<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author DeJesus (2012)
Title Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3, non-inferiority trial.
Citation Lancet
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 57
NumPts 35
Subtype B

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
7009 7009_1 None    E11D, E13ED, G70GE, L101I, S119R, T122TI, T124TN, R187RK, K188KR, G193E, V201I S283SG 
  7009_2 Unknown    E11D, E13ED, S39SN, D41DN, G70GE, L101I, S119R, R187RK, K188KR, G193E, V201I, T218TS S283SG 
7010 7010_2 Unknown    S39C, D41DN, M50I, L101I, T124A, T125A, V201VI, D253E S283G, R284G 
7016 7016_2 Unknown    E10D, K14KR, L101I, S119G, T122I, T124A, V201I, I220L  
7021 7021_1 None    D6E, E10D, E11D, K14R, V31I, M50T, I60L, K111Q, T124A, T206S  
  7021_2 Unknown    D6E, E10D, E11D, K14R, V31I, M50T, I60L, K111Q, T112TI, T124A, T206S  
7032 7032_1 None    S17C, A23AT, M50I, L101I, T112R, T124A, T125A, E157Q, K160Q, K219N, N222K, S230SN  
  7032_2 Unknown    S17C, A23AT, M50I, L101I, T112R, T124A, T125A, E157Q, K160Q, K219N, N222K, S230N  
7108 7108_2 Unknown    K14R, C56S, L101I, V201I, I208IL, I220L, Y227F, D256E V31VA, V281VA 
7113 7113_1 None    E11D, K14R, A21AT, T112V, T125A, G163T, D232DE, L234LF S230SDGN 
  7113_2 Unknown    E11D, K14R, A21T, T112V, T125A, F139FL, G163T, S230G, D232E, L234F  
7130 7130_1 None    S17N, L28I, S39SC, T124A, T125A, G163E, V201I, K240R  
  7130_2 Unknown    S17N, L28I, S39C, L45LI, T124A, T125A, G163E, V201I, K240R E212ED 
7149 7149_2 Unknown    L101I, T124TA, T125A, I135V, F181L, K188R, G193R, V201I, T206S, T218I, A265V V281M 
7154 7154_2 Unknown   T66TP K7KE, I84IM, S119T, M154L, V201I, T218S K160KI 
7173 7173_2 Unknown    E10A, E11D, S17N, V32I, K42R, I84L, L101I, S119P, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, D256E S283G 
  7173_3 Unknown    E10A, E11D, S17N, V32I, K42R, I84L, L101I, S119P, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, D256E S283G 
7177 7177_1 None   T97TA S24G, S39C, V79A, L101I, T124N, V201I, Q216R, K219Q, A265V S283G 
  7177_2 Unknown    S24G, S39C, V79A, L101I, T124N, V201I, Q216R, K219Q, A265V S283G 
7203 7203_2 Unknown    E11D, S17T, M50V, L101I, T112I, S119P, T124N, I135V, F181L, V201I, T206S, L242LF, A265V  
  7203_3 Unknown    E11D, S17T, M50V, L101I, T112I, S119P, T124N, I135V, F181L, V201I, T206S, A265V  
7207 7207_2 Unknown    E10ED, A23V, N27D, M50I, A91T, Q95P, L101I, T112A, S119R, T125P, V201I, T206S L241LF 
7264 7264_2 Unknown    R20K, L45I, K156N, S230SN, L234LH  
7266 7266_2 Unknown    E11D, D25E, V31I, M50I, M154L, V201I  
7299 7299_1 None    S17N, K34R, G59GE, I72IV, T112TI, I113IV, S119P, T124N, T125A, K136KT, V201I, S230N, D256E, Q274QK, D278DA S283SG, R284RG 
  7299_2 EVG 32 G140C, Q148R  K14R, S17N, K34R, G59E, S119P, T124N, T125A, H183HP, V201I, S230N, D256E  
7301 7301_2 Unknown    S39SC, L45LI, L101I, V201I, K219Q, D256E D286DN 
