<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Kousiappa (2011)
Title Molecular characterization of HIV type 1 strains from newly diagnosed patients in Cyprus (2007-2009) recovers multiple clades including unique recombinant strains and lack of transmitted drug resistance.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 74
NumPts 74
Subtype B, A, C, CRF02_AG, F, CRF37_cpx, CRF11_cpx


Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
CY181 CY181 None None   K122E, I135T, G196E, L260I, I293V, P294Q, D324E, Q334E, R356K, I375M, K390R, A400T, T403A, R461K, V467I, Q480E, Q520K, K527N, A554T  
CY182 CY182 None None   K20R, V35T, T39M, V60I, K122E, D123N, I135T, K173Q, Q174K, I178M, V179I, Q207A, R211S, V245R, D250E, K281R, T286A, E291D, I293V, P294T, E297K, G335D, R356K, M357K, G359S, K366R, T369A, A371T, I375V, T377M, A400T, T403M, E404D, E432D, N447H, D471E, Q480H, L491S, Q509H, K512R, S519N, Q524E, K527R, E529D, A534S, A554S  
CY184 CY184 None None  V179E K32R, V35L, S48T, D123E, F214L, D237E, K277R, A288S, V292I, I293V, R356K, R358K, A376T, T377L, T386I, K390R, A400T, T403M, V435I, L452S, V458I, K476R, H483Y D177DGNS 
CY185 CY185 None None D67N, K70R, M184V, T215Y, K219E, N348I Y181C K11A, V35T, K122E, D123N, T139R, I142V, K173T, Q174K, D177E, T200A, Q207A, V245E, E248D, T286A, V292I, I293V, P294T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, A376T, E399N, A400T, T403V, E432D, A455S, R461K, D471E, T477A, Q480H, H483Y, K512R, S519N, Q524K, K527E, A534S, A554S  
CY187 CY187 None None   V35T, E36A, T39E, S48T, V60I, K102Q, D123E, K173V, Q174K, D177E, V179VA, G196E, T200A, E203D, Q207D, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, I326V, Q334D, R356K, G359T, T377L, S379C, K390R, A400T, E432D, L452M, V466I, T470S, D471E, T477A, Q480H, H483L, L484I, A485G, Q487P, D488A, G490R, L491S, S519N, K530R, V531I, A534S, A554K  
CY188 CY188 None None   K11Q, K49R, R83K, D121H, I135T, A158AS, S162SC, E169D, Q207D, L210LM, R211K, I293V, E300K, E328K, I329V, Q334L, G359S, A371V, V435M, R461K, S468T, I556V  
CY189 CY189 None None   V118VI, I135IRT, S162ST, T165TI, E169ED, Q174K, T200TA, I202V, F214FL, T286A, E297A, E328K, Q330P, K331N, Q332K, M357T, A376T, T386I, A400T, T450S, T470N, H483Y, Q524E, V531I, A554T  
CY190 CY190 None None   K104KR, R211K, V292I, I293V, S322T, K390R, E399D, E449D, D460N, R461K, S468N, Q524E, A554T, K558R Q269Q_INWASQ 
CY191 CY191 None None   K20KR, V35T, T39L, K49R, K101KQ, D123E, S162C, E169D, K173A, I178L, E204Q, Q207A, P243Q, V245Q, E248D, S251I, A272S, T286A, A288T, E291D, V292I, I293V, P294T, E297A, V317A, A327G, E328K, I329T, Q330P, I341F, R356K, M357R, G359S, T369A, A371V, T377M, K390R, A400T, T403M, E432D, V458I, R461K, D471E, Q480H, H483W, L491P, K512R, L517I, S519N, Q524K, K527E, A534S, A554S  
