<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Niama (2006)
Title HIV-1 subtypes and recombinants in the Republic of Congo.
Citation Infect Genet Evol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 50
NumPts 50
Subtype G, A, D, CRF45_cpx, H, CRF02_AG, J, F, G + J, CRF05_DF, CRF18_cpx, G + Unknown, A + G

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
ARV04 ARV04 None None   V35T, K49R, I50V, K101R, K122E, I135S, I142V, K173T, Q174K, D177G, T200E, I202V, Q207E, R211K, V245Q, E248D, D250E, Q278N, T286A, E291D, V292I, I293V, P294T, E297A, F346H, M357T, G359S, V365I, A376S, T377M, K390R, A400T, T403I  
ARV26 ARV26 None None   K11T, V35T, T39D, D121H, K122E, D123S, I135T, K173S, Q174K, D177E, I178L, G196K, T200I, Q207V, R211N, V245Q, E248D, D250E, S251H, A272P, K275R, Q278H, K281R, T286A, E291D, V292I, I293V, P294T, A304E, G335D, M357K, R358K, G359A, T362TS, K366R, E370D, A371M, T377M, K385R, T386V, K390R, K395R, A400T  
ARV32 ARV32 None None   P4T, E6D, V35T, V60I, W88C, T107S, V118I, D121C, K122E, I135V, I142V, S162A, D177E, I178V, T200A, E204K, Q207D, R211K, F214L, V245T, E248D, D250E, A272S, R284K, T286A, I293V, I329L, E344D, M357V, A360T, A376S, T386I, K390R, E404D  
ARV34 ARV34 None None  P236L I5V, V35T, E36A, T39K, V60I, K122E, D123S, I142V, K173A, Q174K, D177E, G196E, T200A, Q207A, R211S, V245E, D250E, T286A, E291D, V292I, I293V, P294T, I326V, G335D, M357K, G359S, K366R, A371V, I375V, A376T, K390R, E399ED, A400T, T403M M230N, L289F 
ARV41 ARV41 None None   V35T, E36D, K43N, S68G, D121H, K122E, D123E, I135V, S162A, K173A, Q174K, D177E, I178M, T200A, Q207E, V245Q, A272P, K275R, Q278N, T286A, V292I, I293V, E297A, S322T, G335D, R356K, M357K, G359S, A371V, I375V, A376T, V381I, K390R, T403M  
ARV47 ARV47 None None   V35T, V60I, S68G, T69N, L109I, D121H, K122E, I135V, T139K, D177E, T200E, Q207A, R211K, V245Q, L246I, E248N, D250E, T286A, E291Q, I293V, P294E, S322A, A327V, Q334H, G335D, R356K, M357R, R358G, G359S, K366R, T369A, A371V, I375V, A376S, T386I, Q394R, A400L, T403A, E413D  
ARV56 ARV56 None None   V21I, V35T, E36Q, T39D, K122E, D123K, I142V, S162C, K173T, Q174K, D177E, I178L, G196E, T200I, E203G, Q207N, R211K, V245Q, D250E, A272P, K275Q, Q278N, T286A, E291D, V292I, I293V, E297A, I329V, Q334L, G335D, F346Y, R356K, M357R, G359T, T369A, A371V, A376S, T377V, T386I, K390R, A400I, E404D  
ARV60 ARV60 None None   K11S, E28K, K32E, V35T, T39N, V60I, K122E, D123S, K173E, Q174R, D177E, I195T, T200A, Q207E, R211K, A272P, T286A, E291D, V292I, I293V, P294A, E297A, L301M, S322A, I329V, Q334H, G335D, T338S, R356K, M357R, G359T, T369A, T377Q, K390R, T397S, A400T, E404ED  
ARV64 ARV64 None None   V8VI, K20R, V35T, T39K, V60I, D123E, A158S, K173E, Q174R, D177E, T200A, Q207E, R211K, F214L, P243T, V245Q, E248D, D250E  
ARV80 ARV80 None None   K20R, V35T, S48T, V60I, V118I, D121H, K122E, S162C, K173T, Q174K, D177E, T200A, Q207A, R211K, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, P294V, E297A, R307K, S322T, F346H, M357I, R358K, G359S, E370D, T377L, K390R, A400T, E404D  
ARV81 ARV81 None None   K11S, V35T, K122E, D123N, A158S, K173S, Q174K, D177E, I178M, G196E, T200A, Q207E, R211K, V245Q, A272P, T286A, I293V, E312D, D324E, I326V, G335D, M357R, G359S, A371V, I375M, T377Q, T386I, E396D, T403M, E404D  
