<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Courtney (2015)
Title Monitoring HIV-1 group M subtypes in Yaounde, Cameroon reveals broad genetic diversity and a novel CRF02_AG/F2 infection.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 109
NumPts 108
Subtype CRF02_AG, A, F, CRF18_cpx, D, A + G, G, CRF11_cpx, A + J, CRF09_cpx, H

 

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Page 1   listing Isolate 1 to Isolate 100 from Total 109 Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
MDC001 MDC001-1 None None   V60I, V118M, K122P, D123S, I135V, F171Y, K173A, Q174K, D177E, Q207A, R211K, F214L, V245Q, K277R, T286A, E291D, V292I, I293V, E297A, I326V, G335D, R356K, M357R, G359S, T369V, A371V, I375V, K390R, T403I, E404D, K431T, V435I, D471E, T477A, L491S, L517I, S519N, Q520H G99E, D488N 
  MDC001-2 None None   V245Q, K277R, T286A, E291D, V292I, I293V, P294S, E297A, I326V, G335D, R356K, M357R, G359S, T369V, A371V, I375V, K390R, T403I, E404D, K431T, V435I, D471E, T477A, L491S, L517I, S519N, Q520H, Q524E D488N 
MDC002 MDC002-1 None None  V179E T39A, V60I, K64R, D123S, I135L, S162A, K173A, Q174K, D177E, T200A, E204D, Q207G, R211K, V245Q, T286A, E291D, V292I, I293V, P294T, E298K  
  MDC002-2 None None  V179E T39A, V60I, K64R, K104R, D123S, I135L, S162A, K173A, Q174K, D177E, T200A, E204D, Q207E, R211K, V245Q, T286A, E291D, I293V, P294T  
MDC003 MDC003-1 None None   K43N, K49R, V60I, D123E, S162C, D177E, I178L, E204K, Q207E, V245E, D250E, A272P, T286A, I293V, E297K, I326V, I329Y, Q330X, K331X  
MDC004 MDC004-1 None None   K122P, I135V, S162A, Q174D, D177E, T200A, Q207E, V245C, K277R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, R356K, M357K, G359S, T369A, A371V, I375A, A376T, K390R, K395R, T403M, E432D, V435I, D471E, Q480H, H483Q, L491S, K512R, S519N  
MDC006 MDC006-1 None None   V60I, K122E, I135L, S162A, T165TP, K173A, Q174K, D177E, I178M, V179I, T200A, Q207E, R211K, V245Q, E248N, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357R, G359S, A371V, I375V, A376S, T386I, K390R, E432D, D471E, Q480H, L491S, K512R, S519N, Q520L  
  MDC006-2 None None   V60I, K122E, I135L, S162A, K173A, Q174K, D177E, I178M, V179I, T200A, Q207E, V245Q, E248N, T286A, E291D, V292I, I293V, P294T, S322T, D324E, I326V, G335D, R356K, M357R, G359S, A371V, I375V, A376S, T386I, K390R, E432D, D471E, Q480H, L491S, K512R, S519N, Q520L  
  MDC006-3 None None   V60I, K122E, I135L, S162A, K173A, Q174K, D177E, I178M, V179I, T200A, Q207E, R211K, V245Q, E248N, T286A, E291D, I293V, P294T, S322T, I326V, G335D, R356K, M357R, G359S, A371V, I375V, A376S, T386I, K390R, E432D, D471E, Q480H, L491S, K512R, S519N, Q520L  
MDC007 MDC007-1 None None M184V  T39M, K122E, D123S, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, A272G, K277R, T286A, E291D, I293V, P294T  
