<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Oliveira (2012)
Title Genetic diversity and naturally polymorphisms in HIV type 1 integrase isolates from Maputo, Mozambique: Implications for integrase inhibitors.
Citation ARHR
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 57
NumPts 57
Subtype C, A, J, CRF02_AG, CRF01_AE, G


Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
GA01 GA01 None    K14KR, D25E, V31I, I72V, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, A265V, R269K, D278A S283G 
GA02 GA02 None    K14KR, D25E, K34R, M50I, F100Y, L101I, T112V, T124A, T125A, K136Q, G193E, V201I, T218I, R224Q, L234V, S255N, D270N, D278A, D279G Y271YC, S283G 
GA03 GA03 None    V31VI, K34KR, M50MI, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218TI, L234I, N254K, D270DE, D278A K127KQ, V281M, S283G, R284G 
GA04 GA04 None   L74LIM E10ED, E11ED, K14R, S24N, V31I, I60V, I72V, F100Y, L101I, T112V, S119P, T124A, T125A, K136Q, F181FL, K188KR, G193GR, V201I, I203IM, I208IL, T218L, K219KN, N222NK, L234I, A265V, I268IL, R269RK, D278A S283DG 
GA05 GA05 None   G140R D25E, V31I, M50I, G59R, G70R, I72V, F100Y, L101V, G106R, T112V, S119P, T124A, T125A, V126L, G134S, K136Q, G149R, R166K, V201I, T206S, I220V, R224Q, L234I, I251L, A265V, R269K, G272R, D278A G52R, S283G 
GA06 GA06 None    E11D, S24G, D25E, V31VI, F100Y, L101I, T112V, T125A, K136Q, V201I, T206S, K211R, T218I, K219Q, L234I, A265V, D278A S283G 
GA07 GA07 None    D6DE, E10ED, E11ED, K14KR, A21AT, D25E, V31I, M50I, I72V, F100Y, L101I, T112IV, T124A, T125A, K136Q, V201I, T218TIM, L234I, A265V, R269RK, D278A S283G 
GA08 GA08 None    E11D, D25E, F26Y, V31VI, V37I, I72V, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, M275MV, D279G S283G 
GA09 GA09 None    D25E, V31I, M50I, H51HQ, I72V, L101I, T112V, T124A, T125V, K136Q, D167DE, V201I, K211KR, T218K, L234I, A265V, R269K, D278A S283G, R284G, D288N 
GA10 GA10 None    D6E, E10D, D25E, V31I, L45M, I84M, A91T, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, I203M, L234I, R269K, D278A S283G 
GA11 GA11 None    S17N, D25E, V31I, M50I, L63I, I72IV, L74I, F100Y, L101I, T112V, T124TA, T125Q, K136Q, V201I, T218L, L234I, A265V, R269K, D278A S283DG 
GA12 GA12 None    E11D, D25E, V31I, K34R, M50MI, F100Y, L101I, T112V, T125A, V150A, V201I, T206S, K211R, I217V, L234I, A265AV, I268IL, R269RK, D278A S283G, R284G 
GA15 GA15 None   T97TA S17N, D25E, V31I, L45I, I72V, L101I, T112V, T124A, T125A, K136Q, G163Q, D167E, V201I, K211Q, T218I, L234I, D278A S283G 
GA18 GA18 None    S17N, V31I, I72V, I84M, L101I, T112V, T124A, K136Q, V201I, L234I, I251L S283G 
GA19 GA19 None    E10D, D25E, V31I, L45Q, M50L, I72V, F100FY, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, D278A S283G 
GA21 GA21 None    D6E, E11D, E13D, K14R, A21T, M22L, V31I, V37I, I72IV, I84M, P90PS, L101I, T112I, T124A, K136Q, V201I, L234I, D256E, D278A S283G, R284G 