ARV93 ARV93 None None   V35T, V60I, D121H, K122E, I135V, K166R, F171Y, K173A, Q174K, D177E, I178L, T200A, Q207E, V245Q, E248D, D250E, A272P, K277R, E291D, V292I, I293V, E297T, I329V, Q334L, G335D, R356K, M357R, G359A, T369A, A371L, A376S, T377A, K390R, K395R, A400T, E404D, T409S  
ARV94 ARV94 None None   K20R, V35T, T39N, V60I, D121H, K122E, I135V, Q174R, D177E, I178L, V179I, T200A, Q207D, R211K, M230I, I244V, V245T, A272P, T286A, E291D, V292I, I293V, S322A, Q334L, G335D, R356K, M357R, R358G, G359S, A371V, I375V, V381I  
AS23 AS23 None None  M230L K11S, V35T, T39K, S48T, V60I, K122E, D123G, K173S, T200A, Q207D, V245Q, A272P, T286N, A288G, E291D, V292I, I293V, R307K, S322T, I329V, G335D, M357K, G359S, K366R, T369A, K390R, K395R, T403M, I411V  
CHU03 CHU03 None None   V35T, T39A, D121H, K122E, D123S, I135T, K173A, Q174R, D177E, I178IL, Q207E, R211K, V245E, A272P, K277R, K281R, E291D, V292I, I293V, P294T, E297K, V317A, S322T, G335D, M357K, G359S, K366R, T369A, A376T, T377M, K390R, K395R, A400T, E404D, Y405YN K166K*Q, T253S 
CHU06 CHU06 None None   V35T, K49R, V60I, K66X, V90I, K102Q, K122E, D123S, I135T, K173R, Q174K, D177E, I178M, T200A, Q207D, R211E, V245K, D250E, A272P, K275Q, L283I, T286A, E291D, V292I, I293V, E297A, D324E, L325I, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, V365I, T369A, A371V, T386I, K390R, Q394R, E399D, A400AV  
CHU07 CHU07 None None   E6D, K11Q, T27S, V35T, K49R, V60I, D121Y, K122E, D123G, S162A, D177E, T200A, Q207E, R211K, V245Q, D250E, I293V, I329L, Q334P, G335D, M357K, T369A, I375V, T377TN, S379SC  
CHU08 CHU08 None None   V35T, T39L, S48T, D123E, S162C, K173T, Q174K, T200A, Q207E, R211A, V245Q, E248D, A272Q, T286A, E291D, V292I, I293V, E312Q, D324E, I329L, G335D, G359S, K366R, T386I, K390R, A400T, I411L  
CHU09 CHU09 None None   E6N, K11S, K20R, V35T, T39N, I50F, V60I, K122E, D123N, S162D, K173S, I178M, E194K, G196E, T200A, E204Q, Q207A, R211K, V245Q, E248D, E291D, V292I, I293V, P294T, S322T, G335D, M357K, G359S, I375V, T386I, K390R, A400T, T403M  
CHU11 CHU11 None None   T27S, V35T, V60I, D123E, I135V, E169D, Q174K, D177E, G196E, T200A, R211S, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, D324E, L325I, G335D, I341F, F346Y, R356K, M357R, R358G, G359S, T369A, A371V, I375L, K390R, Q394R, A400T, E404D, E413D  
CHU12 CHU12 None None  Y181I, Y188S, G190N E28Q, K32Q, V35MT, T39A, G45GE, I50IL, K122E, D123N, K173Q, Q174K, N175I, V179L, D192N, R199RK, T200A, I202V, Q207A, E248D, K275Q, T286A, E291D, I293V, P294T, E312A, D324E, G335GD, R356G, M357K, R358G, G359S, A360T, K366R, E370A, I375V, A376S, T377M, K385R, T386I, K388R K49KN, I180S, Q182K, D186I, L187C, V189Q, S191L, H208S, L209S, E396V 
CHU13 CHU13 None None   V35T, K49R, V60I, D121H, K122E, D123G, I142V, K173S, D177E, T200A, Q207A, I244V, V245K, E248D, A272Q, K277R, T286A, E291D, V292I, I293V, T296S, E297K, A304E, G335D, R356K, M357R, G359S, A376S, V381I, T386I, Q394R, A400V, E404D  
CHU14 CHU14 None None D67E  K32I, V35T, K49R, I50V, E53D, V60I, K102Q, K122E, D123DN, I135R, D177E, I178M, Q207A, R211K, I244V, V245T, A272P, V276T, K277R, L283I, E291D, V292I, I293V, E297R, A304E, K311R, D324E, Q334E, R356K, M357I, G359A, T386I, K390R, E399D, A400T, Y405H, P421Y N57K, L80L_I, N81K 
