<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Rusine (2013)
Title Low primary and secondary HIV drug-resistance after 12 months of antiretroviral therapy in human immune-deficiency virus type 1 (HIV-1)-infected individuals from Kigali, Rwanda.
Citation PLoS ONE
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 119
NumPts 109
Subtype A, C, D

 

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Page 1   listing Isolate 1 to Isolate 100 from Total 119 Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
401H 401H None None   V35T, E36A, T39E, I47L, S48ST, K122E, A158S, K173AT, D177E, T200A, Q207E, R211K, V245Q, E248Q, A272P, T286TA, E291D, V292I, I293V, V317A  
403H 403H None None   V35T, S48T, K122E, D123S, I135T, S163ST, T165I, K173A, Q174K, D177E, T200TI, Q207GS, R211S, V245Q, A272AP, L283I, E291ED, I293V, P294T, L295M, E312D V60VIM 
404H 404H None None   V35T, T39E, K122E, E138A, I142IV, K173T, Q207D, R211K, V245KLMQ, E248DN, D250DE, S251X, A272P, K277R, T286TA, V292I, I293V, V317A  
405H 405H None None   V35T, K49R, K122D, D123S, K173A, D177E, V179I, Q207A, R211S, V245Q, E248D, I293V, P294T, E312D, V317G R72G, Y127D, S268R 
406H 406H None None   V35T, T39TA, K122E, I135T, I142V, K173AS, Q174K, D177E, V179I, T200A, Q207A, R211S, F214L, V245Q, E248EDKN, D250DE, S251ST, A272P, K281KR, T286A, E291D, I293V, E312D  
   AZT, 3TC NVP   V35T, K122E, I135T, I142V, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, F214L, V245Q, E248D, T286A, E291D, I293V, E312D  
407H 407H None None   V35T, S48E, K49R, V60I, K122E, D123G, I135T, K173S, Q174K, D177E, Q207A, R211S, V245E, D250E, T286A, I293V, P294T  
408H 408H None None   K11KT, V35T, K49R, I50IV, E53ED, V60VI, K122E, D123NS, I135IT, K173ALSV, Q174K, D177E, V179VI, T200TA, Q207ADE, R211RS, F214FL, V245HKNQ, E248D, A272P, K277KR, K281KR, T286TA, E291ED, V292VI, I293V, P294PT, L295LIM, E312D, P321PS, S322ST  
409H 409H None None   K11T, V35T, T39A, E40D, V60I, D121Y, K122E, I135T, I142V, K173S, Q174K, D177E, V179I, Q207A, R211S, V245K, D250E, T286A, E291D, V292I, I293V, P294T, E312D, D320E, S322L  
410H 410H None None   V35T, V60I, K102Q, K122E, I135T, K173L, Q174K, D177E, V179I, T200A, Q207A, R211S, V245Q, D250E, K277R, T286A, E291D, V292VI, I293V, P294T, D324E  
413H 413H None None   K11KR, V35T, V60VI, K122E, D123N, I135T, K173S, Q174QKR, D177E, V179I, T200TA, Q207A, R211S, V245Q, D250DE, K281R, I293V, P294T, E297K, E312D  
414H 414H None None   K20KR, V35T, E36EA, T39E, S48T, K49KR, V60VI, K122E, D123NS, K173A, Q174K, D177E, I178ILM, T200A, R211RK, K238KR, P243T, V245Q, E248D, D250DE, A272P, T286TA, E291D, V292I, I293V, A304AE  
415H 415H None None   E6K, K11T, V35T, T39TA, K122E, D123N, I135T, I142V, K173S, Q174K, D177E, V179I, G196E, T200TA, Q207A, R211NS, F214L, V245H, A272AS, T286A, E291D, V292I, I293V, E312D, G333E  
416H 416H None None   V35T, K122E, D123N, I135T, I142V, K173S, Q174K, D177E, V179I, Q207A, R211K, P243PS, V245Q, K249KQ, D250DG, S251T, K275R, V276I, I293V, P294T, K311R, E312H  
