<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Stekler (2014)
Title Lack of resistance to integrase inhibitors among antiretroviral-naive subjects with primary HIV-1 infection, 2007-2013.
Citation Antivir Ther
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 69
NumPts 69
Subtype B, C

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
ACTU9148PHI50 ACTU9148PHI50 None    S17N, L101I, K111A, T124A, T125A, I135V, K156N, G163A, T218S  
ACTU9150PGA53 ACTU9150PGA53 None    E11D, A23V, T112V, V201I, K215S, S230N S283G 
ACTU9170PHI53 ACTU9170PHI53 None    E11D, S24N, D25E, V31I, S119G, T122I, T125A, K156N, V201I, A205S  
ACTU9176PHI55 ACTU9176PHI55 None    E11D, V31I, V32I, V37I, I72T, L74I, S119P, T124A, T125A, K136N, D167E, V201I, T218I, L234I  
ACTU9182PHI54 ACTU9182PHI54 None    E11D, V31I, V32I, V37I, I72AT, L74I, S119P, T124A, T125A, K136N, D167E, V201I, T218I, L234I  
ACTU9195PHI56 ACTU9195PHI56 None    E10D, S39C, L45V, M50I, I72V, I113V, D253E  
ACTU9201PHI57 ACTU9201PHI57 None    E11D, A21T, A38N, S39C, L45Q, I72V, L101I, T125V, I182V, V201I, D207N, K211T  
PIC1288PGX58 PIC1288PGX58 None    E11D, S24N, D25E, V31I, S119G, T122I, T124N, K188R, I200M, V201I, A265V  
PIC1777PFD49 PIC1777PFD49 None    E11D, D25E, L28I, S39C, I60V, Y99F, L101I, K111T, T112V, I113V, T124N, T125V, I135V  
PIC1778PFD50 PIC1778PFD50 None    V31I, L45Q, I72T, T112V, S119P, T122I, T124N, V201I, D256E  
PIC1779PFD51 PIC1779PFD51 None    S17N, L28I, S39C, I72V, K111T, T112TA, S119P, T122I, T124A, T125A, V201I, Q216R, K219N  
PIC1781PFD52 PIC1781PFD52 None    E11D, E13ED, V31I, A91T, L101I, S119P, T122I, T124A, K211Q  
PIC1784PFD53 PIC1784PFD53 None    S17N, V31I, I72V, L101I, I113L, T124N, H171Q, I182V, V201I, D256E S283G 
PIC1789PFQ49 PIC1789PFQ49 None    D6E, E10D, S39C, I72V, L101I, S119G, T122I, T124A, T125V, Q216H, T218S R284G 
PIC1790PFQ52 PIC1790PFQ52 None    D6E, E10D, S39C, I72V, L101I, S119G, T122I, T124A, T125V, Q216H, T218S R284G 
PIC1791PFQ51 PIC1791PFQ51 None    E11D, S17T, V32I, M50I, I72V, L101I, T112A, S119G, T122I, T125S, I182V, I203M, D256E  
PIC1792PFD54 PIC1792PFD54 None    R20K, L101I, T112V, S119P, T125V, G163E, L234I  
PIC1793PFQ53 PIC1793PFQ53 None    E11D, A38N, S39C, L45Q, I72V, S119G, T125V, I182V, V201I, D207N, K211T  
PIC1795PFW49 PIC1795PFW49 None    I72V, K111T, T112A, S119T, T125V S283G 
PIC1796PFD56 PIC1796PFD56 None    S17N, V31I, I72V, T124N, T125A, V126L, D256E  
PIC1803PFW50 PIC1803PFW50 None    K160KQ, S195T, V201I, D279DG S283SG 
PIC1804PFW51 PIC1804PFW51 None    L101I, S119P, T125A, I135V, V201I, S230N, D232E, D256E R284G 
PIC1806PFD59 PIC1806PFD59 None    D6E, E10D, I72V, L101I, S119P, T122I, T124A, G163E, I182V, V201I  
PIC1808PHM59 PIC1808PHM59 None    G59E, L101I, T112A, S119P, T206S, I208L, E212A, S230N, R231K  
PIC1810PFQ50 PIC1810PFQ50 None    E11D, K14R, S39C, I72V, L74I, L101I, S119P, V176T, S195T, V201I, I203IM, S230N  
PIC1812PGA49 PIC1812PGA49 None    E11D, V31I, K111T, T122I, T125V, I208L, K211R  
PIC1814PGX50 PIC1814PGX50 None    D6E, S17N, V32I, G70E, Q95R, T124N, T125A, V126L, T206S, D253E, D256E L101LF 
PIC1815PFQ54 PIC1815PFQ54 None    A38N, S39C, L45Q, E48EG, I72V, T124A, T125A, V201I, D207N, K211T, Q221R  
PIC1817PHM52 PIC1817PHM52 None    L45V, M50T, L101I, T112V, T124N, K136Q, V201I, T218I, L234I, I251L, A265V, R269K, D278A V281M 
PIC1818PGK49 PIC1818PGK49 None    E11D, S24N, K34R, M50I, I72IV, L101I, I135IV, K160KN, K211R  
PIC1819PFW52 PIC1819PFW52 None    L45V, K111T, T112A, S119T, T125A, I220V  
