<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Kebe (2013)
Title High rate of antiretroviral drug resistance mutations in HIV type 1 infected Senegalese children in virological failure on first-line treatment according to the World Health Organization guidelines.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 52
NumPts 52
Subtype CRF02_AG, C, G, A, D, CRF06_cpx

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
SN1302HALD SN1302HALD NRTI NNRTI M41L, M184V, L210RW, T215Y K103N K22KR, V35T, T39A, E44ED, V60VI, S68G, V90I, I135V, I142IV, S162A, T165L, K173T, Q174E, D177E, I178M, T200A, Q207E, R211K, P243T, V245KQ, E248D, A272P, T286A, V292VI, I293V, P294T, H315Q, S322T, I326V  
SN1835HALD SN1835HALD NRTI NNRTI M41ML, M184V, L210LW, T215Y K103N K20R, V35T, E36D, T39LS, I135T, S162AT, K173I, Q174K, D177E, T200A, Q207E, R211RK, V245Q, T286A, A288AT, E291D, I293V, S322A  
SN1921HALD SN1921HALD NRTI EFV M184V Y188L K43Q, S68SG, V106I, D123E, I135T, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, V245K, D250E, A272P, K277R, T286A, E291D, V292I, I293V, S322T  
SN2200HALD SN2200HALD AZT, 3TC NVP M184V K103N, Y181C K20R, V35T, E36D, K122E, D123S, I142IV, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, P243S, V245K, E248D  
SN2512HALD SN2512HALD NRTI NVP M184V V106AP, E138K P4T, P14A, V35T, E36D, T39M, S48T, K122P, D123S, I135T, S162A, K173T, Q174K, D177E, T200A, Q207E, V245K, D250E K64KT, T84TP 
SN2710HALD SN2710HALD NRTI NVP  K103KN V35I, I135M, S162A, K173T, Q174K, D177E, T200A, I202IV, Q207E, V245E, E248Q, T286A, E291D, V292I, I293V, P294T, S322T, D324DE, I326V  
SN432HALD SN432HALD NRTI NVP  G190A V35T, E36D, T39K, K43E, I135L, E138G, S162A, K173T, Q174K, D177E, I178M, T200A, E203D, Q207E, V245Q Q222Q* 
SN626HALD SN626HALD NRTI NVP K70T Y181C V35T, E36D, K49R, V60I, K122E, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, F214L, H221Y, L228R, V245Q, E248D  
SNA3-025 SNA3-025 NRTI NVP M184V, T215Y Y181C K43KQ, K49R, D123DE, I135V, S162A, K173T, Q174K, N175Y, D177DE, T200A, Q207E, R211K, T240K, P243T, V245K, Y271F, R284K, T286A, E291D, V292I, I293V, P294T, E297K, S322T, I326V  
SNA3-045 SNA3-045 NRTI EFV M41L, D67N, L74V, M184V, L210W, T215Y, K219N K103N, V179F, Y181C, G190A V35T, E36D, V60I, K101R, V118I, I135T, K173T, Q174K, D177E, G196E, T200A, E203K, Q207E, R211K, K223Q, L228H  
SNA3-066 SNA3-066 NRTI EFV M184V Y188L V35T, V60I, A98S, V106VI, D121DE, K122E, I135L, K173L, Q174K, D177E, V179I, T200A, Q207E, R211K, F214FL, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, E297A, S322A, D324E, I329V  
SNA3-107 SNA3-107 NRTI NNRTI M184V K103N K20R, V35T, T39E, S48T, T69TP, K122E, I135M, K173T, Q174K, D177G, I178L, T200A, Q207E, R211K, F214L, V245Q, E248D, A272P D76DN, T84TP 
SNA3-125 SNA3-125 NRTI NNRTI M184V, T215Y K103N V35T, K122P, I135L, S162A, K173T, Q174E, D177E, G196E, T200A, Q207E, V245E, E248D, A272S  
SNA3-127 SNA3-127 AZT, 3TC NVP M41L, V75I, M184V, L210LW, T215F A98G, Y181C V35T, E36D, T39A, V60I, I132L, I135L, S162A, K173T, Q174K, D177E, T200A, Q207E, H221Y, V245K, K249Q, A272P, K275KR, R284K, T286A, E291D, V292I, I293V, P294A, S322T Y183Y* 