417H 417H None None   K11T, V35T, K122E, D123G, K173AT, Q174QK, D177E, I178IM, V179I, Q207A, R211S, V245Q, E248D, S251T, A272AP, T286A, E291D, I293V, P294A, K311KR, E312D, S322SL, D324DE, I326IM, A327V, I329IV  
418H 418H None None   K11KT, V35T, K49R, V60I, D123S, I135T, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, V245Q, K281R, L283I, K287KR, E291ED, I293IV, P294T, L295M, E312D  
419H 419H None None   V35T, K43KR, K49R, I50V, I135T, T139A, K173S, D177E, I178V, Q207A, R211S, F214L, V245Q, D250E, A272P, K281R, E291D, I293V, E312D, H315Q  
420H 420H None None   K11E, V35T, V60I, D121H, K122E, D123S, I135T, K173S, Q174K, D177E, V179I, T200A, Q207AD, R211NS, V245Q, D250E, K281KR, T286A, V292VI, I293V, P294IT, E297K, E312D  
423H 423H None None   K11T, V35T, E40D, K49R, K122E, D123NS, I135T, T139V, K173S, Q174KR, D177E, V179I, T200TA, Q207A, R211NS, V245Q, T286A, E291D, I293V, P294PT  
424H 424H None None   K11T, V35T, I47L, S48T, K49R, D123N, I135T, K173L, D177E, V179I, T200A, Q207A, R211S, V245Q, V261I, E291D, I293V, P294T, E312D K122EG 
426H 426H None None   K11S, K32X, V35T, T39K, K122E, D123NS, I135K, K173S, T200A, Q207T, R211K, V245KQ, E248EDKN, D250DE, L283LI, I293V, P294T, E312D  
427H 427H None None   V35T, E36A, T39E, S48T, K122E, K173A, Q174K, D177E, V179I, T200TI, I202V, Q207DE, R211K, K281R, T286A, E291D, V292I, I293V, E312N  
430H 430H None None   V35T, K49R, I50V, V60I, K122E, D123S, I135T, K173S, Q174K, I178M, V179I, T200A, Q207A, R211S, I257IL, V261I, V276VI, K281R, T286A, E291D, V292I, I293V, P294PT, E312D  
431H 431H None None   E6EK, K11T, V35T, K122E, D123G, I135T, I142IV, S162Y, K173S, D177E, V179I, Q207A, R211S, F214L, V245Q, E248D, D250E, K281R, I293V, P294A, L295M, E312D  
432H 432H None None   K11T, V35T, K49R, K122E, D123G, I135T, K173S, Q174H, D177E, V179I, T200A, Q207A, R211S, F214L, V245KLMQ, S251N, A272P, K275Q, V276I, K281R, T286A, E291D, I293V, P294T, E297K, E312D  
433H 433H None None   K20KR, T27TS, V35IT, E40D, K49R, V60I, A158AS, K173T, D177E, T200A, Q207E, V245Q, A272P, K277KR, T286A, E291D, V292I, E312D, P321S  
435H 435H None None   P4PH, V35T, T39K, K43Q, S48T, K49KR, V60VI, K102KR, K122E, D123NS, I135T, K173S, Q174QK, D177E, V179VI, E194ED, T200A, Q207A, R211K, V245Q, V276VI, K277KR, Q278HNRS, K281KR, T286A, I293V, P294T, E312D, S322SA K11LS 
436H 436H None None   E6K, K11T, V35T, E40ED, K49R, I50IV, V60I, K122E, D123N, I135T, I142V, K173L, D177E, V179I, V189VI, T200TA, Q207A, R211S, K223KR, V245K, T286TA, E291ED, I293IV, P294T  
443H 443H None None   I5IV, P9PS, V35T, K49R, V60VI, K122E, D123S, I135IT, S162SAGT, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, V245Q, D250S, A272P, E291D, I293V, E312N  
444H 444H None None   V35T, V60VI, K122E, D123N, I135T, I142V, K166KR, K173S, D177E, V179I, T200TA, I202V, Q207A, V245Q, K277R, K281KR, T286A, I293V, P294T, E312DN, V317A  
445H 445H None None   K11T, K20R, V35T, T39A, E40D, K49R, V60VI, K122E, D123S, I135T, K173S, Q197K, Q207A, R211S, F214L, V245M, A272P, T286A, I293V, P294T, E312D, Q334QK  
447H 447H None None   V35T, V60I, K122E, D123S, K173S, T200A, Q207A, V245X, E248EDKN, D250DE, S251C, A272P, K277R, T286TA, I293V, P294PT, E312D  
