<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Zeng (2012)
Title Emergence of a new HIV type 1 CRF01_AE variant in Guangxi, southern China.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 222
NumPts 222
Subtype CRF01_AE, C, B


  Page 1 of 3    Next >   Last Page Jump to Page   
Back To Query
Page 1   from Isolate 1 to Isolate 100 from Total 222 Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
CN0031 CN0031 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, V317T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN0037 CN0037 None None   V35T, T39N, S48T, E53D, V60I, T69S, I135V, S162C, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, V317A, D324E, G335D, R356K, G359T, T377M, K390R, A400T, E404D, E432D, V435A, L452I, R461K, Q464K, H483Y, L484I, L491S, S519N, Q524E, K530R, A534S, A554N  
CN0040 CN0040 None None   E6D, K11A, V21I, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, T200A, Q207K, R211S, K238R, V245E, K281R, L283I, T286A, E291D, V292I, I293V, E312N, S322T, I326V, I329V, G335D, R356K, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, D460S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN0050 CN0050 None None   E6D, V35T, T39K, K43E, V60I, K122E, D123S, S162C, K173I, Q174K, D177E, T200A, Q207S, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, K530R, A534S, A554S  
CN0059 CN0059 None None   E6D, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, K238R, I244V, V245E, E248T, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, Q334E, M357K, R358S, G359S, K366R, A371V, I375V, K390R, K395R, A400T, V435E, D460N, V466A, D471E, Q480H, L491S, K512S, L517I, S519N, Q524E, A534S, A554S  
CN0269 CN0269 None None   E6D, K11T, V35T, T39K, K122E, D123S, K173M, Q174K, D177E, I178M, V179I, T200I, Q207A, R211S, K238R, I244V, V245E, E248D, T286A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A400T, T403M, E432D, N447S, D471E, K476R, H483Q, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
CN0274 CN0274 None None   E6D, K11T, V35T, T39K, K43E, V60I, K122E, D123S, I142V, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E, K249R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN0290 CN0290 None None   E28K, A33T, V35T, E36A, T39A, S48T, V60I, D121Y, K122E, V245Q, E248V, K249Q, A272P, K277R, L282P, E291D, V292I, I293V, I309L, G335D, T338S, R356K, G359T, K366R, T377M, K390R, A400T, E404D, E432D, V435A, A437V, L452I, Q464K, D471E, Q480H, H483C, L491S, S519N, K530R, A534S, A554N D76N, S191F 
CN0291 CN0291 None None   E6N, V8I, K11S, V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357R, R358G, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, V467I, D471E, Q480H, L491S, L517V, S519N, Q524E, A534S, A554S  
CN0339 CN0339 None None   E6D, K11T, E28K, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207K, R211S, K238R, V245E, K277R, T286A, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, Q464K, V467I, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN0340 CN0340 None None   V35T, T39N, S48T, E53D, V60I, T69S, K122E, I135V, S162C, Q207E, R211K, V245E, A272P, K275R, K277R, E291D, V292I, I293V, V317A, D324E, G335D, R356K, G359A, T377M, T386V, A400T, E404D, E432D, V435A, Q464K, H483Y, L484I, L491S, S519N, A534S, A554N  
CN0665 CN0665 None None   E6D, K11T, V35T, T39N, K122E, D123N, S162C, K173I, Q174K, D177E, I178M, T200E, Q207S, R211S, K238R, V245E, E291D, I293V, E312T, I326V, I329V, G335D, Y342F, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, Q524E, A534S, A554S  
CN0666 CN0666 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123N, S162C, F171Y, K173R, Q174K, D177E, I178M, V179I, Q207A, R211S, K238R, V245E, K275R, T286A, E291D, V292I, I293V, E312T, V317T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T377M, K390R, A400T, T403M, N447S, T470S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN0668 CN0668 None None   E6D, K11T, V35T, D123N, S162C, K173I, Q174K, D177E, Q207S, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312N, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, E432D, D460N, D471E, Q480H, H483L, L484I, S489A, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN0673 CN0673 None None   V35T, T39N, S48T, V60I, V90I, K102R, D121H, K122E, I135K, T139I, Q197E, R211G, V245K, A272P, K277R, T286V, E291D, V292I, I293V, V317A, G335D, R356K, G359T, T377M, K390R, A400T, E404D, E432D, V435A, L452I, Q464K, D471E, H483Y, L484I, L491S, S519N, Q520L, K527N, K530R, A534S, A554S  
