<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Rokx (2015)
Title Increased virological failure in naive HIV-1-infected patients taking lamivudine compared with emtricitabine in combination with tenofovir and efavirenz or nevirapine in the Dutch nationwide ATHENA cohort.
Citation Clin Infect Dis
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 68
NumPts 68
Subtype B, CRF02_AG, C, CRF01_AE, F, A, CRF07_BC, CRF18_cpx, CRF06_cpx

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
M14535 M14535 TDF, 3TC NVP M41L, K65KR, M184V, T215D Y181C V60I, I135T, I202V, L210F, R211K, S251H, A272P, K277R, A288S, V292I, I293V, E297A, S322T  
M14941 M14941 TDF, 3TC NVP K65R G190S D123E, K166R, I178M, V245K, A272P, K277R, K281R, T286P, E297K, Q334E  
M25671 M25671 TDF, FTC EFV   P4T, I135V, S162C, K201KI, R211K, T286A  
M26251 M26251 TDF, 3TC NVP D67N, K70KN, M184MI Y181C E6D, V35T, T39K, K43E, T69A, K122E, D123S, I135T, A158T, R172K, K173I, Q174K, D177E, T200I, Q207A, K238R, V245E, V276I, K281R, T286A, E291D, V292I, I293V, E312T  
M28208 M28208 TDF, FTC EFV  K103N V35T, T39L, V60I, I135T, K173L, Q174K, D177E, V179I, Q207A, R211S, V245K, D250E, A272P, K281R, T286A, E291D, I293V, P294T, D320N, S322L  
M28442 M28442 TDF, 3TC NVP K65KR K103KN, V108I V35I, S68G, V90VI, A98S, K122P, D123E, I135V, A158S, D177E, I178L, V245M, E291D, P294A, I326V, I329V, Q334E L210A 
M28529 M28529 TDF, 3TC NVP M184I Y188C I50V, V106I, I135T, V179VI, R211K, V245K, I293V, E297Q, V317G  
M28585 M28585 TDF, FTC EFV K65R G190C V35T, E36A, T39E, E40D, S48T, K101KQ, K122E, K173T, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, K311R  
M29366 M29366 TDF, FTC NVP K70KE, M184MIV K101KE, V179VD, Y181C K20R, K103KR, K122R, D123E, Q174L, I178IM, T200E, R211Q, F214L, H221HY, L228LR, V245K, S251I, I293V, E297EA, I329L, Q334D  
M29970 M29970 TDF, 3TC NVP   P4H, V35T, T39S, K64R, K122E, I135V, S162A, T165I, K173T, Q174K, D177E, I178IM, T200A, Q207E, V245Q, T286A, I293V, P294T, S322T, I326V D192DY 
M30171 M30171 TDF, FTC NVP K65R, M184V K103KN, V108VI, Y181C K43R, K102KR, I135M, V189I, T200A, Q207E, F214L, D237DE, V245EK, I293V  
M30219 M30219 TDF, 3TC NVP K65R V106A, F227L V60I, D123E, I135T, K173Q, D177E, T200E, D250E, A272P, K277R  
M30224 M30224 TDF, 3TC NVP A62V, K65R, M184V K101KE, Y181C, G190GA P9PS, K20KR, I135IT, S162C, Q174K, I178L, V179I, G196GE, Q207E, R211K, V245E, D250E, A288S, I293V, E297A, E312Q, Q334N  
M30475 M30475 TDF, 3TC EFV  K103KN V35VI, S162C, I178L, Q207E, R211K, I244IV, V245VM, E248ED, D250DE, A272T, I293V, E297EAPQ, K311R, E312T, Q334N  
M30577 M30577 TDF, FTC NVP M184I Y188L, G190A K173Q, T200V, F214L, D237N, I244V, D250E, K277R, I293V, E297P  