CY192 CY192 None None   K11S, V35T, T39A, V60I, K104R, K122E, D123S, I135T, K173A, D177E, T200A, Q207EG, R211K, F214L, V245Q, E248D, K281R, E291D, V292I, I293V, P294T, E297K, S322E, D324E, G335D, R356K, M357R, G359S, K366R, T369A, A371V, K374R, I375V, A376T, K390R, A400T, T403M, A446S, V467I, D471E, T477A, Q480H, G490E, K512R, L517V, S519N, Q524K, K527E, K530R, A534S, A554S  
CY194 CY194 None None   K104R, R211K, V292I, I293V, S322T, R356K, K390R, E399D, E449D, D460N, R461K, S468N, Q524E, A554T, K558R  
CY195 CY195 None None   K122E, I135T, S162C, K201KR, E203EV, R211K, V245Q, K277R, T286A, P294T, E297Q, D324E, Q334L, R358K, A360T, K390R, T403M, D460N, R461K, S468T, Q480H, H483Y, E516D, S519N, V531I, A554T Y354C 
CY196 CY196 None None   V35T, K49R, V60VI, K122E, D123N, I135T, K166KR, E169D, F171Y, K173S, Q174K, D177E, V179I, T200A, I202V, Q207S, V245K, D250E, A272P, Q278E, K281R, T286A, I293V, E298G, E312D, V317A, Q334L, G335D, P345Q, M357K, G359S, A360T, K366R, T369V, A371V, I375V, A376V, A400T, T403M, E404D, W410L, E432D, V435A, D471E, Q480H, L491S, K512R, S519N, Q520L, K527G, E529D, A534S, A554S, K558R, V559I  
CY197 CY197 None None   V35I, R83RK, K103R, D121DH, K122E, I135T, S162C, T200A, I202V, Q207E, V245E, A272P, K281R, T286A, P294S, I329V, L452I, D460N, R461K, L469I, H483Y, A554S E224EV 
CY198 CY198 None None   V60VI, K82R, R83K, I135T, I178L, R211K, K277R, I293V, I326V, I329L, V365I, V381I, V435I, S468P, A554S, I556V  
CY199 CY199 None None   G18X, K20R, V35VI, I142IT, Q197H, V245E, K277R, I329L, M357T, T377L, V435G, V458I, V466I, V467I, L491A, K527H, K530R, A534T, V548I, D549N, A554T  
CY200 CY200 None None   V35M, T39A, S48E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q, E248D, A272P, E297A, S322T, I326V, Q334P, G335D, R356K, M357R, G359S, T369A, I375V, A376T, S379C, K390R, A400S, E432D, D471E, Q480H, H483Y, L491S, Y501D, A534S, V548I, A554S, K558R  
CY201 CY201 None None   V35T, D123E, S162H, Q174N, D177E, G196E, R211K, A272P, I293V, K311R, Q334L, F346C, K366R, A376S, E399D, L491S, Q500R, A554T, K558R  
CY202 CY202 None None V75VL  K82R, V106VI, V118I, D121H, K122E, S134SC, I135T, T139A, Q174QK, D177E, I178L, I180L, G196E, F214L, V245I, A272S, T286A, A288S, E297A, V317A, R356K, M357T, A376V, T386M, A400T, K512Q, S519R, K527N C38CW 
CY203 CY203 None None   V35T, T39E, S48T, V60I, V118I, K122A, D123NS, I135T, E138A, T139A, K173A, Q174R, D177E, V179VI, G196GE, T200A, R211KQ, F214L, V241I, V245Q, A272S, K277R, T286A, E291D, Q334N, G335D, R356K, G359T, T377L, V381I, K390R, T403A, E404D, V435A, L452M, S468P, D471E, H483Y, L491S, S519N, K527Q, K530R, A534S, D549N, A554N Q207*DEY, Q269Q_INWASQ 
CY204 CY204 None None   S48T, V60I, D123E, I135T, G196E, R211K, V245VM, K277R, I293V, E297A, K347R, A376S, K390R, Q394N, V435A, G436R, R448T, S468P, H483Y, A502G, Q520P, G544R P236PR 
CY205 CY205 None None   V35T, E36A, T39E, S48T, E53ED, K104R, K122E, S162Y, K173A, D177E, I178M, I195L, G196E, T200A, E204K, Q207E, P243T, V245Q, A272P, K275R, Q278H, K281R, T286A, E291D, V292I, I293V, G333E, Q334H, G335D, R356K, M357R, G359T, T377R, T386I, K390R, E399D, A400S, E404D, L422I, V435A, S468T, D471E, H483Q, L491S, E492K, S519N, K527N, E529D, A534S, V548A, A554S  