MDC008 MDC008-1 None None   I132V, I135V, S162A, K173R, Q174K, D177E, T200A, Q207E, V245K, L283I, T286A, E291D, V292I, I293V, P294T, L295M, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375A, V381I, K388R, K390R, T403M, D471E, T477S, Q480H, H483L, L484I, Q487K, L491S, I495V, S519N  
  MDC008-2 None None   D123N, I132V, I135V, S162A, K173G, Q174K, D177E, T200A, Q207E, V245K, L283I, T286A, E291D, V292I, I293V, P294T, L295M, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375A, V381I, K388R, K390R, T403M, D471E, T477S, Q480H, H483L, L484I, Q487K, L491S, I495V, S519N  
MDC011 MDC011-1 None None   V245Q, D250E, K281R, T286A, E291D, V292T, I293V, P294T, S322T, D324E, I326V, Q334H, G335D, R356K, M357K, G359S, T369V, E370Q, A371V, I375V, T377V, K390R, A400T, T403L, V435L, D471E, Q480H, L491S, K512R, L517I, S519N, Q520T, Q524K, I526M  
MDC012 MDC012-1 None None   V245Q, E248N, V261I, K275Q, T286A, E291D, V292I, I293V, P294T, S322A, I326V, Q334P, G335D, R356K, M357R, G359S, T369V, A371V, I375V, V381I, K390R, T403Q, Y405H, V435I, F440Y, R461K, D471E, Q480H, I482V, H483Y, L491S, S519N, Q524K, I526M  
  MDC012-2 None None   K122E, D123E, I142V, S162A, F171Y, K173T, Q174K, D177E, T200A, Q207E, F214L, V245Q, E248N, V261I, V276I, T286A, E291D, V292I, I293V, P294T, S322A, I326V, Q334P, G335D, R356K, M357R, R358K, G359S, T369V, A371V, I375V, V381I, K390R, T403Q, Y405H, V435I, F440Y, R461K, D471E, Q480H, I482V, H483Y, L491S, S519N  
  MDC012-3 None None   K122E, D123E, I142V, S162A, F171Y, K173T, Q174K, D177E, T200A, Q207E, F214L, V245Q, E248N, V261I, V276I, T286A, E291D, V292I, I293V, P294T, S322A, I326V, Q334P, G335D, R356K, M357R, G359S, T369V, A371V, I375V, V381I, K390R, T403Q, Y405H, V435I, F440Y, R461K, D471E, Q480H, I482V, H483Y, L491S, A502V, S519N  
MDC018 MDC018-1 None None   T39L, S68G, D121Y, K122E, I135V, S162A, K173T, Q174K, D177E, I178L, T200A, Q207N, R211K, P243T, V245Q  
  MDC018-2 None None   T39L, S68G, D121Y, K122E, I135V, S162A, K173T, Q174K, D177E, I178L, T200A, Q207N, R211K, P243T, V245Q, T286A, E291D, V292I, I293V, P294T, S322T, I326V, Q334P  
MDC019 MDC019-1 None None   T39N, K122E, D123N, S162C, E169D, K173A, Q174K, D177E, G196E, Q207A, R211S, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294T, E297R, A304E, G335D  
MDC023 MDC023-1 None None   T39N, V60I, D121Y, K122E, I135V, S162A, K173T, Q174K, D177K, I178M, T200A, Q207D, R211K, Y232X, D237X, V245X, E248X, D250E, I257X, A267X  
MDC026 MDC026-1 None None   T39L, K122E, D123E, S162A, Q174E, D177E, T200A, Q207A, R211K, V245Q, E248D, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357R, R358G, G359S, H361P, T362P, E370A, A371V, I375V, T377V, K388X, K390R, E399D, T403M  
  MDC026-2 None None   I142V, S162A, K173A, Q174K, D177E, I178M, V179G, T200E, E203Q, Q207N, R211N, V245K, T286A, V292I, I293V, S322A, A327V, Q334D, G335D, R356K, M357R, R358K, G359S, A371V, I375V, A376T, K390R, E432D, V435I, Q480H, L491S, K512R, E516Q, S519N  
