<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Rawizza (2013)
Title Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria.
Citation PLoS ONE
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 55
NumPts 55
Subtype CRF02_AG, G, CRF06_cpx, A, C

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
LL0499 LL0499 NRTI NNRTI D67G, K70R, M184V, K219Q Y181C K11T, K20R, V35T, T39S, V60I, T69N, D121Y, K122E, I135T, T139R, E169D, K173A, Q174K, D177E, V179I, G196E, T200A, E203V, Q207A, R211K, F214L, L228H, Q242H, D250E, A272P, L283I, E291D, I293V, E312D, Q334E  
LL2169 LL2169 NRTI NNRTI M184V, T215Y A98G, K103N K20R, V35T, E40D, K49R, V60I, S68G, K102KR, K122E, D123N, I135L, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, V245Q, S251N, A272P, T286A, E291D, V292I, I293V, I329V  
LL3229 LL3229 NRTI NNRTI M41L, D67N, K70R, M184V, T215F, K219E A98G, K103N K20R, V35T, V60I, K122E, K173T, Q174K, D177E, I178M, T200A, E203K, Q207E, H208Y, R211K, V245Q, E248D, A272P, E291D, V292I, I293V, E297K  
LL3779 LL3779 NRTI NNRTI M41L, D67N, K70R, V75I, M184V, T215F, K219Q A98G, Y181C S3C, I31L, K122KE, S162A, I167IV, Q174N, D177E, T200A, I202V, Q207E, R211RK, V245Q, D250E, S251D, A272P, T286A, V292I, I293V, S322T T39*AES 
LL4419 LL4419 NRTI NNRTI A62V, V75I, F77L, Q151M K103N, Y181C A33V, V35T, T39L, T69N, K101KR, V111I, V118VI, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, I178M, G196E, T200A, Q207E, F214L, H221Y, L228R, P243H, V245E, E248D, K275R, T286A, E291D, P294T, V317A, D320DE, S322T, I329V  
LL4420 LL4420 NRTI NNRTI   V35IT, T39A, V60I, S68G, D123E, I135V, I142V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207EG, R211K, V245Q, D250E, S251D, K281R, T286A, E291D, V292I, I293V, E312N, I326IV  
LL5290 LL5290 NRTI NNRTI M41ML, M184V, L210L*W, T215Y G190A V35T, E36D, I47IL, K49R, V60I, I135IV, K173T, Q174K, D177E, V179IL, E194ED, Q207D, R211K, V245Q, E248ED, D250E, S251D, A272AP, T286A, E291D, I293V, P294T  
LL5299 LL5299 NRTI NNRTI M41L, M184V, T215Y Y188L V35T, E36D, K49R, V60I, K122E, D123E, I135V, S162A, E169K, K173T, Q174AE, D177E, T200A, Q207E, K238R, V245Q, E248D, A272P, K281R, T286A, E291D, V292I, I293V, P294T, S322A  
LL5309 LL5309 NRTI NNRTI M41L, D67N, T215Y K103N T7TP, E28K, K32E, L34I, V35T, T39X, V60I, V90VI, V118I, D121H, K122E, I142V, Q174S, D177E, I178F, G196E, T200A, E203D, Q207D, H208Y, R211K, L228LIM, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, I293V, E297T, V317A, S322T  
LL5550 LL5550 NRTI NNRTI   V35T, K122A, D123S, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, P243T, V245Q, E248D, D250E, S251E, A272S, K277R, T286A, E291D, V292I, I293V, E297V, V317A  