CY206 CY206 None None   V35T, K43KN, K49R, I135V, S162A, K173T, Q174K, D177E, T200AV, Q207E, R211RK, V245Q, E248D, T286A, E291D, V292I, I293V, P294I, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, T377I, T403M, E432D, V435L, G436E, V467I, D471G, T477A, Q480H, H483Y, D488E, L491S, E514D, S519N, Q520L, Q524K, K527E, E529D, A534S, A554N  
CY207 CY207 None None   V35T, V60I, K102Q, K122E, D123N, S134SR, K173G, Q174K, D177E, V179I, Q197L, T200A, Q207A, R211N, D237DE, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, P294T, S322T, G335D, I341F, M357K, G359S, T369A, A371V, I375M, A376S, T377M, K390R, A400T, T403R, E404D, E432D, D471E, Q480H, L491S, K512R, S519N, Q524K, K527G, E529D, A534S, A554S, I556V P25PS 
CY208 CY208 None None   K20R, V35T, V60I, D121H, K122E, I135T, S162C, K173S, Q174K, D177E, I178L, V189VI, T200A, Q207A, R211S, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, P294T, G335D, M357K, G359S, A371V, I375V, A376G, T377L, A400L, T403M, E404D, E432D, V435M, G436R, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, A534S, A554T, I556V, K558R  
CY209 CY209 None None   K20R, V35T, V60I, K101R, D121H, K122E, I135T, S162C, K173S, Q174K, D177E, I178L, T200A, Q207A, R211S, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, P294T, G335D, M357K, G359S, T369A, A371V, I375V, T377M, K388R, A400L, T403M, E404D, E432D, V435M, R461T, D471E, Q480H, H483Y, L491S, K512Q, S519H, Q524K, K527G, E529D, A534S, A538P, H539P, K540Q, A554T, I556V, K558R  
CY212 CY212 None None   E6D, V35T, T39A, K49R, D123E, S134C, I135V, S162C, P170S, K173T, Q174K, D177N, T200I, Q207E, R211K, V245Q, E248N, A272P, T286A, E291D, V292I, I293V, E297T, I329L, R356K, G359T, T377M, Q394L, E399D, A400T, Q428H, K431T, V435A, A446S, L452Q, R461K, V466A, D471E, T477A, H483K, A554T  
CY213 CY213 None None A62V  K11T, V35I, E36D, T39E, K82KR, K122E, D123NS, I135T, A158AS, K173L, Q174K, D177E, T200TA, Q207AT, R211RS, V245M, E248D, A272P, T286A, E291D, V292I, I293V, P294T, I326V, R356K, M357K, R358G, G359S, E370A, A371V, I375V, V381I, K390R, T403M, L452M, S468P, D471E, Q480H, L491S, K512S, L517V, S519N, Q520K, Q524K, K527E, K530R, A534S, A554N, K558R  
CY214 CY214 None None   K122KE, Q145C, T200TS, R211RK, F214FL, D250DE, T286P, V292I, E297A, S322T, M357T, A376T, I393M, A400T, T470N, H483Y, K512R, E516D, L517I, A554S, I556V, K558R  
CY216 CY216 None None   P55A, V60I, V118I, S134C, I135T, T139R, S162A, R211K, F214L, V245E, D250E, A272P, K277R, K281R, T286P, A288S, E297R, G333E, Q334K, G335S, M357T, T386I, K390R, A400T, V435I, D460N, V467I, S468P, Q480H, S519N, K527N, A554T  
CY217 CY217 None None   K20R, V35T, E36D, T39V, K122E, D123G, I135V, Q145R, S162A, K173A, Q174K, D177G, T200I, Q207A, R211S, V245L, T286A, E291D, I293V, S322T, I326V, G335D, R356K, M357R, G359T, T369A, A371V, I375V, T377I, K390R, K395R, A400T, T403M, T409S, E432D, V435A, T450N, V458I, D471E, Q480H, L491S, K512R, S519N, Q520L, Q524E, K527G, E529D, A534S, A554N R143E, Y144C 