MDC029 MDC029-1 None None   V60I, D121Y, K122E, I135T, E138A, T139A, S162C, R172K, Q174E, D177E, I178L, T200A, E204Q, Q207D, R211K, F214L, P243T, V245T, D250E, A272P, K277R, T286A, E297K, K311R, I329L, G333E, Q334G, Y339W, M357R, V365I, K374R, K390R, V435I, A437V, E449D, V467I, L469F, H483N, L491P, E516D, L517V, S519N Q182S 
MDC030 MDC030-1 None None   T39L, K49R, V106I, D121Y, K122E, A158S, S162C, D177E, I178L, V179I, T200A, Q207A, R211K, I244V, V245K, D250E D186E 
MDC037 MDC037-1 None None   T39A, E40D, I142V, S162A, K173A, Q174K, D177E, I178M, T200E, E203Q, Q207N, R211N, V245K, T286A, V292I, I293V, S322A, A327V, Q334D, G335D, R356K, M357R, R358K, G359S K350T, Y354I 
MDC040 MDC040-1 None None   T39S, K122E, D123S, I135V, S162A, K173T, Q174E, D177E, I178M, T200A, Q207E, V245K, T286A, E291D, V292I, I293V, P294T, L295M, L310P, K311R, V314G, V317A, P321S, I326V, G335D, Y342F, R356K G316A 
  MDC040-2 None None   K122E, D123S, A158S, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, Q278H, K281R, T286A, E291D, V292I, I293V, P294T, S322A, G335D, P345T, R356K, M357K, G359S, K366R, T369A, A371V, I375V, A376T, K390R, K395R, A400T, T403M, E432D, T470P, D471E, Q480H, H483Y, L491S, K512R, L517I, S519N  
MDC044 MDC044-1 None None   T39D, D123E, I135V, E169D, K173A, Q174K, N175Y, G196E, T200A, E203Q, Q207D, R211K, V245Q, D250E, V276I, T286A, E291D, I293V, G333E, Q334K  
  MDC044-2 None None   K122E, D123S, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, V245K, T286A, E291D, V292I, I293V, P294T, L295M, K311R, P321S, S322A, I326V, G335D, R356K, M357K, R358K, G359S, A371V, I375V, T377I, A400T, T403Q, R448K, R461K, S468T, D471E, Q480H, H483Y, L491S, K512R, S515A, L517V, S519N  
  MDC044-3 None None   K122E, D123S, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, V245K, T286A, E291D, V292I, I293V, P294T, L295M, K311R, P321S, S322A, I326V, G335D, R356K, M357K, R358K, G359S, A371V, I375V, T377I, A400T, T403Q, R448K, R461K, S468T, D471E, Q480H, H483Y, L491S, K512R, S515A, L517V, S519N  
MDC045 MDC045-2 None None   T39N, V60I, D121Y, K122E, I135V, S162A, K173T, Q174K, D177K, I178M, T200A, Q207D, R211K, V245Q, D250E, A272P V261L 
MDC047 MDC047-1 None None   I135V, S162A, Q174A, D177E, I178M, T200A, Q207E, R211K, P243S, V245Q, D250E, S251N, T286A, V292I, I293V, P294T, L295M, S322T, I326V, Q334P, G335D, R356K, M357K, G359S, K366R, A371V, I375V, T377I, T403M, I434L, V435M, A437V, R448K, D471E, Q480H, H483Y, L491S, K512R  
  MDC047-2 None None   T39M, I135V, S162A, Q174A, D177E, I178V, T200A, Q207E, R211K, P243S, V245Q, D250E, T286A, V292I, I293V, S322T, I326V, Q334P, G335D, Q336X, N348X, R356K Q85K, G352R 
MDC057 MDC057-3 None None   V60I, K122E, I135T, S162A, K173T, Q174D, D177E A129E, R172RIKT 
MDC059 MDC059-1 None None   K43N, D123E, I135V, S162A, K173A, Q174K, D177E, T200E, E203Q, Q207D, V245K, A272P, T286A, I293V, P294T, S322A, I326V, Q330P, G335D  
