Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Rossouw (2015)
Title Factors associated with the development of drug resistance mutations in HIV-1 infected children failing protease inhibitor-based antiretroviral therapy in South Africa.
Citation PLoS ONE
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 65
NumPts 65
Subtype C, CRF04_cpx


Clinical PR Isolates

MIV001 MIV001 LPV, RTV 159 I54V, V82A, L90M Q58E, G73T I15V, L19I, K20R, M36I, R41K, I62V, L63P, H69K, A71V, I93L  
RP003 RP003 LPV 94   T12S, I15V, L19I, M36I, L63P, H69K, L89M, I93L  
RP005 RP005 LPV 138 V82L  T12S, I15V, L19X, E35D, M36I, R41K, H69K, L89M, I93L G51R, G52S, D60DY 
RP020 RP020 LPV 42 M46I, I54V, V82A L10F T12S, I15IV, L19I, K20R, E35D, M36I, R41K, R57K, L63P, H69K, L89X, I93L  
RP025 RP025 PI    T12S, I15V, L19T, K20R, E35D, M36I, R41K, H69K, L89M, I93L R8RG, L23LF 
RP030 RP030 LPV 75   T12S, I15IV, Q18E, L19I, M36T, R41K, L63T, H69K, I93L  
RP031 RP031 LPV 102   L10M, T12S, I15V, L19I, N37S, R41K, L63V, I64L, H69K, L89M, I93L D60DY 
RP032 RP032 LPV 104   T12S, I13V, G16GE, L19I, K20R, M36I, R41K, D60E, H69K, L89M, I93L  
RP033 RP033 LPV 164  Q58E L19T, K20R, M36I, R41K, D60E, H69K, L89M, I93L  
RP034 RP034 LPV 174   T12S, I15V, L19I, M36I, R41K, H69K, T74S, L89M, I93L  
RP036 RP036 LPV 189   V11L, T12S, I15V, L19I, K20R, E35D, M36I, N37D, R41K, Q61QE, L63P, H69K, L89M, I93L  
RP038 RP038 LPV 89 M46MI, I50V, I54V, V82A  L10I, I15V, L19I, K20R, E35D, M36I, R41K, K55KR, Q61D, I66L, H69K, A71AV, L89M, I93L  
RP039 RP039 LPV 148 M46L, I54V, V82A L10F T12S, I15V, L19I, K20R, E35D, M36I, N37D, R41K, K55KR, I62IV, L63P, H69K, I72V, T74A, L89M, I93L  
RP043 RP043 LPV 111   T12P, L19I, E35D, M36I, R41K, H69K, T74S, L89M, I93L  
RP045 RP045 LPV 133 M46I, I54V, L76V, V82A Q58E L10I, I15V, L19I, K20R, E35D, M36I, R41K, D60E, Q61D, L63P, C67E, H69K, L89M  
RP051 RP051 PI    T12P, I15V, L19I, M36I, N37S, R41K, D60E, Q61E, L63P, C67F, H69K, K70KR, L89M, I93L  
RP053 RP053 LPV 63   L10V, I15V, L19I, E35D, M36I, R41K, K43R, H69K, T74S, L89M, I93L  
RP054 RP054 PI    K14KN, I15IV, L19I, T31TA, E35ED, M36I, N37NDEK, R41RK, Q61QDEH, H69K, I72IV, T74TS, L89M, I93L L33LS 
RP059 RP059 PI  M46ML, I54IV, V82VA  I15V, L19LI, K20KR, E35D, M36I, R41RK, L63LP, C67X, H69K, L89M, I93L  
RP061 RP061 PI  M46I, I54V, V82A L10F T12S, I15V, L19V, K20R, E35D, M36I, R41K, R57K, Q61X, H69K, L89M, I93L  
