<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Rolland (2011)
Title Genetic impact of vaccination on breakthrough HIV-1 sequences from the STEP trial
Citation Nat Med
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 67
NumPts 67
Subtype B, CRF02_AG

Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
0006 consensus_0006 None None   I135T, K166R, Q174H, F214L, K277R, Q278H, T286A, I293V, E297K, D324P, I329L, R358K, A360T, T377I, K390R, V435I, D460N, V466I, H483Y, Q520L, Q524E  
0053 consensus_0053 None None   V21I, T27S, V60I, K122Q, S162A, E169D, I202V, Q207K, R211A, A272P, K277R, I293V, Q334L, G335S, M357T, T377M, A400T, E404D, E432D, V435A, D460N, H483Y, S519N, K530R, A534T, I556V  
0062 consensus_0062 None None   D123E, D177E, G196E, V245E, A272G, V292I, I326V, K390R, K451R, R463K, S468P, K527Q, V559I  
0176 consensus_0176 None None  A98G V60I, R211Q, F214L, V245R, K277KR, A288S, I293V, Q334E, M357T, K366R, K390R, A400T, R463K, A554T  
0223 consensus_0223 None None D67N  T39A, A98S, D123E, D177E, I178M, T200A, E204K, Q207E, V245E, K281R, L283I, I293V, T338S, S379G, K390R, V435T, T470N, L491S, S519N, V531I, A554S  
0227 consensus_0227 None None   V35VIM, K103KR, D121Y, K122E, I135T, S162C, I178M, R211RG, A272P, K277R, T286A, Q334L, A376S, T377M, K390R, A400T, I434IV, L452S, D460N, R461K, Q464H, V467I, S519N  
0287 consensus_0287 None None  V179D V35I, D123E, I135T, Q207E, I293V, I329L, G335D, R356K, M357V, N447S, S468P, A554T  
0309 consensus_0309 None None   V60I, S68G, I135T, T165I, T200A, E204A, R211K, E248K, K277R, T286A, I293V, E297A, I326V, Q334L, R356K, A360T, T369A, V381I, K390R, A400T, T403M, E449D, V467I, H483Y, Q509K, K530R, A554S  
0322 consensus_0322 None None   V35M, T39A, R83K, K122P, D177E, G196E, F214L, A272P, K277R, T286A, E297R, A376T, K390R, A400T, D460N, S468T, Q509H, S519N, A554S  
0341 consensus_0341 None None   V35M, R83K, T165I, R211K, V317A, S322T, A376T, K390R, A400T, V435E, L452S, D460N, L469I, L491P  
0346 consensus_0346 None None   S162C, R211K, T286A, V292I, I293V, G333E, P345Q, K366R, A376S, T403M, V435A, L452S, S468P  
0364 consensus_0364 None None  Y181C V35T, T39L, K122E, D123E, I135T, T200A, Q207E, L228H, T286A, T296S, E297K, R307K, D324E, K366R, A376T, E399D, A400T, V435E, K454R, D460N, R461K, S468T, L491S, L503I, K512Q  
0388 consensus_0388 None None   V90I, K122E, I142V, S162Y, P170T, V179I, T200I, V245K, E248D, D250E, A272P, K277R, I293V, E297A, I329L, R358K, A376T, E399D, A400T, E432D, D460N, V467I, L491S, Q524E, A554S  
0491 consensus_0491 None None   K102Q, K103R, I135T, I178M, V179I, Q207E, R211K, V245T, D250G, A272P, K277R, A288S, P294S, E297K, Q334Y, M357V, G359S, A371T, T403M, L452I, V467I, S468P, H483Q, A554T, K558R  
0524 consensus_0524 None None   V60I, K104R, D123E, I135T, K173R, N175Y, G196E, T200E, Q207N, V245T, A272P, K277R, P294S, E297K, L310I, Q334Y, R358K, V365I, K390R, T403M, V435A, L452I, V467I, L517V, K527S  
0525 consensus_0525 None None   K20R, K102Q, K103R, D123E, D177E, G196K, Q197E, T200E, R211K, F214L, V245I, P294T, Q334L, T338S, R356K, V435L, R461K, R463K, L469I, H483Y, E516D, S519N, E529K, K530R  