448H 448H None None   P4PT, E6KQ, V35T, K49R, D121DH, K122KE, D123DGNS, I135T, K173AT, D177E, V179I, I195L, Q207A, R211S, V245Q, A272P, I293V, P294T, E312D K11KPQT 
450H 450H None None   K11T, V35T, T39M, K49R, K122KDEN, I135T, S162T, K173AS, D177E, T200K, K201R, Q207E, R211K, V245Q, A272P, V276T, K277R, K281KR, L283I, E291D, V292VI, I293V, S322SA D121CHRY 
451H 451H None None   E6D, V35T, T39A, K49R, K122E, D123S, I135T, I142V, S162C, E169K, K173S, Q174K, T200A, E203D, Q207A, R211S, D250E, A272P, K275Q, T286A, E291D, V292I, I293V, E297R, E312D, I326V  
455H 455H None None  K103KN V35T, T39E, S48T, V60VI, K122E, D123S, I135R, K173A, Q174K, Q197QP, T200A, Q207E, R211RK, V245Q, A272P, Q278H, K281R, T286A, E291D, V292I, I293V  
456H 456H None None   V35T, K46KQ, I47L, V60VI, D121H, K122E, D123S, K173AS, Q174K, D177E, T200TA, Q207A, R211S, V245E, K281KR, E291ED, I293V, P294T, L295M, E312D  
457H 457H None None   V35T, I50V, V60I, D121HY, K122E, I135T, I142V, K173S, Q174KR, D177E, I178IM, V179I, E194EG, G196E, T200A, Q207A, R211S, D250DE, S268SC, A272P, K275Q, T286A, I293V, P294T, E297K, E312D, I326IV  
460H 460H None None   P4H, K11T, K20R, V35T, V60I, K64R, D121H, K122E, D123G, I135T, I142V, S162A, T165I, K173S, Q174K, D177E, V179I, G196E, T200I, Q207A, R211S, D250DE, A272P, T286A, E291D, I293V, P294A, E312S, P321S, D324E  
461H 461H None None   V35T, T39KR, K43E, K122E, D123S, S162C, D177E, Q207E, R211K, V245E, D250E, K281KR, T286A, E291D, I293V, E312N  
463H 463H None None   V35T, T39K, K122E, D123NS, I135T, S162CY, K173AS, D177E, V179VI, T200A, Q207A, R211S, V245Q, E248D, K277R, T286A, E291D, I293V, P294T, E297Q, E312D  
465H 465H None None   V35T, E36A, T39E, K122E, D123DG, I135T, I142V, K173AS, Q174QK, D177EG, T200AE, Q207A, R211NS, F214FL, V245K, D250E, A272P, V276T, E291D, I293V, E312D  
466H 466H None None   V35M, T39I, K49KR, K122E, D123S, I135T, Y144YF, K173L, Q174K, D177E, V179I, T200A, Q207A, V245EK, D250E, T286A, E291D, V292VI, I293V, E312D  
469H 469H None None   V21I, V35T, T39A, V60I, K64KR, D121H, K122E, D123N, I135T, S162HY, K173S, Q174K, D177E, V179I, Q207A, V245K, D250DE, S251H, A272P, K275Q, K281R, T286A, E291D, V292I, I293V, P294T, R307RK, E312D, D324DE  
473H 473H None None   K11S, V21I, V35T, T39TA, E40ED, K49R, I50V, V60I, K102Q, K122E, D123G, I135T, K173S, D177E, I178IM, V179VI, T200A, Q207A, R211S, V245Q, T286A, E291D, V292VI, I293V, E312D  
477H 477H None None   V35T, T39A, K122E, D123S, I135T, S162C, F171Y, K173S, Q174K, T200A, Q207A, R211S, F214L, S251I, A272S, T286A, K287R, I293V, P294T, E312D  
479H 479H None None   V35T, I47L, S48T, V60I, K122E, D123N, I135T, T165I, K173A, Q174K, V179I, Q207A, R211S, K223R, V245KQ, A272AP, K281KR, T286A, E291D, V292I, I293V, P294T, E297K, E312D, I326V  
481H 481H None None   V35T, K43KR, K49KR, V60I, K122E, D123GS, K173S, Q174K, D177E, Q197K, T200A, Q207E, R211K, V245Q, A272P, T286TA, E291D, V292I, I293V  
483H 483H None None   V35T, E36A, T39E, K43R, S48T, K122E, D123N, Q145C, K173A, D177E, T200A, Q207E, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V  