M30601 M30601 TDF, FTC EFV M184V A98AG, K103N, V179VE, P225PH V35T, E36D, T39M, V90VI, S162A, K173T, Q174K, D177E, I178M, T200A, E204ED, Q207AEG, R211RKNS, V245Q, A272P, K281KR, R284K, T286A, E291DN, V292I, I293V, P294A  
M30638 M30638 TDF, 3TC EFV K65KR, M184MV V106M, V179D V35I, E36A, T39E, S48T, D121H, K122E, D123S, I135M, S162C, T165A, K173R, Q174K, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, P294Q  
M30701 M30701 TDF, 3TC EFV M184MIV K103N, K238T V35T, T39A, D123E, I135L, S162C, K173I, Q174K, I178L, T200L, Q207A, R211T, V245Q, E248D, A272P, K277R, L283I, T286A, E291D, V292I, I293V, E297T, V317A  
M30811 M30811 TDF, FTC EFV K65R, L74V G190E K20R, V60I, R83K, R211S, A272P, K277R, Q334L  
M30932 M30932 TDF, 3TC EFV   K102KR, I135T, S162W, I167F, K173Q, T200A, Q207G, R211T, D237DA, V245VM, E248N, A272P, T286A, I293V  
M31056 M31056 TDF, FTC EFV M41L, T215C K103KN, G190GA K20R, K122P, D123E, I135T, K166KR, D177E, I178IV, V189I, A272P, K277KR, I293V, P294Q  
M31277 M31277 TDF, FTC EFV D67G, K70R, M184V, T215C, K219E K103N K20R, V60I, S68G, K122KE, I135T, I178M, A272P, K277R, L283I, A288T, V292I, I293IV, E297Q, I326V, I329V, Q334H  
M31351 M31351 TDF, 3TC EFV K65KR, M184MV G190S V8I, V35I, R83K, G196E, E203K, R211K, A272P, K275R, I293V, K311R  
M31400 M31400 TDF, FTC EFV L74LIV, Y115F, M184V V106M, V179D, F227L V35T, E36A, T39E, S48T, V60I, V90I, Q145C, E169D, K173A, Q174K, T200A, Q207E, R211K, V245Q, E248N, A272P, K277R, T286A, E291D, V292I, I293V  
M31633 M31633 TDF, 3TC EFV   V35I, D123E, Q207K, R211A, S251T, K277R, I293V, P294Q, S322T, D324E, G333E  
M31798 M31798 TDF, 3TC EFV M41L, K65R, L210W, T215D, K219R A98G, L100LIV, K103N, V108VI, V179DE, Y181YC E6EA, K20R, V35I, K43N, I178V, G196E, I202V, R211K, A272P, K275Q, K277R, V292I, P294A, E297K, I329L  
M31806 M31806 TDF, FTC EFV   V35K, T39A, A62T, D123E, S162A, T165TI, K173T, Q174K, D177E, V189I, Q197E, T200A, I202V, Q207E, P225PS, V245Q, T286A, E291D, I293V, P294IV, E312Q, S322T, I326V  
M32099 M32099 TDF, 3TC EFV K65KR, D67DG, L74LV, K219KN G190E K22R, V35I, R83K, D123E, I135T, D177E, Q207N, R211K, A272P, I293V  
M32188 M32188 TDF, 3TC NVP T69D, M184MIV V106VA, Y181YC I5IV, V35VI, T39A, A62AT, D123E, E169ED, I202V, H208Y, R211K, L228LR, A272P, K277R, I293V, S322T  
M32271 M32271 TDF, FTC NVP K65KR Y181YC K32R, L109LM, D123E, I142V, S162Y, D177E, I178L, V179I, T200A, Q207G, R211K, V245K, K249Q, A288S, I293V, Q334D  
M32457 M32457 TDF, FTC EFV D67N, K70R, M184V, T215I, K219E A98G, K103N, P225H E6D, K43KR, I135M, R211K, A272G, A288S, I293V, D324E  
M32508 M32508 TDF, 3TC NVP K65R V106VA, Y181C D123E, I142V, T165I, I178M, I202V, V245E, K277R, T286A, I329L  