SNA3-133 SNA3-133 NRTI NVP M41L, T215Y K101E, Y181C, G190A V35T, E36D, K49R, T69N, V90I, L109I, K122E, I135V, T139K, S162A, E169D, K173A, Q174K, D177E, I178M, G196E, T200A, E203Q, Q207E, H208Y, R211K, L228R, V245E, E248D  
SNA3-139 SNA3-139 NRTI NVP M184V A98AG, K101E, V108I, G190A V35T, E36D, V60I, K102Q, V106I, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E  
SNA3-144 SNA3-144 AZT, 3TC NVP M184V K101KE, Y181C, G190A V35T, K49R, I50IF, V60I, V90I, D121H, K122E, I135T, S162H, T165I, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, F214L, V245T, D250E  
SNA3-157 SNA3-157 NRTI NVP T215TFIS Y181C K11T, V35T, K49R, E53D, V90I, D121H, K122E, I135T, S162H, K173T, Q174K, D177E, V179I, I195L, T200A, I202V, Q207A, R211K, V245VELQ, E248ED, D250DE, A272P, K275R, T286A, E291ED, I293V, P294V, E312N  
SNA3-159 SNA3-159 AZT, 3TC EFV M184V Y188L, P225H V35T, E36D, V60I, D123E, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, V245E  
SNA3-161 SNA3-161 NRTI NVP M41L, M184V, L210W, T215Y K103N V35T, E36D, K43E, K49R, V90I, V118I, K122E, D123E, I135V, S162A, E169K, K173T, Q174K, N175Y, D177E, T200A, Q207E, R211K, L228H  
SNA3-168 SNA3-168 NRTI NVP M184V K103N E6ED, T7TP, V35T, K49R, E53D, D123E, S162A, K173T, Q174K, D177E, G196E, T200A, Q207E, R211KT, F214L, V245E  
SNA3-175 SNA3-175 NRTI NVP M41L, T215Y K101E, Y181C, G190A V35T, E36D, K49R, T69N, V90I, L109I, K122E, I135V, T139K, S162A, E169D, K173A, Q174K, D177E, I178M, G196E, T200A, E203Q, Q207E, H208Y, R211K, L228R, V245E, E248D  
SNA3-185 SNA3-185 NRTI EFV M184V, T215F Y188L V35T, E36D, S68SG, L109LI, K122E, I135L, S162A, T165I, K173T, Q174K, D177E, G196E, T200A, I202V, Q207G, R211RS, V245Q, E248D  
SNA3-188 SNA3-188 NRTI NVP M41L, D67N, L74I, V75M, M184V, L210W, T215Y, K219N A98G, K101E, G190S K22R, V35T, T39A, E44D, V118I, K122E, D123N, S162T, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, A272P  
SNA3-191 SNA3-191 NRTI NVP M184V Y181C T7P, V35T, E36A, T39E, S48T, I135T, K173A, D177E, G196E, T200A, Q207E, V245K, A272P  
SNA3-195 SNA3-195 AZT, 3TC NVP M184V K101E, G190A V21I, V35T, T39A, V60I, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207R, R211E, V245Q, A272P, K275R, K281R, L283I, E291D, I293V, P294T, E297EK, S322T  
SNA3-196 SNA3-196 AZT, 3TC NVP M184V K101E, G190A V21I, V35T, T39A, V60I, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207R, R211E  
SNA3-214 SNA3-214 NRTI NNRTI A62V, K65R, V75I, F116Y, Q151M, M184V, K219E V108I, Y181C I31L, V35T, E36D, V60I, K64R, S68R, V118I, K122E, S162A, K173T, Q174K, D177E, T200A, Q207K, R211S, F214L, V245Q N81NT, R143R* 
SNA3-215 SNA3-215 AZT, 3TC NVP M184MV K103NS, G190A K11KR, T27TS, V35T, K64R, K122P, D123E, S162A, K173Q, Q174K, D177E, V179I, T200A, Q207E  
SNA3-220 SNA3-220 NRTI NVP T69D, M184V V108I, Y181C V35T, E36A, T39E, K49R, A98S, K101R, D123N, K166Q, R172K, Q174K, D177E, I178L, T200A, Q207E, R211K, H221Y, E224D, V245Q, D250E, A272P, K277R  
SNA3-228 SNA3-228 NRTI NNRTI   V35T, S162A, K173T, Q174K, T200A, Q207E  
SNA3-234 SNA3-234 NRTI NVP M184V A98G, V179E, Y181C V35T, V60I, K102N, I135V, S162A, K173T, Q174N, D177E, T200A, Q207E, V245Q  
