<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Reigadas (2013)
Title HIV-1 integrase variability and relationship with drug resistance in antiretroviral-naive and -experienced patients with different HIV-1 subtypes.
Citation J Antimicrob Chemother
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 554
NumPts 554
Subtype B, CRF02_AG, A, G, C, D, F, CRF01_AE, CRF06_cpx, CRF09_cpx, H, A + CRF02_AG, J, CRF19_cpx, CRF18_cpx

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Page 1   from Isolate 1 to Isolate 100 from Total 554 Clinical IN Isolates

None    S17N, I72V, T218I, D256E  
10 10 None    K14R, S39C, L45Q, M50I, I72V, I113V, T124A, T206S  
11 11 None    D6E, E11D, E13D, L28I, V37I, S39C, S57N, I60M, S119P, T122I, T124A, V201I, T206S V281VM 
12 12 None    S39C, I72V, L101I, T122I, K156N, Y227F, S255N  
13 13 None    K14R, S17N, S24D, D25E, L28I, P30A, S39C, M50I, I72V, I113V, T124S, T125A, V201I, T206S, S230N, V249I P58PS 
14 14 None    L45V, I72V, K111T, S230SN, D232E, D256E S283G 
15 15 None    V31I, M50I, Y99F, L101I, K111KR, T124TA, G163E, V201I, S230N, D256DE S283SG 
16 16 None    S17N, I72V, I113IV, T124N, T125MV, M154I, S230N, D256DE  
17 17 None    E10D, T112I, I113V, T124N, T125A, T218I, D256E  
18 18 None    D3E, E11D, S17C, V32L, S39R, I72V, S119P, T125A, V201I, K211R, T218S, K219N, I220L, N222K S283G 
19 19 None    E11D, N27G, V32I, M50I, I72V, L101I, T112I, S119P, T122I, V201I, D256E  
None    V31I, V32I, I72V, T112A, T124N, T210N, A265V Y227N 
20 20 None    E11D, D25E, V31I, S39C, M50I, L101I, V201I, T206S, K215N, L234I  
21 21 None    M50I, T124A, A205S, D207E  
22 22 None    K34R, I72V, L101I, K211R, I217V  
23 23 None    E11D, A21T, I72V, Y99F, L101I, T124A, K211Q, S230N  
24 24 None    K34R, I72V, L101I, K211R, I217V  
25 25 None    E10D, A23V, L101I, T112I, I113V, T124A, T125A, D256E  
26 26 None    E10D, E11D, S39C, L101I, S119P, T122I, V201I, I217V, D253E  
27 27 None    D6E, E10D, E11D, S24N, V32I, S39C, L45I, M50I, L101I, K156N, T206S  
28 28 None    D6E, E10D, V31I, V32I, L74I, L101I, G163E, Q216H  
29 29 None    E11D, K14R, V32I, S39C, M50I, A91T, L101I, T125V, I135V, K136N, V201I, K240R  
None    S24A, L45V, M50I, I72V, T112M, S119P, K219N, N222K, P233Q  
30 30 None    S17N, V31I, I72V, S119G, T122I, T124A, T125A, V201I, S230N, D256E, A265V  
300 300 None    K14R, R20K, S39N, L101I, T112I, T124A, T125A, G134N, K136Q, S153A, E157Q, D167E, N222K, L234I, V249I S283G 
301 301 None    K14R, A21T, V31I, M50I, L101I, T112V, T124A, T125A, G134S, K136T, D167E, V201I, L234I A248V 
302 302 None    K14R, A21T, A23V, V31I, S39N, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, V165I, K173R, V201I, L234I S283G 
303 303 None    K14R, A21T, A23V, D25DE, V31I, S39N, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136QR, V165I, K173R, V201I, T206S, L234I S283G 
304 304 None    K14R, S17N, I72V, K111R, T112V, I113V, T124G, T125AP, G134N, K136Q, V201I, K211R, Q216H, T218S, L234I S283G 
305 305 None    E11D, K14R, S24N, V31I, A91T, E96D, L101I, K103R, T112V, S119R, T124N, T125A, G134N, K136Q, D167E, V201I, T206S, L234I S283G 
306 306 None   L74M V32I, L45V, M50I, I72V, T112I, K136Q, G163N, V165I, V201I, T218S, Y227F, L234I, S255N, D256E S283G, R284G, D288N 
307 307 None    S17N, D41N, K71R, L74I, I89M, A91S, L101I, T124S, T125A, A129X, K136Q, H171Q, K173R, G193E, V201I, T218I, L234V, D256E S283G, D286N 
308 308 None    K14R, S17N, V32I, L45Q, M50I, A98G, L101I, T124A, T125A, A133X, K136Q, V201I, T206S, Y227F, L234V, S255N, D256E, D270H S283G 
309 309 None    E11D, K14R, A21T, V31I, K34KR, M50I, V88I, L101I, T112V, T124AS, T125A, K127KR, G134N, K136Q, D167E, I208L, N222K, L234I, V260I I191IN, S283G 