MDC060 MDC060-2 None None   T39K, D121H, K122E, I135V, I142V, E169D, K173A, D177E, G196E, E204Q, Q207D, R211K, V245M, E248D, S251C, A272P, K275Q, K277R, T286A, I293V, E312N, I326V, Q334L, G335D, I341V, M357K, G359S  
MDC068 MDC068-3 None None   T39K, K43E, K122E, D123S, S162A, K173T, Q174N, D177E, T200AEGV, E204Q, Q207E, R211K, F214L, V245H, K277R  
MDC075 MDC075-1 None None   V60I, K122E, D123N, I135T, S162C, R172K, D177E, I178L, T200A, E204K, Q207E, F214L, V245T, E248D, D250E, A272P, K277R, T286A, A288S, I293V, E297K, I329L, Y339W, M357K, A376S, K390R, T403M, V435A, S468P, L469F, H483N, L491S, L503I, K512Q, E516D  
  MDC075-2 None None   V60I, K122E, D123N, I135T, S162C, R172K, D177E, I178L, T200A, E204K, Q207E, F214L, V245T, E248D, D250E, A272P, T286A, A288S, I293V, E297K, I329L, Y339W, M357K, A376S, K390R, T403M, V435A, S468P, L469F, H483N, L491S, L503I, K512Q, E516D  
MDC079 MDC079-1 None None   K122E, D123N, I135V, S162A, F171Y, K173T, Q174R, D177E, I178M, T200A, Q207E, R211K, F214L, P243H, V245Q, K275R, T286A, K287R, E291D, V292I, I293V, P294A, S322T, I326V, R356K, M357K, G359S, A371V, I375V, V381I, K390R, A400T, T403M, R461K, D471E, Q480H, L491S, K512Q, S519N R78K 
MDC080 MDC080-1 None None   V60I, K122E, D123S, S162C, E169D, K173R, Q174K, D177E, G196E, T200A, Q207E, R211K, V245Q, D250E, S251D, A272P, T286A, V292I, I293V, P294T, E297A, E312A, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359A, A371V, A376S, Q394K, A400T, E413D, Q428R, K431T, V435A, F440Y, R461K, R463K, V467I, S468T, Q480H, H483Q, L491S, V496I, K512R, S519N  
MDC081 MDC081-1 None None   T39M, K49R, K101R, K102R, K104R, A158S, S162A, Q174K, D177E, V179I, E194D, T200A, I202V, Q207E, R211K, E248D, T286A, E291D, V292I, I293V, P294T, S322A, G335D, R356K, M357R, G359S, H361P, T362P  
MDC086 MDC086-1 None None   T39L, D121H, K122E, D123S, S162A, K173A, Q174K, T200A, Q207E, R211K, V245Q, T286A, E291D, V292I, I293V, E305ED, K311R, E312ED, P313X, S322A G285G*R, E302D 
MDC093 MDC093-1 None None   V90I, K122R, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207N, R211K, V245Q, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359A, I375V, K390R, T403M, E432D, V435L, A446S, R461K, D471E, Q480Y, L491S, S519N  
  MDC093-2 None None   T39L, V90I, K122R, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207N, R211K, V245Q, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, Y339F, F346L, R356K, M357K, R358E Y354I, A355C 
MDC098 MDC098-1 None None   K122E, D123S, S162A, K173T, Q174N, D177E, Q197E, T200A, E204Q, Q207E, R211K, F214L, V245Q, K277R, T286A, E291D, I293V, S322T, I326V, Q334H, G335D, R356K, M357R, G359S, T369V, A371V, I375V, K390R, T403L, K431R, E432D, V435A, L452Q, D471E, Q480H, H483Y, L491P, K512R, L517I, S519N, Q520L  