RP068 RP068 LPV 66  M46MV T12P, I15V, L19I, E35ED, M36I, R41K, I62IL, L63LI, H69K, L89M, I93L  
RP069 RP069 PI    L10M, L19T, M36I, N37E, R57K, H69K, I72V, L89M, I93L  
RP073 RP073 LPV 99  G73GC L19T, N37S, R41K, L63V, H69K, V77I, L89M, I93L  
RP074 RP074 LPV 47 V82A  T12S, I15V, L19T, M36I, N37S, R41K, L63P, H69K, I93L  
RP077 RP077 LPV 66   T12S, I15V, L19I, M36I, R41K, D60E, Q61E, L63P, H69K, L89M, I93L  
RP080 RP080 LPV 22   T12S, I15V, L19I, E35D, M36I, I62V, L63A, H69K, L89M, I93L L38L_DL 
RP081 RP081 RTV, LPV 63 V82A  L10IV, T12S, I15V, G16GE, L19I, K20R, E35D, M36I, N37ND, R41K, I62IV, L63AT, H69K, I93L  
RP083 RP083 RTV 55   I15IL, L19T, M36I, R41K, D60E, Q61E, I62V, L63P, H69K, L89M  
RP084 RP084 LPV 172   T12S, I15V, L19V, M36I, N37D, R41K, L63P, H69K, I93L  
RP085 RP085 RTV, LPV 218   G16E, E35D, M36I, R41K, D60E, I62V, L63P, H69K, I93L  
RP087 RP087 RTV, LPV 210   L10LI, M36I, R41K, D60E, Q61E, H69K, L89M, I93L  
RP088 RP088 RTV 32   T12S, I15V, L19I, M36I, R41K, H69K, V77VI, L89M  
RP089 RP089 RTV, LPV 152 V82M, L90M Q58E I15V, L19T, K20R, M36I, R41K, D60E, L63P, H69K, P79H, L89M, I93L  
RP090 RP090 LPV, RTV 41   T12S, I15V, L19I, M36MIL, N37K, R41IN, K45KR, D60E, Q61E, L63P, H69K, L89LM, I93L  
RP096 RP096 LPV, RTV 206   T12S, I15V, L19I, K20R, E35D, M36I, R41K, H69K, T74S, L89M, I93L  
RP099 RP099 LPV 121 M46I, I54V, V82A L10LF, L24LI, L33F, T74TP I13IV, K14KR, I15V, Q18E, L19IT, K20KR, M36L, R41K, Q61H, I62V, L63LP, H69K, L89I, I93L, L97LI  
RP102-1 RP102-1 PI  M46I, I54V, L76V, V82A  L10V, I15V, L19I, K20R, M36I, R41K, D60E, Q61E, I62V, L63P, H69K, I72IV, L89M, I93L  
RP103-1 RP103-1 LPV 91   L19I, E35D, M36I, R41K, L63PS, H69K, V77VI, L89M, I93L  
RP104 RP104 LPV 124 M46I, I50V, I54V, V82A  L10I, T12S, I15V, L19V, K20R, E35D, M36I, R41K, L63P, H69K, K70R, A71V, V77I, L89M, I93L T31TI 
RP106-1 RP106-1 RTV, LPV 45 I54V M46V I15V, L19I, K20R, E35D, M36I, N37D, R57K, H69K, L89M, I93L  
RP107-1 RP107-1 LPV 102   T12S, K14R, I15V, L19T, K20R, E35D, R41K, L63P, H69K, V77I, V82I, L89M, I93L  
RP108 RP108 LPV, RTV 114 I54IV  L10I, I15V, L19I, K20R, E35D, M36I, R41K, I62IV, L63V, G68E, H69K, T74S, L89M  
RP112-3 RP112-3 RTV, LPV 260 I54IV, V82VA L10LF T12S, K14R, I15V, L19I, K20R, E35D, M36L, R41K, Q61H, L63P, H69K, V77I, L89M, I93L  
RP116 RP116 RTV 22   T12S, I15V, L19I, M36ML, N37AS, R41K, D60DE, L63LP, H69K, V77I, L89M, I93L P39P*QS 
RP117 RP117 LPV 182   T12S, I15V, L19T, M36I, R41K, L63T, E65D, H69K, L89M, I93L  
