<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Li (2013)
Title Subtype CRF01_AE dominate the sexually transmitted human immunodeficiency virus type 1 epidemic in Guangxi, China.
Citation J Med Virol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 211
NumPts 211
Subtype CRF01_AE, C, B


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Page 1   from Isolate 1 to Isolate 100 from Total 211 Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
2003 2003 None None   E6D, K11T, V35T, T39K, K43E, K102M, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, Q207R, R211S, K238R, V245E, K249R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, S379G, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
2011 2011 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, S162C, K173I, Q174K, D177E, T200I, Q207S, R211S, K238R, V245E, K249R, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, S468T, D471E, Q480H, L491S, K512R, E514ED, L517V, S519N, Q524E, A534S, A554S  
2013 2013 None None   E6D, V35T, T39K, K43E, K122E, D123S, I135T, K166R, K173I, Q174K, D177E, T200I, Q207A, R211S, K238R, I244V, V245E, A272P, K277R, T286A, E291D, V292I, I293V, E312T, H315N, I326V, I329V, Q334E, K347R, M357R, R358G, G359S, K366R, A371V, T386TI, K390R, K395R, A400T, V435G, V466A, V467I, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, K530R, A534S, A554S  
2015 2015 None None   E6D, K11T, V35T, T39E, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, I178IM, T200I, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, P321S, D324E, I329V, G335D, M357K, G359S, K366R, A371V, T386I, A400T, T403M, E432D, N447S, Q464K, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554Q  
2019 2019 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, I274V, T286A, E291D, V292I, I293V, E312T, I329V, G335D, M357K, G359S, K366R, A371V, S379G, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
2020 2020 None None M41L  E28K, K32E, V35T, E36A, T39D, S48T, V60I, D121Y, K122E, V245Q, E248V, K249Q, A272P, K277R, T286A, E291D, V292I, I293V, G335D, T338S, R356K, G359T, T377M, A400T, E404D, V435G, A437V, N447S, L452I, Q464K, D471E, Q480H, H483C, L491S, S519N, K530R, A534S, A554S  
2028 2028 None None   E6D, K11T, V35T, T39E, V106I, K122E, D123S, S162C, K173I, Q174K, D177E, T200A, Q207S, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, K347KR, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D460N, D471E, Q480H, H483HY, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2029 2029 None None   E6D, K11S, V35T, T39K, K43E, K49R, K122E, D123S, I135T, K173I, Q174K, D177E, I178V, Q207S, R211S, K238R, V245E, K249R, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, M357K, G359S, K366R, A371V, K390R, K395R, T397I, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
2030 2030 None None  V179D E6D, K11ST, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, Q207S, R211S, V245E, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, M357K, G359S, K366R, A371V, K390R, T397I, A400T, T403M, E404D, E432D, N447S, D471E, Q480H, H483HY, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
2040 2040 None None   V35T, E36A, T39D, S48T, V60I, D86DE, E169ED, D177N, V245Q, A272P, V276T, K277R, T286A, E291D, V292I, I293V, V317A, G335D, R356K, G359T, T377M, K390R, A400T, E404D, E432D, V435A, L452I, Q464K, D471E, H483C, L484I, L491P, L517I, S519N, A534S, A554S  
2041 2041 None None   E6D, K11T, V35T, T39E, K122E, D123S, S162C, K173I, Q174K, D177E, I202IV, Q207N, R211S, K238R, V245E, A272P, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T377Q, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2044 2044 None None   E6D, K11T, V35T, T39K, K43E, V60I, K122E, D123S, I142V, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E, K249R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2046 2046 None None   E6D, K11T, V35T, T39K, K43E, V60I, K122E, D123S, I142V, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E, K249R, T286A, E291D, V292I, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2049 2049 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, S162C, K173R, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E297V, E312T, V317T, I326V, I329V, G335D, M357K, G359S, K366KR, A371V, T377M, K390R, A400T, T403M, N447S, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
