<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Sunpath (2013)
Title High rate of K65R for antiretroviral therapy-naive patients with subtype C HIV infection failing a tenofovir-containing first-line regimen.
Citation AIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 38
NumPts 38
Subtype C


Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
CAS014 CAS014 TDF, D4T, AZT, 3TC NVP, EFV D67DN, M184V K101E, V106M, G190A V35T, T39E, S48T, V60I, K122E, D123S, K173T, D177E, T200A, Q207A, F214L, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
CAS031 CAS031 TDF, 3TC NVP K65R, Y115F V179D, Y181C P4S, V35T, E36A, T39E, S48T, V60I, K122E, D123S, I142V, T165K, K173A, Q174R, D177E, I178L, T200A, Q207A, R211K, V245Q, K277R, T286A, E291D, V292I, I293V  
CAS033 CAS033 D4T, 3TC EFV M41L, K65R, L74V, V75T, Y115F G190E K20R, V35T, T39E, S48T, V60I, S68G, D121H, K122E, I135V, I142V, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, H221Y, V245Q, A272P, K275R, V276T, E291D, V292I, I293V, I329V  
CAS035 CAS035 TDF, 3TC EFV K65R, L74V, Y115F G190E S3SC, V35T, T39E, S48T, V60I, K122E, D123S, K173A, D177E, I178M, T200A, Q207E, V245Q, D250E, S251D, A272P, K275Q, K277R, T286A, E291D, V292I, I293V, D324E  
CAS036 CAS036 D4T, 3TC, TDF EFV M41L, L74V, M184V V106M, V179D, Y188C, G190GE V35T, E36A, T39E, S48T, V60I, K103R, K122E, K173A, D177E, Q207E, R211K, F214L, V245E, K277R, T286A, E291D, V292I, I293V, D324E  
CAS039 CAS039 D4T, 3TC, TDF EFV K65R, K70R, V75I, Y115F V106M, Y188C V35T, T39E, G45E, S48T, V60I, K122E, D123S, K173A, D177E, T200A, Q207E, R211K, V245Q, Y271H, A272S, K277R, T286A, E291D, V292I, I293V, H315Y  
CAS042 CAS042 TDF, 3TC, D4T EFV M184V V106M, Y188C P4S, V35T, E36A, T39E, S48T, V60I, V118I, K122E, D123S, E138A, T165I, K173A, Q174K, N175H, D177E, I178L, T200A, Q207E, R211K, F214L, V245Q, A272P, K275Q, K277R, A288S, E291D, I293V, E297K, V314I  
CAS043 CAS043 TDF, 3TC EFV D67DN, M184I V108I, V179E, Y181C K20R, V35T, E36A, T39K, K43E, S48T, V60I, V90VI, K102Q, K103R, K122E, D123N, Q174K, D177E, V189VI, T200A, R211K, F214L, H221HY, V245Q, A272P, A288S, E291D, V292I, I293V  
CAS044 CAS044 TDF, 3TC EFV K65R V106M, Y188C V35T, E36A, T39E, E44D, S48T, K122E, D123S, I135T, S162C, K173A, Q174K, T200A, Q207E, R211K, F214L, V245Q, A272P, K281R, T286A, E291D, V292I, I293V  
CAS045 CAS045 TDF, 3TC EFV K65R V106M, V179D, Y181C K20R, V35T, E36A, T39E, S48T, V60I, K122E, D123S, I135T, K173A, Q174K, D177E, T200V, Q207AT, R211K, F214L, V245Q, E248D, A272P, E291D, V292I, I293V, V314I, V317A  
CAS048 CAS048 TDF, 3TC EFV K65R V106M, Y188C V8I, V35T, E36A, T39D, V60I, K122P, D123E, I142R, K173T, Q174K, D177E, I178L, G196E, T200A, Q207D, R211K, V245Q, D250E, A272P, K277R, E291D, V292I, I293V, K311R  