CN0691 CN0691 None None   E6D, K11T, V35T, T39K, K43E, E44G, K122E, D123S, I135T, K173I, Q174K, D177E, Q197H, T200R, Q207A, R211S, K238R, I244V, V245E, E291D, V292I, I293V, E312T, S322T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T386I, K390R, K395R, A400I, T403M, V435I, N447S, L452V, V467A, D471E, K476Q, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN0692 CN0692 None None   E6D, K11T, V35T, T39K, K43E, D123N, I135T, K173I, Q174K, D177E, Q197H, T200R, Q207A, R211S, K238R, I244V, V245E, W252R, E291D, V292I, I293V, E312T, S322T, I326V, I329V, G335D, G352R, M357K, G359S, K366R, A371V, T386I, K390R, K395R, A400I, T403M, Q428H, E432D, V435I, N447S, D471E, Q480H, H483Q, L491S, L517V, S519N, Q524E, A534S, H539R, A554S N137S 
CN0694 CN0694 None None   V35T, E36A, T39D, S48T, E53D, V60I, I135V, S162C, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, K311T, G335D, R356K, M357L, G359T, T386V, K390R, A400T, E404D, E432D, V435A, A437V, L452I, R463G, Q464K, V466I, D471E, H483Y, L484I, L491S, S519N, K530R, A534S, A554S P55L, K126N, D185G, L391S 
CN0696 CN0696 None None   E6N, K11T, T27A, V35T, K122E, D123K, I135T, S162C, K173I, Q174K, D177E, I178M, T200A, Q207S, R211S, K238R, V245E, E291D, V292I, I293V, E312T, I329V, G335D, M357K, G359S, K366R, A371V, K395R, A400T, E432D, N447S, V467A, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S R172G 
CN0699 CN0699 None None K70R  E6D, K11T, V35T, T39K, V106I, K122E, D123N, K154E, S162C, K173T, Q174K, D177E, I178M, T200A, Q207N, R211S, V245E, I293V, E312T, I326V, I329V, G335D, Y342F, M357K, G359S, K366R, T369A, A371V, K390R, A400T, T403M, E432D, V435I, N447S, D460G, D471E, Q480H, L486S, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN0700 CN0700 None None   V35T, E36A, T39D, S48T, E53D, V60I, T69S, I135V, S162C, Q207E, R211K, V245Q, A272S, K275R, K277R, T286A, E291D, V292I, I293V, V317A, D324E, G335D, R356K, G359A, T377M, T386I, K390R, A400T, E404D, K431Q, E432D, V435A, A437V, L452I, R461K, Q464K, H483Y, L484I, L491S, S519N, K530R, A534S, P537S, A554N E89G 
CN0891 CN0891 None None   V35T, E36A, T39D, S48T, E53D, V60I, T69S, I135V, S162C, Q207E, R211K, V245E, A272P, K277R, T286A, E291D, V292I, I293V, V317A, D324E, G335D, E344V, R356K, G359T, I375M, T377M, K390R, A400T, E404D, E432D, V435A, A437V, L452I, Q464K, V466I, T477S, H483Y, L484I, L491S, Q509K, S519N, A534S, A554N L80P, Q340R 
CN0892 CN0892 None None   E6D, V10I, V35T, T39K, K43E, S48P, K122E, D123N, K173M, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E, K259E, K281R, T286A, E291D, V292I, I293V, E297K, L301I, R307K, E308R, I309V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369V, A371V, I375V, A376T, K390R, A400T, E432D, V435E, N447S, S468H, D471E, Q480H, H483Q, L491S, I505V, K512R, L517V, S519N, E523G, Q524E, A534S, A554S G273R, G316R, Y342H 
CN0896 CN0896 None None   V35I, T39N, S48T, E53D, V60I, T69S, I135V, T200I, Q207E, P243L, V245K, S251V, A272P, K277R, T286A, I293V, D324E, Q334H, G335D, R356K, G359T, T377Q, T386I, A400T, E404D, E432D, V435A, A437V, L452I, Q464K, T473A, H483Y, L484I, L491S, S519N, K527S, K530R, A534S, A554N  
CN0897 CN0897 None None   V35T, E36A, T39D, S48T, E53D, V60I, K64R, T69S, I135R, Q207E, R211K, V245Q, A272P, K277R, T286V, E291D, I293V, H315Q, V317A, D324E, G335D, R356K, G359T, T377M, T386I, K390R, A400T, E404D, E432D, V435A, A437V, L452I, Q464K, H483Y, L484T, L491S, S519N, K530R, A534S, A554N  
CN0899 CN0899 None None   V35T, T39N, S48T, E53D, V60I, T69S, I135V, S162C, Q207E, R211K, V245E, A272P, K277R, T286A, V292I, I293V, K311R, V317A, D324E, G335D, R356K, G359A, T377M, T386I, A400T, E404D, E432D, V435A, A437V, L452I, Q464K, H483Y, L484I, L491S, S519N, K530R, A534S, A554N  
CN0900 CN0900 None None  V179D E6D, V35T, T39K, K43E, V111I, K122E, D123S, K173I, Q174K, T200A, Q207A, R211S, K238R, I244V, V245E, A272P, V276I, T286A, I293V, E312T, I326V, I329V, Q334E, G335D, P345Q, R356K, M357R, R358G, G359S, A371V, K390R, K395R, A400T, T403M, V435G, V466A, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
