<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Hoffmann (2013)
Title Resistance to tenofovir-based regimens during treatment failure of subtype C HIV-1 in South Africa.
Citation Antivir Ther
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 52
NumPts 52
Subtype C

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
032195_1 032195_1 TDF, 3TC EFV  V106VM, V179VD V35T, E36A, T39D, S48T, K82R, K122E, I142T, K173A, D177E, T200A, Q207DEKN, R211K, V245Q  
104350_2 104350_2 TDF, FTC EFV   V35T, T39E, V90I, K122E, D123S, S162C, K173A, D177E, T200A, Q207E, R211K, V245Q  
138524 138524 TDF, 3TC EFV K65R, M184V K103N, Y181C T27TS, V35T, E36A, T39E, S48T, K102KR, K122E, D123N, K173T, Q174K, D177E, T200A, Q207E, V245K  
158876_1 158876_1 TDF, FTC EFV M184V V108I, Y181C K20R, K22R, V35T, T39K, E40D, S48T, V60I, K122E, D123S, I135V, T139S, K173E, Q174K, D177E, T200A, Q207E, F214L, V245Q, D250E  
169054_1 169054_1 TDF, FTC EFV  K103N, P225H V35T, E36A, T39E, S48T, K122E, D123G, S162C, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D  
188445 188445 TDF, FTC EFV  K103KN V35T, E36A, T39E, S48T, K122E, D123DG, T165I, D177DN, I178IL, T200A, Q207EK, F214FL, V245Q, D250E  
194437_1 194437_1 TDF, FTC EFV   V35T, T39E, V90I, K122E, D123S, S162C, K173A, D177E, I178IM, T200A, Q207E, R211K, V245Q  
19605 19605 TDF, FTC EFV   V35T, T39E, E40D, K122E, D123S, I135T, E138A, T139V, S162W, K173A, D177E, V179I, T200A, Q207E, R211K, V245Q  
25933 25933 TDF, FTC EFV  K103N, Y181C K20R, K22R, V35T, T39K, E40D, S48T, V60I, K122E, D123S, I135V, T139S, E169EG, K173E, Q174K, D177E, T200A, Q207E, F214L, V245Q, D250E F124FV 
324161 324161 TDF, FTC EFV  K101E, V106M V35T, E36A, T39E, S48T, K122E, K173A, D177E, T200A, Q207N, V245Q, D250E  
324748 324748 TDF, 3TC NVP   V35T, E36A, T39E, S48T, V60I, K122E, D123S, K126KR, T165I, K173A, D177E, T200A, E203EK, Q207E, R211K, V245Q  
332493 332493 TDF, FTC EFV M184V K103N, G190A V35T, T39E, V90I, K102N, K122E, D123G, K173T, Q174R, D177E, T200A, Q207E, R211K, I244V, V245Q  
348779 348779 TDF, FTC EFV   P4PS, K20R, K32KQ, V35T, E36EA, T39E, S48T, V118VI, K122KE, D123DG, Q145E, T165I, K173T, Q174K, D177E, G196E, T200A, Q207A, R211K, F214L, V245Q, E248ED, S251SN  
366188_1 366188_1 TDF, 3TC NVP   E6ED, V35T, E36A, T39E, E40D, S48T, W88C, K122E, D123N, K173V, Q174K, D177G, I178L, T200A, Q207N, R211RK, V245Q  
366736_1 366736_1 TDF, 3TC EFV M184V  V35M, E36A, T39E, K46Q, S48T, K122E, D123N, K173V, Q174K, T200A, Q207K, R211K, V245Q, D250E  
385473 385473 TDF, 3TC NVP K65R, M184V Y181C V35T, E36A, T39E, S48T, E53D, K122E, A158T, K173A, Q174R, D177E, T200A, Q207E, R211K, P243T, V245Q  