CHU16 CHU16 None None  V179E V21I, V35I, I50N, P52A, V60I, K102Q, K104R, K122E, D123S, I135T, S162C, K173T, D177E, I178L, T200A, Q207D, R211K, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, E297A, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A360T, K366R, V381I, T386I, Q394R, E399D, A400V G51R, E224E_PPSQR 
CHU17 CHU17 None None   K20R, V35T, V60I, K64R, K102Q, K122E, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, P243S, V245Q, E248D, S251C, K281R, E291D, V292I, I293V, E297A, S322E, D324E  
CHU18 CHU18 None None   P4S, V35T, K122E, D123G, S162A, K173T, Q174K, D177E, Q197E, T200A, E204K, Q207E, R211K, V245Q, A272S, K275Q, I293V, L295M, E312N, S322A, D324E, G335D, R356K, M357K, G359S, K366R, T369A, A371V, I375V, A376C, K390R, K395R, A400T K11V 
CHU19 CHU19 None None   E6K, V35T, K49R, V60I, K102Q, K122E, D177E, I178M, Q207E, R211K, V245N, D250E, A272P, K277R, T286A, E297K, I329L, G335D, R356K, K390R, E404D  
CHU27 CHU27 None None   E6K, K20R, V35T, K49R, V60I, K122E, I135T, D177E, G196A, Q207E, V245K, D250E, A272P, K281R, T286A, I293V, E297K, Q334H, G335D, R356K, I375M, T386I, K390R, E404D, P412L  
CHU29 CHU29 None None   T27S, V35T, E36K, T39A, D121Y, K122E, I135T, E138A, S162C, K173T, Q174K, P176Q, G196E, T200I, Q207E, R211K, F214L, V245Q, D250E, S251D, A272P, T286A, A288S, V292I, I293V, E297K, R307K, E312D, V317A, P321S, S322G, D324E, I329V, Q334L, G335D, R356K, M357R, V365I, A371L, T377L, K390R, A400T, E404D  
CHU30 CHU30 None None   V35T, T39S, E40D, K122E, I135L, S162A, E169D, K173T, Q174K, I178M, T200A, Q207E, V245Q, A272S, T286A, E291D, V292I, I293V, P294T, K311R, V314A, S322A, M357K, R358K, K366R G359FS 
CHU31 CHU31 None None   K20N, V35T, E36D, K49R, V60I, D123E, K166R, D177E, T200A, Q207E, R211K, P243A, V245R, K263N, A272P, K277R, T286A, I293V, M357A, A360T, I375V, T377V, K390R, E399D, A400T  
CHU33 CHU33 None None   E6Q, K11S, K32E, V35T, T39K, K122E, D123N, I135T, S162C, K173A, D177E, T200A, Q207R, R211E, V245K, K281R, E291D, V292I, I293V, P294T, E297K, S322T, I329V, G335D, M357K, G359S, K366R, A371V E28N 
CHU35 CHU35 None None   E6K, K20R, V35T, K49R, V60I, K122E, I135T, D177E, G196A, Q207E, R211K, V245K, D250E, A272P, K281R, T286A, I293V, E297K, Q334H, G335D, R356K, I375M, T386I, K390R, E404D  
CHU38 CHU38 RTI RTI M41L, T215Y Y181C V35T, K49R, I50V, V60I, K102Q, K122E, D123S, I135T, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, L228R, V245Q, D250E, A272P, L283I, V292I, I293V, E297A, D320N, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, E370D, A371V, T377M, T386I, K390R, Q394R, E399D, A400V, E404D, E413D, Q428R, K431T  
CHU39 CHU39 None None  V179E V35T, T39A, K122E, I135R, K173E, D177DE, E204D, Q207N, R211K, V245K, D250E, A272P, K275KR, K277R, T286A, I293V, P294Q, E297K, Q334L, G335D, R356K, K390R, E399EK, A400T, T403V  
CHU43 CHU43 None None   V35T, T39A, E40D, K122E, D123N, K173T, D177E, T200K, I202V, V245Q, D250T, S251D, K275Q, K277R, T286A, E291D, V292I, I293V, E297A, S322G, D324E, E328D, Q334E, F346Y, R356K, M357R, R358G, G359S, I375V, T377I  
CHU46 CHU46 None None   V35T, E40ED, K49R, V60I, K122E, D123S, K173T, D177E, T200A, Q207K, V245Q, D250E, S251D, A272P, T286A, E291D, V292I, I293V, L295M, E297A, K311R, I326V, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, T369A, A371V, I375IV, T377L, S379A  