GA23 GA23 None    D25E, V31VI, I72V, I84IM, L101I, T124A, T125A, I135L, K136Q, D167DE, K188R, V201I, K215N, T218N, L234I, A265AV, I268IL, D270DN, D278A S283G 
GA24 GA24 None    D6E, E11D, S17N, D25E, V31I, I72V, F100Y, L101I, T112V, S119P, T124A, T125A, K136Q, D167E, V201I, T218I, L234I, A265AV, R269K, D278A S283G 
GA25 GA25 None    K14R, D25E, N27H, V31I, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, T206S, L234I S283G 
GA26 GA26 None    D25E, V31I, I72V, L74LV, L101I, T112TAIV, I113IV, T124A, T125A, K136Q, V201I, T218I, L234I, K273Q, D278A S283G, R284RG, D288N 
GA27 GA27 None    E11D, E13ED, S24DG, D25E, V31VI, L45Q, I72V, A91T, L101I, T112I, T124A, K136Q, D167E, V201I, L234I, A265AV, D278A S283G 
GA29 GA29 None    S17SN, A21S, D25E, S39C, M50MI, F100Y, L101I, T112V, T124A, T125A, K188KR, V201I, T218L, K219N, N222K, L234I, S255ST, A265AV, I268IL, R269RK, D278DA  
GA32 GA32 None    S17N, D25E, V31VI, I84M, F100Y, L101I, T112V, T124A, T125A, K136Q, V165I, F181FL, K188R, V201I, T218L, K219N, N222K, L234I, A265V, D278A S283G 
GA33 GA33 None    R20RK, D25E, V31I, M50MT, I60V, F100Y, L101I, R107RK, T112V, T124NS, T125A, K136Q, V201I, T218L, K219Q, L234I, D270DE, D278A S283D, D286N 
GA36 GA36 None    D25E, L45Q, M50I, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, D270E, D278A S283G 
GA37 GA37 None    S17N, V31I, M50I, I72V, L101I, T112V, I113V, T124A, T125A, K136Q, V201I, T218I, L234I, A265V, R269K, D278A V281M, S283G 
GA40 GA40 None    S24N, D25E, V31I, M50I, I84M, A91T, F100Y, L101I, T112V, T124N, T125A, K136Q, V201I, K211R, T218I, L234I, A265V, D278A S283G 
GA44 GA44 None    S17N, D25E, V31I, M50T, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, V165VI, V201I, K215KQ, T218I, L234I, D256E, D278A S283G 
GA45 GA45 None    K14R, S17N, S24N, D25E, V31I, M50I, I72V, I84M, F100Y, L101I, T112I, T124A, T125A, K136Q, M154I, V201I, T206S, N222R, L234I V32VA, S283G 
GA46 GA46 None    E11D, S17C, D25E, V31I, M50L, I72V, I84M, F100Y, L101I, T112V, T124S, T125A, K136Q, V201I, L234V, A265V, D278A S283G 
GA50 GA50 None    D25E, V31I, I72V, L74I, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, K215N, T218I, L234I, A265V, R269K, D278A S283G, D288N 
GA52 GA52 None    K14KR, V31I, M50MI, I60IV, I84M, F100Y, L101I, K111KR, T112V, T124N, T125A, K136KQ, D167DE, F181FL, G193GE, V201I, I208L, K219N, N222K, L234V, V249VL, A265V, R269K, D278A D286N 
GA53 GA53 None    D25E, K34R, M50I, I84M, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, A265V, D278A S283G 
GA54 GA54 None    E11D, S24N, D25E, V31I, L45LQ, M50L, L101I, T112V, T124N, T125A, K136HQ, V201I, L234I, R269K, D278A I182IMV, S283G 
GA56 GA56 None    K14R, D25E, V31I, M50I, I72V, P90S, E96D, L101I, S119R, T124A, T125A, K136Q, Q177L, V201I, T218I, L234I, A265V, D278A S283G 
GA57 GA57 None    K14R, V31I, L74I, G106A, T112V, S119P, T125A, K136Q, D167E, V201I, T206S, D207E, L234I, S255N, D256E, C280Y S283G 