2050 2050 None None   E6D, K11T, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, Q207DN, R211S, K238R, V245E, T286A, E291D, V292I, P294Q, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
2053 2053 None None   E6D, K11T, K20R, V35T, T39K, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, K281R, T286A, E291D, V292I, I293V, E297K, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376V, K390R, K395R, A400T, T403M, E432D, N447S, Q464K, V467I, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, K550R, A554S  
2055 2055 None None   E6D, K11T, V21I, V35T, K122E, D123S, I135R, S162C, K173I, Q174K, D177E, I178M, Q207S, R211S, K238R, V245E, V276I, K281R, L283I, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T386I, A400T, T403M, E432D, N447S, S468H, T470S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
2059 2059 None None   E6D, K11T, V35T, T39K, K122E, D123S, S162C, K173M, Q174K, D177E, I178M, Q207S, R211S, V245E, E291D, I293V, E297K, K311N, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, D471E, L491S, K512R, E514D, L517I, S519N, Q524E, A534S, A554S  
2063 2063 None None  V179D E6K, K20R, V35T, E36A, T39D, S48T, E53D, V60I, T69S, T107S, K122E, I135V, S162Y, Q207E, R211K, V245Q, A272P, K277R, V292I, I293V, P313T, V317A, D324E, G335D, R356K, G359AT, K366KR, T377M, T386I, K390R, A400T, E404D, E432D, V435A, A437V, Q464R, V466I, V467VI, H483Y, L484I, L491S, S519N, K530R, A534S, A554Q  
2066 2066 None None   E6D, V35K, T39E, S68G, K122E, D123N, S162C, K173IT, Q174K, D177E, I178M, Q207S, R211S, K238R, V245E, A272V, T286TA, E291D, V292I, I293V, E298EK, E312T, I326V, I329V, G335D, E344D, K350R, M357K, G359S, K366R, A371L, K390R, A400T, T403R, E432D, N447S, D471E, Q480H, L491P, L517V, S519N, Q524E, V531I, A534S, Q547K, A554E, K558R  
2067 2067 None None   V35T, T39D, S48T, V60I, V245Q, A272P, V276I, K277R, E291D, V292I, I293V, V317A, D324E, G335D, R356K, G359T, A371V, T377M, K390R, A400T, E404D, E432D, V435A, A437V, L452I, Q464K, D471E, H483C, L484I, L491S, S519N, K530R, A534S, A554S  
2069 2069 None None   E6D, K11T, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, Q207R, R211S, V245E, A272P, I274V, T286A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376S, T377M, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, K530R, A534S, A554S  
2070 2070 None None   E6D, K11KT, V35T, T39R, K43E, K122E, D123S, S162C, K173R, Q174K, D177E, I178IM, T200I, Q207A, R211S, K238R, V245E, T286A, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
2075 2075 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123N, K173I, Q174K, D177E, I178M, T200I, E204K, Q207A, R211S, K238R, V245E, A272P, E291D, V292I, I293V, E312N, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K385R, K390R, K395R, A400T, T403M, E432D, N447S, V467I, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2077 2077 None None   E6D, V8I, K11T, V35T, T39K, K43E, K122E, D123S, K173L, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, E291D, V292I, I293V, K311R, E312N, I329V, G335D, M357K, G359S, K366R, A371V, I375V, A376S, T386I, K390R, K395R, A400T, T403M, E432D, N447S, T470S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2080 2080 None None   E6D, K11T, E28K, K32E, V35T, T39K, K43R, K122E, D123S, S162C, K173IV, Q174K, D177E, I178M, V179I, T200A, Q207K, R211S, K238R, V245E, T286A, A288S, I293V, E297K, K311Q, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D460DN, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
2087 2087 None None   K20R, V35T, E36A, T39E, S48T, E53D, V60I, T69S, I135V, S162SC, Q207E, R211K, V245Q, E248N, A272P, K275R, K277R, T286A, E291D, V292I, I293V, A304E, V317A, D324E, G335D, R356K, G359T, T377M, T386I, K390KR, A400T, E404D, E432D, V435A, A437V, L452I, Q464K, V466I, H483Y, L484I, L491S, S519N, K527R, K530R, V531I, A534S, A554N  