CY218 CY218 None None   V35T, E40D, K49R, V60I, K122E, K173S, Q174K, D177E, V179I, T200A, Q207A, R211K, V245H, D250E, E291D, V292I, I293V, P294T, G335D, M357K, G359S, K366R, A371V, I375V, A376V, T377M, E399D, A400T, T403M, E404D, E432D, V435A, K454R, D471E, Q480H, H483Y, L491S, L517I, S519N, Q524K, K527G, E529D, A534S, A554S  
CY219 CY219 None None  E138EAKT E6K, V35T, T39G, S48T, K103R, V118VI, K122E, D123DN, S162C, K173AT, N175NH, T200A, K201KR, Q207E, R211K, F214FL, V245Q, A272P, K277R, T286A, I293V, G335D, R356K, M357R, G359T, A376V, T377M, T386A, A400T, E432D, G436E, L452I, V466I, S468T, T470N, D471E, T477A, H483Q, L491S, S519N, K527N, K530R, A534S, A554S  
CY220 CY220 None None   V35M, T39A, D123E, I135V, D177E, G196E, Q207E, L210F, R211K, V245M, E248D, A272P, I293V, V317A, Q334L, A360V, T369A, K374R, I375V, K390R, Q394L, E399D, V435I, V458I, V548I D185DA 
CY221 CY221 None None   V35T, E36EA, T39E, S48T, V60I, D121H, K122E, D123DGNS, K173T, Q174K, D177E, I178IL, T200A, L205LF, Q207E, R211K, K223KR, M230MR, D250DE, A272P, K277R, T286A, E291D, V292I, I293V, Q334N, G335D, R356K, G359T, T377M, K390R, A400T, E404D, L429W, V435I, A446S, V466I, D471E, H483Q, L491S, S519N, K527N, K530R, A534S, A554S, K558R  
CY222 CY222 None None   V35T, D123E, I135L, K173V, Q174K, T200I, Q207A, R211K, V245Q, E248D, A272P, V276I, K277R, T286A, E291D, V292I, I293V, E297A, I326V, F346C, R356K, G359S, A376V, T377Q, T386I, E396K, W402*, T403I, E404D, K431T, V435T, A446S, L452I, D471E, T477A, L491S, Q524R, K527Q, A534S, G543R, A554N, V559I E302K 
CY223 CY223 None None   V35T, T39N, K43E, D121H, K122E, I135T, E169D, K173A, Q174K, D177E, I178M, T200A, I202V, Q207N, R211K, V245Q, E248D, L283I, I293V, P294T, V317A, S322A, I326V, G335D, F346H, R356K, M357R, G359S, V365I, K366R, T369V, T377Q, S379G, T386V, K390R, T403M, K431R, V435A, R461K, T470N, D471E, Q480H, H483Y, L491S, K512R, A534S, A554N  
CY224 CY224 None None   K11Q, V35L, S68G, A98S, I135R, T200A, R211K, I293V, I326V, I329V, Q334E, K390R, E399D, T403M, V435E, A446S, S468P  
CY225 CY225 None None M184KRT  V35VI, S48T, V60I, K122E, D123E, I135RT, T139TAIV, E169D, K173R, D177DE, G196E, Q207E, R211K, A272P, K277R, A288S, E297A, K311R, D324E, R356K, K366R, A376S, K390R, E404D, H483Y, E492K, I522V, K527N, K530Q, I556V, K558R  
CY226 CY226 None None   K11KR, D123E, I135V, Q145IV, S162A, K173T, A272P, I293V, D324E, P345Q, K390R, A400T, V435A, A446S, V467I, H483Q, V496I, K530R, A554N, V559I N265D 
CY227 CY227 None None   K20KR, V35T, T39TAEK, K122E, D123S, I159IV, T165TI, K173A, Q174K, D177E, T200A, Q207E, R211RK, F214L, V245K, D250E, A272P, K277R, E291D, I293V, P294S, Q334H, G335D, R356K, G359T, V365I, A376S, T377M, K390R, A400T, E404D, E413D, L452I, R463K, V466I, V467I, D471E, H483Q, L491S, A508G, E516D, S519N, K527R, K530R, A534S, A554K  
