<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Billings (2016)
Title The number and complexity of pure and recombinant HIV-1 strains observed within incident infections during the HIV and malaria cohort study conducted in Kericho, Kenya, from 2003 to 2006.
Citation PLoS ONE
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 58
NumPts 58
Subtype A, D, C, G

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
KE149896V6 KE149896V6 None None   V35T, V60I, K64R, K122E, S162A, D177E, Q207A, R211S, T286A, E291D, I293V, P294T, E312D, I329V, G335D, M357R, G359S, T369V, A371V, I375V, A376S, T377M, K388R, K390R, A400T, T403V, E404D, E432D, V458I, D471E, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527G, E529D, A534S, A554S  
KE161801V6 KE161801V6 None None   T27A, V60I, D121H, K122E, D123A, I135T, K173S, Q174K, D177E, T200A, Q207A, R211S, V245M, D250E, K275Q, V276I, Q278H, T286A, E291D, V292I, I293V, P294T, E312N, S322T, G335D, M357K, G359S, K366R, T369A, A371V, I375V, A376V, T377M, A400T, T403M, E404D, E432D, V435A, E449G, D471E, Q480H, H483L, L491S, E514D, S519N, Q524K, K527G, E529D, A534S, Q547K, A554S  
KE169579V3 KE169579V3 None None   K11T, K20R, V35T, T39K, E40D, D123N, K173S, Q174R, D177E, V179I, Q197L, T200Q, I202V, E203D, Q207D, R211K, V245Q, E248D, T286A, E291D, I293V, P294T, G335D, M357K, G359S, A360T, I375V, A376V, T377M, A400T, T403M, E404D, E432D, D471E, Q480H, L491S, S519N, Q524K, K527E, E529D, K530R, A534S, A554S N54NS 
KE176519V4 KE176519V4 None None   K20R, V35I, V60I, D121Y, K122E, I135T, K173T, Q174K, D177E, I178V, V179I, T200A, Q207A, R211K, F214L, V245K, D250E, K281R, T286A, E291D, I293V, P294T, K311R, E312N, G335D, M357K, G359S, T369A, A371V, I375V, A376V, T377L, A400T, T403M, E404D, E432D, V467I, D471E, Q480H, L491S, K512R, S519N, Q524K, K527G, E529D, A534S, A554S  
KE185405V4 KE185405V4 None None   V35T, V60I, D121Y, K122E, I135T, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, V245E, D250E, S251N, Q278R, T286A, E291D, V292I, I293V, E312D, E344D, M357K, G359S, K366R, A371V, I375V, A376V, T377I, A400T, T403M, E404D, E413D, E432D, V435A, R463K, D471E, K476R, Q480H, H483L, L491S, K512R, S515A, S519N, Q524E, K527G, E529D, A534S, A554S  
KE196199V6 KE196199V6 None None   E6N, K20R, V35T, T39K, V60I, V118I, K122E, D123S, I135T, K173A, Q174K, D177E, I178L, V179I, T200A, I202V, Q207G, R211S, F214L, V245E, D250E, E291D, V292I, I293V, P294T, E312D, V317A, G335D, M357K, G359S, A371V, I375V, A376V, T377M, K390R, A400T, T403M, E404D, E432D, V435A, D471E, Q480H, L491S, K512R, S519N, Q524K, K527G, E529D, Y532H, A534S, A554R, G555D, K558R  
KE215154V4 KE215154V4 None None   V35T, V60I, K122E, D177E, I178L, Q207E, R211K, V245K, E248D, D250E, A272P, K277G, L282C, L283I, T286A, V292I, I293V, Q334P, G335D, F346Y, K350R, R356K, M357R, I375M, T377Q, S379C, T386A, K390R, A400T, K431Q, N447S, L452M, T470A, H483N, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554S G155R 