0572 consensus_0572 None None   D177E, G196E, R211A, K277R, T286A, E297K, E312A, I326V, Q334L, T377L, L491S, L517V, Q524E, K527R, A534T, K558R  
0648 consensus_0648 None None  V179D V35I, V60I, R83K, K102R, K122E, I135T, T200I, L210S, I293V, P294T, H315Y, M357T, G359S, K390R, E399D, A400T, V435A, D460N, S468H, H483N, L491S, A554T, K558R  
0717 consensus_0717 None None   I135V, S162C, R211K, V245M, I293V, R356K, T362S, A400I  
0762 consensus_0762 None None   V35I, R83K, K102Q, K122E, E169D, R211K, E248D, T286A, E291D, V317A, A376T, E399D, A400I, D460N, K512T, S519N, Q524E  
0823 consensus_0823 None None  K103N K20R, T39A, I142V, S162C, G196E, T200I, R211G, V245E, A272P, V276I, E312A, I329L, G333E, R356K, M357S, E404D, V458I, R461K, V466T, T470M, L491V, K512R, V548I  
0839 consensus_0839 None None   D123E, S162C, D177E, R211K, V245VM, E248ED, D250DE, A272P, K277R, T286A, I293V, I329L, G333E, F346Y, M357MI, R358RK, T377M, K390R, A400T, E430EK, V435I, L452S, S519N  
0841 consensus_0841 None None   E6K, F87L, K103R, K122E, K173E, L283I, V292I, I293V, K311R, Q334L, F346Y, M357T, K374R, A376T, T377Q, K390R, E399D, A400T, R463K, T470I, Q480K, H483Y, L491S, S519N, K527G, K530R  
0879 consensus_0879 None None   V60I, S68G, I135T, T165I, I178IM, T200A, E204A, R211K, E248K, K277R, T286A, I293V, E297A, I326V, Q334L, R356K, A360T, T369A, V381I, K390R, A400T, T403M, N447NS, E449D, V467I, H483Y, Q509K, K530R, A554S  
0897 consensus_0897 None None   V60I, D123E, D177E, I178M, Q207E, R211K, K277R, I293V, P294S, I329V, Q334H, T369A, A400T, E404D, F416Y, E432D, D460N, L469I, D471N, H483Y, L491S, S519N, A554K  
0923 consensus_0923 None None   R83K, V90I, D123E, K166R, D177E, I178V, I202V, R211K, A272P, K277R, T286A, Q334E, P345T, E404D, V435M, D460N, R461K, V467I, S519N, Q547K, A554T  
0938 consensus_0938 None None   S162C, G196E, A272P, K277R, T286A, I293V, E297T, Q334L, R358K, L452I, S468P, T470N, H483Y, K527N  
0961 consensus_0961 None None M41L, T215E G190A K101A, D123E, S162C, D177E, Q207E, R211K, A272P, K277R, I293V, D324E, Q334L, K350R, A360T, I382T, K390R, A400L, V435A, L452I, R461K, L469I, Q524E  
0965 consensus_0965 None None   I5V, V10X, G18X, E53X, I63X, K65E, P95X, P119X, K122X, K126X, L149X, Q161X, E169X, K173X, D177E, I178X, T200A, R211X, L228X, L234X, D250E, V261X, L264I, A272P, V276X, T286A, L303X, Y318X, L325X, I329X, G335S, M357X, A376X, T377X, I382X, E396X, A400T, T409X, E430X, L452X, V467I, H483X, L491S, I495V, L517V L12I, Q330d, K331d, G333K, E378R, A408P 
1027 consensus_1027 None None   R83K, D123E, N175H, D177E, K201I, A272P, T286A, P345T, V365I, K390R, K431Q, V435I, A554S, K558R  
1046 consensus_1046 None None   E36D, I142V, E169D, R211K, V245M, A272P, K277R, T286A, E297K, D324E, M357T, K366R, A376N, S379C, V435A, S468P, H483Y, K527N, K530R, A554T, K558R  
1047 consensus_1047 None None   D123E, D177E, V179S, G196E, Q207E, R211K, K277R, T286A, E297K, K311R, P321S, I329V, Q334C, T369V, K385R, K390R, E399D, T403M, V435I, L469M, L517I, A554N, V559I  