  MDC098-2 None None   T39K, K43E, K122E, D123S, S162A, K173T, Q174N, D177E, T200A, E204Q, Q207E, R211K, F214L, V245H, K277R, T286A, E291D, I293V, L310X, V314G, H315P, S322X, I326V, I329Y, Q330R, K331N, G333X, Q334X, Q336P, Y339F, I341X, P345X E302K 
  MDC098-3 None None   K122E, D123S, S162A, K173L, Q174K, D177E, T200A, Q207E, V245Q, E248N, V276I, T286A, E291D, V292I, I293V, P294T L279LMV 
MDC100 MDC100-1 None None   K122E, D123N, S162A, K173T, Q174N, D177E, T200E, E204Q, Q207G, R211K, F214L, V245Q, K277R, T286A, E291D, I293V, S322T, I326V, G335D, R356K, M357R, G359S, T362N, T369V, A371V, I375V, K390R, A400T, T403I, K431R, E432D, V435A, L452Q, D471E, Q480H, L491P, K512R, L517I, S519N  
  MDC100-2 None None   T39K, K43E, K122E, D123N, S162A, K173T, Q174N, D177E, T200E, E204Q, Q207G, R211K, F214L, V245Q, T286A, E291D, I293V, S322T, I326V, G335D, R356K, M357R, G359S  
  MDC100-3 None None   K122E, D123N, S162A, K173T, Q174N, D177E, T200E, E204Q, Q207G, R211K, F214L, V245Q, T286A, E291D, I293V, S322T, I326V, G335D, R356K, M357R, G359S, T362N, T369V, A371V, I375V, K390R, A400T, T403L, K431R, E432D, V435A, L452Q, D471E, Q480H, L491P, K512R, L517I, S519N  
MDC102 MDC102-1 None None   P243T, V245Q, E248D, T286A, E291D, I293V, E297K, L310I, S322A, I326V, G335D, R356K, M357K, G359S, A371V, I375V, T377M, K390R, K395R, A400T, T403M, E432D, N447D, T450N, D471E, Q480H, H483Y, L491S, K512R, E514D, S519N, Q520L, Q524K, I526M E449K 
  MDC102-2 None None   T39A, K43S, K64R, R125K, I135V, S162A, E169Q, K173T, Q174K, D177K, G196E, T200A, Q207E, D218N, P243T, V245Q, E248N R78K, E79K, R143K, G262GAEV, Q269QH 
MDC116 MDC116-1 None None   E40D, V60I, S68G, V118C, K122E, I135V, S162A, K173T, Q174K, D177E, T200A, E203K, Q207E, R211K, V245K, D250E, S251N, A272P  
MDC125 MDC125-1 None None   K122E, I135V, I142T, S162A, E169K, K173T, Q174E, D177E, T200V, Q207E, V245Q, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, K366R, K390R, E396D, V435L, A446S, L452I, R461K, D471E, K476Q, H483Y, L491S, K512Q, E514D, L517I, S519N  
MDC128 MDC128-1 None None   T39K, V60I, K122E, K173T, Q174K, D177E, I178M, E194D, T200A, Q207E, R211K, F214L, V245Q, E248D, D250E, A272P, Q278H, K281R, T286A, A288T, E291D, V292I, I293V, E297A, L301M, D324E, I329V  
MDC131 MDC131-2 None None   K122E, D123S, S162A, K173L, Q174K, D177E, T200A, Q207E, V245Q, E248N, T286A, E291D, V292I, I293V, P294T, S322A, G335D, R356K, M357K, G359S, K366R, T369A, I375V, K390R, E399D, T403Q, D471E, Q480H, H483Y, L491S, A502G, K512R, S519N  
  MDC131-3 None None   D123E, S162A, K173A, Q174K, D177E, Q207E, R211K, P243A, V245Q, E248D, D250S, A272P, K275R, Q278QH, L279X, T286A K201K*EQ 
MDC135 MDC135-1 None None   K122E, D123G, S162D, K173T, Q174E, D177E, T200A, Q207E, R211K, V245Q, K281R, T286A, E291D, I293V, P294I, S322A, I326V, G335D, R356K, M357K, G359S, A371V, A376V, K390R, T403M, R463K, D471E, Q480H, L491S, S519N E344K 