2088 2088 None None   E6D, K11T, V35I, T39N, K122E, D123S, I135M, S162C, K173I, Q174K, D177E, I178IM, Q207N, R211S, E224EK, K238R, V245E, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376V, V381VI, K390R, A400T, T403M, E432D, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
2089 2089 None None   E28K, K32E, V35T, E36A, T39D, S48T, V60I, K104R, D121Y, K122E, I135M, V245Q, E248V, K249Q, A272P, K277R, T286A, E291D, V292I, I293V, I309V, T338S, R356K, G359T, V365I, T377M, I382L, K390R, A400T, E404D, E432D, V435A, A437V, L452I, Q464K, D471E, Q480H, H483C, L491S, S519N, K530R, A534S, A554S  
2091 2091 None None   E6D, K20R, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, I178IM, Q207K, R211S, K238R, V245E, E291D, V292I, I293V, E300ED, E312N, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2093 2093 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207DN, R211RS, K238R, V245E, T286A, E291D, V292I, I293V, K311R, E312N, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2095 2095 None None   E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207K, R211S, K238R, V245E, K249R, T286A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, I382M, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
2102 2102 None None   E6D, V35T, T39N, K122E, D123S, S162C, K173I, Q174K, D177E, Q207N, R211S, V245E, A272P, I274V, T286A, E291D, V292I, I293V, E312NT, I326V, I329V, G335D, P345T, M357K, G359S, K366R, A371V, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2105 2105 None None  V179D K20R, V35T, E36A, T39E, S48T, E53D, V60I, T107S, D123E, I135L, S162C, D177N, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, V317A, D324E, Q334H, G335E, R356K, G359T, T377M, T386I, K390R, A400T, E404D, E432D, V435A, A437V, L452I, Q464K, H483Y, L484I, L491S, S519N, K530R, A534S, A554N  
2106 2106 None None  V179D K20R, V35T, E36A, T39E, S48T, E53D, V60I, T69S, T107S, D123E, I135V, S162C, D177N, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, A304AE, V317A, D324E, I326M, Q334HN, G335D, R356K, G359T, T377M, T386I, K390R, A400T, E404D, E432D, V435A, A437V, L452I, Q464K, H483Y, L484I, L491S, S519N, K530R, A534S, V548I, A554N  
2111 2111 None None   E6D, K11T, K20KR, V35T, T39K, K43E, V60VI, K122E, D123S, K173I, Q174K, D177E, I178IM, T200I, Q207A, R211S, V245E, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390R, K395KR, A400T, T403M, E404D, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2113 2113 None None  V179E E6D, V35T, T39K, K43E, K122E, D123S, I135R, R211K, F214L, V245A, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K388R, K390R, A400T, D460N, R461K, H483Y, L491S, S519N, K527N, K530R, A554S  
2115 2115 None None   E6D, K11T, V35T, T39K, V90I, D123N, R172K, K173I, Q174K, D177E, I178M, T200M, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, H483Q, L491T, K512R, L517V, S519N, Q524E, A534S, A554S  
2117 2117 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, Q207N, R211S, K238R, V245E, K249R, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, L452I, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
2121 2121 None None   E6N, V8I, V35T, E36A, T39D, S48T, E53D, V60I, T69S, I132V, I135V, S162C, Q207E, R211K, V245Q, A272P, V276I, K277R, T286A, E291D, V292I, I293V, V317A, D324E, G335D, R356K, G359T, A376S, T377M, K390R, E396D, A400T, E404D, E432D, V435A, A437V, D460N, Q464K, V466I, H483Y, L484I, L491S, S519N, K530R, A534S, A554N  
2127 2127 None None   K20R, V35T, E36A, T39D, S48T, E53D, V60I, T69S, I135V, S162C, Q207E, R211K, V245K, A272P, K277R, V292I, I293V, H315Q, V317A, D324E, G335D, R356K, G359T, T377M, T386I, K390R, A400T, E404D, E432D, V435A, A437V, L452I, Q464K, V466I, V467I, H483Y, L484I, L491S, S519N, K530R, A534S, Q547E, A554N  