CY228 CY228 None None   V35T, T39E, K102KR, K122E, D123S, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245K, D250E, A272P, K277R, E291D, I293V, P294S, L310I, Q334H, G335D, R356K, G359T, V365I, A376S, T377M, K390R, A400T, E404D, E413D, L452I, R463K, V466I, V467I, D471E, H483Q, L491S, A508G, E516D, S519N, K527R, K530R, A534S, A554K A98AV 
CY229 CY229 None None   V35T, T39M, K101Q, K104R, K122E, D123E, I135T, S162C, Q174QR, D177DN, V179I, I195L, R211RK, V245E, I293V, P294A, E297K, K311R, Q334D, M357R, G359S, T377L, K390R, I434V, V435A, D460N, Q480H, H483Y, I506L  
CY230 CY230 None None   K20R, V35K, T39A, V60I, K122E, I135T, I142T, T165I, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, V245Q, D250E, T286A, E291D, V292I, I293V, P294T, S322A, A327V, G335D, M357K, G359S, T369A, A371V, I375V, A376V, T377M, K390R, A400T, T403M, E404D, E432D, V435E, D471E, Q480H, L491S, K512S, E514D, L517I, S519N, Q524K, K527G, E529D, A534S, A554N  
CY231 CY231 None None A62V  K11T, V35I, E36D, T39E, V118I, K122E, D123S, I135T, A158S, K173L, Q174K, D177E, T200A, Q207A, R211N, V245M, E248D, A272P, T286A, E291D, V292I, I293V, P294T, I326V, R356K, M357K, R358G, G359S, E370A, A371V, I375V, V381I, K390R, T403M, L452M, S468P, D471E, Q480H, L491S, K512S, L517V, S519N, Q520R, Q524K, K527E, K530R, A534S, A554N, K558R  
CY232 CY232 None None   A98S, D123E, E138A, I142V, K173R, Q207L, R211K, V245E, A272P, T286A, P294S, E297K, L310I, G333E, V365I, A376S, S379G, T386I, D460N, K465R, H483Y, A534T, A554T  
CY235 CY235 None None   K20R, V35T, V60I, K102KQ, V118VI, D121H, K122E, I135T, S162SC, E169EA, K173A, Q174K, T200A, Q207A, R211K, V245Q, E248ED, D250E, T286A, E291D, I293V, P294T, K311R, I329L, G335D, M357N, G359S, T369A, A371V, I375V, T377L, K390R, A400L, T403M, E404D, E432D, V435A, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, A534S, A554S, K558R  
CY236 CY236 None None   K20R, V35T, V60I, D121H, K122E, I135T, S162C, E169A, K173S, Q174K, T200A, Q207A, R211K, V245Q, D250E, T286A, E291D, V292I, I293V, P294T, E300K, K311R, D324E, I326V, G335E, M357K, G359S, T369A, A371V, T377M, A400L, T403M, E404D, E432D, V435A, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, V531I, A534S, A554T, K558R  
CY237 CY237 None None   E6D, S162C, R211Q, A272T, K277R, E291D, E297A, T338S, R356K, E370D, T377L, K390R, E399D, T403M, S468P, H483Y, L491V, Q524A, V531I, A554T  
CY238 CY238 None None   D123E, E138A, S162C, I202V, R211K, K277R, T286A, A288S, V317A, R356K, K366R, K390R, T403M, V435I, R463K, H483Y, G490E, L491S, K527Q, A554T, I556V, K558R  
CY240 CY240 None None   V35T, T39L, K43R, V60I, K102Q, I135KR, S162AT, K173A, Q174K, P176L, D177E, I178M, T200A, Q207E, R211K, V241VI, V245E, D250E, K281R, T286A, E291D, I293V, E297K, S322T, I326V, G335D, R356K, M357R, G359S, T369A, A371V, I375A, T377L, V381I, K390R, Q394T, A400T, T403M, E432D, T470N, D471E, Q480Y, H483Q, L491S, E492Q, Q509H, K512R, L517M, S519N, Q524K, K527E, E529N, A534S, A554S  