LL6229 LL6229 NRTI NNRTI M184V  V35T, K49R, V60I, K122E, D123S, A158S, Q174N, D177E, T200A, R211S, I244V, V245Q, E248D, D250E, A272P, L283I, T286TA, E291D, V292I, I293V, S322T, I326V  
LL8420 LL8420 NRTI NNRTI M41L, D67N, T69D, K70R, M184V, T215Y  K20R, V35T, T39DN, E44D, K122E, K173T, Q174K, D177E, I178M, G196E, T200A, E203D, Q207E, H208Y, R211K, V245Q, E248D, D250E, S251H, A272P, Q278H, T286A, A288T, E291D, V292I, I293V, E297A, L301M, I329V  
LL8490 LL8490 NRTI NNRTI   T27S, V35T, E36ED, V60I, A98S, K122E, D123G, I135V, S162A, K173T, Q174R, D177E, T200A, Q207E, V245Q, E248D, A272P, Q278H, T286A, E291D, V292I, I293V, E297A, L301M, K311KT  
LM3929 LM3929 NRTI NNRTI D67N, K70R, M184V, T215F, K219E V108VI, Y181C P4S, T27S, V35T, T39K, K43A, T69TN, V90I, K102Q, V111I, D123E, I142V, S162Y, K173S, D177DE, V179I, T200A, Q207A, R211K, P243PS, V245T, E248D, T286A, E291D, I293V, P294PT  
LM4439 LM4439 NRTI NNRTI K65R, T69~, K219R K103NS, Y181C, G190A K20R, V35T, V60I, S68G, V90I, D121H, K122E, K173T, Q174K, D177E, E194EK, G196GR, T200E, I202V, Q207E, H221Y, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, D324E K46M, I63L 
LM8689 LM8689 NRTI NNRTI M41L, L74LV, M184V, L210W, T215Y  K20R, V35IT, T39DN, E40X, K43KE, K122E, I135IATV, K173A, Q174K, D177E, I178M, I195L, T200A, Q207E, R211K, V245Q, D250E, A272P, Q278H, T286A, A288T, E291D, V292I, I293V, E297A, L301M, D320E, D324E, I329V  
LN0191 LN0191 NRTI NNRTI   V21VI, K22KR, V35T, V60I, K122E, D123GS, S163T, K173T, Q174K, D177E, T200E, I202V, Q207N, R211K, V245K, E248D, D250E, A272P, Q278H, T286A, V292I, I293V  
LN0239 LN0239 NRTI NNRTI   V35T, E36D, K122E, D123DG, I135V, S162A, K173T, Q174K, D177EG, T200A, Q207G, R211K, V245E, E248ED, D250X, S251INT, A272AP, V276VI, T286A, E291D, I293V, K311KR, S322T  
LN0319 LN0319 NRTI NNRTI M41L, D67N, K70R, M184V, T215F, K219Q G190GA V35T, V60I, T69N, L109LI, K122E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, H208HY, R211K, D218E, L228H, K281R, T286TA, E291D, V292I, I293V, P294T, S322A, I326V  
LN0609 LN0609 NRTI NNRTI A62V, V75I, F77L, F116Y, Q151M Y181C, G190A P4T, K20KR, K22R, I31L, V35T, T39K, E40D, T58N, S68G, V90I, V118I, K122E, T165I, K173A, Q174R, D177E, T200A, L205F, Q207E, R211K, F214L, V245Q, E248D, D250E, S251H, A272P, Q278H, K281R, T286A, E291D, V292I, I293V, E297A, L301M, I329V  
LN0911 LN0911 NRTI NNRTI   V35T, E36D, K43KN, E44ED, K101Q, K122E, I142IT, S162A, K173T, Q174A, D177G, T200A, R211K, V245Q, S251N, K277Q, K281R, E291D, V292I, I293V, P294T, E297K, H315HN Q207EIKV 
