<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Monleau (2012)
Title Drug resistance mutations of HIV type 1 non-B viruses to integrase inhibitors in treatment-naive patients from sub-saharan countries and discordant interpretations.
Citation ARHR
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 97
NumPts 97
Subtype CRF02_AG, C, H, F, J, D, G, CRF01_AE, A, K


Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
102-1024 102-1024 None    D6E, E13D, K14KR, V31VI, E87ED, Y99YF, L101I, T112V, T124S, D167E, K173R, K188KR, V201I, T206S, L234I, A265V, R269K, D278A L45L*Q, A276AE 
102-1029 102-1029 None    E11D, K14R, S24N, D25E, V31M, V32I, S39T, L45Q, M50T, I72V, F100Y, L101I, T112V, T124S, T125A, K136Q, V201I, T206S, T218I, L234I, R269K, D278A  
102-1030 102-1030 None    K14KR, V31I, I84M, A91AT, L101I, T112V, T124N, K136Q, K173R, V201I, L234I, R269K  
102-1033 102-1033 None    V31I, M50T, I72V, I84M, P90Q, F100Y, L101I, T112V, T124N, T125A, K136Q, V201I, L234I, R269K, D278A R284G 
102-1034 102-1034 None    D25E, V31I, T93N, L101I, T112V, S119P, T124N, K136Q, D167E, K173R, V201I, T218I, L234I, A265AV, R269K, D278A R284RG 
102-1046 102-1046 None    S17N, R20K, V31I, M50MI, L101I, G106A, T112V, T124N, K136Q, K173R, R187RK, V201I, K215N, T218I, R224Q, L234I, D270N, D278A S283N 
102-1061 102-1061 None    D25E, V31I, I84M, F100Y, L101I, T112V, S119P, T124S, T125A, I135IV, K136Q, K188KR, V201I, L234I, A265AV, R269K, D278A S283G 
102-1063 102-1063 None    S24SN, D25E, I72V, I84M, T112V, T124N, K136H, K173R, K188KR, V201I, T218I, L234I, A265V, R269K, D278A S283N 
102-1065 102-1065 None    E13D, D25E, M50I, F100Y, L101I, T112V, T124N, T125A, K136Q, V201I, K211R, T218I, I220V, L234I, D256E, A265V D288N 
102-1072 102-1072 None    D25E, V31I, M50I, I72V, I84M, L101V, T112V, S119P, T124N, K136Q, V201I, T206S, T218Q, K219Q, L234I, D278A  
102-1074 102-1074 None    E13D, V31I, M50MI, C56S, I84M, P90PS, L101I, T112V, S119R, T124S, T125Q, K136Q, V201I, I203IM, K211R, T218I, L234I, A265V, R269K, D278A  
102-1082 102-1082 None    K14KR, S17N, V31I, L101I, T112V, T124N, K136Q, K173R, T206TS, I208L, T218I, L234I, D256E, A265V, R269K, D278A  
102-1096 102-1096 None    S17N, D25E, I84IM, F100Y, L101I, T112V, T124N, T125A, K136Q, V201I, T218I, L234I, A265V, D279G  
102-1113 102-1113 None   L74M E10Q, E11D, E13D, V31I, M50I, I72V, L101I, T112V, I113V, T124N, F181L, K188R, G193E, V201I, T218I, L234I, A265V, R269K, D278A  
102-1118 102-1118 None    E10D, D25E, V31I, F100Y, L101I, T112V, T124S, T125A, K136Q, K156KN, E157Q, K160KQ, K173R, K188R, A196P, V201I, T218I, L234I, R269K, D278A E287D 
102-1120 102-1120 None    E13D, V31I, M50T, I84M, L101I, T112V, I113L, T124N, T125A, K136Q, H171Q, V201I, T218I, L234I, A265V, R269K, D278A  
102-1133 102-1133 None    D6E, E10D, D25E, M50I, I72V, L101I, T112I, T124S, K136Q, V201I, Q216R, T218I, K219Q, L234I, A265V, R269K, D278A  