KE263806V2 KE263806V2 None None   V35T, V60I, K64R, K122E, D123S, I135T, E138A, I142V, K173L, Q174K, V179I, Q207A, R211S, V245E, D250E, A272G, V276I, K277R, K281R, T286A, E291D, V292I, I293V, P294T, E312D, G335D, M357K, G359T, K366R, T369A, A371V, I375V, A376V, T377M, K390R, K395R, E396D, A400T, T403M, E404D, E432D, S468P, D471E, Q480H, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554S, V559I  
KE275457V6 KE275457V6 None None   E6N, V35T, E40D, K49R, I50V, E53D, V60I, K122E, D123S, K166Q, R172K, Q174E, D177E, I178M, D192N, T200A, E203K, E204K, Q207E, E224K, V245Q, E248D, D250E, A272P, K275Q, T286A, E291D, V292I, E297T, P321S, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, V365I, A371L, A376C, T386I, K390R, Q394R, A400V, E404D, E413D, Q428R, K431T, V435P, F440Y, R463K, V466I, S468T, L469I, D471E, H483Q, L491S, Q509H, K512R, S519N, Q520L, A554S M16I, E89K 
KE295198V5 KE295198V5 None None   K11T, V21I, V35T, T39K, K43E, V60I, K122E, D123G, K173A, Q174K, D177E, T200A, Q207E, V245K, D250E, A272P, L282C, L283I, T286A, A288T, I293V, R307K, S322A, K323R, G335D, P345Q, F346Y, A355T, R356K, R358K, A360T, E370A, T377Q, S379C, K390R, A400T, E413D, V417I, E432D, N447S, K476R, H483N, L491S, K512R, S519N, Q524K, K527G, A534S, A554S, V559I  
KE335214V6 KE335214V6 None None   K20R, V35T, V60I, D123S, I135T, K173L, Q174K, N175Y, T200A, Q207A, R211N, F214L, V245E, D250E, K281R, T286A, I293V, P294T, E312D, G335D, M357K, G359S, A360T, K366R, T369A, A371V, I375V, A376V, T377Q, E396D, A400T, E404D, E432D, V435A, A437V, Q480H, L491P, K512R, L517I, S519N, Q524K, K527E, E529D, V531I, A534S, A554N, V559I G262E, E438K, G555E 
KE344827V3 KE344827V3 None None   V35T, E36A, T39E, S48T, K122E, A158S, K173I, Q174K, G196E, T200A, Q207K, R211A, V245Q, P247A, A272P, K275R, K277R, T286A, E291D, V292I, I293V, E297P, G335D, R356K, M357R, G359T, T377Q, K390R, E404D, E432D, V435I, N447S, L452M, V466I, S468T, L469V, Q480L, H483Q, L491P, S519N, K527N, K530R, A534S, A554N  
KE354207V3 KE354207V3 None None   E6D, K11T, K20R, V21I, V35T, T39K, V60I, D121Y, K122E, D123G, K173S, Q174K, D177E, V179I, T200A, I202V, Q207A, R211N, V245Q, E248D, K281R, L283I, E291D, V292I, I293V, E312N, G335D, M357K, A360T, K366R, T369A, A371V, I375V, A376V, T377L, S379G, A400T, T403M, E404D, E432D, V435L, D471E, K476Q, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, A534S, A554S R358N, G359R 
KE369195V4 KE369195V4 None None   E6D, K11Q, V35T, T39E, S48T, K122E, D123N, I142V, K173A, Q174K, D177E, T200A, Q207A, R211K, F214L, V245Q, E248D, A272P, E291D, V292I, I293L, V317A, Q334N, G335D, R356K, M357R, G359T, K366R, T369V, A371V, I375V, T377Q, K390R, T403I, E404D, V435L, L452M, V466I, T470P, D471E, T477A, H483Q, L491P, V493A, E516D, S519C, K530R, A534S, A554S  
KE376579V4 KE376579V4 None None   V35T, V60I, K122E, D123G, I135T, K173S, Q174K, D177E, V179I, T200A, Q207G, T286A, E291D, V292I, I293V, P294T, E312D, G335D, E344D, M357K, G359S, K366R, T369A, E370D, A371V, I375V, A376V, T377M, K388R, A400T, T403M, E404D, V435L, D471E, Q480H, L491S, K512R, S519N, Q524K, K527G, E529D, A534S, A554S  