CAS052 CAS052 TDF, 3TC EFV K65R V106M, Y188L V35T, T39E, S48T, V60I, S68N, K122E, D123G, K173M, D177E, T200A, Q207A, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, D324E  
CAS054 CAS054 TDF, 3TC EFV K65R, Y115F K103N, Y181C, G190S V35I, T39E, S48T, K122E, D123N, K173A, D177E, G196K, T200E, I202V, E204K, Q207D, R211K, H221Y, V245Q, E248D, D250E, A272P, R284K, E291D, I329L  
CAS056 CAS056 TDF, 3TC EFV K65R K103N, V108I, Y181C, G190A K20R, V35T, E36V, T39E, S48T, V60I, K122E, D123N, K173A, Q174K, D177E, V179A, T200A, I202V, Q207E, V245Q, K275Q, T286A, E291D, V292I, I293V  
CAS057 CAS057 TDF, 3TC EFV D67G K101E, V106M E6K, V35T, T39E, S48T, V60I, T69N, K122E, D123S, I135V, I142V, S162C, K173A, Q174R, D177E, I178L, T200A, Q207E, R211K, H221Y, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, D324E  
CAS061 CAS061 D4T, 3TC EFV  V106M, F227L K20R, V35T, E36A, T39E, S48T, V60I, K122E, E138A, K173A, Q174K, D177E, I178L, G196E, T200A, K201R, E204K, Q207D, R211K, F214L, V245K, A272P, K275R, Q278E, T286A, E291D, V292I, I293V, E328D, I329V  
CAS063 CAS063 3TC, D4T NVP M184V A98AG, K103RST, G190A K20R, K32Q, V35T, E36A, T39K, K43E, S48T, K122E, K173A, Q174K, D177E, T200A, R211K, V245Q, I257V, A272P, K275R, E291D, V292I, I293V  
CAS066 CAS066 TDF, 3TC EFV K65R G190E V35T, T39K, S48T, V60I, K122E, D123S, K173A, Q174K, G196E, T200A, Q207K, R211A, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
CAS068 CAS068 TDF, 3TC EFV D67N, K70E, M184V A98G, K103N, V106M K20R, V35T, T39E, S48T, V60I, K122E, T165I, K173A, Q174K, D177E, T200A, I202V, E203K, Q207E, R211RK, V245Q, A272P, K275Q, Q278N, E291D, V292I, I293V  
CAS069 CAS069 TDF, 3TC EFV M184I  V35T, T39E, S48T, V60I, K173I, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, T286A, E291D, V292I, I293V  
CAS070 CAS070 TDF, 3TC EFV K65R A98G, V179D, Y181C, G190A V21I, T27S, V35T, T39E, S48T, V60I, K122E, K173A, D177E, T200A, Q207E, R211K, V245K, D250E, S251D, A272P, E291D, V292I, I293V  
CAS071 CAS071 TDF, 3TC EFV K65R V106M, Y181C, F227L K20R, V35T, T39E, S48T, V60I, K122E, D123S, T165V, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, F214L, H221Y, V245Q, A272P, E291D, V292I, I293V, D324DE  
CAS072 CAS072 TDF, 3TC EFV L74LI, M184V K103N, V106M V35T, T39E, S48T, V60I, K102R, K122E, K173A, Q174K, D177E, T200A, Q207A, R211K, F214L, V245Q, A272P, E291D, V292I, I293V, V317A  
CAS073 CAS073 TDF, 3TC EFV K65R, Y115F, M184V V106M, V179D K20R, V35T, T39K, K43E, S48T, V60I, S68N, K103R, K122E, T165I, K173A, Q174R, D177E, I178L, T200A, Q207T, R211K, F214L, V245Q, A272P, K277R, E291D, V292I, I293V, S322T  