M33168 M33168 TDF, 3TC EFV M184V K101E, G190S V35I, I135T, K173T, Q174R, T200A, Q207A, R211K, V245Q, I293V, D324E, I329L  
M33253 M33253 TDF, FTC EFV   V35R, D123E, D177E, Q207N, R211K, K277R, I293V, E297K, I326V, Q334E  
M33262 M33262 TDF, 3TC NVP M184I V106A, F227L S162C, T200A, Q207E, R211K, V245K, A272P, E291A, I293V, Q334L  
M33316 M33316 TDF, 3TC NVP L74LV V106A K122E, D123E, I135T, T200A, R211K, F214L, A272P, T286A, E297K, Q334H  
M33647 M33647 TDF, FTC EFV D67N, K70R, M184V, K219Q K103N, P225PH, K238T V35IMT, V60VI, K122E, E138Q, S162C, K173KR, I178M, T200A, E203K, Q207E, F214L, T286A, A288S, I293V, G333E, Q334H  
M33715 M33715 TDF, FTC EFV   K20R, K64KR, K122AEPQ, D123DGNS, K166R, D177DE, I178IM, T200TA, R211K, I257L, K277R, T286A, I293V, E297K  
M33822 M33822 TDF, 3TC NVP K65KR, M184MI K101KE, V106VM, Y181YC, G190GA V35T, E36A, T39D, E44D, K122E, D123S, I135L, T139TK, S162C, K173A, Q174K, D177E, I178IL, V179VI, T200A, Q207E, R211K, V245Q, E248D, A272P, T286A, E291D, I293V, D324DE  
M33867 M33867 TDF, FTC EFV  K103N V35T, E36ED, T39M, I135T, S162A, K173T, Q174K, D177E, T200A, Q207E, V245KLMQ, D250DGNS, K281R, T286A, E291D, I293V, P294A, S322T  
M33920 M33920 TDF, FTC NVP K65R, M184I Y181C I31L, V35I, V90I, I142V, K166R, K173Q, T200E, V245T, A272S, K275KQ, V276I, L283I, I293V, E297A  
M34134 M34134 TDF, FTC EFV M41L, L74V, M184V, T215D L100I, K101H, G190A T39A, V90VI, K122E, D123S, E204D, R211K, E248ED, A272P, L283I, I293V, E297R, H315Q, G333D, Q334Y G155GR 
M34288 M34288 TDF, FTC NVP A62AV, K65R, M184IV V108VI, Y181C R83K, V90VI, K122P, I135IL, D177E, I178L, Q207E, H221HY, A272S, A288S, I293V  
M34459 M34459 TDF, FTC EFV   I50IV, I135IM, S162C, V189VI, Q207K, R211S, A272S, K277R, I293V, E297EG, R307RK, P313T, V317A  
M34641 M34641 TDF, FTC NVP M184I K103KN, Y181C K20R, V90VI, D123E, I135T, S162C, I178L, R211K, F214L, V245E, A272S, V276I, T286A, V292I, I293V, Q334E  
M34706 M34706 TDF, FTC EFV  K103KN V35T, E36A, T39D, S48T, V60I, D121HY, K122E, I135IM, T165TI, E169ED, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, V317VA  
M34723 M34723 TDF, FTC NVP A62AV, K65N, M184MV V108VI, Y181C K49R, A98S, T165I, D177E, K277R, T286A, A288S, E297K, P321S, D324E K66KQ 
M34804 M34804 TDF, FTC NVP M184I K103KN, Y181C V21I, V35T, V60I, K122P, D123E, Q174E, D177E, Q207A, R211K, H221HY, V245Q, A272S, T286A, E291D, V292I, I293V, E297A  
M34867 M34867 TDF, FTC EFV   K11T, V35T, T39K, K43E, V60I, S68G, V106I, V118VI, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, K277R, T286A, E291D, V292I, I293V, E312S, P313T, I326V, I329V E89EK 
M34934 M34934 TDF, FTC EFV   I50IV, L100LV, K102KR, I142V, S162C, Q207QR, R211K, V245T, K277R, T286TA, A288AS, V292VI, I293IV, P294PS, L295LF, E297K  