CN0901 CN0901 None None   E6D, V35T, T39K, K43E, K122E, D123S, K166R, K173I, Q174K, D177E, Q207A, R211S, K238R, I244V, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, Q334E, M357K, R358S, G359S, K366R, A371V, K390R, K395R, A400T, T403M, V435G, V466A, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
CN0918 CN0918 None None   E6D, K11T, V35T, T39R, K122E, D123N, I135L, S162C, K173I, Q174K, D177E, T200I, Q207N, R211S, K238R, V245A, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, A355G, M357K, G359S, K366R, A371V, T386I, K390R, K395R, A400T, E432D, Q464K, D471E, Q480Y, I482V, H483Y, L491S, A502V, K512R, L517V, S519N, Q524E, V531I, A534S, A554S  
CN0922 CN0922 None None   V35T, E36A, T39D, S48T, E53D, V60I, T69S, G112A, K166R, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, A304E, D324E, G335D, R356K, G359T, A376S, T377M, T386I, K390R, A400T, E404D, E432D, V435A, L452I, Q464K, H483Y, L484I, Q487K, L491S, S519N, K530R, A534S, A554N  
CN0944 CN0944 None None   V35T, E36A, T39D, S48T, V60I, D121Y, K122E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, P294S, H315Q, V317A, G335D, P345Q, R356K, G359T, T377M, K390R, A400T, E404D, E432D, V435I, L452I, Q464K, D471E, H483F, L484I, L491S, S519N, K530R, A534S, V548I, A554S  
CN0951 CN0951 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, F214L, K238R, V245E, E291D, V292I, I293V, L301F, E312T, V317A, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, L452Q, V467I, S468T, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN0955 CN0955 None None   V35T, E36A, T39D, K43R, S48T, V60I, D121Y, K122E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, G335D, R356K, G359T, E370K, T377M, K390R, A400T, E404D, E432D, L452Q, Q464K, D471E, H483C, L484I, L491S, S519N, K530R, A534S, A554S P55L, L149P 
CN0973 CN0973 None None   E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, K173T, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, T286A, A288T, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, V467I, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN0981 CN0981 None None   E6D, V35T, T39K, K43E, V60I, K102R, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, T200I, Q207A, R211S, V245E, K281R, T286A, E291D, V292I, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN0982 CN0982 None None   E6D, V8I, K11S, V35T, T39K, K43E, S68G, E79D, V118I, K122E, D123N, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E, A272P, I274V, T290A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, Y342F, M357K, G359S, V365A, K366R, A371V, K390R, A400T, T403M, E404D, T419I, E432D, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN0984 CN0984 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123N, K173I, Q174K, D177E, I178M, V179I, T200I, Q207A, R211S, K238R, V245E, K281R, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, A376T, K390R, K395R, A400T, E432D, T439A, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, E529D, A534S, A554T, V559A R78G 
CN0985 CN0985 None None   K32R, V35T, T39N, S48T, E53D, V60I, T69S, I135V, S162C, Q197R, Q207E, V245E, S251G, A272P, K277R, T286A, E291D, I293V, D324E, G335D, R356K, G359T, T377M, T386I, E396D, A400T, E404D, E432D, L452I, D460N, Q464K, L469I, H483Y, L484I, Q487K, L491S, S519N, K527R, K530R, A534S, A554S S191P 
CN0986 CN0986 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, E514D, Q524E, A534S, A554S, V559I G504R, A508P, S519K, Q520d, I521d, E523R, W535C, V536Q, A538d, H539d, K540d, G543E, G544d, N545H, R557N, K558G 
CN0988 CN0988 None None   V35T, E36A, T39D, S48T, E53D, V60I, T69S, I135V, S162C, Q207E, R211K, V245Q, A272P, K277R, T286A, V292I, I293V, D324E, G335D, R356K, G359T, T377I, K390R, A400T, E404D, E432D, V435A, A437V, L452V, Q464K, V466I, H483Y, L484I, L491S, S519N, K527R, K530R, A534S, A554T V317R 
CN0993 CN0993 None None   V35T, T39N, S48T, E53D, V60I, T69S, I135V, S162C, Q207E, R211K, V245Q, E248T, A272P, V292I, I293V, A304E, V317A, D324E, G335D, R356K, G359T, T377M, T386I, A400T, E404D, E432D, V435A, A437V, L452I, Q464K, H483Y, L484I, L491S, L517I, S519N, K530R, A534S, A554N  