2131 2131 None None   E6D, V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, K238R, I244V, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, Q334E, G335D, M357K, R358S, G359S, K366R, A371V, T377K, K390R, K395R, A400T, T403M, V435G, R448K, V466T, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
2135 2135 None None   K20R, V35T, T39N, S48T, V60I, V245Q, A272P, V276I, K277R, E291D, V292I, I293V, H315Q, V317A, G335D, R356K, G359T, A376S, T377M, K390R, A400T, E404D, E432D, V435A, A437V, L452M, Q464K, D471E, H483C, L484I, L491S, S519N, K530R, A534S, A554S  
2141 2141 None None   K20R, V35T, T39N, S48T, E53D, V60I, T69S, I135V, I142IV, S162C, Q207E, R211K, V245E, A272P, L283I, E291D, V292I, I293V, H315Q, V317A, D324E, G335D, R356K, G359T, K366R, T377M, T386I, A400T, E404D, E432D, V435A, A437V, L452LI, Q464K, H483Y, L484I, L491S, L517I, S519N, K527N, K530R, A534S, A554S  
2142 2142 None None   E6D, K11T, V35T, T39K, K122E, D123N, I135T, S162C, K173I, Q174K, D177E, I178M, Q207N, R211K, K238R, V245E, A272P, K275KQ, K277KR, T286A, E291D, V292I, E312T, I326V, I329V, G335D, K350R, M357K, G359S, K366R, A371V, K390R, A400T, E432D, V466VA, D471E, Q480H, H483HY, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
2150 2150 None None   K20R, V35T, E36A, T39D, S48T, E53D, V60I, T69S, I135V, S162C, Q207E, R211K, V245K, A272P, K277R, V292I, I293V, H315Q, V317A, D324E, G335D, P345Q, F346Y, R356K, G359T, T377M, T386I, K390R, A400T, E404D, E432D, V435A, A437V, L452I, Q464K, V466I, V467I, H483Y, L484I, L491S, S519N, K530R, A534S, Q547E, A554N  
2152 2152 None None   E6D, K11T, V35T, E36A, T39E, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, V245E, E291D, V292I, I293V, E312T, I326V, I329V, G335D, K347R, R356K, M357K, G359S, K366R, A371V, K390R, K395R, A400T, E432D, N447S, D460N, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, I526V, A534S, A554S  
2157 2157 None None   E6D, K11T, V35T, T39E, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207S, R211S, K238R, V245E, A272P, V276I, T286A, V292VI, I293V, E312N, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A400T, T403M, E432D, V435I, N447S, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, K527R, A534S, A554S A360ADNT 
2161 2161 None None   E6D, K11T, V35T, K122E, D123S, I135IT, S162C, K173I, Q174K, D177E, I178M, Q207R, R211S, K238R, V245AE, T286A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, A355G, M357K, G359S, T369A, A371V, T377Q, K390R, A400T, T403M, E432D, N447S, R461K, D471E, Q480Y, I482V, H483Y, L491S, A502V, K512R, S515A, L517V, S519N, Q524E, A534S, Q547K, A554S  
2167 2167 None None   E6D, V35T, T39N, K122E, D123N, S162C, K173R, Q174K, D177E, Q207K, R211S, K238R, V245E, E248D, A272P, K275R, T286A, V292I, I293V, E297G, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, V435A, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, V548A, I556V  
2168 2168 None None   E6D, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, T200I, Q207A, R211S, V245E, A272P, V276I, T286A, E291D, I293V, E312T, I326V, I329V, G335D, M357K, R358S, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
2175 2175 None None   E6D, V35T, T39D, K122E, D123N, I135R, S162C, K173I, Q174K, D177E, I178M, Q207S, R211S, K238R, V245E, I274V, T286A, E291D, V292I, I293V, E312T, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, V435I, N447S, T470N, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, Q547K, A554E, K558R  
2182 2182 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, T200TI, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, A376AS, T377TIM, V381VI, K390KR, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S, K558R  
2185 2185 None None   V35T, E36A, T39D, S48T, V60I, D121H, K122E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, V317A, G335D, R356K, G359T, T377M, K390R, A400T, E404D, E432D, V435A, L452I, Q464K, D471E, H483C, L484I, L491S, S519N, K530R, A534S, A554S  