102-1152 102-1152 None    E13D, V31VI, L45LI, M50MI, I84M, L101I, T112V, T124N, K136Q, V201I, T218I, L234I, A265V, D278A  
ABO ABO ABO ABO None    K14R, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, M154I, E157K, V201I, I203M, T206S, T218I, L234I, A265V S283G 
BUI BUI BUI BUI None    K7R, E11D, R20K, S24N, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, N222K, L234T  
CHA CHA CHA CHA None    K14R, A21T, V31I, S39N, L101I, T112V, T124A, T125A, I135V, K136Q, V165I, D167E, V201I, L234I  
CIR CIR CIR CIR None   T97A A23V, L28I, I72V, T112V, T124A, T125A, V126L, I135V, K160R, G163T, Q177H, F181L, V201I, T218I, L234I, A265V, D278A, C280V  
CIS CIS CIS CIS None    K14R, R20K, V31I, Q95P, L101V, G106A, K111T, T112V, S119T, T124A, T125A, G134N, I135V, K136T, V201I, T206S, K211R, T218I, L234I  
DES DES DES DES None   G163K E11D, V37I, C56S, I72V, I84L, L101I, T112I, I113V, S119P, T122S, T124A, T125A, K136Q, V201I, K211R, T218I, L234V, D256E S283G 
DON DON DON DON None   R263K K14R, V31I, M50T, P90S, Q95S, L101I, T112V, T124A, T125A, G134N, I135V, K136T, E157Q, V201I, T206S, L234I, E246D, S255G, A265S, Y271D  
DRA DRA DRA DRA None   T97A K14R, V31I, V32I, S39M, M50I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, Q137H, M154I, F181L, V201I, T206S, L234I  
DRC-365 DRC-365 None    S17N, A23AV, K34KR, L45LQ, M50I, Q53QH, L63LM, L74I, T112V, T124N, T125A, I135IV, V165I, V201VI, K211N, I220V, D232E, L234I, D256E, D270DE, D278N S283G 
DRC-375 DRC-375 None    K14R, V31I, I60V, I72V, L74I, L101I, K111Q, T112V, T124A, T125A, G134N, K136N, Y194C, V201I, E212L, T218L, K219N, N222K, L234I, D256E, A265T, I268L D288N 
DRC-446 DRC-446 None    K14R, K34KR, M50I, F100Y, L101I, T112V, T124A, T125A, K136Q, G163V, G193E, V201I, L234I, D278A S283G, D286N 
DRC-469 DRC-469 None   T97A K7R, S17N, G70GE, L101I, T112IV, T124G, T125A, K136Q, V165I, V201I, A205S, L234V, D256E S283G 
DRC-491 DRC-491 None    K14R, A23V, L28I, P30A, M50I, I60M, I72IV, V79I, Y99L, L101I, T112V, T125V, I135V, V201I, K211R, Y227F, L234I, D256E S283G 
DRC-514 DRC-514 None    K14R, A21T, A23V, V31I, M50I, I72V, L101I, T112V, I113IV, T124A, T125A, G134D, K136Q, D167E, V201I, T218L, K219N, N222K, L234I S283G, D286N 
DRC-526 DRC-526 None    K14R, S17N, S24N, V31I, I72V, L101I, T112V, S119P, T122TI, T124A, T125A, G134D, I135IV, K136Q, V201I, E212I, T218L, K219N, N222K, L234I, D256E S283G 
DRC-528 DRC-528 None    E11Q, S17SN, V31I, L101I, G106A, T112V, G134D, K136Q, V165I, V201I, T206S, I208IL, K219N, N222K, L234I, D256E S283G, R284G, D286N 
DRC-529 DRC-529 None    K14R, I60IM, Y99F, L101I, T112V, S119T, T124A, T125A, G134GDE, I135V, D167E, K173R, V201I, T206S, I208L, K211KR, E212V, T218I, L234I, D256E S283SG 
DRC-537 DRC-537 None    S17N, R20K, S39N, M50I, I72V, L101I, T112V, T125A, V126A, G134D, V201I, T218L, K219N, N222K, L234I, D256E T124DN 
DRC-551 DRC-551 None    K7R, S17N, S24N, K34R, M50T, I72V, T112V, T124A, T125A, K136Q, V165I, K173R, A205S, T218L, Q221H, N222K, L234I, D256E  