CAS074 CAS074 TDF, 3TC EFV M184V V106M, G190A, F227L P4S, V8I, V35T, T39D, S48T, V60I, I142V, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, V245Q, A272P, E291D, V292I, I293V, K311R  
CAS077 CAS077 TDF, 3TC EFV K65R K103N, V106M V35T, T39E, S48T, V60I, K122E, D123G, K173A, Q174K, D177E, T200A, Q207D, R211K, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, D324E  
CAS078 CAS078 TDF, 3TC EFV M184V K103N, V106M V35T, T39E, S48T, V60I, K122E, D123G, K173T, D177E, I178L, T200A, Q207R, R211K, V245E, A272P, E291D, V292I, I293V  
CAS079 CAS079 TDF, 3TC EFV K65R, Y115F G190E V21I, V35T, T39E, V60I, T69N, K122E, I135V, K173T, D177E, T200A, Q207N, V245E, A272S, T286A, E291D, V292I, I293V, D324E  
CAS080 CAS080 TDF, 3TC EFV K65R Y181C P4S, V35T, T39E, S48T, V60I, V118I, K122E, D123S, K173A, Q174K, G196E, T200A, Q207A, R211K, F214L, H221Y, V245Q, E291D, V292I, I293V  
CAS081 CAS081 TDF, 3TC EFV K65R V106M, Y188L V35T, T39E, S48T, V60I, K122E, D123S, K173T, Q174K, G196E, T200A, Q207E, R211K, V245K, A272P, L279I, E291D, V292I, I293V, I329L  
CAS082 CAS082 TDF, 3TC EFV M184V K103N, P225H P4T, K20R, V35T, E36A, T39K, K43E, S48T, V60I, V118I, K122E, I135L, K166R, K173A, D177E, T200A, Q207E, R211K, F214L, V245Q, A272P, K275R, K277R, T286A, E291D, V292I, I293V, P294S, V317A, D324E  
CAS084 CAS084 TDF, 3TC EFV K65R, K70T V106M, Y188N P4S, V35T, E36A, T39E, S48T, E53D, S68G, K122E, D123S, S162A, T165I, K173A, Q174K, D177E, T200A, I202V, Q207E, V245Q, A272P, K277R, Q278N, T286A, E291D, V292I, I293V  
CAS086 CAS086 TDF, 3TC EFV K65R K103N, V106M P4T, K20R, V35T, E36T, T39E, S48T, V60I, V118I, K122E, D123G, T165I, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, F214L, V245Q, A272P, T286V, E291D, V292I, I293V  
CAS090 CAS090 TDF, 3TC EFV K65R L100I, K103N, V106M V35T, T39E, E40Q, S48T, K122E, D123N, I135M, T139A, S162C, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, V245Q, T286A, E291D, V292I, I293V, E297A  
CAS092 CAS092 TDF, 3TC EFV K65R K101E, V106M, F227L V35T, T39E, S48T, V60I, K122E, I135K, K173A, Q174K, D177E, I178L, G196E, T200A, E204K, Q207E, R211K, V245E, D250E, A272P, T286A, E291D, V292I, I293V  
CAS096 CAS096 TDF, 3TC EFV K65R, M184V L100I, K103S, Y318F K20R, V35R, T39D, S48T, K122E, D123S, I135T, K173T, T200A, Q207E, F214L, V245K, A272P, T286A, E291D, V292I  
CAS107 CAS107 TDF, 3TC EFV K65R, D67N, V75I, Y115F, K219E V106A, G190E V35T, E36A, T39E, S48T, V60I, K102R, K103R, K122E, D123S, K173A, Q174K, D177E, I178M, T200A, Q207A, R211K, V245K, A272P, V276T, K277R, T286V, V292I, I293V  
CAS109 CAS109 TDF, 3TC EFV K65R, T69~ K101E, E138K, G190E V35T, E36A, T39E, S48T, V90I, K122E, K173T, D177E, T200A, Q207E, V245K, A272P, R284K, T286A, E291D, V292I, I293V