CY241 CY241 None None   R83K, I135T, T165I, D177DN, T200A, Q207E, V245E, K277R, I293V, E297Q, I329L, A376V, T386I, E399D, A400T, T439X, A446L, N447X, K451N, S468P, T473P, I482V, H483Q, L491S, E492Q, A502V, I506L, S519N, A534T, K558R F440d, Y441d, V442L, A445L 
CY242 CY242 None None   D123E, I142V, T165I, I178L, R211K, V245K, K277R, T286A, I293V, E297K, Q334E, S379G, K390R, E404D, V435L, L452S, S468P, H483Q, L491S, L517I, S519N, K527N, A554S  
CY243 CY243 None None   V35T, V60I, K102Q, D121H, K122E, I135T, S162CG, T165TI, K173ST, Q174K, D177E, I178IL, V179VI, T200A, Q207A, R211S, V245EQ, D250E, A272P, T286A, E291D, V292I, I293V, S322A, G335D, M357K, G359S, T369A, A371V, I375V, T377M, K390R, A400L, T403M, E404D, E432D, V435M, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, A534S, A554T, I556V, K558R  
CY244 CY244 None None   V35I, R83RK, D123E, S162C, D177E, I178L, I195L, R211RG, E224D, A272P, T286A, A288G, V292I, I293V, Q334E, M357T, V365I, A376S, K390R, K395R, E399D, A400S, D460N, V467I, S468P, L491S  
CY246 CY246 None None   P55A, V60I, V118I, S134C, I135T, T139R, S162A, R211K, F214L, V245E, D250E, A272P, K277R, K281R, A288S, V292I, E297R, G333E, Q334K, G335S, M357T, G359S, T386I, K390R, E399D, A400T, V435I, D460N, V467I, S468P, Q480H, S519N, K527N, A554N  
CY247 CY247 None None   V35T, E36D, T39L, V60I, S68G, V90I, T107S, K122P, I135V, E138A, T139I, S162A, Q174N, D177E, I178V, Q197L, Q207E, R211K, V245Q, A272P, T286A, E291D, V292I, I293V, P294T, E297D, L310I, S322A, I326V, G335D, R356K, M357R, G359S, K366R, T369A, A371V, T377I, K390R, K395R, T403M, E432D, V435I, R461K, D471E, Q480H, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554N  
CY250 CY250 None None T215TI, K219KE K103KN E6EK, D123DE, I135IT, I178L, I244IV, S322N, I326V, I329L, A360T, K390R, K431N, S468P, L484I, A554S  
CY251 CY251 None None   K20R, V35I, K122E, I135M, I142IM, R211K, F214L, T286A, I293V, P294S, L295F, E297K, A371V, A376V, A400T, R463K, T497S, Q524E, K530R, A534T, A554T, K558R  
CY252 CY252 None None   V35T, T39K, K122E, D123N, I142V, S162A, K173T, Q174K, D177E, T200E, E203Q, Q207E, F214L, V245EK, E248ED, T286A, I293V, P294T, S322A, G335D, R356K, M357R, G359S, E370D, A371V, I375V, A376V, K390R, T403M, S468T, D471E, Q480H, H483C, L491S, E516Q, S519N, Q524K, K527E, E529D, V531I, A534S, A554S  
CY253 CY253 None None   K20R, K103R, K122E, D123E, I135T, T165I, D177E, T200A, V245MT, A272P, I293V, P294S, D324E, K347R, T386V, T403V, S468P, A554K, K558R  
CY254 CY254 None None  K103N V106I, I135T, R211K, F214L, L283I, A288T, I293V, P313S, V317A, E328D, M357T, I375V, T377L, K390R, E449D, K512R, K527Q, A554S  
CY255 CY255 None None   K11T, V35T, E36D, T39M, K122E, D123S, I135T, S162SN, K173A, Q174RS, D177E, T200I, Q207A, R211S, V245E, E248D, D250DGNS, A272P, V276I, K277R, T286A, E291D, V292I, I293V, P294T, D324E, I326V, G335D, R356K, M357R, R358G, G359S, E370A, A371V, I375V, A376T, T377M, K390R, T403M, V435A, L452A, S468P, D471E, Q480H, L491S, K512R, L517I, S519N, Q520K, Q524K, K527E, K530R, A534S, A554Q  