DRC-561 DRC-561 None    E11D, K14R, S17T, V31I, V37I, S39N, M50V, I72V, L101I, T112M, S119P, T124N, T125A, G134D, I135V, K136Q, V201I, E212A, T218L, K219N, N222K, L234I, D256E S283G 
DRC-577 DRC-577 None    K14R, D25DE, V31I, I60M, I84M, Y99F, L101I, T112V, I113IV, T124A, T125A, D167E, G193D, S195C, V201I, I203M, T206S, L234I, D256E, I268L, D270H S283G 
DRC-580 DRC-580 None    E11D, K14R, V31I, H51HQ, I60M, V79I, L101I, G106A, T112I, S119P, T124A, T125A, K127R, G134D, I135V, D167E, V201I, I203M, T206S, I208M, E212A, L234I, A265V S283G 
DRC-610 DRC-610 None    K7R, S17N, R20K, V31I, M50T, I72V, L101I, T112V, K136Q, V165I, K173R, V201I, I203IM, A205S, K219N, N222K, L234I, I251L, D256E  
DRC-639 DRC-639 None    K14R, S17N, V31I, K34R, S39N, I72V, G106S, T112V, T124A, T125A, I135V, K136Q, V165I, K173R, T218L, N222K, L234I, D256E, D270E  
DRC-641 DRC-641 None    K14R, S17N, S24T, V31I, S39N, I72V, L101I, T112V, T124S, T125V, G134D, I135V, K136Q, V165I, K173R, V201I, T218L, K219N, N222K, L234I, D256E  
DRC-810 DRC-810 None    E11D, A23AV, V37I, I72V, K111R, T112L, T124N, T125A, K136Q, V201I, T206S, L234V, D256E Q9QL, S283G 
DRC-825 DRC-825 None    E11Q, S17N, V31I, I72V, I84M, L101I, T112V, T124G, T125A, G134D, K136Q, V165I, V201I, T218S, K219N, N222K, L234V, D256E S283G 
DRC-909 DRC-909 None   L74M S17N, L28I, S39C, L101I, T112V, I113V, S119P, T124A, T125A, K136Q, V165I, D167E, V201I, T218S, Q221T, L234I S283G, D288N 
DRC-975 DRC-975 None    S17N, V31I, M50MI, I72V, G106S, T112V, T124A, G134D, K136R, D167E, K173R, V201I, T218L, K219N, N222K, L234I, D256E S283G 
DRC-KP1 DRC-KP1 None   T125K K14R, S17N, V32I, M50L, I72V, L101I, T112V, K136Q, K173R, K188R, V201I, A205S, Q221T, N222K, L234I, D256E, A265V S283G 
DRC-KSS0 DRC-KSS0 None    S17N, V31I, I72V, F100Y, L101I, T112V, T124N, T125A, K136Q, V201I, T206S, T218I, L234I, A265V, R269K, D278A V281M 
DRC-KTB DRC-KTB None    K14R, S17N, V31I, I60M, I72V, V79I, Y99FL, L101I, T112V, T124G, T125A, G134D, I135IV, V165VI, D167E, V201I, T218L, K219N, N222K, L234I, D256E S283G 
DRC-LBDS DRC-LBDS None    D25E, V31I, S39T, I72V, L101I, T112V, T124N, K136Q, V201I, T218L, K219N, N222K, L234I, A265V, R269K, D278A S283G 
DRC-LBFE DRC-LBFE None    E11D, K14R, V31I, L101I, K111Q, T112V, T124A, T125A, K136Q, S195T, V201I, L234I, R269K, D278A S283G 
DRC-LBS0 DRC-LBS0 None    S17N, V31I, M50T, I84M, L101I, T112V, T124S, T125A, K136Q, V201I, T206S, K215N, L234I, N254Q, I268L, D270H, D278A S283G 
DRC-MBT DRC-MBT None   L74M, T97A K14R, R20K, I72V, K111T, T112V, I113V, T124G, T125A, V165I, V201I, T218I, L234I, D256E S283G, D288N 
DRC-MBTB DRC-MBTB None   T97A D25E, V31I, M50I, L101I, T112V, I113V, T124A, T125A, K136Q, V201I, T218I, L234I, A265V, R269K, D278A S283G 
DRCL-BS0 DRCL-BS0 None    D25E, V31I, M50I, L74I, L101I, T112IV, T124A, T125A, K136Q, D167E, K188KR, V201I, Q216R, T218I, K219Q, L234I, A265AV, R269K, D278A S283G 
DRCL-BTB DRCL-BTB None    S17N, V31I, I72V, I84M, E96D, L101I, K111Q, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, A265V, D278A S283G 