7304 7304_2 Unknown    E11D, S24N, N27S, A91T, E96D, L101I, S119R, T124S, T125A, I135IV, K156N, V165I, V201I, I208L, T210S, K211T, E212A, M275V S283G 
7325 7325_1 None    S17N, S39C, L101I, T112V, T124A, V201I, T218S, I268L  
  7325_2 Unknown    S17N, S39C, L45LI, L101I, T112V, T124A, V201I, T218S, I268L P261PS 
7330 7330_1 None    S119R, T125S, G193E, L234I, N254S, S255G, D279G  
  7330_2 Unknown    S119R, T125S, G193E, L234I, N254S, S255G, D279G  
7332 7332_2 Unknown   V54I S17N, V31VI, L101I, T124A, T125A, I208L, K215N, L234I, N254K, S255SG, A265V  
7359 7359_1 None    E10D, I72IV, L101I, S119P, T122I, T124N, T125S, T218S  
  7359_2 EVG 20 Q148R  E10D, I72IV, L101I, S119P, T122I, T124N, T125S, V165VI, T218S  
7413 7413_1 None    S17N, V31I, V32I, S39C, L101I, T112I, T124N, V201I, A205S, T206S, K211R, S230N  
7425 7425_1 None    S17N, V31VIM, I72IT, I84IL, V88VL, T124S, T125TA, K156N, I203M, D256E  
  7425_2 EVG 71 E92Q  S17N, I84L, V88VL, T124S, K156N, I203M, D256E  
7456 7456_1 None    D6E, E10D, M22MI, A23AV, T124N, V201I, D232E, D253DE, D256E  
7461 7461_2 Unknown    V31I, M50I, T124A, K188KR, T206S, Y227F, A265V  
  7461_3 Unknown    V31I, M50I, T124A, K188KR, T206S, Y227F, A265V  
7476 7476_1 None    K14R, S24N, L101V, K111R, T112V, T124A, V126M, K160Q, D167DE, V201I, K211R, S230N  
  7476_2 EVG 16 T66TI, E92EQ, N155NH  K14R, S24N, L101V, K111R, T112V, T124A, V126M, E157EQ, K160Q, D167E, V201I, K211R, S230N C65CG 
  7476_3 EVG 20 T66TI, E92EQ, N155NH  K14R, S24N, L101V, K111R, T112V, T124A, V126M, E157EQ, K160Q, D167E, V201I, K211R, S230N C65CG, G70GR 
7544 7544_1 None    S17N, V31VI, M50MI, L101I, T112TI, T124NS, T125V, G163E  
  7544_2 Unknown    S17N, V31I, V79VA, L101I, T112TI, T124NS, T125V, G163GE, A265AV  
  7544_3 Unknown    S17N, V31I, M50MI, L101I, T112TI, T124NS, T125V, G163E  
  7544_4 Unknown    S17SN, V31I, M50MIT, L101I, T112TI, T124NS, T125IV, G163E  
7562 7562_1 None    E11D, S24SN, D25E, L101LI, S119P, T122TI, K136N  
  7562_2 EVG 25 N155H  E11D, S24SN, D25E, L101I, S119P, T122I, K136N, D279DN  
7611 7611_1 None    K14KR, V31I, D41G, K42Q, L45Q, I84IM, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, L234I, D278A S283G, R284G 
  7611_2 Unknown    K14KR, V31I, D41G, K42Q, L45Q, I72IV, I84IM, P90PS, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, L234I, D278A S283G, R284G 
  7611_3 Unknown    K14R, V31I, D41G, K42Q, L45Q, I72IV, I84IM, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, L234I, D278A S283G, R284G 
7666 7666_2 Unknown   L74LIM E11D, L101I, K111KT, I113IV, S119AG, T122TI, T124N, S195T, V201I, T206S, Y227F, L234I, S255N, D256E H12HR, A86AV, T93TI, S283G 
7679 7679_2 Unknown    D25DE, V31VI, L74I, G163E, H171Q  
7706 7706_2 Unknown    A23AV, K156N, R187RK, K188R, V201I, S230SN, D256E L101LF 
7709 7709_1 None    D6E, E10D, E13ED, S17SN, V31VI, S57SN, G106A, T112TI, S119P, T122I, T124N, V201I, T206S, I208L, K211R, D256E