2186 2186 None None   E6D, K11T, V35T, T39K, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, Q207G, R211S, K238R, V245E, A272G, T286A, E291D, V292I, I293V, E297K, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376AV, K390R, K395R, A400T, T403M, E432D, V435A, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2190 2190 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, T200I, Q207A, R211S, K238KR, V245E, T286A, E291D, V292I, I293V, E312T, I326M, I329V, G335D, M357K, G359S, K366R, A371V, K385R, K390R, K395R, A400T, T403M, E432D, R463K, D471E, Q480H, H483Q, L491S, L517V, S519N, Q524E, A534S, A554S  
2192 2192 None None   E6D, T7TAIV, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E, I274V, T286A, E291D, V292I, I293V, E312N, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2201 2201 None None   E6D, T7V, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, I244V, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, A355T, M357K, G359S, K366R, A371V, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2203 2203 None None   E6D, K11T, V35T, T39K, K43E, V60I, K122E, D123S, I142V, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376V, T386A, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2206 2206 None None   V35T, T39N, S48T, E53D, V60I, T69S, D123E, I135T, S162C, Q207E, R211K, V245Q, A272P, K277R, V292I, I293V, V317T, D324E, G335D, R356K, G359AT, T377M, T386V, K390R, A400T, E404D, E432D, V435A, A437V, L452I, Q464K, H483Y, L484I, L491S, S519N, K530R, A534S, A554N  
2209 2209 None None   E6D, K11T, K20R, V35T, T39K, K43E, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E312NT, I329V, G335D, M357K, G359S, K366R, A371V, A376V, K390R, K395R, A400T, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2214 2214 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178IM, T200I, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390KR, K395R, A400T, T403M, E432D, R461K, D471E, Q480H, H483Q, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
2216 2216 None None   E6D, K11T, V35T, T39E, I50IT, T69N, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, T200TA, Q207S, R211S, V245E, A272AS, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, I375V, A400T, T403M, E432D, N447S, D460N, D471E, Q480H, H483Y, L491S, S515L, L517V, S519N, Q524E, A534S, A554S  
2221 2221 None None   E6D, K11T, V35T, D121H, K122E, D123N, S162C, K173I, Q174K, D177E, Q207S, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
2224 2224 None None   E6D, K11KT, V35T, T39S, W88C, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, K275R, K281R, T286A, E291D, V292I, I293V, E297EK, A304E, E312T, I329V, G335D, M357K, G359S, K366R, A371V, A376V, K390R, K395R, A400T, T403M, E432D, N447S, V467I, D471E, H483Q, L491S, K512R, L517V, S519N, Q524E, E529D, K530R, A534S, A554S  
2225 2225 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178V, T200I, Q207A, R211S, V245E, E291D, V292I, I293V, E297AT, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, I375V, K395R, A400T, T403M, E432D, N447S, S468P, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, E529D, A534S, A554S  
2227 2227 None None K219KR  E6D, K11T, V35T, T39K, K43E, D123N, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, K277R, T286A, E291D, V292I, I293V, E297T, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376T, V381I, K390R, K395R, A400T, T403M, E432D, N447S, L452V, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2228 2228 None None   E6D, K11T, V35T, K122E, D123S, I142V, S162C, K173I, Q174K, D177E, V189I, Q207S, R211S, K238R, V245A, T286A, E291D, V292I, E312T, I326V, I329V, G335D, A355G, M357K, G359S, K366R, A371V, K388R, K390R, A400T, T403M, E432D, N447S, D471E, Q480Y, I482V, H483Y, L491S, A502V, I505V, K512R, L517V, S519N, Q524E, A534S, A554S  
2230 2230 None None V75VL  E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, T200I, Q207D, R211S, K238R, V245E, V276I, T286A, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2232 2232 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, K311R, E312T, V317G, I326V, I329V, G335D, M357K, G359S, K366R, T369TA, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, E529D, A534S, A554S  