CHU50 CHU50 None None   K20R, V35T, V60I, T69A, D121H, K122E, D123E, K173I, Q174K, Q207K, R211A, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E297A, D324E, E328D, G333E, Q334G, P345Q, F346Y, M357T, G359S, V365I, K366R, T377Q, K390R, A400T  
CHU51 CHU51 None None   V35T, K49R, V60I, K122E, R125K, I142V, K173T, Q174K, D177E, I178M, Q207E, R211K, V245Q, E248D, A272P, K281R, T286A, E291D, I293V, E297A, K311R, D324E, I326V, I329V, Q334H, G335D, F346H, M357R, G359S, A371V, A376S, T377I, T386I, K390R, A400T  
CHU53 CHU53 None None   V35T, E40D, K49R, I50V, V60I, D121Y, K122E, T139A, K173Q, D177E, I178V, T200A, E204K, Q207E, R211K, F214L, V245T, D250E, D324E, I329L, K366R, T377Q, K390R, E404D  
CHU56 CHU56 None None   V35T, T39N, E40D, K49R, V60I, V106I, K122Q, I142V, D177E, T200A, Q207E, R211K, V245Q, E248D, D250E, A272P, Q278H, T286A, E291D, V292I, I293V, E297A, L301M, D320E, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, T386I, K390R, Q394R, A400V, Y405C  
CP03 CP03 None None   K20R, V35T, T39M, E40D, K49R, V60I, W88C, K122E, D123N, I135T, E138A, T200A, Q207E, F214L, P243A, V245K, D250E, T286A, I293V, P294T, E297K, K311R, R356K, G359S, E370D, A376T, T377Q, S379C  
CP06 CP06 None None   V35T, T39L, K102Q, K122E, D123S, E138A, T139V, S162C, K173A, Q174K, D177E, T200M, Q207D, R211K, P243S, V245Q, E248D, D250E, A272P, L283I, I293V, E297A, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, T386I, K390R, Q394R, E399D, A400V, Q428R  
CP07 CP07 None None   V35T, V60I, T107S, K122E, D123N, D177E, I178M, T200A, Q207A, R211K, P243A, I244V, V245K, K249Q, A272P, E291D, V292I, I293V, E297R, K311R, V317A, G335D, M357T, G359S, V365I, A376S, S379G, I380V, V381I  
CP10 CP10 None None   V35T, E40D, V60I, K122E, D123S, K173A, D177E, T200A, Q207E, V245K, D250E, L283I, E291D, V292I, I293V, E297A, E312D, D324E, I329V, G335D, F346Y, R356K, M357R, R358G, G359S, K366R, A371V, T377R, K390R, A400T, E404D  
CP11 CP11 None None   K20R, V35T, E40D, E44D, K49R, I50IL, E53D, V60I, V118I, K122P, P170S, K173A, Q174K, D177E, I195L, T200A, Q207K, R211E, F214L, V245Q, T286A, E291D, V292I, I293V, E297A, I326V, Q334H, G335D, R356K, M357R, R358K, G359S, T369V, A371V, T377Q, S379A, A400T L34LF 
CP13 CP13 None None   P4H, K11S, V35T, T39K, K122E, D123S, S162C, K173S, T200A, Q207A, R211S, L228Q, V245Q, A272P, K277R, K281R, E291D, I293V, P294A, E297K, S322T, G335D, R356K, M357K, G359S, K366R, K390R, A400T, T403M, E415V  
CP14 CP14 None None   V21I, V35T, E36Q, T39D, K122E, D123K, I142V, S162C, K173A, Q174K, D177E, I178L, G196E, T200I, Q207N, R211K, V245Q, E248D, D250E, A272P, K275R, V276I, L283I, E291D, V292I, I293V, E297A, S322T, D324E, I329V, Q334L, G335D, R356K, M357R, G359T, T369A, A371V, A376S, T377V, T386I, K390R, A400I, E404D  
CP15 CP15 None None   K11T, V35T, T39K, D123S, K173L, Q174A, D177E, T200A, Q207N, R211K, V245Q, V292I, I293V, E312T, G335D, M357K, G359S, K366R, T369A, K374R, I375V, T377Q, K395R  
GB03 GB03 None None   K20R, V35T, T39A, E40X, G45X, K46X, V60I, T107S, K122E, D123E, I135A, E169Q, K173T, Q174K, D177E, I178M, T200A, I202M, Q207G, R211K, T215X, D218E, Y232*, V245Q, E248D, D250E, S251D, L260X, A272P, K277R, Q278H, T286A, E291D, V292I, I293V, P294A, E297A, L301M, I329V, G333E, Q334L, F346Y, R356K, M357R, R358G, G359S, A371V, I375V, S379G, V381I, T386X, Q394X, E399D, A400V, I411X, E413X Q23H, K30E, L210R, V261M