399048_1 399048_1 TDF, 3TC NVP K65R, M184I K103N, M230L V35T, T39E, S48T, K122E, D123N, K173A, Q174K, D177E, Q197P, T200A, Q207E, V245Q, S251N  
404545 404545 TDF, FTC EFV  K103N V35T, E36A, T39E, S48T, K122E, D123S, A158S, K173A, Q174K, D177E, G196E, Q197H, T200A, Q207E, P243A, V245Q  
418251 418251 TDF, FTC NVP K65R, D67N, M184V G190A V35T, T39E, S48T, K102R, D121H, K122E, E138Q, S162C, K173T, D177E, I178L, T200A, Q207K, R211K, V245K  
418714 418714 TDF, 3TC None  K103KN V35T, T39E, K122E, D123DN, K173T, Q174K, Q197QE, T200A, Q207KR, R211RK, V245K  
423142 423142 TDF, 3TC NVP  K103KN V35T, E36A, T39E, S48T, V60VI, K122E, D123GS, I135V, K173A, Q174K, D177E, I178IM, Q197QK, T200AE, R211Q, P243AT, V245Q  
425256 425256 TDF, 3TC EFV   V35T, T39RS, S48T, K122E, D123G, T165I, K173A, Q174K, D177E, T200A, I202IV, Q207E, R211RK, V245Q  
426244 426244 TDF, 3TC NVP   V35T, E36EA, T39D, S48T, D86DE, D121Y, K122E, D123DN, R125RK, S162A, K173T, I178L, T200A, Q207K, R211Q, D250E  
442678 442678 TDF, FTC EFV  V106M, V179D V35T, T39E, S48T, K49KR, E53D, K122E, D123N, K173T, D177E, T200A, Q207E, F214L, L228Q, V245C  
449813_2 449813_2 TDF, 3TC EFV A62V, M184V V106M, V179D, F227L V35T, E36A, T39D, S48T, K82R, K122E, K173A, D177E, T200A, Q207E, R211K, F214L, V245Q M16I, E203T 
452356_2 452356_2 TDF, 3TC EFV K70Q, M184V Y181C, G190A V35M, E36A, T39E, K46Q, S48T, K122E, D123N, T139K, K173V, Q174K, T200A, Q207K, R211K, V245Q, D250E  
454522 454522 TDF, FTC EFV   V35T, E36A, T39E, S48T, V60I, A98S, D121Y, K122E, A158S, T165I, K173R, D177E, T200A, Q207K, R211Q, V245Q  
45711 45711 TDF, 3TC NVP   V35T, E36A, T39D, S48T, V60I, K103KR, K122E, K173A, Q174K, D177E, I178IM, T200A, E203ED, Q207AE, R211K, V245Q  
457521 457521 TDF, FTC EFV   V8I, G15GE, V35T, E36A, T39D, S48T, V60I, K104R, K122E, D123S, K173A, Q174K, D177E, I178M, T200A, Q207E, R211K, V245Q, D250E  
461994_2 461994_2 TDF, 3TC NVP K65R, M184I K103N, M230L V35T, T39E, S48T, K122E, D123N, K173A, Q174K, D177E, Q197P, T200A, Q207E, V245Q, S251N  
463056 463056 TDF, 3TC NVP   V35T, E36A, T39E, S48T, K122E, D123N, K173S, D177E, T200A, E204K, Q207E, K223R, V245L  
466725 466725 TDF, FTC EFV  K103N V35T, E36A, T39E, S48T, K122E, D123N, I135V, A158AS, S162C, K173A, D177E, T200A, E204K, Q207E, R211RM, V245E, E248D, S251I  
478443 478443 TDF, 3TC NVP K70R, M184V, K219Q K103N K20R, E28D, V35T, E36A, T39E, S48T, K82R, V90I, K122E, D123S, I135L, E138A, T139I, S162A, E169K, K173D, T200E, Q207E, R211K, F214L, L228R, V245Q  
479756 479756 TDF, 3TC EFV K65R K103N, V106M P4PH, V8I, V35T, T39K, S48T, F87FL, W88C, K122E, I142V, K173A, D177E, T200A, Q207E, R211K, F214FL, V245Q  