1055 consensus_1055 None None   K20R, K49R, K102Q, K122E, I135T, S162C, I178M, V245E, K275R, I293V, Q334Y, M357T, A360T, I375V, T386I, K390R, E396D, D460N, L517I, S519N, A554T, I556V, K558R  
1115 consensus_1115 None None   A272P, K277R, T286A, I293V, E297A, R358K, A376T, K390R, T403I, A437V, S468P, H483Y, L491S, Q520L, A554T  
1174 consensus_1174 None None   R83RK, K122E, D123DN, I135IT, S162C, E169ED, K173KE, D177DE, I195IM, G196GE, T200TA, Q207QKPT, R211RK, F214FL, A272P, E297K, I326IV, G333GE, Q334QE, M357T, T377TR, V381VI, K390KR, A400AT, V435VAIT, D460DN, R461RK, S468SP, L491S, L517I, S519N, Q524E, A554S  
1191 consensus_1191 None None   K102Q, D121Y, K122E, I135A, S162Y, Q197E, R211K, A272P, V276VI, K277KR, I293V, E297T, K311R, S322T, I329L, A400I, R461K, V467I, S468N, A554N, K558R, V559I  
1211 consensus_1211 None None   K122E, A158S, S162A, D177E, I178M, R211S, V245E, A272P, K277R, I293V, A360T, K366R, T377M, K431R, S468P, L469I, Q524E  
1368 consensus_1368 None None   K122E, V189I, Q197E, F214L, V245M, E248D, S322T, D324E, F346Y, M357T, A376T, T377Q, A400I, V435E, D460N, V467I  
1399 consensus_1399 None None   E28A, Q207GR, R211K, V245M, A272P, T286P, E297A, V317A, I329L, T338S, E344D, M357T, V365I, T369V, A376T, K390R, T397M, A400S, T403A, K431T, L452LI, D460N, R461K, H483Y, L491S, E516D, S519N, A534T, I556V, K558R  
1400 consensus_1400 None None   K64R, K104R, I135T, I178M, Q207H, R211K, I257L, A272P, V317A, M357V, A376T, T386V, A400I, V435E, A437V, D460N, L491S, K512T, S519N, K527T, A554S  
1478 consensus_1478 None None   V35T, E40D, T165I, G196E, Q197K, K277R, D324E, I329V, G333E, Q334N, T369A, A376T, K390R, A400T, K431R, V435A, S468P, H483N, A554S, K558R  
1500 consensus_1500 None None   I135T, R211K, F214L, A272T, K277R, Q278H, T286A, A288S, E297R, L303M, L310I, V317A, Q334E, A376T, T386I, A400T, T403A, P421L, E432D, V435A, F440Y, K454R, G490A, L491S, A508G, Q509H, V548I, A554T  
1504 consensus_1504 None None   D123E, I135T, I142V, K166R, D177E, I178V, G196E, T200A, R211K, V245E, E248N, A272P, T286A, E297K, S322SA, L325I, I341L, M357T, K390R, A400S, V417VI, V435VL, L452S, D460N, R461K, L491P, I506L, S519N, K527Q, A534S  
1512 consensus_1512 None None  V179D K20R, E40D, K122P, D123E, S162C, D177E, I195L, Q207E, R211K, F214L, A272P, A288S, V292I, E297N, P313T, V317A, G333E, M357T, R358K, K366R, A376T, T386I, K390R, A400T, V435I, N447S, R461K, Q509H, V548I  
1518 consensus_1518 None None   D123E, I142V, S162T, D177E, I178V, G196E, T200TI, E204EK, R211G, I244V, D250E, A272P, Q278H, I293V, K311R, S322T, T377L, K390R, A400T, I434L, V467I, S468T, A554AT, K558KR  
1619 consensus_1619 None None   T69S, I135T, S162A, Q207E, V245E, T286A, S322T, I326V, I329V, Q334E, I434L, V435E, V467VI, L491S, A554NS  
1709 consensus_1709 None None   E6D, K43N, R83K, K122E, D123E, I135X, S162H, E203D, V245VM, V276VI, Q278QH, T286TA, I293V, T296TS, E297EA, K311KR, I329IL, M357T, K390R, A400T, E404D, D460N, V467I, A508G, E516ED, L517I, S519N, K527KR, A554S  
1799 consensus_1799 None None  K103N K20R, V35I, E42EK, D123E, I135L, E169A, R172K, R211K, A272P, K277R, V292I, I293V, E297A, I309L, S322T, R358K, G359S, T369I, K385R, K390R, A400L, L452I, D460N, V467I, L491P, L517I, S519N, Q524H, V531I, A554T, K558R  