LN1250 LN1250 NRTI NNRTI   K20R, V35T, E36D, V60I, K122E, D123N, K173A, Q174K, D177E, G196GE, T200A, Q207E, R211RK, P243PS, V245Q, E248DN, S251I, A272P, T286A, E291D, V292IM, I293V, P294T, D320V, S322T, I326V, A327AS T216TIR, K287T 
LN2369 LN2369 NRTI NNRTI M41L, V75M, F77L, M184V, T215Y K103N, P225H V35T, T39LS, I135V, S162A, K173T, Q174K, D177E, T200K, Q207E, R211A, V245Q, E248D, K281R, T286A, E291D, V292I, I293V, P294T, K311R, S322T, I326V  
LN2860 LN2860 NRTI NNRTI M184V  K11KR, V21VI, V35T, T39S, K49R, V60I, D123E, I135L, S162A, E169D, K173T, Q174E, D177E, I178L, T200A, E204EK, Q207E, R211K, V245Q, E248D, A272P, K277R, T286A, I293V, P294T  
LN3579 LN3579 NRTI NNRTI M41L, D67N, T69D, K70R, M184V, T215Y, K219Q A98G, K103N, Y318F V35T, E36D, E40D, V60I, D121H, K122E, I135T, E138Q, S162A, K173T, Q174K, D177E, I195L, G196E, T200A, E203K, Q207E, R211K, F214L, L228H, V245Q, E248D, D250E, K275R, T286A, E291D, V292I, I293V, P294T, E297EK, S322T, L325I, I326V  
LN3979 LN3979 NRTI NNRTI   G15GE, V35T, E36D, D121Y, K122E, I135V, S162A, E169EK, K173ADEG, Q174K, D177E, T200A, Q207E, R211K, P243A, V245Q, A272P, K275R, K277R, Q278N, T286A, E291D, V292I, I293V, P294PQ, E297A, V317A, S322T  
LN4321 LN4321 NRTI NNRTI A62V, K65R, V75I, F77L, Y115F, F116Y, Q151M, M184V, K219E Y181C K20R, V35T, S68G, T69I, I135V, S162A, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, F214L, V245E, S251H, T286A, E291D, V292I, I293V, P294T, E297K, K311R, S322T, I326V  
LN4711 LN4711 NRTI NNRTI   V35T, V90I, K104R, K122E, D123N, K173A, Q174K, D177E, I178M, T200A, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, L295M, D324E, I329V  
LN5329 LN5329 NRTI NNRTI M184V  E6K, K11T, V35T, K64KR, D121H, K122E, I135T, I142V, S162Y, F171Y, K173S, D177E, V179I, T200A, I202V, Q207DN, R211K, F214L, V245Q, T286A, E291D, I293V, P294T, E312D, I326V  
LN6209 LN6209 NRTI NNRTI K70R  V35T, V60I, K64R, D121H, K122E, D123S, I135V, F171Y, K173AV, Q174K, D177E, I178L, T200E, Q207K, R211Q, V245Q, K275Q, K277R, T286A, E291D, V292I, I293V, P294I, E297K, E312G  
LN6370 LN6370 NRTI NNRTI  V179E V35T, E36D, T39K, V60I, K104KR, D121Y, K122E, I135R, E169D, K173A, Q174K, D177E, I178L, T200A, I202V, Q207E, R211K, F214L, V245Q, E248DN, D250DE, S251SIN, A272P, K277R, E291D, V292I, I293V  
LN8580 LN8580 NRTI NNRTI M41L, M184V, T215F A98G V35T, E36D, K49R, D123E, I135T, A158S, S162A, K173A, Q174K, D177E, T200A, E203V, Q207E, R211K, V245E, T286A, E291D, I293V, P294T, S322T  
LN9690 LN9690 NRTI NNRTI D67G, K70R, M184V, K219E K103N, Y181C K20R, V35T, V60I, S68G, V90I, A98S, K122E, D123S, I135T, Q174KR, D177E, T200A, Q207E, R211K, L228R, V245E, E248D, D250E, S251D, A272P, K275R, K277T, T286A, E291D, V292I, I293V, E297A, Q334H  