PIC1821PGK50 PIC1821PGK50 None    D6E, A23V, S24G, L101I, V110I, T206S, A265V  
PIC1822PFN50 PIC1822PFN50 None    S17N, I72V, I113V, T124S, T125A, K211Q, S230N  
PIC1825PHM54 PIC1825PHM54 None    L101I, K111A, T124A, T125A, I135V, K156N, G163A, T218S  
PIC1834PHI51 PIC1834PHI51 None    A38N, S39C, L45Q, I72V, T124A, T125A, I182V, V201I, D207N, K211T  
PIC1835PHI52 PIC1835PHI52 None    E11D, V31I, V32I, V37I, I72T, L74I, S119P, T124A, T125A, K136N, D167E, V201I, T218I, L234I  
PIC1836PGX49 PIC1836PGX49 None    A38N, S39C, L45Q, I72V, T124A, T125A, I182V, V201I, D207N, K211T  
PIC1844PGK52 PIC1844PGK52 None    E11D, L101I, K111T, S119T, V201I, V260I  
PIC1850PHD50 PIC1850PHD50 None    E11D, V31I, V32I, V37I, I72T, L74I, T124A, T125A, K136N, D167E, V201I, T218I, L234I  
PIC1856PGK53 PIC1856PGK53 None    E11D, V31I, K111T, S119G, T125V, I208L  
PIC1857PGK54 PIC1857PGK54 None    E11D, K14R, S17T, A23V, L101I, S119A, T122I, T124A, K156N, V201I  
PIC1858PFY49 PIC1858PFY49 None    E10D, S39C, L45V, M50I, I72V, I113V, D253E  
PIC1861PGK55 PIC1861PGK55 None    E10D, S39C, L45V, M50I, I72V, I113V, D253E  
PIC1865PHM55 PIC1865PHM55 None    L101I, I113V, T124N, K240R  
PIC1868PFN51 PIC1868PFN51 None    D6E, E11D, E13D, S24N, E96D, L101I, S119R, T122I, T124S, T125A, I182V, T206S  
PIC1869PHM53 PIC1869PHM53 None    L101I, K156N, K173R, I208L, L234I S283G 
PIC1872PHM49 PIC1872PHM49 None    L101I, I113V, T124N, K240R  
PIC1875PGK57 PIC1875PGK57 None    E11D, V31I, L45Q, S57N, L101I, S119G, T122I, T124N, T125S, G163E, K173R, A205T  
PIC1876PFW53 PIC1876PFW53 None    L45Q, M154I, S195T, V201I, L234V  
PIC1878PGK58 PIC1878PGK58 None    E11D, S24N, D25E, V31I, M50I, V77I, I84M, K111Q, T112A, T125A, G163Q, L234I, D253E, D278N  
PIC1884PGX51 PIC1884PGX51 None    S39C, L74I, T124A, V201I I161ILM 
PIC1884PHD51 PIC1884PHD51 None    S39C, L74I, T124A, G163GA, V201I I161ILM 
PIC1888PFY51 PIC1888PFY51 None   L74M E11D, E13D, V37I, I72V, S119P, T122I, K173R, V201I, T206S, N222H, D256E  
PIC1889PGA52 PIC1889PGA52 None    E10D, V31I, I72V, I84M, T124N, M154L, V201I, N222K D167DY 
PIC1890PFW54 PIC1890PFW54 None   E138D K71Q, L101I, S119P, T122I, T124N, I208L, K211T, E212A, S230N, A265V S283G 
PIC1892PHM56 PIC1892PHM56 None    L101V, K111T, T122I, T124A, T125A, I208L  
PIC1893PFY52 PIC1893PFY52 None    E10D, L101I, S119P, T125A, I135V, S195N, V201I, S230N, D232E, D256E, D278N V281M, R284G 
PIC1895PHM57 PIC1895PHM57 None    L45Q, M154I, S195T, V201I, L234V  
PIC1896PHM50 PIC1896PHM50 None    M50I, L101I, K111R, T112I, G163E, V201I, S230G  
PIC1897PGX53 PIC1897PGX53 None    M50V, I72V, T122I, T124N, T125A, V126L, M154L, K211R, A265V  
PIC1898PHM58 PIC1898PHM58 None   V54I M50I, L101I, T112A, S119SG, K156N, R187K S283G 
PIC1899PGX54 PIC1899PGX54 None    E11D, A21T, S39C, V201I, D270E S283G 
PIC1904PGX56 PIC1904PGX56 None    E11D, A21T, A38N, S39C, L45Q, I72V, T124A, T125V, I182V, V201I, D207N, K211T  
PIC1908PHM60 PIC1908PHM60 None   V151VI I72IV, L101I, T122TI, K156KN, K188KR, V201VI, D256DE  
PIC1909PHD53 PIC1909PHD53 None    A38N, S39C, L45Q, I72V, T112A, T124A, T125A, I182V, V201I, D207N, K211T  
PIC1910PGX57 PIC1910PGX57 None    A38N, S39C, L45Q, I72V, T124A, T125A, I182V, V201I, D207N, K211T  
PIC1912PGX59 PIC1912PGX59 None    A38N, S39C, L45Q, I72V, T112A, T124A, T125A, I182V, V201I, D207N, K211T  
PIC1916PHI49 PIC1916PHI49 None    E10D, M50T, L74I, A91E, K111T, S119R, T124N, V165I, V201I, E212A, K215Q, D279G R284G 
PIC1917PHM61 PIC1917PHM61 None    V201I, T206S