SNA3-242 SNA3-242 AZT, 3TC NVP D67N, K70R, M184V, T215F, K219E K103N, Y181C, K238T V35T, E36D, T39A, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, V245Q, E248D, A272P  
SNA3-248 SNA3-248 AZT, 3TC NVP M184V, T215Y K103N V35T, E36D, T39L, S48T, V60I, V90I, I135T, A158S, S162A, T165L, K173T, Q174K, D177E, T200A, I202V, Q207E  
SNA3-250 SNA3-250 NRTI NVP M184V V106A, F227L V35T, K49R, S68G, V90I, K122E, D123E, I135V, S162A, K173T, Q174R, D177E, T200A, Q207E, R211K, F214L, V245Q, D250DE Q23QH 
SNA3-251 SNA3-251 NRTI NNRTI   V35T, T39L, K43R, K122E, D123N, S162C, F171Y, K173A, Q174K, D177E, I178L, Q207A, R211K E233EK 
SNA3-262 SNA3-262 NRTI NVP M184V K101E, G190A E28EK, V35T, E36D, K49R, V60I, V90I, K102Q, K122Q, I135V, S162A, E169N, K173A, Q174K, D177E, I178M, T200A, Q207E, R211K, V245E  
SNA3-268 SNA3-268 NRTI NVP M41L, M184V, L210W, T215Y Y181C K20R, K32I, V35K, T39A, I135V, K173T, Q174K, D177E, V179VI, T200A, Q207E, R211K, L228R  
SNA3-274 SNA3-274 NRTI NVP  K101KE V35T, E36A, T39K, K43E, V60I, K122E, D123N, I135T, E138A, I142V, S162A, K173V, Q174K, D177E, I178V, V179I, G196E, Q197QR, T200A, Q207D, R211K, F214L, V245Q, A272P, I274V, K275KR, Q278H, K281R, R284K, T286A, E291D, V292I, I293V, P294T, I326V  
SNA3-276 SNA3-276 NRTI EFV D67N, K70R, M184V, T215F, K219E Y188L V21I, V35T, T39S, V60I, K122E, D123S, S162A, K173T, Q174K, D177E, I178V, T200A, Q207E  
SNA3-278 SNA3-278 AZT, 3TC EFV M184V K103N, P225H V35T, T39L, S68G, K122E, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E  
SNA3-286 SNA3-286 NRTI EFV K70KR, M184V V179E, Y188L K20R, V35T, T39M, V60I, D123E, I135V, I142V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L S191SF 
SNA3-302 SNA3-302 NRTI NVP M184V K101E, G190A V35T, E36D, T39A, K49R, V60I, S68G, K122E, I135R, S162A, K173R, Q174K, D177E, I178M, T200A, Q207G, R211K, V245Q, E248D  
SNA3-310 SNA3-310 D4T, 3TC NVP M184V K103N, V106VA K20R, V21I, T27S, V35T, V60I, K64KN, S162A, K173A, Q174K, D177E, I178M, T200A, Q207E, V245E N81NK 
SNA3-324 SNA3-324 NRTI NVP  V106A V35T, V60I, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, F214L, P243A, V245Q, D250E  
SNA3-325 SNA3-325 NRTI NNRTI   V35T, E36D, I135V, S162A, K173I, Q174K, D177E, T200A, Q207E, R211K  
SNA3-329 SNA3-329 D4T, 3TC NVP M184V K103N I31L, V35T, T39A, V90I, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, V245T  
SNA3-340 SNA3-340 AZT, 3TC NNRTI M41ML, M184V, T215Y A98G, Y188YF E6K, V35T, K49R, V60I, S68G, V90I, K122E, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K G45A 
SNA3-345 SNA3-345 NRTI NNRTI   E6D, K11T, V35T, E36A, T39K, K43E, K122EV, D123N, I135V, S162A, K173T, Q174K, D177E, Q197QE, T200A, Q207E, R211K  
SNA3-349 SNA3-349 NRTI NVP M184I Y181V, L234LI V35T, E36D, I37IF, I47IF, V90I, K122E, D123N, I135V, S162A, T165I, K173T, Q174K, D177E, T200A, Q207E, R211K E233KN 
SNA3-364 SNA3-364 AZT, 3TC NVP M41ML, M184V, T215TFIS A98G, K101E, V108VI, Y181C S3SI, I5IM, V21VI, V35T, E36ED, I37IF, T39TA, K49R, V60I, D121DE, K122E, D123N, I135V, I142V, S162T, K173KT, D177E, I178M, Q207A, R211K, L228R P52PFLS, E169E* 
SNA3-391 SNA3-391 AZT, 3TC NVP  E138K, G190A V21I, V35T, E36D, T39M, K49R, V60I, V90I, K122E, S162A, K173T, Q174K, D177E, I178M, T200E, E204K, Q207E, R211K