OU1919 OU1919 NRTI NNRTI   K22KN, V35M, K122E, K173A, Q174R, D177E, G196E, T200A, Q207D, R211K, V245Q, E248D, D250E, A272Q, E291D, I293V, D324E, I329V  
OU8939 OU8939 NRTI NNRTI M41L, D67N, K70R, V75M, M184V, T215F, K219Q K101E P9PQ, V35T, T39A, V60I, T69N, V118I, K122E, D123S, I135R, Q174E, D177E, I178M, T200A, E204K, Q207E, F214L, V245Q, E248N, D250E, A272P, E291D, V292I, I293V, P294T, K311KT, D324E, I329V  
OU9780 OU9780 NRTI NNRTI   P4S, E6ED, T27S, V35T, E36D, S68G, D123E, I135IV, S162A, K173I, Q174K, D177E, I178L, T200A, Q207E, R211K, P243H, V245E, E248D, T286A, E291D, V292I, I293V, S322A, I326V  
PJ0771 PJ0771 NRTI NNRTI M184V K101E, G190A K11A, V35T, E36A, T39K, K43E, V60VI, K122KE, D123N, E138A, I142V, S162T, F171Y, K173T, Q174K, D177E, I178M, T200A, Q207K, R211N, V245E, D250E, S251H, K281R, T286A, E291D, V292I, I293V, P294T, P313S, V317EG, S322T, I326V  
PJ1681 PJ1681 NRTI NNRTI D67G, K70R, M184V, T215F, K219Q Y188L K20R, V35T, K46Q, S68G, S105T, K122E, D123NS, I135V, S163T, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, H221Y, E224D, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293IV, G333D, Q334N  
PJ2149 PJ2149 NRTI NNRTI M41L, D67N, T69D, K70R, V75M, M184V, L210W, T215F, K219Q K101E, Y181C, G190A K20R, K32KR, V35T, K43N, V60I, V111I, V118I, K122E, I142V, S162D, Q174K, D177E, I178M, V179M, V189I, T200A, E203D, Q207DE, H208Y, R211K, D218E, L228H, P243T, V245Q, E248D, T286A, E291D, V292I, I293V, E297A  
PJ2562 PJ2562 NRTI NNRTI K65R, M184V, K219E K101H, Y181C, G190A K20R, V35T, E36D, V60I, S68K, I135V, K173T, Q174R, D177E, I178M, T200A, Q207E, R211K, P243A, V245E, K277R, T286A, E291D, V292I, I293V, P294T, S322T, I326V  
PJ4671 PJ4671 NRTI NNRTI D67N, M184V, T215Y, K219E Y188L I2V, P4PS, E6EK, V35T, T39K, E40D, V60I, K104R, V118I, K122E, D123N, T165I, K173T, Q174K, D177E, V189I, T200A, E203K, Q207E, H208Y, R211K, F214L, K223E, V245Q, E248N, D250E, S251N, A272P, K275R, Q278N, R284K, T286A, E291D, V292I, I293V, E297K, I329V  
PJ4782 PJ4782 NRTI NNRTI M184V, T215Y K103N, M230L K32R, V35T, V60I, V118C, K122E, D123S, S162A, Q174E, D177E, T200A, Q207E, D218E, V245Q, A272P, L283I, T286A, E291D, V292I, I293V, P294T, S322T  
PJ5683 PJ5683 NRTI NNRTI M41L, D67G, T69D, K70R, M184V, T215F, K219Q Y181C I31L, V35T, T39A, K49R, V60I, K173T, Q174R, D177E, I178M, T200A, Q207E, R211K, L228R, V245Q, E248D, D250E, S251D, A272P, K277R, T286A, E291D, V292I, I293V, D324E  
PJ6749 PJ6749 NRTI NNRTI M41L, M184V, L210W, T215Y A98G, Y181C, G190A V21I, V35T, E44D, T69N, W88C, V111I, V118I, K122E, K173A, Q174K, D177E, T200A, E203K, Q207D, H208Y, R211RK, K223E, L228R, P243PS, V245Q, E248D, A272S, T286A, A288S, V292I, I293V, I329V  