KE378531V2 KE378531V2 None None   V35T, T39R, E40D, V60I, K122E, D123S, I135T, S162A, K173A, Q174K, D177E, V179I, I202V, Q207D, F214L, V245E, D250E, K277R, K281R, T286A, E291D, V292I, I293V, P294T, G335D, R356K, M357K, G359S, A371V, I375V, A376V, T377I, A400T, T403M, E404D, V435M, D471E, Q480H, G490E, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554S  
KE389016V3 KE389016V3 None None   P4S, V35T, K122E, D123N, I135T, I142V, D177E, I178M, T200A, E204K, Q207E, R211K, P243S, V245K, V276I, K281R, T286A, E291D, V292I, I293V, P294T, E297R, A304E, G335D, R356K, M357K, G359S, A360T, K366R, V372I, T377M, T386I, K390R, A400T, V435L, A446S, S468P, T470A, D471E, Q480H, H483Y, L491S, K512R, S519N, Q520K, Q524K, K527E, K530R, A534S, A554S  
KE398838V4 KE398838V4 None None   V8I, P14T, V35T, T39R, D121Y, K122E, D123E, K166R, K173S, I202V, Q207E, V245Q, K275R, T286A, E291D, V292I, I293V, L295M, E297R, A304E, E312N, G335D, R356K, M357K, R358K, G359S, A360T, T386I, K390R, Q394L, E399D, A400T, T403I, V435A, A437V, R461K, D471E, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527E, A534S, A554T, K558R  
KE404877V7 KE404877V7 None None   K11M, V35T, V60I, R83K, D121Y, K122E, D123G, I142V, K173S, Q174K, D177E, I178L, V179I, G196R, Q207A, R211S, V245T, D250E, A272P, T286A, V292I, I293V, P294T, L295M, E312D, Q334P, G335D, R356G, M357R, R358K, G359S, K366R, I375V, T377L, A400T, T403M, E404D, P421L, E432D, V435I, A437V, V458I, K465R, D471E, Q480Y, L491S, S519N, K527G, E529D, A534S, A554S  
KE406723V2 KE406723V2 None None   E6D, K11T, V35T, V60I, D121H, K122E, D123S, I135T, K173A, Q174R, D177E, I178V, V179I, Q207A, R211S, F214L, D250E, A272P, T286A, E291D, V292I, I293V, P294T, E312D, G335D, M357K, R358K, G359A, K366R, T369A, A371V, I375V, A376V, T377M, T386A, K390R, A400T, T403M, E404D, E432D, V435A, A437V, D471E, Q480H, L491S, K512R, L517I, S519N, Q524K, K527E, E529D, K530R, A534S, A554S  
KE414659V2 KE414659V2 None None   V35T, V60I, K122E, D123S, I135T, K173A, Q174K, D177E, I178L, V179I, G196E, Q207T, R211S, V245K, D250E, K281R, T286A, E291D, V292I, I293V, P294T, K311R, E312D, G335D, M357K, G359S, T369A, A371V, I375V, T377M, A400T, T403V, E404D, E432D, V435A, E449G, D471E, Q480H, H483Y, L491S, K512S, E514D, L517I, S519N, Q524K, K527E, E529D, K530R, A534S, A554S  
KE452693V6 KE452693V6 None None   K11E, L34I, V35T, V60I, D121H, K122E, D123S, I135T, T165I, K173S, Q174K, V179I, I195K, G196E, I202V, Q207A, R211N, V245Q, D250E, T286A, E291D, V292I, I293V, P294T, E312N, G335D, M357K, G359S, K366R, T369A, A371V, I375V, T377M, T386A, A400T, T403M, E404D, E432D, V435E, D471E, Q480H, H483Y, L491S, S519N, Q520L, Q524K, K527E, E529D, V531I, A534S, A554S, K558R  
KE484390V7 KE484390V7 None None   V35T, V60I, K122E, T139K, K173S, Q174K, D177E, Q207A, R211K, F214L, V245I, E248N, A272S, T286A, G335D, P345T, M357N, G359S, T369A, A371V, I375V, T377R, S379C, T386I, K390R, K395R, A400T, T403M, E404D, E413D, E432D, K465R, V467I, T470A, D471E, Q480H, H483K, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554S  