484H 484H None None   K11R, V35T, I47L, K49R, V60VI, K122E, D123NS, I135T, I142V, K173A, Q174QR, D177E, Q207A, R211S, V245Q, K277R, T286A, E291D, I293V, P294T, E312D  
485H 485H None None   V35T, E40ED, K49KR, V60VI, K122E, D123N, K173S, D177E, V179I, Q207A, R211S, V245Q, A272P, E291D, V292VI, I293V, P294AT T253TS 
487H 487H None None   K11T, V35T, T39TA, S48T, V60VI, K122E, D123N, I135T, I142V, K173AT, Q174QK, D177E, I178IM, T200A, Q207E, R211K, V245Q, D250DE, A272P, K277KR, T286TA, E291D, V292VI, I293V, L301LIM, K311KR, V317VA  
502H 502H None None   V35I, S48T, V60I, D121Y, K122E, I142V, K173L, Q174K, D177E, Q207A, R211S, V245E, D250E, V254I, K277R, T286A, E291D, V292I, I293V, V317A  
701H 701H None None   K11T, V35T, T39A, E40D, K49R, K122E, D123S, I135T, I142V, K173L, Q174K, D177E, V179I, Q207A, R211S, V245Q, K275Q, K277R, I293V, P294T, E312D  
702H 702H None None   K20R, V35T, V60VI, K64KR, K122E, D123N, I135T, K173S, V179I, T200A, Q207A, R211S, V245K, D250E, T286A, E291D, V292VI, I293V, P294PA, E297EK, A304AE, E312ED  
703H 703H None None   V35T, T39K, K43KE, K122E, D123S, K126KR, I142F, K173A, I178L, T200A, Q207A, R211N, V245KT, E248D, T286A, E291D, I293V, P294T, L295F, L310I, I326V  
704H 704H None None   E6K, V8I, K11A, G15GE, V35T, K43KR, I47L, K49KR, I50V, V60I, K122E, D123N, I135T, S162D, K173S, D177E, V179I, T200TA, Q207A, R211S, V245Q, T286TA, I293V, P294T, E312D  
705H 705H None None   E6D, K11T, V35T, S48T, K49KR, V60I, K122KE, D123DGNS, I135T, K166KR, K173A, D177E, V179I, Q207A, R211S, V245Q, D250E, V276I, K277R, T286TA, I293V, P294T, E312D, V317VA, P321S S162ADHP 
706H 706H None None   E28EG, V35E, T39A, K122E, D123N, I135T, I142T, K173AS, Q174K, D177E, V179I, Q207A, R211S, V245Q, T286A, E291D, V292I, I293V, P294T, E297ED, P321PS, I329IV  
707H 707H None None   V35T, E36EA, T39E, E40D, I47IL, S48T, K49R, V60VI, K82R, K122E, Y144F, K173T, Q174K, D177E, V179I, Q197QK, T200E, Q207A, R211RK, D250E, K281KR, E291D, V292I, I293V, E312D  
708H 708H None None   V35T, E36A, T39E, E40ED, K43KR, I47L, K122E, D123S, K173AT, Q174QK, D177E, I178L, T200A, Q207E, R211RK, V245Q, A272P, K277KR, T286A, E291D, V292I, I293V, P294Q, E297A, L301F, V317A  
709H 709H None None   K11T, V35T, T39A, E40ED, K122E, D123N, I135T, I142V, K173E, Q174K, D177E, V179I, T200TA, Q207AT, R211S, F214L, D237E, V245H, K281R, E291D, V292VI, I293V, P294PA, K311KR, E312NT  
711H 711H None None   V35T, T39L, K122E, D123X, I135T, S162A, K173S, Q174QK, T200A, Q207A, R211S, V245KQ, A272P, E291D, I293IV, P294PT, L295M, K311KR, E312D  
712H 712H None None   V8VI, V35T, T39TA, E40D, K49R, V60I, D121Y, K122E, D123E, I135T, E169D, D177E, V179I, T200A, Q207N, R211K, V245M, E248D, D250E, A272S, K277KR, Q278E, T286A, E291A, I293V, E297EA, V317VA, S322T V292G 
713H 713H None None   V35T, T39A, I47L, V60VI, K122E, D123NS, I135T, I142IV, S162AD, K173S, D177E, V179VI, T200A, Q207A, R211RS, F214FL, V245Q, K281KR, I293V, P294T, E312D  
