<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Sax (2012)
Title Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus co-formulated efavirenz, emtricitabine, and tenofovir for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3 trial, analysis of results after 48 weeks.
Citation Lancet
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 81
NumPts 44
Subtype B

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
6012 6012_1 None    E11D, K14R, S17T, S39SC, I60V, T112TI, I113IVL, T124A, T206S, E212A, N254NS S283SG, R284RG 
  6012_2 EVG 42 E92Q H51HY, L68V E11D, K14R, S17T, S39C, I60V, T112I, T124A, T206S, E212A  
6034 6034_2 Unknown    S17C, T112R, T125A, K188R, T218I, A265V  
  6034_3 Unknown    S17C, T112RS, T125A, K188R, K211KR, T218I, N222NK, A265V, R269RK  
6041 6041_1 None    K14KR, S17N, S24D, D25E, L28LI, S39C, G59GE, L101I, T124N, T125TA, V165I, L234LI D286N 
  6041_2 EVG 40 T66TI, E92EQ  D6DN, K14KR, S17N, S24D, D25E, L28LI, S39C, S57SG, L101I, T124N, V165I D286N 
6066 6066_2 Unknown    S17N, V31I, L101I, T124N, I135V, G163E, K173R, V201I, A205S, S230N  
6071 6071_1 None    K14R, V31I, S39C, L45Q, I84IM, K111T, V201I, K211KR, S230N, L234I, N254ND, D256E I251IT, D253DAE 
  6071_2 Unknown    K14R, V31I, S39C, L45Q, K111T, V201I, S230N, L234I, N254ND, D256E D253DAE 
6091 6091_2 Unknown    R20K, L101I, K111T, T122I, T124A, V201I R284RG, D286N 
  6091_3 Unknown    E11ED, R20K, L101I, K111T, T122I, T124A, V201I, R269RG R262RG, R263RG, R284G, D286N 
  6091_4 Unknown    E11ED, R20K, H51HR, L101I, K111T, T122I, T124A, Q164QK, V201I R284G, D286N 
  6091_5 Unknown    R20K, L101I, K111T, T122I, T124A, V201I R284G, D286N 
6101 6101_1 None    K7KR, E11D, K14R, A21T, A23V, D25DE, I72IV, L101I, K103KR, S119T  
  6101_2 EVG 32 E92EQ, Q148QR, N155NH  E11D, K14R, A21T, A23V, L101I, S119T  
6182 6182_1 None    M50MI, L101I, T112V, I220V, D253E  
  6182_2 EVG 25 E92Q  L101I, T112V, T210TI, I220V, L242LF, D253E R284G 
6214 6214_2 Unknown    E11D, M50MI, V88I, K111T, T112TI, S119P, T122TI, T125TA, V201I, T210TI, L234LF, L242LF  
  6214_3 Unknown    E11D, M50MI, V88I, K111T, S119P, T125TA, V201I  
6256 6256_2 Unknown    D6E, K14KR, A23AV, S24SG, P30PA, S39SC, I72IV, L74I, T124A, V201I, T206S, I208L, E212A, K215N S283G 
6257 6257_1 None    E11D, S17T, A23V, I72IV, T124A, G193E, V201I, I208M, E212SY, Q216H, I220L  
  6257_2 EVG 34 E92Q  E11D, S17T, A23V, I73V, T124A, S153A, G189GR, G193E, V201I, I208M, E212Y, Q216H, I220L  
6286 6286_1 None    S17N, M50I, L101I, T124A, G163E, G193E, V201I, D279N  
  6286_2 Unknown    S17N, M50I, L101I, T124A, G163E, G193E, V201I, D279N D286DN 