M35241 M35241 TDF, FTC NVP K65R, V75IM V106A, Y181C P4S, K20R, V21I, V35T, E36DN, T39I, K66R, V90I, K122E, I135V, S162A, K173A, Q174K, D177E, I178M, T200A, R211K, V245Q, E248D, D250E, A272P, K275R, Q278H, T286V, E291D, V292I, I293V, E297V, P321A, S322A, D324E, I329V  
M35704 M35704 TDF, FTC EFV D67G, M184V K101KEQ, G190S V35I, D123E, I135M, K166R, D177E, G196E, D250E, E297K, P313Q, S322T, Q334N  
M35727 M35727 TDF, FTC EFV   V35I, I135T, T165I, I178M, R211A, K277R, P294Q, D324E  
M35824 M35824 TDF, FTC NVP   K11R, V35VI, D121Y, K122E, K166R, P176PS, D177DE, I202IV, R211K, A272G, K277R  
M36366 M36366 TDF, FTC EFV   D121HY, K122E, I135T, S162C, D177E, I178V, G196E, T200A, Q207E, V245VI, A272P, I293IV, Q334C  
M36620 M36620 TDF, FTC EFV M184V K103N, V108VI, P225H K122E, S162C, G196E, Q197K, E203D, Q207D, R211K, A272P, V317T, S322T, I329L  
M37008 M37008 TDF, FTC EFV   K104N, D123E, S162SC, G196E, T200A, Q207K, R211A, A272P, K277R, T286A, V292I, I293V, E297R, L301I  
M37062 M37062 TDF, FTC NVP K65R, M184V V179D, Y181C K11R, V35T, T39A, E40D, S68G, K103R, K122E, I135T, S162D, K166KR, G196E, F214L, A272P, V276I, V292I, I293V, E297A, I326V, I329L  
M37601 M37601 TDF, FTC NVP K65R, M184V K103N, Y181C V35I, K64KR, I135T, S162C, I178L, T200A, Q207E, R211K, E248D, A272P, K277R, E297K, I326V, Q334L T58TA 
M38000 M38000 TDF, FTC EFV D67N K103N, V106A, P225H K22R, V35T, K122E, I135V, S162A, K173T, Q174K, D177E, I178V, G196E, T200A, I202V, Q207G, F214L, V245Q, A272P, K281R, T286A, E291D, V292I, I293V, P294T, S322A, I326V, I329V K66I 
M38090 M38090 TDF, FTC EFV   V35M, D123E, D177E, T200A, R211K, A272P, V276I, K277R, L283I, I293V  
M38543 M38543 TDF, FTC EFV   V35T, T39M, V60I, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245K, S251I, T286A, K287R, E291D, I293V, P294T Y127YH 
M38669 M38669 TDF, FTC NVP K65KR, T215TA V106VA, Y181YC, G190GA K49KR, K122E, I135T, T200TI, I202V, F214FL, V245T, A272P, I293V, I326IV  
M38773 M38773 TDF, FTC EFV D67N, T215FLPS, K219Q K103N K20KR, K49R, V60I, D123E, D177E, G196E, I202V, R211K, V245E, A272P, T286A, V292I, I293V, Q334L  
M38951 M38951 TDF, FTC NVP M184I Y181C V35M, T39A, S48E, Q174H, T200A, E203K, Q207E, R211K, F214L, V245Q, E248D, A272P, V276VI, K277KR, E297A, S322T, I326V  
M40679 M40679 TDF, FTC NVP A62V, K65R, M184I Y181C V90I, K101Q, D123E, I135T, S162Y, I178M, V245E, A272P, K277R, T286A, E291D, E297K, I329L, Q334E  
M40995 M40995 TDF, FTC NVP M184I Y181C V35T, T39A, K122E, I135T, I142V, K173E, Q174R, D177N, T200E, R211K, A272S, K277R, T286A, I329L  
M41236 M41236 TDF, FTC NVP T215S Y181YC, G190GA K20R, K104N, S162C, E169A, R211K, V245I, S251N, A272P, V276I, L283I, V292I, I293V, E297A