KE489686V2 KE489686V2 None None   V35M, V60I, D121Y, K122E, I135T, D177E, T200I, Q207E, R211K, P243S, V245E, D250E, S251C, A272S, K277R, L282C, L283I, V292I, I293V, E297A, K311R, G335D, P345Q, F346H, R356K, A360T, T377L, K385R, K390R, A400T, F416Y, E432D, V435A, F440Y, A446S, K454R, D471E, Q480H, H483Y, L491S, Q524E, K530R, A534S, A554N  
KE493170V5 KE493170V5 None None   V35T, T39K, D121H, K122E, D123N, I135T, D177G, Q207E, R211K, V245K, A272S, T286A, E291D, V292I, I293V, E297K, A304E, E312D, R356K, M357R, R358K, G359A, A360T, K366R, T377Q, K390R, A400T, E432D, V435E, L452Q, V458I, R461K, S468T, D471E, Q480H, H483Y, V496I, A502V, K512Q, S519N, Q524K, K527E, K530R, V531I, A534S, A554S Y127F 
KE520997V4 KE520997V4 None None   K32Q, V35T, E36N, V60I, K122E, D123S, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, E248Q, D250E, K275Q, T286A, E291D, V292I, I293V, P294T, E312D, G335D, M357R, G359S, T369V, A371V, I375V, A376V, T377M, A400T, T403M, E404D, E432D, V435E, K451Q, V467I, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, A534S, A554S  
KE530245V4 KE530245V4 None None   V35T, V60I, K122E, D123N, I135T, I142V, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, V245K, D250E, A272P, K281R, T286A, E291D, I293V, P294T, E312D, A327V, G335D, M357N, G359S, T369A, A371V, I375V, A376V, T377Q, A400T, T403M, E404D, E432D, V435I, L452Q, R463K, D471E, Q480H, H483Y, L491S, Q509T, K512R, S519N, Q520K, Q524E, K527G, E529D, A534T, A554S  
KE543869V2 KE543869V2 None None   V35T, E40D, K49R, V60I, D121Y, K122E, T200I, Q207E, R211K, I244V, V245E, A272P, K277R, Q278H, L282C, E297A, K311R, G335D, P345Q, F346Y, K347R, R356K, G359S, A360T, T377Q, S379C, K390R, A400I, E413D, H483N, S519N, A534S, A554S, V559I  
KE556528V2 KE556528V2 None None   V35T, K49R, V60I, K122E, D123N, D177E, I178M, T200I, Q207D, R211K, V245K, D250E, A272S, K277R, L282C, L283I, T286A, I293V, P294A, E297A, I329L, G335S, P345Q, F346Y, R356K, A360T, T377Q, K390R, A400T, V458I, R461K, H483N, S519N, Q524E, A534S, A554N, V559I  
KE585573V2 KE585573V2 None None   V35A, E36A, T39E, S48T, K122E, D123N, I142V, K173A, G196V, T200A, Q207E, R211K, D250E, S251D, A272P, K275Q, K277R, Q278H, E291D, V292I, I293V, Q334N, G335D, R356K, G359T, A376S, T377M, K390R, A400T, E404D, E432D, I434M, A437V, L452K, V467I, S468P, D471E, T477A, H483Q, L491S, S519N, K527Q, K530R, A534S, A554S  
KE607907V4 KE607907V4 None None   V35T, E40D, K49R, V60I, K64R, D121H, K122E, I135T, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, P243S, V245K, E248D, D250E, T286A, E291D, V292I, I293V, P294T, Q334H, G335D, M357K, G359S, K366R, T369A, A371V, I375V, A376V, T377L, S379A, K388R, A400T, T403M, E404D, E432D, D471E, Q480H, H483Y, L491S, Q520L, Q524K, K527G, E529D, A534S, K558R  
KE613437V4 KE613437V4 None None   V35T, E36A, V60I, K173R, D177E, I178M, E194K, T200I, Q207E, R211K, D237N, V245I, E248D, D250E, L282C, R284K, T286V, I293V, G335D, P345Q, F346Y, R356K, A360T, T377Q, S379C, K390R, A400T, V435A, R461K, Q464K, V466I, V467I, H483N, L491S, E492K, S519N, A534S, A554N, V559I E89K, E413K, D443N 