6290 6290_1 None    S17N, I84IV, E87ED, L101I, K156N, D256E  
  6290_2 Unknown    S17N, E87ED, L101I, K156N, D256E D286DN 
6306 6306_1 None    T124A, T210I, K211R, A265V, D279G  
  6306_2 Unknown    T124A, T210I, K211R, L234LF, A265V, D279G  
6332 6332_1 None    V31I, D55DN, I72IV, L101I, K103R, T112I, T124A, T125A, V126VI, V201I, A205T, K211R, I220L, Y227F, D253Y, A265V R284G 
  6332_2 Unknown    V31I, L101I, K103R, T112I, T124A, T125A, V201I, A205T, K211R, I220L, Y227F, D253Y, A265V E35EK, G47GE, Y83YC, E87EK, R284G 
  6332_3 Unknown    V31I, L101I, K103R, T112I, T124A, T125A, V201I, A205T, K211R, I220L, Y227F, D253Y, A265V R284G 
6334 6334_1 None    S17N, L28I, L45I, L101I, S119G, T122I, T124A, T125A, G163E, T218S  
  6334_2 Unknown    S17N, L28I, L45I, L101I, S119G, T122I, T124A, T125A, G163E, T218S  
6372 6372_2 Unknown    D6E, P30S, S39C, K111KR, V201I, T206S, S230H, D253DE S283SG 
6376 6376_1 None    V31I, M50I, L63I, L74V, E96D, L101I, T124N, T125A, G193E, V201I, I208IL, K211KR, E212X, T218S, S230N, D232E, D256E  
  6376_2 Unknown    V31I, M50I, L63I, L74V, E96D, L101I, T124N, T125AV, G193E, V201I, I208IL, K211KR, E212X, T218S, S230N, D232E, D256E  
6388 6388_1 None   T97A E11D, V31I, M50MT, G70E, L101I, T112I, S119R, T124N, D167E, V201I, T206S, I208L, E212A, T218S, K240KR, S255N, D256E R284G 
  6388_2 Unknown   T97A E11D, V31I, M50T, G70E, L101I, T112I, S119R, T124N, D167E, V201I, T206S, I208L, K211KN, E212A, T218S, S255N, D256E R284G 
6404 6404_2 Unknown    E11D, F26Y, L28I, V37I, S39C, M50I, G106A, T112R, T125A, V126L, V201I, T206S, K211R, K219N, N222K, S255N, I268L, M275V V281M, S283G 
6419 6419_2 Unknown    S17N, R20RK, V31I, T124A, E157Q, K160Q, V201I, K211R, N222K, S230SN, S255G, A265V L213S, R284G 
6428 6428_2 Unknown    E11D, S39C, L45Q, V201I, T218S  
6449 6449_1 None    S17C, G163E, K188R, K211R, Q216N  
  6449_2 Unknown    S17C, T124TA, G163E, K188R, K211R, Q216N, S230SN A21AV, G70GR 
6451 6451_2 Unknown   V151I K7R, S17N, L28I, Y227F, D253Y, D256E R284G 
6458 6458_1 None    M50I, K156N, V201I  
  6458_2 Unknown    M50I, K156N, V201I  
6469 6469_1 None    D6E, D25E, L101I, T112V, K156N, E157Q, K215N, D232E, L234H, D253E, D256E, D270N V110T 
6484 6484_2 Unknown    V31I, S39C, P90PS, E96EG, T124N, V201I, K215Q, T218S, S230N, D232E, L234H, D253E, N254D, C280CR  
6497 6497_1 None    S24T, V31VI, L101I, K111T, T112A, T124A, T125TA, I135V, I162IV, F181L, E212S, K215N, Q216H, T218S, S230N  
  6497_2 Unknown    S24T, L101I, K111T, T112A, T124A, I135V, I162V, F181L, E212S, K215N, Q216H, T218S, S230N K266KR 
6500 6500_1 None    S17N, L101I, T112I, T124N, G163E, V201I, A205S, T206S, D256E  
