<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Brenner (2011)
Title Subtype diversity associated with the development of HIV-1 resistance to integrase inhibitors.
Citation J Med Virol
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 157
NumPts 150
Subtype B, C, CRF01_AE, CRF02_AG, A, F, J, D, G


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Page 1   from Isolate 1 to Isolate 100 from Total 157 Clinical IN Isolates

SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
10022 10022 None    K14R, A21T, V31I, I72V, T112V, I113V, T124A, T125A, G134N, K136T, Y194D, V201I, L234I, N254K, S255G, A265V, R269K  
10077 10077 None    K14R, S24N, V31I, I84M, Y99F, L101V, T112V, T124N, T125A, K136Q, V201I, T206S, L234I, I251L, A265V, R269K, D278A  
10082 10082 None    K14R, A21T, V31I, S57G, L74I, A98G, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, D256E, I268L S283G 
10106 10106 None    E11D, S24N, D25E, M50I, K111T, I203M  
10141 10141 None    E11D, D25E, V31I, L45Q, M50MI, A91T, L101I, T112V, K136Q, V201I, T218I, L234I, D278A Q95Q*PS, S283G 
10205 10205 None    S24N, D25E, F100Y, L101I, T112V, T124NS, T125A, D167E, K188R, V201I, K215N, T218L, L234I, R269K, D278A S283G 
10207 10207 None    K14R, V31I, M50I, I84M, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, Y227F, L234I, N254S, S255G, D256E S283G 
10276 10276 None    R20K, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, G193D, S195C, V201I, K211Q, L234I, D278N  
10287 10287 None   V151I I72V, I113V, L234V  
10322 10322 None    K14R, S17N, V31I, I60M, I72V, T112V, T124A, T125A, G134N, K136Q, D167E, V201I, Y227F, N254D, S255K, A265V S283G 
108PHI 108PHI None    E11D, S17C, N27G, P30A, V32I, S39R, I72V, L101I, T122I, T125P, K136N, T206S, I208L  
111NB 111NB None    E11D, K14R, V32I, T124A, V201I, I208L, K211KQ, S230N, D256E  
117PHI 117PHI None    E11D, A21T, L45V, L101I, T112M, S119SG, T122TI, T124N, I182V, I220IV, L234FI  
118PHI 118PHI None    E11D, S17C, I72V, T112I, I113V, T124A, T206S, L234I  
120NB 120NB None    K14R, S24H, I72V, T112V, I113V, T124A, T125A, G134N, K136KT, V165I, V201I, T206S, L234I, D270N S283SG 
131NB 131NB None    E11D, K14R, V32I, T124A, V201I, I208L, K211KQ, S230N, D256E  
150NB 150NB None    E11D, V32VI, P90PT, S119SR, T122TI, T124A, V201I, I208L, K211Q, S230N, D256E  
179NB 179NB None    E11ED, K14R, T124A, V201I, I208L, K211Q, S230N, D256E, V259VI  
184NB 184NB None    S17SN, R20K, E96D, L101I, T112R, T124A, T125A, I135V, K136Q, V201I, A205S, D232E, L234V, D256E S283G 
185NB 185NB None    K14R, V31I, L101I, T112V, T124N, T125A, G134N, I135V, G163E, S195T, V201I, T206S, L234I S283G 
188NB 188NB None    S17N, I72V, L74LI, T112V, I113V, T124A, M154MI, V201I, K211R, L234I, A265V  
189NB 189NB None    E11ED, K14R, V32I, T124A, V201I, I208IL, S230N, D256E  
190NB 190NB None    S17N, R20RK, D25E, V31I, L101I, T112V, T124N, K136Q, K173R, V201I, T218L, L234I, I251IL, R269RK, D278A D207DV, S283G 
51PHI 51PHI None   L74M E11D, M50I, L101V, M154L, K211Q, D278N  
5326 5326 None    K7R, E11D, K14R, V31I, V32I, M50L, L101I, T124N, S195T, I203M, I220L, Y227F  
5799 5799 None   V151I I72V, I113V, L234V  
5969 5969 None    S17N, A23V, V31I, I72V, I113V, T124N, V201I, A265V  
5971 5971 None    E11D, V32I, S119P, T122I, K136N, S195T, V201I, T206S, V259I R284G, D286N 
5980 5980 None    E11D, E13D, K14R, S24N, D25E, V31I, S39ST, F100Y, L101I, T112V, T124S, T125A, K136Q, V201I, T206S, I208IM, T218TI, L234I, A265AV, R269K, D278A  
6058 6058 None    E11D, K14R, V201I, I208L, K211Q, S230N, D256E  