480206 480206 TDF, FTC EFV   V35K, T39E, S48T, E53ED, K122E, S162C, E169D, D177DE, T200A, Q207E, R211K, V245E  
491648_1 491648_1 TDF, FTC None  V106M, V179D V35T, T39E, S48T, K49KR, E53D, K102KR, K122E, D123N, K173T, D177E, T200A, Q207E, F214L, L228Q, V245C  
497644_2 497644_2 TDF, 3TC NVP K70KE, M184V A98G, V108VI, Y181C V35T, E36A, T39E, E40D, S48T, W88C, K101KRT, K122E, D123N, K173V, Q174K, D177G, I178L, T200A, E203Q, Q207D, R211K, H221HY, V245Q  
55883 55883 TDF, FTC EFV M184V K103N, V108I, P225H V35T, E36A, T39D, S48T, K82R, A98S, K122E, D123G, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, V245Q  
56524 56524 TDF, FTC EFV M184V K103N, V108VI, P225H V35T, E36A, T39E, E40D, S48T, V60VI, K122E, D123N, I135L, E138Q, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, D250E  
58155 58155 TDF, 3TC NVP   V35T, E36A, T39E, S48T, V60I, K104R, T139TI, I142IV, K173T, D177E, T200A, Q207AT, V245Q, D250E  
602661_3 602661_3 TDF, FTC EFV  K103N, Y181C K20R, K22R, V35T, T39K, E40D, S48T, V60I, K122E, D123S, I135V, T139S, K173E, Q174K, D177E, T200A, Q207E, F214L, V245Q, D250E  
603129 603129 TDF, FTC EFV  K103N P4PS, V35T, T39E, S48ST, V60VI, K102N, K122E, D123S, I135IT, S162Y, K173A, D177E, T200A, Q207A, R211K, F214L, V245Q  
603139 603139 TDF, FTC EFV  L100LI, K103N, V106VM K20R, V35I, T39E, S48T, W88C, V90VI, K122E, D123G, T165IV, E169EG, K173A, D177E, T200A, I202V, E204K, Q207E, R211K, F214FL, L228LR, V245Q  
604099 604099 TDF, FTC NVP M184V K103N, G190A P4S, E6D, V35T, T39E, S48T, K122E, D123G, T139A, K173T, Q174K, D177E, I178L, T200A, Q207E, V245Q  
605124 605124 TDF, FTC EFV   V35T, E36A, T39E, S48T, K104R, D121Y, K122E, K173A, Q174R, P176K, T200A, Q207E, R211Q, F214L, V245Q, E248ED  
605197 605197 TDF, FTC EFV   K32KR, V35T, T39E, S48T, K122E, K173I, D177DE, G196V, T200A, Q207E, R211K, V245K  
607720_1 607720_1 TDF, FTC NVP M41L, L210W, T215Y K103N, Y181C V35T, T39E, E44D, S48T, A98S, K122E, I135T, K173T, Q174K, D177E, T200A, Q207E, R211K, P225Y, L228Q, V245Q  
607996_2 607996_2 TDF, FTC EFV  K103N, P225H V35T, E36A, T39E, S48T, K122E, D123G, S162C, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248ED  
610004 610004 TDF, FTC EFV D67DN, M184V A98G, K103KN, F227FL V35T, T39E, S48T, K122E, D123S, I135T, S162C, K173A, D177E, T200A, E204KQ, Q207A, R211K, F214L, V245Q  
8302 8302 TDF, 3TC NVP   V35T, E36A, T39E, S48T, K122E, D123S, I159V, K173T, T200A, Q207E, V245Q  
90131 90131 TDF, FTC EFV   V35T, E36A, T39E, S48ST, V60I, K102KQ, K122E, D123G, E138EA, I142IMT, K173A, Q174QK, D177E, I178L, T200A, Q207D, R211K, V245Q  
94344 94344 TDF, 3TC EFV  V106M V35T, T39E, S48T, K122E, D123N, K173T, D177E, T200A, Q207A, R211K, V245Q