KE629642V3 KE629642V3 None None   K11T, V21I, V35T, V60I, D123N, I135M, K173A, D177E, I202V, Q207A, R211S, V245E, D250E, K281R, T286A, E291D, V292I, I293V, E312N, G335D, M357K, G359S, I375V, T377L, K390R, A400T, T403M, E404D, E413D, E432D, D471E, L491S, K512R, S515A, L517V, S519N, Q520E, Q524K, K527E, E529D, A534S, A554S  
KE643439V4 KE643439V4 None None   E6D, V21I, V35T, K43N, V60I, K122E, D123S, I142T, K173S, Q174K, D177E, I178L, V179T, T200A, Q207A, R211N, V245E, D250E, A272P, T286A, I293V, P294T, E312D, G335D, F346H, R356K, M357Q, G359S, T369A, A371V, I375V, A376V, T386A, K395R, A400T, T403M, E404D, E432D, V435A, K465R, V467I, D471E, Q480H, H483Y, L491S, K512R, E514D, S519N, Q524K, K527G, E529D, A534S, A554S  
KE649309V2 KE649309V2 None None   V35T, E40D, K49R, V60I, D121H, K122E, I135T, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, E248Q, D250E, T286A, E291D, V292I, I293V, P294T, E312D, G335D, F346H, M357R, G359S, T369A, A371V, I375V, A376V, T377M, A400T, T403M, E404D, E432D, R448K, V467I, S468N, D471E, Q480H, H483F, L491S, K512R, E516G, S519N, Q520E, Q524K, K527G, E529D, A534S, A554S  
KE661996V6 KE661996V6 None None   V35T, E40D, K49R, I50V, V60I, T69S, D121H, K122E, I135T, E169D, K173S, Q174K, D177E, V179I, G196E, T200I, Q207A, R211S, F214L, V245E, D250E, K277R, T286A, A288G, I293V, P294T, K311R, E312H, Q334K, G335D, M357K, G359S, K366R, T369V, A371V, I375V, A376T, A400T, T403M, E404D, E432D, V435I, D471E, Q480H, L491S, K512R, E514D, Q524K, K527E, E529D, A554N  
KE663257V3 KE663257V3 None None   K11T, K20R, V21I, V35T, T39K, S48X, V60I, D123S, K173S, D177G, V179I, T200A, I202V, Q207A, R211S, V245Q, E248T, T286A, E291D, I293V, P294T, E312D, G335D, M357K, G359S, A371V, I375V, T377M, I393L, T403M, E404D, E432D, V435I, D471E, Q480H, L491S, K512R, L517I, S519N, Q524K, K527E, E529D, A534S, A554S, V559I  
KE688699V6 KE688699V6 None None   V35T, E36A, T39E, E40D, K43R, V60I, K122E, D123S, I135T, S162C, K173S, Q174K, D177E, I178L, V179T, T200I, Q207A, R211S, V245K, D250E, A272P, L282C, I293V, G335D, P345Q, F346Y, R356K, M357T, A360T, I375V, T377Q, S379C, K390R, A400T, A446S, L452I, L469I, H483N, L491V, S519N, A534S, V548I, A554N, V559I  
KE719832V2 KE719832V2 None None   K11T, V35T, E40D, K43R, V60I, K122E, D123S, I135T, K173L, Q174K, D177E, V179I, G196E, T200S, Q207A, R211S, V245K, D250E, K277R, T286A, E291D, V292I, P294T, E297K, A304E, E312D, I329V, G335D, M357K, G359S, T377V, K390R, A400T, T403M, E404D, E432D, V435A, A437V, D471E, Q480H, H483Y, L491S, I506L, K512S, L517I, S519N, Q524K, K527E, E529D, A534S, A554S  
KE725124V4 KE725124V4 None None   V35T, T39R, G45E, K49R, D121Y, K122E, D123G, S162C, D177E, Q207E, R211K, V245E, T286A, E291D, V292I, I293V, E297K, A304E, E312D, D324E, G335D, R356K, M357K, R358K, G359S, A360T, K366R, A376S, T377M, T386I, K390R, E396D, A400T, E404D, V435A, A437V, V466I, S468P, D471E, H483Y, E514D, S519N, Q524K, K527E, A554S  