2235 2235 None None   K20R, V35T, E36A, T39E, S48T, I50V, E53D, V60I, T69S, T107S, S162C, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, V317VA, D324E, G335D, E344EV, R356K, G359T, A376S, T377M, T386I, K390R, A400T, E404D, E432D, V435A, A437V, L452I, Q464K, V466VI, H483Y, L484I, L491S, S519N, K530R, V531I, A534S, A554S  
2237 2237 None None   E6D, V8I, K11T, V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, I178M, T200IR, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395KR, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2239 2239 None None   V35T, T39N, S48T, V60I, V111I, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, V317A, G335D, R356K, G359T, T377M, K390R, A400T, E404D, E432D, V435A, A437V, L452M, Q464K, D471E, H483C, L484I, L491S, S519N, I526V, K530R, A534S, A554S  
2243 2243 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, E291D, V292I, I293V, K311A, E312N, I326V, I329V, G335D, M357K, G359S, K366R, T369A, E370D, A371V, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
2244 2244 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, E291D, V292I, I293V, K311A, E312N, I326V, I329V, G335D, M357K, G359S, K366R, T369A, E370D, A371V, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
2250 2250 None None   E6D, K11T, V35T, D123S, S162C, K173T, Q174K, D177E, Q207S, R211S, K238R, V245E, T286A, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
2251 2251 None None   E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, V179VI, T200I, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2253 2253 None None   E6D, K11T, V21I, V35T, T39K, V60VI, K122E, D123S, I135IATV, S162C, K173R, Q174K, D177E, I178M, G196E, Q207S, R211S, K238R, V245E, T286A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, K350R, M357K, G359S, K366R, A371V, V372VI, A400T, T403M, E432D, N447S, R463K, D471E, Q480H, H483Y, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
2254 2254 None None   E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E, A272AG, E291D, V292I, I293V, E312T, I326V, I329V, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, V435VI, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2255 2255 None None   E6D, K11T, V35T, K122E, D123S, I135T, S162C, K173M, Q174K, D177E, I178M, T200A, Q207S, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, V381I, K390R, K395R, A400T, E432D, N447S, D471E, Q480H, H483HY, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
2261 2261 None None   E6D, K11T, V35T, T39R, K43E, K122E, D123S, S162C, Q207E, R211K, K238R, V245E, T286A, E291D, V292I, I293V, K311R, E312K, I326V, I329V, G335D, M357K, G359S, K366R, A400T, T403M, E432D, N447S, D471E, Q480H, L491T, K512R, L517V, S519N, Q524E, K530R, A534S, A554S  
2264 2264 None None   E6D, T7V, K11T, V35T, T39K, K43E, K122E, D123S, I135T, K173I, Q174K, D177E, I178V, T200I, Q207A, R211S, F214L, K238R, V245K, T286A, E291D, V292I, I293V, E312N, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K395R, A400T, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2267 2267 None None V75VL  E6D, K11T, V35T, T39K, K43E, V106I, K122E, D123S, T139A, S162C, K173I, Q174K, D177E, I178M, Q207A, R211S, K238KR, V245E, I274IV, T286A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, E399ED, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2270 2270 None None   E6D, K11T, V35T, T39K, K122E, D123N, S162C, K173I, Q174K, D177E, Q207S, R211S, V245E, K281R, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, A371V, K390R, A400T, T403M, E432D, N447S, L452I, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