ELV ELV ELV ELV None    K14R, V32I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I  
ETI ETI ETI ETI None    K14R, S57G, L74I, E96D, L101I, T112I, T124G, T125A, G134N, I135V, V201I, T206S, Q221T, L234I  
LEF LEF LEF LEF None    E11D, S24T, V31I, I72V, L101V, T112V, S119P, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I  
LOA LOA LOA LOA None   T97A K14R, V31I, E96D, A98S, L101I, T112V, T124A, T125A, K136T, D167E, V201I, T206S, K219N, N222K, L234I, K240N, E246D, I268L, D270H S283G 
MAU MAU MAU MAU None   T97A, G140E E13K, K14R, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, M154I, V201I, T206S, L234I E152K 
NSI NSI NSI NSI None    K14R, S24N, V31I, I72V, L101I, T112V, T124A, T125A, G134S, I135V, K136T, V201I, T206S, L234I  
SAR SAR SAR SAR None    V31I, L101I, T112V, S119T, T125A, G134N, I135V, K136T, V201I, I203M, T206S, T218I, K219Q, L234F, K240N  
SK1002 SK1002 None    S24G, I72V, T112V, I113V, T124A, T125A, K188KR, V201I, T206S, K211KR, L234I, A265AV, I268IL, D270H S283G 
SK1004 SK1004 None    E11D, E13ED, K14KR, S17ST, S24SN, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269RK G47GR, S283G 
SK1006 SK1006 None    E11D, S17C, V31I, I72T, I84M, L101I, K111KR, T112K, T124A, T125A, G134N, I135V, K136T, D167E, V201I, T206S, T218I, L234I, A265AV, R269K S283G 
SK1009 SK1009 None    K14R, S17N, V31I, M50MI, L101I, T112I, T124A, T125A, G134N, K136T, I141IV, K156R, V201I, T206S, Y227F, L234I, S255N, D256E S283G 
SK1013 SK1013 None    K14R, S57SG, I72IV, A91AS, Q95QH, G106GA, T112V, T124A, T125A, V126VIM, G134N, I135V, K136T, I141V, V201I, T206S, L234I S283G 
SK1017 SK1017 None    E11D, S24G, D25E, S39C, L45V, M50V, L101I, T112I, T125V, K136Q, V165VI, V201I, Y227F, L234V, D256E  
SK1018 SK1018 None    K14R, V31I, S39C, I72V, K111KR, T112V, T124A, T125A, G134N, I135V, K136T, S195ST, V201I, T206S, L234I, I251IL, S255T, A265AITV, R269RK, D270DN S283G 
SK1023 SK1023 None    K14R, V31I, L74I, L101I, T112V, T124A, T125A, G134D, I135V, K136T, K188KR, V201I, T206S, T218TI, L234I, A265V, R269RK, D279G  
SK1025 SK1025 None    K14R, V31I, L45LI, I72IV, T112V, I113V, T124A, T125A, K156N, E157Q, D167E, V201I, K211R, R224RW, L234I, A265V Q221Q*, L241LF, S283G 
SK1033 SK1033 None    E11ED, K14R, V31I, L101I, T124A, T125A, G134D, K136T, R187RK, V201I, T206S, T218TS, Y227F, L234I, S255N, D256E G193GEKR, S283DG 
SK2003 SK2003 None    E11D, K14R, A21T, V31VI, K34KR, L45LQ, T93TI, L101I, T112IV, T125A, G134N, K136T, V165VI, D167DE, V201I, T206S, I208IM, K219N, N222K, L234I, D270H S283G, R284G 
SK2032 SK2032 None    E11D, A21T, A23V, V31I, D41N, M50I, L101I, T112V, T124A, T125V, G134D, K136Q, D167E, K173R, V176VL, V201I, L234I I72IMV, S283G 
SK3002 SK3002 None    K14R, S24H, V31VI, S39C, L101IV, T112V, T124N, T125A, G134N, G163E, D167E, V201I, T206S, I208L, K211KR, Q216H, I220IL, Q221S, L234I  