714H 714H None None   V8VI, V35T, T39TA, K49KR, K104KR, K122E, D123G, I135T, I142V, P170PT, K173S, Q174KR, D177DE, I178IM, V179I, T200A, Q207A, R211NS, I274IV, K275R, V276VI, T286A, E291D, V292VI, I293V, P294T  
715H 715H None None   V35T, E36A, T39D, S48T, K122E, D123S, I135T, Q145V, A158S, K173A, T200A, Q207G, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
716H 716H None None   V35T, E36A, T39E, E40ED, K122E, D123N, I135T, S162C, K173S, D177DE, V179VI, T200A, I202V, Q207A, R211S, V245Q, E248D, K281R, I293V, P294T, V317A, D324DE  
719H 719H None None   V21I, V35T, T39TA, E40D, S48ST, K49KR, I50IV, V60I, K122E, D123N, I135T, S162A, T165I, K173AS, Q174K, D177E, V179I, T200A, I202V, Q207A, V245Q, K281R, E291D, I293V, P294A, E297K, E312D  
720H 720H None None   V35T, K49KR, V60VI, T69TS, K122E, D123GS, I135T, S162A, K173AS, V179I, T200TA, Q207ADE, R211K, F214FL, V245Q, T286A, I293V, P294T, E312D, V317A, D324DE  
722H 722H None None   K11T, V35T, E40D, K49R, V60VI, K122E, D123G, I135T, K173S, Q174K, D177E, V179I, T200TA, Q207A, R211S, F214L, V245Q, E291D, I293V, E312D  
723H 723H None None   K11T, V35T, T39TK, V118I, K122E, D123S, I135T, K173AS, D177E, I178IV, V179I, T200A, Q207A, R211S, F214L, V245Q, E248D, K281R, I293V, P294T, E305*, E312D, I326IV, Q334R D256Y, V261L 
724H 724H None None   E6K, V8I, K11T, V35T, E36D, T39R, K43Q, S48ST, V60I, V118I, K122E, D123N, K173L, Q174K, D177E, V179I, Q197K, T200E, Q207A, R211S, F214C, H221Y, L228H, V245E, E248Q, A272P, L283I, I293V, P294T, L295M  
725H 725H None None   V35T, K49R, V60I, K122E, D123N, I135T, K173S, Q174K, D177E, I178M, V179I, T200TA, Q207A, R211S, V245E, D250DE, K281R, I293V, P294T, L295M, E297K, E312D, V317VA  
728H 728H None None   V35T, E40D, V60I, D121H, K122E, D123S, I135T, I142IV, S162SAGT, K173S, Q174R, D177E, V179I, T200A, Q207A, R211S, F214FL, D250E, A272G, T286A, E291D, V292I, I293V, P294T, E312D  
729H 729H None None   V35T, T39M, S48T, V60I, T69S, K122E, D123N, I135T, I142V, K166KR, K173S, D177E, V179I, Q207A, R211K, V245E, E248N, K277R, I293V, P294A, E312N, D324DE I31FL 
730H 730H None None   V35T, T39L, V60I, D121Y, K122E, I135T, Q145C, S162A, D177E, T200I, Q207E, R211K, V245Q, D250E, L282C, T286TA, V292I, I293V, E297Q  
732H 732H None None   E6KR, K11T, V35T, K49R, V60I, K122E, D123N, I135T, I142IV, S162D, K173LV, Q174K, D177E, I178IM, V179I, I195L, Q207A, R211S, F214L, V245Q, K281R, A288S, V292VI, I293V, P294T, E312D, V317A  
733H 733H None None   V35T, T39L, K122E, D123E, A158S, K173V, D177E, I178IM, G196GV, T200A, Q207S, R211K, V245KPQT, E291ED, I293V, P294T, E312D, I326V  
734H 734H None None   K11T, K20R, V35T, K49KR, V60I, K122E, D123GS, I135T, D177E, V179I, T200A, Q207A, R211S, V245Q, K281KR, T286A, I293V, P294T, E312D, I326T K173FS 
735H 735H None None   V35K, S48T, K173T, T200A, I202V, Q207E, R211K, P243T, V245Q, A272P, V292I, I293V, K311R  
736H 736H None None   V35T, E36A, T39E, E40D, K49R, E53D, D121Y, K122E, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, E291D, V292I, I293V, V317T  
743H 743H None None   V35T, V60I, D121HY, K122E, D177E, I178IM, T200M, Q207EK, R211K, V245K, D250E, K277KR, K281KR, L282C, L283I, T286A, I293V, D324E  