CN0999 CN0999 None None   V21I, V35T, E36A, T39E, S48T, V60I, D121Y, K122E, D177G, V245H, A272P, K277R, T286A, V292I, I293V, G335D, R356K, G359T, T377M, K390R, A400T, E404D, E432D, L452M, Q464K, V466I, D471E, H483C, L484I, L491S, S519N, K530R, A534S, A554S  
CN1001 CN1001 None None   E6D, K11A, V35T, T39K, K43E, S48P, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, K277R, T286A, E291D, V292I, I293V, E297A, A304E, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403V, E432D, N447S, R461K, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S M164V, D186G 
CN1002 CN1002 None None   E6D, K11T, V35T, T39K, K43E, D123N, K173I, Q174K, D177E, G196E, T200I, Q207A, R211S, F214L, K238R, V245E, K277R, T286A, E291D, V292I, I293V, E297T, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376S, K390R, K395R, A400T, T403M, E432D, N447S, S468P, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1003 CN1003 None None   E6D, K11T, V35T, T39K, K43E, V118I, D123N, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, V276I, T286A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376S, K390R, K395R, A400T, T403M, E432D, N447S, S468P, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S K220M 
CN1207 CN1207 None None   E6D, V21I, V35T, T39K, K43E, V60I, K104R, K122E, D123S, I135V, S162C, T165I, K173R, D177E, Q207A, R211S, K238R, I244V, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, Q334E, M357K, R358S, G359S, K366R, A371V, I375V, A400T, T403M, Q428R, V435G, V466A, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
CN1211 CN1211 None None   E6D, K11T, V35T, T39N, V60I, V106I, T107S, K122E, D123S, S162C, K173A, Q174K, D177E, Q207S, R211S, K238R, V245E, E291D, V292I, I293V, E312S, V317A, I329V, G335D, M357K, G359S, K366R, A371V, S379G, T386I, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1212 CN1212 None None   E6D, K11T, V21I, V35T, K122E, D123N, S162C, K173I, Q174K, D177E, Q207S, R211S, K238R, V245E, K277R, K281R, L283I, E291D, I293V, K311R, E312T, I329V, G335D, M357K, G359S, K366R, A371V, A400T, T403M, N447S, S468H, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
CN1213 CN1213 None None   E6D, K11T, V35T, T39K, K43E, K103E, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, I270V, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357R, G359S, K366R, T369A, A371V, T377I, I382T, A400T, T403M, K424R, W426R, E432D, D471E, T473A, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S N136H 
CN1214 CN1214 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, T200I, Q207A, R211S, K238R, V245E, K281R, T286A, E291D, V292I, I293V, E312T, I326V, E328D, I329V, G335D, Y342F, M357K, G359S, K366R, A371V, K385R, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1217 CN1217 None None   E6D, V8I, V35T, T39K, K43E, V118I, K122E, D123S, I135T, S162C, K173I, Q174K, I178M, T200A, I202V, Q207N, R211S, K238R, V245E, T286A, V292I, I293V, P294Q, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A400T, T403M, E432D, N447S, D471E, Q480H, H483Y, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S, K558R  
CN1218 CN1218 None None   E6D, V35T, T39K, K43E, K122E, D123N, S162C, K173R, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, E344D, M357K, G359S, K366R, T369A, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1220 CN1220 None None   E6N, K11S, V35T, T39K, K43E, K122E, D123N, I135T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, I244V, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T386I, K390R, A400T, T403M, E404D, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S S117L 
CN1221 CN1221 None None   E6D, K11S, V35T, T39K, K43E, K122E, D123N, I135T, K173I, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T386I, K390R, A400T, T403M, E404D, E432D, N447S, V458I, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, H539R, A554S N147S, I293A 
CN1222 CN1222 None None   E6D, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, Q207A, R211S, K238R, V245E, T286A, A288S, I293V, E297A, E312T, I329V, G335D, M357K, G359S, K366R, A371V, V381I, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, Q524E, A534S, A554H, K558R  