6240 6240 None    K14R, A21T, V31I, S39N, I72V, T112V, T125A, V126L, K127KR, G134N, I135V, K136R, D167DE, V201I, I203M, L234I S283G 
6297 6297 None   V151I D6T, E10D, V31I, M50T, I113IV, S119ST, T125A, K156N, D167E  
6305 6305 None    S17N, S39C, L45LQ, I72V, L101I, G163E, H171Q, V201I  
6352 6352 None    E11D, E13D, K14R, S24N, D25E, V31I, F100Y, L101I, T112V, T124S, T125A, K136Q, V201I, T206S, T218TI, L234I, A265V, R269K, D278A S283SG, R284RG 
6390 6390 None    E10D, K14R, V31I, Q53H, L63I, I72V, L101M, T112A, T124N, K136Q, E157EQ, I208M, T218S, L234I S283G 
6527 6527 None    E11D, E13D, V31I, V32I, L101I, S119P, T122I, K136N, S195T, V201I, V259I R284G, D286N 
6558 6558 None    E11D, S24N, D25E, G106A, I113V, V201I, D256E, Q274QK S283G, R284G 
6740 6740 None   Q95K E11D, R20K, D25E, V31I, V37I, M50MI, I60V, K71Q, A91E, F100Y, L101I, T112V, S119R, T125A, K136Q, E157Q, K160Q, V201I, T218I, L234I, I251L, A265V, R269K, D278A S283G 
6771 6771 None    D6E, E11D, S17N, R20K, V31I, M50I, S119P, T122I, T125A, K156N, K219N, N222K, S230N, D256E  
6799 6799 None    E11D, D25DE, V31I, I72V, T112A, T124N, T125I, M154L, D256E S283G 
67PH 67PH None    L28I, L45Q, I84M  
6811 6811 None    E11D, V31I, S119P, T122TI, S195T  
6816 6816 None    D6E, E11D, S17N, R20K, V31I, M50I, S119P, T122I, T125A, K156N, K219N, N222K, S230N, D256E  
6852 6852 None    E11D, V31I, I72V, T112A, T124N, T125I, M154L, V165H, D256E S283G 
6958 6958 None    E11D, D25DE, V31I, I72V, T112A, T124N, T125I, M154L, D256E S283G 
7029 7029 None    E11D, V31I, S119P, T122I, S195T, D256E  
7034 7034 None   Q148LP K14R, A23AG, V31I, G59GR, A80S, Q95P, T112V, T124N, T125A, K136Q, M154I, E157Q, K160Q, A169AG, G193GR, S195SR, V201I, L234I N144ND, S283G 
7093 7093 None    S17N, V31I, S119P, T122I, T124A, T125A, K156N, K219N, N222K, S230N, D253DH, D256E  
7121 7121 None    E11D, V31I, S39N, S119P, T122I, S195T, D256E  
7187 7187 None    D6E, E13D, S17N, K111T, I113V, T124N, T125A, D232E  
7234 7234 None    E11D, K14R, V32I, T124A, V201I, I208L, K211Q, S230N, D256E  
  7234_1 None    E11D, K14R, V32I, T124A, V201I, I208L, K211Q, S230N, D256E  
7273 7273 None    E10D, L28I, S39C, I72V, L101I, T122I, T124A, S230N, A265V  
7284 7284 None    E11D, V31I, S119P, T122I, S195T, D256E W61WR 
7295 7295 None    K14R, V31I, L101I, T112V, T124N, K136Q, V201I, K211Q, T218I, L234I, A265V, R269K, D278A S283SG 
7316 7316 None    K14R, A21T, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, I203M, L234I S283G 
7335 7335 None   Q95K E11D, R20K, D25E, V31I, V37I, M50MI, I60V, K71Q, A91E, F100Y, L101I, T112V, S119R, T125A, K136Q, E157Q, K160Q, V201I, T218I, L234I, I251L, A265V, R269K, D278A S283G 
7462 7462 None    E13D, K14R, V31I, M50I, L101I, T112IV, S119T, T124G, T125A, G134S, V201I, T206S, I220L, Q221S, L234I, A265AV S283G 
7607 7607 None   V151I D6T, E10D, V31I, M50T, I113V, T125A, K136T, K156N, D167E  
7642 7642 None    E11D, K14R, A21T, V31I, M50MV, I72V, T112V, I113V, T124A, T125A, G134N, K136Q, V201I, L234I, I268IL S283G 
7651 7651 None    E11D, V31I, L101I, K111T, S119P, T122I, T124A, T125S, V201I, I203M, I208M, D256E  
7671 7671 None    D6E, S17N, I72V, K111T, I113V, S119T, T124N, T125A, I135V, D232E, L242LF  
7750 7750 None    K14R, V31I, A80S, Q95P, T112V, T124N, T125A, K136Q, E157Q, K160Q, V201I, L234I S283G 
7808 7808 None    K14R, A21T, V31I, I72V, T112V, I113V, T124A, T125A, G134N, K136T, V201I, L234I, N254K, S255G, A265V  
7822 7822 None    S17N, R20K, V31I, L45I, M50I, S119P, T124A, T125TA, K156N, V201VI, T206S, K219N, N222K, S230N, D256E  
7912 7912 None    Y194C, V201I, T206S, K211R, I268L, D270H  