PJ6799 PJ6799 NRTI NNRTI M41L, D67DG, T69AD, K70R, M184MV, L210LW K101E, Y181C, G190A E28K, V35T, T39L, V60I, K104R, V118VI, D121Y, K122E, I135IT, K173T, Q174R, D177E, I178M, T200A, Q207E, R211K, T215X, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292VI, I293V, I329V  
PJ7081 PJ7081 NRTI NNRTI M41L, D67N, K70R, V75VIM, M184V, T215FY, K219EQ K101E, G190A E28K, V35T, T39M, V60I, K173A, Q174K, T200A, I202V, E203EK, Q207E, V245Q, E248D, D250E, S251N, A272P, K281R, T286TA, E291D, V292I, I293V, I329V  
PJ8320 PJ8320 NRTI NNRTI   K20R, V35T, V60I, K104KR, K122E, D123S, K173KT, D177E, I178IL, T200A, Q207E, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, D324E  
PJ8430 PJ8430 NRTI NNRTI M41L, D67DN, K70KR, V75VIM, M184V, T215Y, K219KE V106A, F227L S3C, I5V, V8I, V21I, V35T, V60I, D121H, K122E, I135T, S163T, Q174A, D177E, T200A, I202V, E203A, Q207D, L228R, V245Q, E248D, D250E, S251N, A272AP, T286A, E291D, V292I, I293V, I329V  
PJ8953 PJ8953 NRTI NNRTI M41L, D67DG, T69S_EA, M184V, T215Y A98G, K103N V35T, E44ED, V60I, I94IL, V118VI, K122E, D123S, I132V, K173T, Q174K, D177E, I178L, T200A, Q207N, L210LS, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, E297EK  
PJ9169 PJ9169 NRTI NNRTI   V35T, T39E, E40D, K122E, D123S, K173T, D177E, I178IM, T200A, Q207E, R211K, V245Q, D250E, A272P, K277R, T286TA, V292I, I293V, P294T  
PJ9522 PJ9522 NRTI NNRTI  A98AG, K103KN K20R, V35T, T39K, E40D, V60I, D123E, I142V, K173T, Q174K, D177E, I178M, T200A, Q207D, R211K, L228R, V245E, E248D, D250DE, S251D, T286A, E291D, V292I, I293V, P294A, S322T, I326V  
PJ9581 PJ9581 NRTI NNRTI K65R, F116Y, Q151M, M184V K103N, Y181C K20R, E28D, K32KQ, V35K, E36D, T39A, S68G, K101R, D123E, I135T, S162A, T165I, E169D, K173T, Q174K, D177E, G196E, T200A, Q207E, F214L, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V  
PJ9611 PJ9611 NRTI NNRTI M41L, M184V, T215Y A98G, K103KN, V108VI V35T, V60I, L109LI, D121HY, K122E, I135T, K173T, Q174R, D177E, T200A, I202V, Q207D, R211K, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, I329V  
PJ9681 PJ9681 NRTI NNRTI A62V, V75I, F77L, Y115F, F116Y, Q151M, M184V, K219E K103N, V108I, K238T P14A, D17DE, V35T, E36D, E40K, K43Q, K46Q, K49R, T58N, S68G, K122E, D123N, I135IV, S162T, K173T, Q174K, D177E, I178IM, T200A, E203EK, Q207E, R211K, V245E, A272P, Q278N, L283I, E291D, V292I, I293V, P294A, S322T, D324E I244IT 
PJ9959 PJ9959 NRTI NNRTI M41L, D67G, T69D, K70R, M184V, L210W, T215F Y181I I31L, V35T, E36A, T39A, K43E, V118VI, K122KE, S162A, K173I, Q174K, D177E, I178M, V179I, G196E, T200A, E203V, Q207E, V245E, T286A, E291D, V292I, I293V, P294T, S322T