CN1223 CN1223 None None   E6N, K11T, V35T, T39K, K43E, K122E, D123S, I135V, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357R, G359S, K366R, T369A, A371V, T377M, I382T, K390R, K395R, A400T, T403M, E404D, E432D, N447S, D471E, H483Q, L491S, K512R, S515A, L517V, S519N, Q524E, A534S, A554S  
CN1224 CN1224 None None   E6D, K11T, V35T, T39K, K43Q, K122E, D123S, S162C, K173I, Q174K, D177E, Q207S, R211S, V245E, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, I375V, K395R, A400T, T403M, E432D, N447S, D460N, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1225 CN1225 None None   E6D, K11T, V35T, T39N, V60I, K122E, D123S, K173I, Q174K, D177G, T200A, I202V, Q207S, R211S, K238R, V245E, K281R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, V435E, N447S, D460N, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1226 CN1226 None None   V35T, T39N, S48T, V60I, R211K, V245H, A272P, V276I, K277R, E291D, V292I, I293V, V317A, I326V, G335D, R356K, G359T, T377M, A400T, E404D, E432D, V435A, L452M, Q464K, D471E, H483C, L484I, L491S, S519N, K530R, A534S, A554S  
CN1236 CN1236 None None   E6D, K11T, V35T, T39K, E40G, K43E, K122E, D123N, I135T, S162C, F171Y, K173R, Q174K, D177E, I178M, V179I, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, V317T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T377M, T386I, K390R, A400T, T403M, N447S, T470S, D471E, Q480H, L491S, I495M, K512R, L517V, S519N, Q524E, A534S, A554S V60T, D256G, N348G 
CN1239 CN1239 None None V75M  E6D, K11T, V35T, T39E, K43R, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, V179I, Q207K, R211S, L228R, K238R, V245E, K275R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, E432D, N447S, D460N, D471E, Q480H, H483Y, G490E, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1242 CN1242 None None   E6D, K11T, V35T, T39E, K122E, D123K, S162C, K173I, Q174K, D177E, T200E, Q207S, R211S, K238R, V245E, T286A, I293V, K311R, E312T, G335D, M357K, G359S, K366R, A371V, I375V, A400T, T403M, E432D, N447S, D460N, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1256 CN1256 None None   E6N, K11T, V35T, T39K, K43E, K122E, D123S, S162C, K173R, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E297V, E312T, V317T, I326V, I329V, G335D, T338A, M357K, G359S, K366R, A371V, T377M, K390R, A400T, T403M, N447S, D471E, Q480H, L491S, L517V, S519N, Q524E, A534S, A554S  
CN1257 CN1257 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, I274V, T286A, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, I375V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1265 CN1265 None None   E6D, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, T200I, Q207A, R211S, K238R, I244V, V245E, E248Q, A272P, V276I, T286A, V292I, I293V, E297K, K311N, E312T, I326V, I329V, Q334E, G335D, M357K, R358S, G359S, K366R, A371V, K390R, K395R, A400T, T403M, V435G, V466A, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, E529D, A534S, A554S  
CN1268 CN1268 None None   E6D, K11T, V35T, T39E, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, I202V, Q207S, R211S, V245E, V276I, L283I, E291D, V292I, I293V, E312T, I326V, G335D, M357K, G359S, K366R, A371V, A376V, T386A, K390R, A400T, T403M, E432D, D471E, Q480H, H483Y, L491S, K512R, E514D, L517I, S519N, Q524E, K527R, A534S, A554S  
CN1270 CN1270 None None   E6D, K11T, V35T, T39E, K122E, D123S, K173I, Q174K, D177E, I178M, T200L, Q207A, R211S, K238R, V245E, K281R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, V467I, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S L100S 
CN1272 CN1272 None None   E6D, V35T, T39E, D121H, K122E, I135R, S162C, K173T, Q174E, D177E, I178M, Q207R, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, E529D, A534S, Q547K, K558R  
CN1273 CN1273 None None   E6D, K11T, V35T, K122E, D123S, S162C, K173I, Q174K, D177E, T200A, Q207K, R211S, K238R, V245E, V276I, K281R, L283I, T286A, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, K530R, A534S, A554S  
CN1287 CN1287 None None   E6D, V8I, K11T, V35T, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376S, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491T, K512R, E514D, L517V, S519N, Q524E, K530R, A534S, A554S  