31 31 None   V151I V31I, I72V, L101I, S119G, T122I, T218I, L234I, A265V  
310 310 None    S17N, V32I, L45LQ, M50MI, I72V, L101I, T112A, T125A, G134D, K136T, Q137H, F185FY, V201I, I203M, L234I, D256E, D270N S283G, D288N 
311 311 None    S17N, V31I, V32VI, D55N, I72V, L101IV, T112V, S119P, T124A, T125A, I135V, K136Q, K160KR, V165VI, K173KR, S195SN, V201I, T218L, K219N, N222K, L234I, D256E F100FV, S283G 
312 312 None    K14R, R20K, I72V, L101I, T112V, T124A, T125V, G134D, I135V, D167E, V201I, T218TI, S230SN, L234I, D256E, A265V S283G 
313 313 None   E138D S17N, G70GE, E87EK, T93TS, L101I, T112I, T125V, K136Q, G163A, K173KR, V201I, T206TS, E212EA, Y227F, L234V, D256E R107RK, S283G 
314 314 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, V126L, G134N, I135V, K136Q, D167E, V201I, L234I  
315 315 None    K14R, A21T, V31I, I72V, L101I, T112V, S119P, T122I, T124A, T125A, G134N, K136Q, D167E, I208L, Q221R, N222K, L234I R284G 
316 316 None    E11D, S17T, V31I, T112V, I113V, T124A, T125A, K136Q, I203M, I204V, K219N, N222K, L234I S283G 
317 317 None    K14R, A21T, S39C, M50R, I72V, L74I, G106A, T112V, S119T, T124A, T125A, V126M, G134N, K136Q, V165I, G193E, V201I, T206S, T210I, T218S, Q221E, L234I S283G 
318 318 None    Q9P, K14R, S17R, L74I, L101I, T112V, T124A, T125A, G134N, D167E, G193E, V201I, K211R, T218TI, Y227F, S230SN, L234I, N254K, S255G, I268IL H12P, H16P, P142PL, S283G 
319 319 None    S24N, V31I, L63I, I72V, L74I, K111KQ, T112MV, T124A, T125A, G134N, K136T, D167E, V201I, T206S, E212A, L234I, D256E S283G 
32 32 None    V31I, L101M, T112V, T124N, T125V, V201I, K215N, D256E, A265V  
320 320 None   Q146H E11Q, V31I, L101I, K111KR, T112V, T124A, G134D, K136Q, E157Q, K160Q, V201I, T218L, K219N, N222K, L234I, D256E  
321 321 None    K14R, V31I, T112V, T124A, T125A, K136Q, K160KR, D167E, V201I, I208L, K211R, L234I, V260VL I72LV, S283G 
322 322 None    E11D, K14R, V32I, L101I, T112I, T122I, T125A, G134N, K136T, V201I, T206S, K211R, E212I, Y227F, L234I, S255N, D256E S283G 
323 323 None   L74LIM E11D, K14R, V32I, L101I, T112I, T124TA, T125A, G134N, K136T, V201I, T206S, K211KR, E212AT, Y227F, L234I, S255N, D256E S283G 
324 324 None    E11D, A21T, A23V, V31I, V32I, D41N, M50I, I72V, L101I, T112V, T124A, T125A, G134D, K136Q, D167E, V201I, Q216N, L234I, S255D S283G, D288N 
325 325 None    K14R, A21T, V31I, S39N, I72V, Q95H, G106A, T112V, T124TA, T125A, V126L, G134N, I135V, K136R, V165I, V201I, L234I S283G 
326 326 None    K14KR, M50I, L101I, T112V, T124A, T125A, G134D, K136T, D167E, K173R, F181FL, V201I, L234I S283G 
327 327 None    K14R, V31I, L101I, G106A, T112I, T124A, T125A, G134D, K136Q, D167E, I208L, N222K, L234V, D256E S283G 
328 328 None    K14R, S24N, V31I, L101I, T112V, S119G, T122I, T124A, T125A, G134N, K136T, V165I, K173R, I182V, V201I, T206S, L234I, D256E S283G 
329 329 None    K14R, V32I, S39C, L101I, T112V, T124A, T125A, G134NS, I135V, K136T, V201I, T206S, L234I, N254K, V259VI, R269K S283G 
33 33 None    D25E, V31I, I113V, T124N, K188R, A196P, T206S, D256E S283G 
330 330 None    S17N, I72V, I113V, T124A, T125A, M154I, V165I R187T 
331 331 None    K14R, V31I, V32I, E48K, L101I, K111R, T112V, T124N, T125V, K136T, D167E, V201I, K219N, N222K, L234V, D256E  
332 332 None    E11D, K14R, R20K, A21T, A23V, V31I, I72V, L101I, T112V, T124A, T125A, G134N, K136Q, D167E, V201I, T210I, T218I, L234I E212~, S283G, D288N 
333 333 None    K14R, S17N, S39N, I72V, L74I, R107X, T112V, T124A, T125A, G134D, K136Q, V201I, A205S, T218S, Q221H, N222K, L234I, D256E V281M 
334 334 None    K14R, A21T, V31I, D41DN, I72V, L101I, T112V, T124A, T125V, G134N, K136Q, V165I, D167E, I208L, T218I, L234I S283G 