744H 744H None None   E6K, V35T, T39A, E40D, K49KR, I50IV, V60I, S68SG, K122E, D123S, K173L, Q174K, D177E, Q207A, R211S, V245M, A272P, T286A, E291D, V292I, I293V, P294T, E312N S48S*AE 
747H 747H None None   I5IV, E6EGKR, V21I, V35T, E40D, K49R, V60I, K122E, D123GS, I135T, S162SHNR, K173S, Q174K, D177E, T200TA, Q207A, R211S, V245E, D250E, T286A, E291D, V292VI, I293V, P294AT, E312D  
748H 748H None None   V35T, E40D, K49R, I50IV, V60I, K122E, D123S, T139L, S162D, K173S, Q174K, D177E, I178IM, V179I, T200A, Q207A, R211S, V245Q, E248N, A272P, Q278H, T286A, V292I, I293V, L310I  
749H 749H None None   K32KR, V35T, E36A, T39E, E40D, S48T, K64KR, K122E, E138A, A158S, S162A, K173T, D177E, I178V, V179VI, T200A, Q207D, R211K, F214L, V245Q, A272P, T286A, E291D, L310I, D324DE  
750H 750H None None   K11AST, K20KR, V35T, V60VI, K102KR, K122E, D123GS, I135T, S162A, K173S, Q174K, D177E, V179I, T200S, Q207A, R211S, V245Q, D250E, T286TA, I293V, P294T  
751H 751H None None   V21I, V35T, E40ED, K49R, I50V, V60I, K122E, D123S, I135T, K173S, Q174K, D177E, Q207A, R211S, V245E, D250E, T286A, E291D, V292I, I293V, P294A, E312D, S322A  
754H 754H None None   V35T, E40D, K49R, K122E, D123GS, K173T, Q174HR, D177E, I178M, T200A, Q207D, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, K311R T253N 
757H 757H None None   V35T, E36A, T39DE, E40ED, K49R, E53D, K122E, D123G, I142V, K173A, D177E, Q197QH, T200A, Q207E, V245Q, D250E, K277R, T286A, E291D, I293V, P294T, V317VA, D324E V292IR 
758H 758H None None   V60I, K122E, D123N, I135T, I142T, T165TI, K173S, Q174K, V179IT, G196E, Q207A, R211S, F214L, V245Q, I293V, P294AT, E312D  
759H 759H None None   V35I, E36A, T39E, I47L, S48T, K122E, D123NT, A158S, K173S, Q174K, V179I, T200TA, Q207A, R211RK, S251AT, A272P, K275KQ, T286A, E291ED, V292I, I293V, P294T, L295LM, V317VA, E328D  
761H 761H None None   E6K, K11T, V35T, T39AE, E40D, K49R, K122E, D123N, I135T, I142V, K173S, Q174R, D177E, V179I, I195L, T200A, I202V, Q207A, R211S, F214L, V245Q, A272P, I293V, P294T, E312D  
762H 762H None None   V35T, K49KR, V60I, K173S, Q174K, D177E, V179I, Q197E, T200TI, Q207A, R211N, V245E, D250E, T286A, E291D, V292I, I293V, P294T, E312D, V317A T253S 
763H 763H None None   E28A, V35T, E40ED, I47IL, K49R, I50V, V60I, A98S, K122E, D123G, I135T, K173S, D177E, V179I, T200TA, Q207A, R211S, V245E, D250DE, K281R, T286A, E291D, V292I, I293V, P294T, E312D, I326IT  
764H 764H None None   K11Q, V35T, T39E, V60I, D121H, K122E, D123S, I135K, I142V, K166R, K173T, D177E, T200E, Q207E, V245Q, E248ED, D250E, A272P, K277R, T286A, E291D, V292I, I293V, P294T  
766H 766H None None   K11T, V35T, E40D, K49R, V60I, K122E, D123N, I135T, K173S, V179I, Q207A, R211K, V245Q, E248N, D250E, S251IT, K275Q, I293V, P294T, E312D  
767H 767H None None   K11T, V35T, V60I, K122E, D123N, K173S, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S, V245Q, L283LI, I293V, P294T, L295M, K311KR, E312ED  
768H 768H None None   V35T, E40D, V60I, D121H, K122E, I135T, I142V, K173A, Q174K, D177E, V179I, Q207A, R211S, K281R, T286A, E291D, V292I, I293V, P294T, E312D