CN1288 CN1288 None None   P4H, E6D, K11T, V35T, K122E, D123S, S162C, K173L, Q174K, D177E, I178M, T200A, E203D, Q207S, R211S, V245E, K281R, E291D, I293V, E312T, I326V, I329V, Q334L, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, T450N, V458I, D471E, Q480H, H483Y, L491S, K512R, E514D, L517V, S519N, Q524E, K530R, A534S, A554S  
CN1289 CN1289 None None  V179D E6D, K11T, V35T, T39K, K43E, V111I, K122E, D123S, I135V, K173I, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, A272P, T286A, E291D, V292I, I293V, K311Q, E312T, D324E, I329V, G335D, M357K, G359S, K366R, A371V, I382L, K390R, E399D, A400T, T403M, E432D, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1291 CN1291 None None   E6D, K11T, V35T, T39E, V118I, K122E, D123S, S162C, K173I, Q174K, D177E, I202V, Q207G, R211S, K238R, V245E, A272P, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
CN1293 CN1293 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, P294S, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371AV, I375V, A376S, T377I, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1295 CN1295 None None   E6D, K11T, V35T, T39N, K122E, D123K, S162C, K173I, Q174K, D177E, I178M, Q207S, L210M, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, N447S, D471E, Q480H, H483Y, L491S, A502V, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1296 CN1296 None None   E6D, V8I, K11T, K20R, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376T, K390R, K395R, A400T, E432D, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1299 CN1299 None None   E6D, K11T, V35T, E36G, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207N, R211N, K238R, V245E, K277R, T286A, E291D, R307K, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1301 CN1301 None None   P4T, E6D, K11A, V35T, T39K, K43E, K122E, D123S, K173R, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, T286A, E291D, I293V, E297K, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376T, K390R, K395R, A400T, T403M, E432D, N447S, S468P, D471E, Q480H, H483Q, L491S, K512R, L517I, Q524E, A534S, A554S  
CN1302 CN1302 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123N, K173I, Q174K, D177E, V179I, T200I, I202V, Q207A, R211S, V245E, T286A, E291D, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376V, E399D, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, L517V, S519N, Q524E, A534S, A554S  
CN1303 CN1303 None None  V179D E6D, K11T, V35T, T39K, K43E, V118I, D123N, E138G, I142V, K173I, Q174K, D177E, Q207A, R211S, F214L, V245E, A272G, T286A, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1310 CN1310 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123N, I135T, S162C, F171Y, K173R, Q174K, D177E, I178M, V179I, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, V317T, I326V, I329V, G335D, M357K, R358G, G359S, K366R, A371V, T377M, T386I, K390R, A400T, T403M, N447S, T470S, D471E, Q480H, L491S, V496I, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1313 CN1313 None None   E6N, K11T, V35T, K122E, D123S, S162C, K173I, Q174K, D177E, I202V, Q207N, R211S, K238R, V245E, A272P, T286A, E291D, V292I, I293V, L310I, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, D471E, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
CN1315 CN1315 None None   E6D, K11A, V21I, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200V, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, V466I, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1318 CN1318 None None   E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, I135T, T139A, S162N, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, F214L, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, I375V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1319 CN1319 None None   E6D, K11T, V35T, T39K, K43E, V60I, K122E, D123N, I142V, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E, K249R, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T377M, S379C, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1320 CN1320 None None   E6D, K11T, K32I, V35T, T39K, K43Q, D123N, S162C, K173I, Q174K, D177E, V179I, Q207K, R211S, K238R, V245E, I274V, T286A, E291D, V292I, I293V, E312N, I329V, G335D, M357K, G359S, K366R, A371V, A376T, K390R, A400T, T403M, E432D, N447S, Q464K, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1323 CN1323 None None   E6D, K11A, V35T, T39K, K43A, K122E, D123S, I135T, S162A, K173I, Q174K, D177E, I178M, T200A, Q207S, R211S, V245E, K277R, E291D, V292I, I293V, E297D, E312T, I326V, I329V, G335D, K350R, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, D471E, Q480H, L491T, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