6503 6503_2 Unknown    E11D, K14R, S24N, D25E, M50I, T124A, T125A, I220L, I268L  
6518 6518_1 None    E13ED, S17C, T124N, T125A, I182V, K219N, N222K D288N 
6532 6532_1 None    S17N, L45V, I73V, P90S, L101I, T124N, G163H, I208L, I220L, D256E S283G 
  6532_2 Unknown    S17N, L45V, I73V, P90S, L101I, T124N, G163H, I208L, I220L, D256E S283G 
6534 6534_2 Unknown    K14R, K34R, V201I, T206S, N254Q, S255G, I267IV, M275MV  
  6534_3 Unknown    K14R, K34R, T112TI, V201I, T206S, N254Q, S255G, I267IV, M275MV  
  6534_4 Unknown    K14R, K34R, T112TI, V201I, T206S, N254Q, S255G, I267IV, M275MV  
  6534_5 Unknown    K14R, K34R, V201I, T206S, N254Q, S255G, I267IV, M275MV  
6545 6545_1 None    E11D, M50I, S119P, T122I, S195T, V201I, T218I, A265V  
  6545_2 EVG 97 N155H  E11D, M50I, S119P, T122I, S195T, V201I, T218I  
6556 6556_1 None    E10D, K34R, I72IV, L101I, K111R, T112TI, T124N, T125A, A175T, V201I, K211R, S230N S283G 
  6556_2 Unknown    E10D, K34R, I72IV, L101I, K111R, T112TI, T124N, T125A, A175T, V201I, K211R, S230N S283G 
6619 6619_1 None    E11D, S119P, T122TI, K219T, I220L, D232E, L234F  
  6619_2 Unknown    E11D, S119P, T122I, K219NT, I220L, D232E, L234F  
  6619_3 Unknown    E11D, S119P, T122I, K219T, I220L, D232E, L234F G47GR, E48EK, A86AT 
6628 6628_1 None    D6E, S17N, A98G, L101I, T124N, K136N, F181L, V201I, A265V  
  6628_2 Unknown    D6E, S17N, V79VA, A98G, L101I, T124N, K136N, G163GS, F181L, E198ED, V201I, A265V  
6630 6630_2 Unknown    S24SG, C56Y, S57N, K156N, K211R, L234I  
  6630_3 Unknown    E10EDG, E11ED, S24SG, C56Y, S57N, S119SGR, T122TI, K156N, K211R, L234I  
6648 6648_1 None    K14R, R20K, S24N, D25E, V31I, G59E, I60V, L101I, T124A, T125TA, V165VI, K215KR, N222K  
  6648_2 EVG 16 E92Q  K14R, R20K, S24N, D25E, V31I, G59E, I60V, L101I, T124A, T125A, D167DE, K215R, N222K  
6665 6665_2 Unknown   E138ED K7R, E11D, D25E, V31I, M50MT, I72IV, L101I, K111AT, S119SG, T122TI, T124TN, K188KR, V201I, Q216H, A265AV  
6667 6667_1 None    M50MI, T125A, I135V, M154MI, I162IV, V201I, K215N, L234I  
  6667_2 EVG 48 E92Q  M50I, T125A, I135V, M154I, I162V, V201I, K215N, L234I  
6668 6668_2 Unknown    K156N, I161L, V201I, T218S, Q221E, N222K  
6685 6685_1 None   A128AT E11D, A21T, L101LI, K111Q, T112A, S119SG, T122TI, T125TA  
  6685_2 Unknown   A128AT E11D, A21T, L101LI, K111Q, T112A, S119G, T122TI, T125A  
  6685_3 Unknown   A128AT E11D, A21T, L101LI, K111Q, T112A, S119SG, T122TI, T125A  
  6685_4 Unknown    E11D, A21T, M50MI, L101I, K111Q, T112A, S119SG, T122TI, T125TA  
6692 6692_2 Unknown    E11D, A21S, A23V, S24G, V37I, S39C, I60V, L101I, K219N, N222K