CY256 CY256 None None   K20R, V35T, E36D, T39L, D123E, I135V, S162A, F171Y, K173T, Q174K, D177E, T200A, E203EK, Q207DEG, R211RK, P243H, V245Q, T286A, E291D, V292I, I293V, P294T, T296S, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, T377L, K390R, K395R, T403M, E432D, V435P, R461K, S468T, D471E, Q480H, L491S, K512R, S519N, K527G, E529D, A534S, A554S  
CY257 CY257 None None   S48T, K49R, V60I, K64R, V90I, K122E, D123E, E169D, K173R, G196E, Q207E, R211K, A272P, I293V, E297A, D324E, R356K, K366R, A376S, K390R, E404D, H483Y, E492K, I522V, K527N, K530Q, I556V, K558R  
CY258 CY258 None None   E28K, K32E, I135T, T139TS, I142IMT, S162C, R211K, K249KQ, D250DANT, S251SC, K277R, T286A, V292I, I293V, E297A, V317A, K390R, V435A, S468P, T470A, H483N, I556V  
CY259 CY259 None None   E6DN, V35T, T39L, K43R, D123N, T165I, K173T, Q174QK, D177E, T200E, I202V, Q207E, F214L, V241I, V245Q, E248D, D250E, S251C, A272S, L283I, E291D, V292I, I293V, E297A, S322E, I329V, G335E, R356K, M357R, G359T, K366R, T386I, K390R, A400T, E404D, V435I, E449N, L452I, R461K, S468T, D471E, Q480E, S519N, K527S, A534S, A554S  
CY260 CY260 None None   P4S, V35IT, E36D, T39E, S48ST, K122E, D123DG, E138A, S162C, K173A, T200AE, Q207GR, R211K, V245Q, D250E, A272P, K277R, E291D, V292I, I293V, Q334E, G335D, R356K, M357V, G359T, T377K, S379C, K390R, A400T, E404D, V435A, E449D, L452I, V458I, V466I, T470N, D471E, H483Y, L491P, E516G, K527Q, K530R, A534S, V548I, A554S  
CY262 CY262 None None D67N, K70R, K219Q  V90I, I135T, R211K, F214L, K277R, T286A, E297A, E328K, A360V, A376T, G384E, K390R, A400T, E415K, E430K, K451R, D460N, T473P, G490R, E492K, G504*, S519N, Q520H, Q524H, A554N E89K 
CY263 CY263 None None   K20R, V60I, I135K, T139S, Q145C, S162Y, I178M, T200A, Q207D, R211K, A272P, V276I, V292I, I293V, E297A, I326V, I329V, Q334E, V365I, A376G, T403M, E404D, E438K, T450N, L452S, T470A, H483Y, L517I  
CY265 CY265 None None   I31M, V35T, T39*, K43R, V60I, K102Q, I135R, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K, V245E, D250E, K281R, T286A, E291D, I293V, E297K, S322T, I326V, G335D, R356K, M357R, G359S, A360T, T369A, A371V, I375A, T377L, V381I, K390R, Q394T, A400T, T403M, E432D, V467I, T470S, D471E, Q480Y, H483Q, L491S, Q509H, K512R, L517M, S519N, Q524K, K527E, E529N, A534S, A554S  
CY266 CY266 None None   E6D, V35I, R83K, K122P, S162C, D177E, I178L, R211K, A272P, T286A, P294T, E297R, Q334N, K390R, A400T, V435L, L452I, D460G, T470S, I495V, V496I  
CY267 CY267 None None   P55A, V60I, V118I, S134C, I135T, T139R, S162A, R211K, F214L, V245E, D250E, A272P, K277R, K281R, T286P, A288S, V292I, E297R, G333E, Q334K, G335S, M357T, A376S, T386I, K390R, E399D, A400T, V435I, D460N, S468P, Q480H, S519N, K527N, I556V  
CY268 CY268 None None   T200I, R211K, A288S, V292I, I293V, S322T, K390R, E399D, R448K, E449D, L452V, R461K, S468N, E492K, I495V, Q524E, A554T, K558R