CN1324 CN1324 None None   E6D, V35T, T39E, K122E, D123N, S162C, K173T, Q174K, Q207S, R211S, V245E, A272S, K281R, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, I375V, A400T, T403M, E432D, N447S, D471E, Q480H, H483Y, L491S, A502V, K512R, E514D, L517V, S519N, Q524E, A534S, A554S, I556V  
CN1326 CN1326 None None   E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123N, I135T, K173I, Q174K, D177E, I178V, T200I, Q207A, R211S, F214L, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1341 CN1341 None None   E6D, V35T, T39K, K43E, T69N, V106I, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, T200TA, Q207N, R211S, K238R, V245E, E248D, A272P, T286A, E291D, V292I, I293V, E312T, D324E, I326V, I329V, G335D, M357K, G359S, K366R, A371V, S379G, A400T, E432D, N447S, D471E, T477S, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, E529D, A534S, A554S  
CN1350 CN1350 None None   E6S, K11T, V35T, T39K, K43E, K122E, D123N, S162C, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E297V, E312T, V317T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T377M, K390R, A400T, T403M, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554T  
CN1351 CN1351 None None   E6D, K11T, V35T, T39K, K43E, V60I, D123N, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, E291D, V292I, I293V, E312T, V317T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, E399D, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1355 CN1355 None None   E6D, K11T, V35T, T39E, K122E, D123N, S162C, K173I, Q174K, D177E, Q207E, K238R, V245E, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376V, T386A, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, I505V, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
CN1379 CN1379 None None   V35T, E36Q, T39N, S48T, V60I, I135V, T139I, R199K, V245Q, A272P, K277R, E291D, V292I, I293V, V317A, G335D, R356K, G359T, T377I, K390R, A400T, E404D, E432D, V435A, L452M, Q464K, D471E, H483C, L484I, L491S, S519N, A534S, A554S  
CN1385 CN1385 None None   V8I, K20R, V35T, T39N, S48T, V60I, V245H, A272P, K277R, E291D, V292I, I293V, V317A, G335D, K347R, R356K, G359T, A360T, T377M, K390R, A400T, E404D, E432D, V435A, A437V, L452I, Q464K, D471E, H483C, L484I, L491S, S519N, K530R, A534S, A554S L26F 
CN1389 CN1389 None None   E6D, V35T, T39N, T69N, K122E, D123N, S162C, K173I, Q174K, D177E, I202V, Q207K, R211S, K238R, V245E, V276I, L283I, T286A, I293V, E312T, D324E, I326V, I329V, G335D, Y342F, M357K, R358G, G359S, K366R, A371V, T377K, V381I, K390R, K395R, A400T, T403M, E432D, V435I, N447S, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
CN1390 CN1390 None None   E6D, K11T, V35I, T39K, K43E, I50V, K102R, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, T200I, Q207A, R211S, K223E, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376T, K390R, K395R, A400T, T403M, E432D, N447S, T470S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
CN1394 CN1394 None None   E6D, V35T, T39A, K102R, K122E, D123N, S162C, K173I, Q174K, D177E, I202V, Q207S, R211S, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312T, L325I, I326V, I329V, G335D, E344D, A355G, M357K, R358G, G359S, K366R, A371L, T386I, K390R, A400T, T403R, E432D, N447S, D471E, Q480H, L491P, K512R, L517V, S519N, Q524E, A534S, Q547K, A554E, K558R  
CN1396 CN1396 None None   E6D, K11T, V35T, K43R, T69S, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, T200A, Q207K, R211S, K238R, V245E, A272P, K281R, T286A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, V435A, N447S, V458I, D471E, Q480H, H483Q, L491S, I505V, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
CN1402 CN1402 None None   V35T, T39E, S48T, V60I, D121Y, K122E, I135T, T200I, R211G, F214L, V245K, A272P, K277R, T286A, V292I, I293V, V317A, G335D, R356K, G359T, T377M, K390R, A400T, E404D, E432D, V435A, Q464K, D471E, H483C, L484I, L491S, S519N, K530R, A534S, A554S