7913 7913 None   G163R E10D, V31I, M50I, Q53H, L63I, I72V, L101I, T218S, L234I  
7924 7924 None    S17N, A23V, V31I, I72V, K111KQ, I113V, T124N, T125A, V201I, A265V  
7980 7980 None    K14R, V31I, S39N, I72V, I84V, T112V, T125A, V126L, G134N, I135V, K136R, M154I, D167E, V201I, L234I S283G 
7992 7992 None    S17N, L28I, S39C, I72V, I73V, L101I, T122I, T124A  
8100 8100 None    S17N, A23V, V31I, I72V, I113V, T124N, V201I, A265V  
8173 8173 None    E10D, L101I, T124A, F185Y  
8214 8214 None    S17N, S39C, I72V, L101I, G163E, H171Q, V201I L45EV 
8259 8259 None    E13D, K14R, V31I, M50I, L101I, T112IV, T124G, T125A, G134S, V201I, T206S, I220L, Q221S, L234I, A265V S119IT, S283G 
8265 8265 None    S17N, L28I, S39C, I72V, L101I, T122I, T124A, Y227F  
8271 8271 None    D6E, S17N, S24G, I72V, K111T, I113V, T124N, T125A, I135V, D232E  
8384 8384 None    Y194C, V201I, T206S, K211R, I268L, D270H  
8446 8446 None    E11D, K14R, V201I, I208L, K211Q, S230N, S255SN, D256E  
8488 8488 None    K14R, V31I, A80S, Q95QP, T112V, T124N, T125A, K136Q, E157EQ, K160Q, V201I, T218TI, L234I S283G 
8497 8497 None    E10D, L28I, S39C, I72V, L101I, T124A, A265V  
8556 8556 None    E11D, K14R, S24N, G106A, I113V, V201I, T206S, D256E S283G, R284G 
8703 8703 None    E11D, I72V, I84V, S119P, T122I, K136N, S195T R284G, D286N 
8849 8849 None    K14R, A21T, V31I, I72V, T112IV, T124A, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N S283G 
8896 8896 None    E11D, E13D, K14R, S24N, D25E, V31I, S39T, F100Y, L101I, T112V, T124S, T125A, K136Q, V201I, T206S, L234I, R269K, D278A R284G 
8989 8989 None    E11D, E13D, S24N, D25E, V31I, M50L, L101I, G106A, T112V, S119T, T124TA, K136Q, V165I, D167E, V201I, T206S, L234I, S255N  
9022 9022 None    K14R, S24N, V31I, I72V, L74I, T112IV, I113V, T124A, T125A, G134D, K136Q, D167E, V201I, I208IM, E212EA, K219N, N222K, L234I S283G 
9073 9073 None    K14R, V31I, M50T, L101I, T112V, T124N, T125A, G134N, I135V, K136T, E157Q, V201I, T206S, T218I, L234I, R269K S283G 
9074 9074 None    E11D, K14R, A21T, A23AV, V31I, I72V, L101I, T112V, T124A, G134N, V201I, L234I, A265V, R269K  
9125 9125 None    E11D, E13D, S24N, D25E, V31I, M50L, L101I, G106A, T112V, S119T, T124A, K136Q, E157EK, V165I, D167E, V201I, T206TS, K211R, L234I, S255N  
9139 9139 None    E11D, S24N, D25E, V32VI, A38AT, L45LQ, F100Y, L101I, T112V, T125A, K136Q, V201I, T218L, L234I, R269K, D278A  
9146 9146 None    S17N, D25E, V31I, L45V, F100Y, L101I, T112V, T124A, T125A, K136Q, G163E, V201I, Q216R, T218I, K219Q, L234I, R269RK, D278A S283G 
91NB 91NB None    E11D, K14R, V32I, T124A, V201I, I208L, K211Q, S230N, D256E  
9281 9281 None    E11D, S24SN, V37I, G106A, T112TI, I113V, T124TN, T125A, V201I, T206S, D256E S283G, R284G 
9329 9329 None    S17N, D25E, V31I, S39SN, M50I, I72V, F100Y, L101I, T112V, T124A, T125A, K136HQ, M154I, E157Q, K160Q, K188KR, V201I, Q216QH, L234I, D253E, D256E, A265AITV, R269K, D278A S283G 
9389 9389 None    S17N, A23V, L45LI, I72V, I113V, T124N, V201I, N254NK, D256DE, A265V  
9550 9550 None    D6E, V37I, I72V, T112V, T124N, T125A, K136Q, E157K, V201I, D278A S283G, D288N 
9574 9574 None   Q95K E11D, R20K, D25E, V31I, V37I, M50MI, I60V, K71Q, A91E, F100Y, L101I, T112V, S119R, T125A, K136Q, E157Q, K160Q, V201I, T218I, L234I, I251L, A265V, R269K, D278A S283G 
9599 9599 None    E11D, S24N, D25E, M50I, K111T, I203M  
9604 9604 None    V31I, I72V, T112A, T124N, T125M, M154L, S230N, D256E S283G 
9611 9611 None    K14R, S24N, V31I, M50IT, I72V, L74I, T112V, I113V, T124A, T125A, G134D, K136Q, D167E, V201I, E212A, K219N, N222K, L234I S283G