<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Porter (2014)
Title Characterization of HIV-1 drug resistance development through week 48 in antiretroviral naive subjects on rilpivirine/emtricitabine/tenofovir DF or efavirenz/emtricitabine/tenofovir DF in the STaR study (GS-US-264-0110)
Citation JAIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 35
NumPts 17
Subtype B

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
STaR1 STaR1_B None None   V35I, K122E, D123N, I135L, S162C, K173N, Q174K, V179I, G196E, A272P, A288T  
  STaR1_WK12 TDF, FTC RPV M184V Y181I V35I, V90I, K122E, D123N, I135L, S162C, Q174K, V179I, G196E, A272P, A288T  
  STaR1_WK24 TDF, FTC RPV M184V K101KE, Y181I V35IM, V90I, K122E, D123N, I135L, S162C, Q174K, V179I, G196E, A272P, A288T G45GEKR 
STaR10 STaR10_B None None   K11KR, V35I, R83K, T200TA, Q207A, R211K, I293V  
  STaR10_WK24 TDF, FTC RPV L74V, M184V L100I, K103N, P225H V35I, Q207A, R211K, I293V  
STaR11 STaR11_B None None   V35E, T39A, D177E, G196E, Q207E, R211K, V245K, I257L, K277R, T286A, I293V  
  STaR11_WK12 TDF, FTC RPV M184V E138K, Y181I V35E, T39A, D177E, V179VI, E194EK, G196EK, Q207E, R211K, V245K, I257L, K277R, T286A, I293V  
STaR12 STaR12_B None None   V35I, R83K, D177E, G196E, H208HY, L210LF, R211K, E291D, E297K  
  STaR12_WK40 TDF, FTC RPV K65R, T69T_X, K219KE Y181C, Y188H K11T, V35I, E40K, I135L, D177E, I178M, V179VI, V189VI, G196E, E291D, E297K  
STaR13 STaR13_B None None   V8I, K20R, T69TA, K122KE, D123X, I178IM, R211K, V245VI, E248ED, A272P, K277R, I293V, P294S, E297R  
  STar13_WK8 TDF, FTC RPV M184I A98AG, K101KE, E138EK, Y181YC V8I, K20R, K122KE, D123DGNS, I178IM, R211K, H221HY, V245I, E248ED, A272P, K277KR, I293V, P294S, E297R  
STaR14 STaR14_B None None   S48T, R211N, V245N, L283I, V292I, I293V  
  STaR14_WK21 TDF, FTC RPV Y115YF, M184I, K219KE K101E, Y181YC S48T, V90VI, R211N, V245N, L283I, V292I, I293V  
STaR15 STaR15_B None None   F171Y, D177E, I178IMV, T200A, Q207T, R211K, V245E, A272P, K277KR  
  STaR15_WK48 TDF, FTC RPV A62AV, K65KN, M184MIV V108VI, F227FC, L234LI K20KR, F171Y, D177E, I178IMV, T200A, Q207T, R211K, L228LR, M230MI, V245E, A272P  
STaR16 STaR16_B None None  V179DE T39S, S48T, V60I, S68G, K102Q, K122KE, D123X, A158S, I178L, I195IL, T200TA, R211K, I244V, V245E, A272P, K277KR, R284K, A288S, V292I, I293V, E297A  
  STaR16_WK48 TDF, FTC RPV  V179E T39S, S48T, V60VI, S68G, V90VI, K102Q, K122E, D123S, A158S, I178L, V189VI, E203ED, R211K, I244V, V245E, A272P, R284K, A288S, V292I, I293V, E297A K66N 
STaR17 STaR17_B None None   A98S, K122E, A158AS, I159IV, S162SA, D177E, G196E, R211S, A272S, T286A, P294T  
  STaR17_WK48 TDF, FTC RPV K70KE, M184I E138K V90I, A98S, K122E, A158S, S162A, D177E, G196E, R211S, A272S, T286A, P294T  
STaR2 STaR2_B None None  V179VD V8VI, K20KR, V35I, D123E, I135T, K173T, Q174K, D177E, G196E, T200K, Q207A, P243T, V245K, D256E, A272AP, T286TA, E291D, V292I, I293V, E297A  
  STaR2_WK8 TDF, FTC RPV M184V K101KE, Y181I K20R, V35I, V106VI, D123E, I135T, K173T, Q174K, D177E, G196E, T200K, Q207A, P243T, V245K, D256E, A272P, E291D, V292I, I293V, E297A  
STaR3 STaR3_B None None   E6ED, V8VI, V35I, D86DE, K122P, D123E, I135L, T139I, D177E, Q207QK, R211RK, A272P, T286A, A288AG, I293IV  
  STaR3_WK24 TDF, FTC RPV M184I K238N V35I, G45GE, V90VI, K122P, D123EK, I135L, T139I, D177AE, I195IK, A272P, A288G, I293V, P294T  
STaR4 STaR4_B None None   V35M, K49KR, V60I, R83K, K122E, I135T, S162H, E248D, A272P, E297K  
  STaR4_WK16 TDF, FTC RPV M184I E138K V35M, V60I, R83K, K122E, I135T, S162H, V189VI, H221HY, E248D, A272P, E297K  
STaR5 STaR5_B None None   K20R, V35L, T39A, R83RK, K122E, I135R, K173E, D177E, V179I, G196E, T200I, I202V, R211K, V245VE, A288S, I293V  
  STaR5_WK16 TDF, FTC RPV M184V Y181C K20R, V35L, T39A, K122E, D123DN, I135R, K173E, Q174QR, D177E, V179I, G196E, T200I, I202IV, R211K, K249KR, A288S, I293V  
STaR6 STaR6_B None None   V35I, A98S, K122E, K166KR, I178IL, R211K, V245E, K277R, I293V, P294A, E297K L80LF, T128TA 
  STaR6_WK40 TDF, FTC RPV D67G, M184I, K219E K101E, Y181C, M230L V35I, A98S, K122E, D123G, T200A, V245E, K277R, I293V, P294A, E297K  
STaR7 STaR7_B None None   T39TA, T69TA, K82KR, R83RK, S162SN, P170PL, K173Q, I178M, T200A, Q207E, R211K, P225PL, L228LF, A272P, K277KR, I293V, T296S, E297A L282LF 
  STaR7_WK16 TDF, FTC RPV M184I E138KQ K82R, R83K, K173Q, I178M, T200A, Q207E, R211K, L228I, A272P, K277R, I293V, T296S, E297A  
STaR8 STaR8_B None None   V35T, E40ED, V60I, K122KE, I135V, S162A, K173T, Q174EK, P176PS, D177E, I178M, T200A, E204EK, Q207E, R211K, V245Q, A272P, K277R, K281R, T286A, I293V, P294T  
  STaR8_WK12 TDF, FTC RPV M184I E138K V35T, T39TS, E40ED, V60I, V90VI, I135V, S162A, K173T, Q174E, D177E, I178M, T200A, E204EK, Q207E, R211K, H221HY, V245Q, A272P, K277R, K281R, T286A, I293V, P294T  
STaR9 STaR9_B None None   K20KR, V60I, S68G, I178ILM, G196E, T200TA, E248D, A272P, K275R, K281KR, V292I, I293V G273R 
  STaR9_WK37 TDF, FTC RPV K65KR, M184MIV  V35VL, V60I, S68SG, I178L, G196E, E204EG, E248D, A272P, K275R, V292I, I293V G273R