, T39N, K103KE, D121H, K122E, D123N, S162C, K173I, Q174K, T200A, Q207S, R211S, V245E, A272S, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, V435A, Q464K, K465R, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, E529D, A534S, A554S  
VI-378 VI-378 None None   E6D, V35T, T39K, K122E, D123S, S162Y, K173IM, Q174K, D177G, V179I, Q207S, R211S, K238R, V245E, K249R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471G, Q480H, H483Y, L491S, K512R, E514D, L517I, S519N, Q524E, A534S, A554S  
VI-392 VI-392 None None   E6D, K11T, V35T, K122E, D123S, S162C, K173I, Q174K, D177E, Q207S, R211S, K238R, V245E, E248D, K277R, T286A, I293V, E312T, G335D, M357Q, G359S, K366R, A371V, K395R, A400T, T403R, E432D, N447S, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554N  
VI-396 VI-396 None None   E6D, V35T, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, I202V, Q207A, R211S, K238R, V245E, K277R, T286A, E291D, I293V, E312A, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376S, K390R, A400T, T403M, E432D, N447S, D471E, K476KR, Q480H, L491S, I505V, K512R, L517V, S519N, Q524E, A534S, A554S  
VI-405 VI-405 None None   E6D, K11S, E28K, K32E, V35T, T39K, V60I, K102KR, K122E, D123N, S162C, K173I, Q174K, D177E, T200A, Q207S, R211S, K238R, V245E, A272P, K281KR, L283I, E291ED, V292I, I293V, E312T, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, V435I, N447S, D471E, Q480H, H483Q, L491S, K512R, E514D, Q524E, A534S, A554S  
VI-407 VI-407 None None   E6D, K11T, V35T, K122E, D123S, S162C, K173I, Q174K, D177E, Q207A, R211S, K238R, V245E, K281R, T286A, E291D, V292I, I293V, E312T, I329V, G335D, M357K, G359S, K366R, A371V, I382V, K390R, A400T, T403M, E432D, V435I, N447S, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, K527N, E529D, A534S, A554S  
VI-408 VI-408 None None   E6D, K11T, V35T, T39E, K122E, D123N, S162C, K173I, Q174K, D177E, Q207S, R211S, K238R, V245E, A272P, I293V, E312NT, D324DE, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, H483Y, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554AS  
VI-417 VI-417 None None   E6D, K11A, T27S, V35T, D121H, K122E, D123S, S162C, K173I, Q174K, D177E, T200A, Q207S, R211S, K238R, V245E, A272AP, T286A, E291D, V292I, I293V, E312N, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, A400T, T403M, E432D, N447S, L452I, D471E, Q480H, H483Q, L491A, K512R, E514D, L517V, S519N, Q524E, A534S  
VI-419 VI-419 None None   E6ED, V8I, K11T, V35T, T39N, V60I, V106I, K122E, D123N, S162C, K173IT, Q174K, D177E, I178M, V179I, T200A, E203D, Q207A, R211S, K238R, V245E, A272P, T286A, I293V, K311R, E312T, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403TM, E432D, N447S, R463K, D471E, Q480H, H483Y, L491S, K512R, L517I, S519N, Q524E, E529D, A534S, A554K, K558R