MDC142 MDC142-2 None None   T39N, K122E, D123S, I135V, E169D, K173A, Q174K, D177E, G196E, E203D, Q207A, R211N, V245Q, E248D, A272P, V276I, T286A, E291D, I293V I270INST 
MDC143 MDC143-1 None None   K122E, E138A, S162A, K173T, Q174K, D177E, I178V, V179I, T200A, Q207D, P243T, V245Q, D250E, T286A, E291D, V292I, I293V, S322A P294M 
MDC153 MDC153-1 None None   V60I, I135V, S162A, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, F214L, K238R, V245Q, T286A, E291D, V292I, I293V, P294T, K311R, S322T, K323R, D324E, I326V, G335D, R356K, M357R, G359S, A371V, I375V, S379G, V381I, K390R, T403M, R461K, L469I, D471E, Q480H, L491S, K512R, L517I, S519N  
  MDC153-2 None None   S162A, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, F214L, V245Q, T286A, E291D, V292I, I293V, P294T, K311R, S322T, I326V, G335D, R356K, M357R, G359S, A371V, I375V, S379G, V381I, K390R, T403M, L469I, D471E, Q480H, L491S, K512R, L517I, S519N  
MDC162 MDC162-1 None None   T39L, K101R, K104R, D123E, S162C, K173T, Q174K, D177E, T200E, I202V, Q207K, P243T, V245Q, E248D, A272P, K275R, Q278H, T286A, E291D, I293V, E297T, K323R, D324E, G335D, F346H  
  MDC162-2 None None   T39L, K101R, K104R, D123E, S162C, K173T, Q174K, D177E, T200E, I202V, Q207K, P243T, V245Q, E248D, A272P, K275R, Q278H, T286A, E291D, I293V, E297T  
MDC164 MDC164-1 None None   P243A, V245Q, E248D, D250N, A272P, K275R, Q278H, T286A, E291D, I293V, E297A, Q334H, G335D, F346H, R356K, M357R, G359T, I375V, T386I, K390R, E432D, I434L, A437V, D471E, H483L, G490E, L491S, Q509H, S519N, Q524H  
  MDC164-2 None None   D123E, I135V, K173A, Q174K, D177E, I178V, Q207E, R211K, P243A, V245Q, E248D, D250N, A272P, K275R, Q278H, T286A, E291D, I293V, E297A K323KN 
MDC166 MDC166-1 None None  K103N T39L, D123E, I135V, I142M, S162A, K166N, K173T, Q174A, D177E L187S 
MDC167 MDC167-1 None None   K122E, D123N, K173T, D177E, T200E, I202V, Q207EK, R211K, P243T, V245Q, E248D, D250E, S251C, Y271F, A272P, E291D, I293V, E297A, S322T, I329V, Q334L, G335D, R356K, M357R, G359S, K366R, A371V, I375V, T377Q, S379C, K390R, K395R, A400T, E404D, V435I, L452I, R461K, S468T, D471E, Q480E, L491P, I495V, V496I, L517I  
MDC172 MDC172-1 None None   V245K, D250E, S251N, K281R, T286A, E291D, V292I, I293V, P294T, L295M, E297K, R307K, S322A, D324E, G335D, M357K, G359S, K366R, T369A, A371V, I375V, A376T, K390R, K395R, A400T, T403M, E404D, V435I, K451R, S468P, D471E, Q480H, L491S, K512R, S515T, L517I, S519N, Q520L, Q524K, I526M  
  MDC172-2 None None   T39N, E40D, K43R, V60I, K102Q, K104R, D123N, I135V, K173A, D177E, Q207E, R211K, V245K, D250E, S251N, E291D, V292I, I293V, P294T, L295M, E297K, R307K, S322A, D324E, G335D, M357K, G359S, K366R, T369A, A371V  
  MDC172-3 None None   V60I, K102Q, K104R, D123N, I135V, K173A, D177E, T200A, Q207E, R211K, V245K, D250E, S251N, K281R, E291D, V292I, I293V, P294T, L295M, E297K, R307K, S322A, D324E, G335D, M357K, G359S, K366R, T369A, A371V, I375V, A376T, K390R, K395R, A400T, T403M, E404D, V435I, K451R, S468P, D471E, Q480H, L491S, K512R, S515T, L517I, S519N, Q520L  