RP123-1 RP123-1 PI  M46I, I47V, I54V, L76V, V82A Q58E L10V, I15V, L19I, K20R, M36I, K55KR, D60E, L63P, H69K, A71V, L89M, I93L  
RP125 RP125 RTV, LPV 138 I54L V82~ L19I, K20R, E35D, M36I, R41K, L63A, H69K, K70Q, A71V, I93L  
RP126 RP126 RTV, LPV 348 M46I, I54V, L76V, V82L  Q7E, K14R, I15V, G16E, L19I, K20T, E35D, M36I, Q61N, L63C, H69K, L89I, I93L  
RP129 RP129 LPV 107   T12S, I15V, L19I, K20R, E35D, M36I, R41K, H69K, T74S, L89M, I93L  
RP130 RP130 RTV 60 V82A  T12S, I15V, L19I, N37A, R41K, L63P, H69K, L89M, I93L  
RP135 RP135 LPV 72   W6WR, T12S, I15V, L19I, M36I, N37S, R41K, H69K, L89M, I93L  
RP136 RP136 LPV, RTV 148 I54IV L33LF I15IV, Q18QP, L19M, E21EG, L24LF, T31TS, M36I, R41K, L63PT, H69K, T74TA, L89M, I93L K20KEGR, A22AGV, L23LF, T26TP, Q58QP 
RP138 RP138 LPV, RTV 231 M46I, I54V, L76V, V82A L10F I15V, L19V, K20R, E35D, M36I, R41K, K55R, R57K, D60E, I62V, H69K, A71V, L89M, I93L  
RP142 RP142 RTV, LPV 95 V82A  T12S, L19I, K20R, M36I, R41K, L63P, H69K, K70KQ, A71T, I93L A28AS 
RP144 RP144 LPV 143   Q7R, I15V, G16A, L19I, K20R, M36I, R41N, Q61H, H69K, V77I, L89M, I93L  
RP145 RP145 PI  M46I, I54V, V82A L10F, L24I, L33F, Q58E I15V, G17D, L19V, K20R, E35D, M36I, R41K, D60E, I62V, L63P, H69K, T91TN, I93L P81PS 
RP152 RP152 LPV 80   L5LF, T12S, K14R, I15V, L19V, K20R, E35N, M36I, N37D, R41K, L63V, H69K, L89M L23LF 
RP154 RP154 LPV, RTV 228 M46I, I54V, V82A Q58E L10I, T12S, I15V, L19I, K20R, E35D, M36I, R41K, K55KR, L63LP, H69K, K70R, L89IM, I93L  
RP156 RP156 LPV 122 M46L, I54V, V82A L10F T12S, I15V, L19I, K20R, E35D, M36I, R41K, I62V, L63V, H69K, T74A, L89M, I93L  
RP159 RP159 LPV 200 M46L, I54V, V82A L10F, L24I, L33F, T74AP I13IV, M36L, N37S, R41K, Q61N, I62V, L63V, H69K, L89M, I93IL  
RP167 RP167 LPV, RTV 312 M46I, I54V, V82A L10F, L24I, K43T I15V, L19I, K20R, E35D, M36V, N37E, R57K, I62V, L63P, H69K, V77I, L89I, I93L  
RP169 RP169 LPV, RTV 286 I54V, L76V, V82A  E35D, M36I, N37ND, R41K, R57K, L63P, H69K, A71V, T74S, L89IM, T91TI, I93L  
RP174 RP174 RTV, LPV 385 M46I, I54V, V82A L10F T12P, I15V, L19LI, K20KR, E35ED, M36MI, N37NS, R41K, L63A, H69K, A71AV, T91TI, I93LV  
RP176 RP176 LPV 210 V32VI, M46I, I54V, V82A L10F, L24I, L33LF, Q58E T4TN, L5LF, V11VF, I15V, L19I, K20T, E21EK, M36I, R41K, K55R, I62MV, L63P, H69K, A71V, I93L L23LF, T26TP, Q92Q* 
RP177 RP177 LPV 91   I13V, G16E, L19T, K20R, M36I, N37Q, P39S, H69K, T74S, L89M, I93L