KE726081V5 KE726081V5 None None   V35T, T39R, E40D, K102R, D121Y, K122E, I135R, D177E, T200A, Q207E, R211K, F214L, V245K, K281R, T286A, V292I, I293V, P294T, E297K, A304E, E312D, S322A, G335D, M357R, G359A, A371V, I375V, A376V, T377L, T386I, A400T, T403M, E404D, E432D, Q480H, L491S, I495V, K512R, S519N, Q524K, K527G, E529D, A534S, A554S E291G 
KE757760V5 KE757760V5 None None   E6A, V35T, E36A, T39E, K122E, D123S, I135T, K173S, T200A, Q207E, V245H, A272P, K281R, T286A, E291D, V292I, I293V, P294T, E312D, I326T, Q334P, G335D, M357K, G359S, K366R, T369A, A371V, I375V, A376V, T377M, A400T, T403M, E404D, E432D, V435A, N447S, D471E, Q480H, L491S, K512R, L517I, S519N, Q524K, K527G, E529D, A534S, A554M R143G 
KE780221V3 KE780221V3 None None   V35T, T39R, D123N, T139I, K173S, D177E, V179I, Q207D, L210F, R211S, F214L, V245Q, E248D, Y271H, T286A, E291D, I293V, P294T, E312D, V317A, G335D, M357Q, G359S, A371V, I375V, A376V, T377Q, K395R, A400T, T403R, E404D, E432D, V466I, D471E, K476R, Q480H, H483Y, L491S, K512R, Q524K, K527G, E529D, A534S, A554S  
KE795643V7 KE795643V7 None None   V21I, T27S, V35T, E40D, V60I, K122E, D123N, I135T, S162A, K173S, Q174R, D177E, V179I, Q207A, R211S, I244M, V245E, D250E, K281R, T286A, K287R, I293V, P294T, E297K, E312D, G335D, A355G, M357K, G359S, A371V, I375V, A376V, T377M, A400T, T403M, E404D, E432D, L452Q, D471E, Q480H, L491S, K512R, S519N, Q524K, E529D, K530R, A534S, A554S  
KE809646V6 KE809646V6 None None  K103N V35T, K49R, V60I, K64R, V90I, T200A, Q207E, R211K, V245N, D250E, A272P, K277R, L282C, L283I, I293V, D324E, Q334N, G335D, P345Q, F346Y, R356K, M357V, A360T, I375A, T377Q, S379C, K390R, T403M, E404N, K431T, E432D, V435P, A437V, R461K, D471E, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527E, E529D, K530R, V531I, A554S, V559I  
KE809842V2 KE809842V2 None None   V35T, T39L, V60I, K64R, D123S, I135T, K173L, Q174K, D177E, V179I, T200A, Q207A, R211N, V245M, E248D, D250E, K277KR, K281R, T286A, E291D, I293V, P294T, K311R, G335D, F346L, M357K, G359S, K366R, T369A, A371V, A376V, T377L, T386A, E396D, A400T, T403M, E404D, E432D, A446S, D471E, K476Q, T477A, Q480H, L491S, D511N, K512N, S519N, Q524K, K527G, E529D, V531I, A534S, A554S  
KE830543V3 KE830543V3 None None   P14S, V35T, K49R, V60I, D121Y, K122E, D177E, I178M, T200I, Q207E, R211K, V245N, D250E, A272P, K277R, L282C, T286A, A288T, I293V, G335D, P345Q, F346Y, A355T, R356K, A360T, E370A, T377Q, S379C, K390R, E399D, A400T, V435E, L452I, H483N, L491S, K512T, S519N, Q524E, K527R, E529D, A534S, E546D, A554N, V559I  
KE851891V4 KE851891V4 None None   V21I, T27S, V35T, E40D, V60I, K122E, D123N, I135T, S162A, K173S, Q174R, D177E, V179I, Q207A, R211S, V245E, D250E, T286A, K287R, I293V, P294T, E297K, E312D, G335D, A355G, M357K, G359S, A371V, I375V, A376V, T377M, A400T, T403M, E404D, E432D, L452Q, D471E, Q480H, L491S, K512R, S519N, Q524K, E529D, K530R, A534S, A554S  
KE860822V3 KE860822V3 None None   K20R, V35T, T39K, K122E, D123G, K173S, D177G, T200A, Q207A, V245E, K281R, T286A, V292I, I293V, E297K, E312D, G335D, M357R, G359S, T369A, A371V, I375V, A376V, T377L, A400T, T403M, E404D, Q428H, E432D, N447S, D471E, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, V548A, A554S, V559I  