MDC179 MDC179-2 None None   D123E, S162A, K173T, Q174A, D177E, Q207E, R211K, P243A, V245Q, E248D, D250S, A272P, K275R, L283I, T286A, E291D, I293V, E297A, L303M, V317A, I329V, Q334Y, G335D, F346H, R356K, M357R, R358K, G359S, A371V, A376S, T386I, K390R  
MDC182 MDC182-1 None None   V60I, K122P, I135V, K173T, Q174R, D177E, Q207E, P243S, V245T, E248D, A272Q, K277R, T286A, E291D, I293V, E312D, S322A, Q334H, G335D, R356K, M357R, G359S, T369V, A371V, I375V, T386I, K390R, A400T, E404D, P421H, K431T, L452K, V458I, D471N, L491S, E492K, A502S, L517I, S519N  
MDC187 MDC187-1 None None   T39S, K49R, I50V, V60I, I135V, I142V, S162A, K173I, Q174K, D177E, I178M, T200A, Q207G, R211K, V245Q, E248D, A272P, L283I, T286A, E291D, V292I, I293V  
  MDC187-2 None None   V60I, I135V, I142V, S162A, K173I, Q174K, D177E, I178M, T200A, Q207G, R211K, V245Q, E248D, A272P, L283I, T286A, E291D, V292I, I293V, S322T, I326V, G335D, M357R, R358K, G359S, K366R, T369A, A371V, K374R, I375V, K390R, T403M, E432D, V435A, R461K, D471E, Q480Y, H483F, L491S, E514D, L517S, S519N  
MDC189 MDC189-1 None None   V245Q, E248N, A272P, V276T, T286A, E291D, V292I, I293V, S322E, D324E, I326V, R356K, M357I, R358K, G359S, T369V, A371V, I375V, A376T, T377M, K390R, T403L, E432D, V435I, D471E, Q480H, H483Y, L491S, K512R, S515A, S519N, Q524K, I526M  
  MDC189-2 None None   K122E, D123S, S162A, K173T, Q174N, D177E, T200A, Q207E, V245Q, E248D, A272P, V276T, T286A, E291D, V292I, I293V, S322E, D324E, I326V, R356K, M357I, R358K, G359S, T369V, A371V, I375V, A376T, T377M, K390R, T403L, E432D, V435M, D471E, Q480H, H483Y, L491S, K512R, S519N  
MDC192 MDC192-1 None None   V245Q, T286A, E291D, V292I, I293V, P294T, K311R, S322T, I326V, Q334P, G335D, R356K, M357K, G359S, K366R, T369V, I375V, K390R, T403M, E432D, R461K, V467I, S468T, D471E, Q480H, L491S, K512R, L517V, S519N, Q524K  
  MDC192-2 None None   S162A, F171Y, K173T, Q174K, D177E, T200A, Q207K, R211E D76Y, Y232Y* 
MDC195 MDC195-2 None None   T39N, V60I, K104R, D121H, K122E, D123G, I135T, I142V, D177E, G196E, T200A, E203Q, Q207A, R211T, K238E, V245Q D218DHNY, E248Y 
MDC209 MDC209-1 None None   T39K, I135V, S162A, K173T, Q174N, D177E, T200A, Q207E, R211K, V245K, E248D, T286A, E291D, V292I, I293V, P294V  
MDC216 MDC216-1 None None   K122E, E169D, K173A, Q174K, D177E, V179I, G196E, Q207S, R211S, V245Q, E248D, D250E, S251C, A272S, T286A, I293V, A304G L303F, E305R, N306Q 
MDC220 MDC220-2 None None   T39A, K104R, D121Y, K122E, I135T, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, P243S, V245Q, D250E, K281R, L283I, T286A, I293V, E300D, E312N  
MDC221 MDC221-2 None None   T39A, D123E, I135V, I142V, S162A, K173T, Q174K, D177E, T200A, Q207K, R211A, V245Q, E248D, K275Q, T286A, E291D, V292I, I293V, S322T  