GA58 GA58 None    S17N, D25E, V31I, I72V, L101I, T112V, T124A, Q177L, K188R, V201I, Y227F, L234I, D256E, K264R, R269K, D278A S283G 
GA59 GA59 None    E11D, S17N, D25E, M50I, L74I, I84M, E96D, L101I, T112V, T124A, T125A, K136Q, V201I, T218TI, N222NT, R224RQ, L234I, D270DN S283G, D286N 
GA60 GA60 None    D6E, E10ED, E11EA, E13ED, D25E, V31I, L74I, I84M, Q95QH, T112V, T124A, T125A, K136Q, V201I, Q216H, K219KQ, L234I, D278A S283G 
GB05 GB05 None    K7R, E11D, D25E, V31I, L45Q, M50IV, I72V, L101I, T112V, S119P, T124A, K136Q, V201I, I220L, Y227F, L234I, R269K, D278A S283G 
GB09 GB09 None    D25E, L101I, T112V, T124N, T125AV, K136Q, V201I, T218I, K219Q, L234I, S255G, D278A S283G 
GB12 GB12 None    E11D, S24N, D25E, V31I, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, A265V, R269K, D278A H16HL, S283G 
GB15 GB15 None    V31I, M50I, I72V, I84M, L101I, T112TA, T124N, T125A, K136Q, D167E, F181FL, S195T, V201I, T206S, D207E, Y227F, L234I, A265V, R269K, D278A  
GB44 GB44 None    E11D, R20K, S24N, D25E, V31I, M50MI, I84M, Q95H, L101V, T112V, T125A, K136Q, E157Q, K160Q, V201I, N222H, L234I, D278A S283G, R284G 
GB65 GB65 None    V31I, M50T, L63I, I72V, L74I, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, T218I, L234I S283G, R284G, D288N 
GC19 GC19 None   G163KR D6DE, E10D, V31I, I72V, I84IM, E96D, L101I, K111Q, T112IV, T124A, T125A, K136Q, K156N, V201I, L234I, D278A S283G 
GC42 GC42 None    S17N, D25E, V31I, F100Y, L101I, G106A, T112V, T124A, T125A, K136Q, D167E, V201I, I203M, T218I, L234I S283G 
GC60 GC60 None    K14R, D25E, V31I, M50I, I72V, F100Y, L101I, T112V, S119P, T124N, T125A, K136Q, V201I, T206S, K215N, T218I, L234I, A265V, R269K, D278A S283G, D288N 
GD01 GD01 None    K14R, V31I, I60LM, I72V, L74V, T112V, I113V, T124A, T125A, V126F, I135IV, K136Q, D167E, V201I, L234I  
GD10 GD10 None    D25E, V31I, I72V, I84M, T112V, S119T, K136Q, V201I, T206S, L234I, I251L, A265V, D278A S283G 
GD104 GD104 None    D25E, M50I, I72V, A91T, F100Y, L101I, T112V, T124N, T125A, K136Q, V201I, I220V, L234I S283G, R284G, D288N 
GD16 GD16 None    D25E, V31I, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, L234I S283G 
GD22 GD22 None    E11D, K14R, A21T, D25E, V31I, M50I, I72V, L101I, K111R, T112I, T124A, T125A, K136Q, D167E, V201I, K211R, T218I, L234I, N254ND, V260I, R269K, D278A S283G 
GD30 GD30 None   L74LIM K14KR, D25E, V31I, I72IV, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, D278A S283G 
GD32 GD32 None    D6E, E13D, K14R, D25E, V31I, I72V, L101I, T112I, T124G, T125A, K136Q, V201I, T218L, L234I, A265V, R269K, D278A S283G 
GD58 GD58 None    V31I, M50I, L74I, F100Y, L101I, T112V, T125A, K136Q, G163E, K188R, V201I, K215N, T218I, L234I, A265V, R269K, D278A S283G, D288N 
GD80 GD80 None    D25E, V31I, F100Y, L101I, T112V, T125A, K136Q, H171Q, V201I, T218I, L234I, A265V, R269K, D278A V281M, S283G