KE870929V2 KE870929V2 None None   P4S, K20R, V35T, T39E, S48E, D123E, I135R, S162C, D177E, I178IM, T200A, Q207E, V245H, D250E, K277R, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, T377M, K390R, A400T, E404D, V435I, L452V, L469I, D471E, H483Q, L491S, S519N, K530R, A534S, A554S  
KE880505V2 KE880505V2 None None   V35T, T39S, V60I, D121Y, K122E, I135T, K173L, Q174K, D177E, V179I, G196E, Q207A, R211S, S251H, T286A, E291D, V292I, I293V, E297K, V317A, D324E, G335D, M357K, G359S, K366R, T369A, A371V, I375V, A376V, T377M, S379G, K395R, A400T, T403M, E404D, W410C, E413D, E432D, V435A, D471E, Q480H, L491S, K512R, L517I, S519N, Q524K, K527E, E529D, A534S, A554S  
KE884468V5 KE884468V5 None None   K20R, V35T, E36D, T39A, V60I, K122E, D123S, I135T, I142V, K173A, Q174K, D177E, V179I, T200A, Q207A, R211S, V245Q, D250E, T286A, E291D, V292I, I293V, P294T, E312D, A327V, G335D, M357K, G359S, A371V, I375V, A376V, T377L, T386I, K390R, A400T, T403M, E404D, E432D, V435M, K451R, D471E, Q480H, H483Y, L491P, K512R, S519N, Q524K, K527G, E529D, K530R, A534S, A554S  
KE888800V3 KE888800V3 None None   E6R, V35T, K49R, V60I, D121Y, K122E, I135T, S162A, K173N, Q174R, D177E, I178M, Q207A, R211K, V245K, D250E, A272P, K277R, Q278Y, K281R, L282C, T286A, V292I, I293V, G335D, P345Q, F346Y, R356K, R358K, T377Q, S379C, K390R, Q394L, A400T, S468P, H483K, E529D, A534S, A554N, V559I  
KE894822V7 KE894822V7 None None   V21I, V35T, T39A, E40D, V60I, K122E, D123S, I135T, D177E, I178M, Q207E, R211K, V245M, E248D, D250E, A272S, T286A, E291D, V292I, I293V, P294T, E312D, V314A, G335D, R356K, M357K, G359S, A371T, I375V, T377L, T386I, A400T, T403V, E404D, E432D, D471E, Q480Y, L491S, K512R, S519N, Q524K, K527G, E529D, A534S, A554S  
KE897156V5 KE897156V5 None None   V21I, V35T, K49R, V60I, V90I, K122E, I135V, E169K, D177E, I178M, T200I, Q207E, R211K, V245K, A272S, L282C, L283I, T286A, V292I, I293V, G335D, P345Q, F346Y, R356K, M357L, A360T, T377Q, S379C, K390R, E396D, A400T, K431T, V435A, H483N, S519Q, K527G, A534S, A554N, V559I  
KE956490V3 KE956490V3 None None   V35T, E40D, K49R, V60I, I135M, D177E, I178V, V179A, T200I, Q207E, R211K, L228M, V245H, D250E, A272S, L282C, L283I, R284K, A288S, I293V, L310I, S322A, D324E, L325I, G335D, P345Q, F346Y, R356K, R358K, G359S, T377Q, S379C, K390R, A400T, N418H, V435A, A437V, V466I, Q480H, H483F, E492D, K530R, A534S, A554N, V559I  
KE961896V5 KE961896V5 None None   V35T, T39R, K43E, K122E, I135T, D177E, I178M, Q207E, R211K, V241I, V245M, E248D, D250E, I257L, A272S, L282C, T286A, I293V, K323R, G335D, P345Q, F346Y, R356K, M357S, A360T, T377Q, T386I, K390R, A400T, E415D, V435T, R461K, V467I, H483N, L517I, S519N, Q524K, K527G, K530R, A534S, A554S  
KE963379V4 KE963379V4 None None   V35T, V60I, D121H, K122E, D123E, I142V, Q207E, R211K, V245Q, D250E, A272S, I293V, E312N, P313T, G335D, M357R, G359S, T369A, A371V, I375V, A376V, T377M, K388R, A400T, T403M, E404D, E432D, V435A, D471E, Q480H, H483Q, L491S, L517I, S519N, Q524E, K527G, E529D, A534S, A554Q