MDC222 MDC222-2 None None   E40D, K49R, K104R, V118I, K122E, D123S, S162T, K166R, K173A, Q174K, D177E, T200A, Q207E, V245Q, K277R, T286A, K287R, E291D, V292I, P294T R284RKMT 
MDC223 MDC223-1 None None   I135V, A158S, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, P225S, V245Q, K281R, T286A, E291D, I293V, P294T, E297K, S322A, G335D, R356K, M357R, G359S, A371V, I375A, T377L, K390R, K395R, T403M, E432D, D471E, H483Y, L491S, A502S, K512R, L517V, S519N  
  MDC223-3 None None   I135V, A158S, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, K281R, T286A, E291D, I293V, P294T, E297K, S322A, G335D, R356K, M357R, G359S, A371V, I375A, T377L, K390R, K395R, T403M, E432D, D471E, H483Y, L491S, A502S, K512R, L517V, S519N  
MDC227 MDC227-1 None None   V60I, K122E, D123N, I135T, Q145C, S162A, K173T, Q174E, D177E, V189I, T200A, Q207E, R211K, F214L, V245K, S251N, T286V, A288S, E291D, V292I, I293V  
MDC231 MDC231-1 None None   T39L, I135V, I142V, S162A, K173T, D177E, T200A, Q207E, P243Q, V245Q, Y271F, K281R, T286A, K287R, E291ED, I293V, P294T  
  MDC231-2 None None   T39L, K122Q, I135V, I142V, S162A, K173T, Q174R, D177E, T200A  
MDC232 MDC232-1 None None   T39K, S105A, S162A, K173T, Q174S, D177E, T200A, Q207E, F214L, V245Q, E248D, A272P, T286A, A288T, E291D, V292I, I293V A267Q, S268V, Q269R, I270F, Y271YDHN 
MDC235 MDC235-2 None None   T39K, K43E, K49R, K122E, D123S, I135T, T165I, E169D, K173A, Q174K, D177E, V179I, G196E, T200A, I202V, Q207A, R211S, V245K, D250E, T286A, E291D, I293V, Q330QLPR, G335D, M357K, G359S, A360T, K366R, I375V  
MDC237 MDC237-1 None None   T39N, K104R, D123N, S162C, K173T, D177E, T200E, I202V, Q207E, R211K, V245Q, D250E, S251D, A272P, L283I, E291D, V292I, I293V, I329V, Q334L, G335D  
  MDC237-2 None None   T39N, K104R, K122A, D123N, S162C, K173T, D177E, T200E, I202V, Q207E, R211K, V245Q, D250E, S251D, A272P, L283I, E291D, V292I, I293V, I329V, Q334L, G335D  
MDC240 MDC240-1 None None   T39A, K49R, V60I, I135T, S162A, F171Y, K173T, Q174E, D177E, T200A, Q207E, V245Q, T286A, E291D, V292I, I293V, P294T, S322A, I326V, G335D, R356K, M357R, G359T, T377V  
MDC243 MDC243-1 None None   K49R, I135T, F171Y, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, V245Q, E248N, D250E, A272P, K281R, T286A, E291D, V292I, I293V Q269QH, I270INST 
  MDC243-2 None None   K49R, I135T, T165I, F171Y, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, V245Q, E248N, D250E, A272P, K281R, T286A, E291D, V292I, I293V  
MDC244 MDC244-1 None None   V60I, V90I, D123E, I135V, S162A, K173T, Q174G, D177E, T200A, Q207E, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, V317I, P321S, S322T, I326V, G335D, R356K, M357X, G359S  
MDC265 MDC265-1 None None   V90I, S162A, K173T, Q174R, D177E, I178M, T200A, Q207E, R211K, P243T, V245Q, T286A, E291D, V292I, I293V, S322A, I326V, G335D, R356K, M357K, G359T, A360T, K366R, T369A, I375V, T377Q, S379C, K390R, A400T, D471E, Q480H, H483Q, L491S, K512R, S519N