335 335 None    K14R, A23V, S24N, V31I, D41S, M50I, I72V, L101I, T112V, I113V, T124A, T125A, G134D, K136Q, D167E, E170K, V201I, T206S, L234I S283G, D288N 
336 336 None    V31I, L74LI, L101I, G106GA, T112M, S119SAGT, T122TI, T124A, T125A, G134N, D167E, V201I, T206S, D207E, K211Q, E212A, T218L, K219Q, Q221QK, L234I S283G, D286N 
337 337 None    K14R, V31I, S39N, M50I, L101I, T112V, T124N, T125A, G134N, I135V, K136T, V165I, V201I, T206S, Q216H, L234I, D256E S283G 
338 338 None    K7R, K14R, A21AT, S24SN, S39C, I72V, L101I, T112AV, T124A, T125A, G134N, K136Q, D167E, V201VI, I208L, Y227F, L234V S283G 
339 339 None    K14R, A21T, S39C, M50I, I72V, I84M, L101I, G106A, T112V, T124A, T125V, G134N, K136Q, D167E, V201I, I208L, Q221T, N222T, L234I S283G, D286V 
34 34 None    S17N, I72V, S119P, T124A, Q209P, Q221K, N222K, S230N R284G 
340 340 None    S17N, D25E, P30A, V32I, L45V, G59E, L101I, T112R, T124S, T125A, K136Q, V201I, T206S, T218I, L234V, D256E, R269RG D279GS, S283G 
341 341 None    K14R, S17N, D25DE, V31I, M50MI, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, G163GE, D167DE, V201I, T206S, L234I S283G, D288N 
342 342 None    K14R, R20RK, V31I, K34R, S39SN, S57SN, E96D, L101I, K103KR, K111KR, T112V, S119R, T124S, T125A, K136T, D167E, V201I, T206S, Q216N, L234I, D256E, D270DN, M275MV S283G 
343 343 None    E11D, S24N, I84IM, L101I, T112V, T124A, G134N, K136T, V201I, I208L, L234I, D256E S283G 
344 344 None    E11D, K14R, A21T, V31I, D41N, S57R, I72V, L74I, A91T, T112V, T124A, T125A, G134N, K136Q, I182V, V201I, L234I S283G 
345 345 None    D6E, R20K, I84M, L101I, T112V, T124A, T125A, G134N, K136T, H171Y, V201I, I208L, L234I, A265T K14E, S283G 
346 346 None   T97A S17N, M50I, L101I, T112I, T124A, T125A, I135V, K136Q, V201I, K211KR, L234I, D256E S283G 
347 347 None   L68I K14R, A21T, A23V, V31I, S39N, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136Q, D167DE, V201I, T206S, Q221T, L234I A98AE, S283G 
35 35 None    K34R, M50I, I220M  
36 36 None    I72V, S119G, T122I, T125A, V201I  
37 37 None    D25E, M154I, K188R, V201I, T218I, L234V  
38 38 None    E11D, T112V, V201I, T206S, E212A, K219Q S283G 
39 39 None    D6N, K7Q, E11D, S17T, A23V, Y99F, L101I, K111T, S119A, T124N, T125A, I135V, K211R  
None    M50I, I72N, L101I, V201I, K215N, T218I, S230N  
40 40 None    E10D, V31I, M50I, I72V, S119P, T122I, T124A, T206S, A265V  
41 41 None    S17N, M154I, V201I  
42 42 None    E10D, I72V, S119G, T122I, T124A, T125A, V201I, T206S  
43 43 None    L45V, L101I, T122I, T124G, T125A, F181L, I208L, T218I  
44 44 None    S17N, I72V, L74I, S119T, T124A, T125A, E157Q, K160Q, G193E, V201I, D207N, K211T, D256E R284G, D288N 
45 45 None    E11D, S17T, M50T, L101I, T124N, T125V, G163E, E212A, D256E  
46 46 None    E10D, V31I, M50I, I72V, L101I, S119P, T122I, T124A, K160Q, G163N, I208L, N222H, D253E, N254G D286N 
47 47 None    E11D, S17T, K111T, S119P  
48 48 None    I72V, T124A, T125V, E198D, V201I, K215N, N222H  
49 49 None    K14R, R20K, S57G, I72V, L101I, T124A, T125A, G134N, I135V, K136T, G149A, V201I, T206S, Y227F, L234I, S255N S283G 
None   E138D E11D, M50I, I60V, I72V, K111T, S119G, T122I, V126M, T206S, I208M  
50 50 None    V31I, I72V, K111T, T124A, D167E, S230N  
51 51 None    K7R, I72V, L74I, K111Q, I113V, T124A S283G 
52 52 None    E11D, S24N, L101I, K173R, I200M, I208F, D229E  
None    K7R, E11D, V32I, I72V, K111T, T124N, V201I, A205S, T218S  
None    K7R, E11D, A21T, I72V, L101I, T124A, T125A, I135IV, A205T, T206S P142PS 
None    S24G, D25E, L45V, T112A, T125A, K160R, I220V, D232E, N254K  
None    E11D, V31I, S57G, K111T