2272 2272 None None   E6D, K11T, V35T, T39E, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, I178M, Q207N, R211S, K238R, V245E, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, V435I, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2274 2274 None None   E6D, K11T, V35T, T39E, K122E, D123S, K173I, Q174K, D177E, I178M, T200L, Q207A, R211S, K238R, V245E, K281R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376V, K390R, K395R, A400T, T403M, E432D, N447S, V467I, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2275 2275 None None   V35T, T39K, K43E, K122E, D123S, K166KR, K173R, Q174R, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376S, T386I, K390R, K395R, A400T, T403M, E432D, V467I, D471E, Q480H, H483Q, L491S, K512R, E516ED, L517V, Q524E, A534S, A554S S519A 
2276 2276 None None   E6D, K11T, V35T, T39K, D123ST, S162C, K173I, Q174K, D177E, Q207N, R211S, K238R, V245E, V276I, T286A, E291D, V292I, I293V, K311R, E312T, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, N447S, D471E, Q480H, H483Y, L491S, A502V, K512R, L517V, S519N, Q524E, A534S, A554S I482M 
2278 2278 None None   V35T, T39N, S48T, V60I, V245K, A272P, K277R, E291D, V292I, I293V, V317A, G335D, R356K, G359T, T377M, K390KR, A400T, E404D, E432D, V435A, A437V, L452M, Q464K, D471E, H483C, L484I, L491S, S519N, K530R, A534S, A554S  
2279 2279 None None   V35T, E36EA, T39D, S48T, V60I, V245H, A272P, K277R, E291D, V292I, I293V, V317A, G335D, R356K, G359T, A376AT, T377M, A400T, E404D, E432D, V435A, L452M, Q464K, D471E, H483C, L484I, L491S, S519N, K530R, A534S, A554S  
2280 2280 None None   E6D, V35T, T39E, T107S, K122E, D123N, K173T, Q174K, D177E, G196E, Q207S, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326IV, I329V, M357K, G359S, K366R, A371V, S379G, V381I, K390R, A400T, T403M, E432D, V435A, N447S, D471E, Q480H, H483Y, L491S, A508S, K512R, L517V, S519N, Q524E, A534S, Q547K, A554K  
2281 2281 None None   V35T, T39N, S48T, V60I, V245Q, A272P, V276A, K277R, E291D, V292I, I293V, V317A, G335D, R356K, G359T, T377M, K390R, A400T, E404D, E432D, V435A, A437V, L452M, Q464K, D471E, H483C, L484I, L491S, S519N, K530R, A534S, A554S  
2283 2283 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, K281KR, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, F346Y, M357K, G359S, K366R, A371V, A400T, E432D, V435I, G436E, N447S, D460N, D471E, T477S, Q480H, L491S, E492K, K512R, L517I, S519N, Q524E, I526V, A534S, A554S  
2287 2287 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, T200I, Q207A, R211S, K238R, V245E, T286A, E291D, E300Q, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, S379G, V381VI, K390R, A400T, E432D, N447S, D471E, Q480H, H483Q, L491S, I505IV, K512R, L517V, S519N, Q524E, K530R, A534S, A554S  
2290 2290 None None   K11T, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, Q207S, R211S, K238R, V245E, K281R, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, A371V, K390R, A400T, T403M, E432D, N447S, V466I, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
2291 2291 None None   E6D, V35T, T39K, K43R, V60I, K101R, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, T200S, R211T, K238R, V245E, K281R, T286A, E291D, V292I, I293V, K311Q, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554L  
2303 2303 None None   E6D, K11T, K20R, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, T200I, Q207N, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390KR, A400T, T403M, E432D, N447S, D471E, Q480QH, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2306 2306 None None   E6D, K11T, K20R, V35I, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, T200I, Q207A, R211S, K238R, V245AE, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
2308 2308 None None   E6D, K11T, V35T, T39K, K122E, D123N, S162C, K173I, Q174K, D177E, I178M, T200A, Q207S, R211S, K238R, V245E, E291D, I293V, E312NT, I326V, I329V, G335D, Y342F, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403MR, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, Q524E, A534S, A554S  
2309 2309 None None   E6D, K11T, K20R, V35T, T39K, K43E, V118I, K122E, D123N, I135T, T165I, K173I, Q174K, D177E, I178V, T200I, Q207A, R211S, F214L, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, M357K, G359S, K366R, A371V, I382T, K390R, A400T, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, E529D, A534S, A554T