Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Anstett (2015)
Title Dolutegravir resistance mutation R263K cannot coexist in combination with many classical integrase inhibitor resistance substitutions.
Citation J Virol
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Lab
NumIsolates 8
Lab Parent Strain NL43


Lab IN Isolates : Susceptibility Data

IsolateINIMajorDRMsINIMinorDRMsMethodDrugFold Res.
143R Y143R  TZM-McGill DTG 1.1 
     TZM-McGill EVG 2.1 
     TZM-McGill RAL 10 
143R263K Y143R, R263K  TZM-McGill DTG 3.3 
     TZM-McGill EVG 6.5 
     TZM-McGill RAL 3.7 
148R Q148R  TZM-McGill DTG 0.1 
     TZM-McGill EVG >50 
     TZM-McGill RAL >50 
155H N155H  TZM-McGill DTG 0.1 
     TZM-McGill EVG 4.7 
     TZM-McGill RAL 6.1 
263K R263K  TZM-McGill DTG 2.0 
     TZM-McGill EVG 19 
     TZM-McGill RAL 0.5 
92Q E92Q  TZM-McGill DTG 0.7 
     TZM-McGill EVG 50 
     TZM-McGill RAL 2.8 
92Q263K E92Q, R263K  TZM-McGill DTG 1.4 
     TZM-McGill EVG >50 
     TZM-McGill RAL 2.4