SK3015 SK3015 None    K14R, R20K, L74I, L101I, T112TI, T124A, T125A, G134D, K136Q, V201I, I208IL, K211KRT, R224RW, L234I, S255N, D256E, D279G S283G 
SK3035 SK3035 None    E11D, E13ED, K14R, S24N, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, F181FL, G193GR, V201I, T206S, K211KR, T218I, L234I, N254K, A265V K266KQ, S283G 
SK3036 SK3036 None    E13ED, K14R, S24HN, V31I, A91AS, E96D, L101I, K103R, T112V, S119R, T124A, T125A, G134N, K136T, V165VI, V201I, T206S, I208L, T218TS, Y227F, S230N, L234I, S255N, D256E S283G 
SK3052 SK3052 None   T97TA K14KR, V31VI, K34KR, I72IV, T93TI, L101LI, T112IV, T124A, T125A, G134GD, K136Q, D167E, V201VI, I208L, Q216HN, N222NK, D232DN, L234I, M275MV Q221Q*, S283G 
SK4022 SK4022 None    K14R, V31I, L101I, K111KQ, T112TAIV, S119ST, T124A, T125A, G134N, I135V, K136T, V201I, T206S, K211KR, R224RW, L234I, R269K Q221Q*, D286A 
SK4047 SK4047 None    E11D, K14R, S24N, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, E157EQ, K160KQ, V201I, T206S, T218TI, L234I, R269K V281VM, S283G, D286E 
SK4053 SK4053 None    E11ED, K14R, D25E, V31VI, K34KR, D41DN, L101I, T112I, S119P, T124A, T125A, G134DN, K136T, D167E, V201I, T206S, D207DE, I208L, T210TI, E212EG, L234I K211KEGR, S283G, D288N 
SK4064 SK4064 None    D6S, K7E, E10D, E13D, I72V, L101I, T112V, I113V, T124G, T125P, E157EQ, K160X, V201I, Y227F, L234I, D253H, D256E, D279G R284G 
SK4069 SK4069 None    E11ED, K14KR, R20RK, V31I, I72V, L74IV, K103KR, T112V, I113IV, T124A, T125A, G134D, K136Q, D167E, V201I, L234I S283G 
SK4071 SK4071 None    K14R, A21AT, V31I, I72IV, L101I, T112IV, I113V, T124A, T125A, G134N, K136Q, D167DE, V201I, I208L, K211KR, L234I, A265AV S283G 
SK4072 SK4072 None    D6E, E11D, E13ED, K14KR, S17SN, S24SN, V31I, T93N, L101I, T112V, T124A, G134N, I135IV, K136T, V201I, T206S, L234I, D256E, R269K S283G 
SK4073 SK4073 None   T97A K14R, S24N, I72IV, L101I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, T218S, L234I, S255N, D256DE S283G 
SK4079 SK4079 None    K14R, V31I, L101I, K111Q, T112V, I113IL, S119P, T122I, T124A, T125A, D167E, V201I, T206S, L234I, I251IL, D256E, A265V S283G 
SK5010 SK5010 None    E11D, K14R, A21T, A23V, V31I, M50I, I72V, L101I, T112V, T124A, G134N, K136Q, D167E, V201I, Q216H, Y227F, L234I, D256E, V260I S283G 
SK5013 SK5013 None    K14R, R20K, V31I, M50I, I72V, L101I, T112V, T124A, G134N, I135V, K136T, V201I, T206S, L234I, S255N, D256E, A265AV, I267IV, I268IV, R269RK S283G 
SK5026 SK5026 None    E11D, K14R, S24N, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I S283G 
SK6007 SK6007 None    D6DE, E11D, E13D, S24SN, V31I, I60M, I72V, T112V, T124A, T125A, V126M, G134N, I135V, V201I, T206S, L234I, A265V, R269RK K186R, S283G 
VEH VEH VEH VEH None    K14R, S57G, E96D, L101I, T112V, T124N, T125A, G134N, I135V, K136T, V201I, T206S, L234I, E246D, N254T  
VIA VIA VIA VIA None    K14R, V31I, I72V, L101I, T112V, T124A, G134N, I135V, K136T, V201I, T206S, L234I  
WIL WIL WIL WIL None    E11D, E13D, S17T, A23V, V31I, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I