1897 consensus_1897 None None   V118I, K122E, I135T, R211K, F214L, V245E, K277R, V317T, K366R, V381I, E404D, E432D, S468P, H483Y, A554N  
1926 consensus_1926 None None   K20R, V35I, D123E, I135T, P176T, R211E, F214L, V245M, T286A, I293V, E297K, G333E, M357T, R358K, D364E, T377K, T386I, A400T, L452I, D460N, S468P, L491S, K530R, I556V  
2000 consensus_2000 None None   K102Q, K122E, S162C, I178M, T200A, Q207E, R211K, V245E, A272P, K277R, T286A, S322A, Q334D, P345Q, F346Y, M357A, T386I, A400T, F416Y, P421L, D460N, V467I, T470P, L491S, S519N, I556V, K558R  
2008 consensus_2008 None None   D121DY, K122E, S162A, E169D, Q197QE, T200A, R211K, V245IKM, A272P, T286A, I326V, G333E, Q334H, M357T, A360T, A376T, S379C, T403R, V435I, V467I, T470A, K558R  
2136 consensus_2136 None None   R211K, A272S, K281R, Q334E, F346Y, K347R, M357T, T386I, K390R, A400T, T403I, A446S, K512R, A554T, K558R  
2241 consensus_2241 None None   V35I, K102R, K122E, I135T, D177E, I178M, R211K, E291D, I293V, E297T, S379G, V381I, K390R, T470A, L517V, A554T  
2254 consensus_2254 None None   V35I, K122E, I135T, D192N, I202V, K277R, Q278E, T286A, T296S, E297K, G333E, Q334H, R356K, Q367L, T386I, K390R, A400T, V435A, N447S, D460N, R461K, S468T, Q524E, A554N M16Q 
2289 consensus_2289 None None   K49R, I135T, R211K, V245K, D250E, K277R, I293V, E297A, Q334E, M357T, S379G, K390R, A400S, E404D, V435A, A554T  
2305 consensus_2305 None None M41L, T215DE  I178M, G196E, L210LF, I244V, A272P, R284RK, V317A, S322T, G335S, P345EQ, F346HY, R356K, M357T, A376S, T386I, K390R, E399D, A400S, D460N, L491LQ, V531VA, K558KR  
2349 consensus_2349 None None   V118I, I135T, T165I, T200I, F214L, T286A, I329V, A371V, S379G, K390R, A400T, T403A, D460N, R461K, S468T, S519N, A554S  
2437 consensus_2437 None None  V179E K122A, T200I, Q207T, R211K, A272P, T286A, I293V, K311R, I329L, A376S, T386I, A400T, S468P, H483N, A554N, V559I  
2495 consensus_2495 None None  K238T D123E, I135T, D177N, F214L, D237E, V245E, E248D, T286A, P294S, E297K, A376T, K390R, T403A, K451R, L452V, D460N, R461K, S468T, H483Y, Q524E, V531I, A554T, K558R  
2586 consensus_2586 None None   K20R, V35M, K122Q, K166R, K173E, Q174R, D177E, I202V, F214L, V245I, D250E, A272P, K277R, T338S, R356RK, R358K, K366R, A376T, A400T, V435L, T450S, V467I, L469I, H483Y, S519N, Q524E, A554S  
2622 consensus_2622 None None   K32R, V35M, T39A, K104N, D123E, S162C, R211K, F214L, I293V, E297K, V317A, M357T, K390R, E399D, A400I, D460N, V467I, S468P, L491S, K512R, S519N, E529D, K530R  
2649 consensus_2649 None None   E6D, K102KQR, D123E, D177E, F214L, V245M, A272P, K277R, V317A, D324N, I329V, R356RK, A371V, A376S, K390R, V435M, V466A, S468P, H483Y, L517I, S519N  
2667 consensus_2667 None None   K49R, A98S, K122Q, I135V, Q174H, D177E, T200A, V245K, A272P, L283I, P294Q, Q334N, G335D, G359S, K374Q, T377R, K390R, K395R, E432D, D460N, V467I, G490E, S519N, A554S  
2696 consensus_2696 None None   V35T, K43R, V60I, S68G, S162A, K173A, Q174K, D177E, I178M, E203Q, Q207E, R211K, F214L, V245K, K277R, T286A, V292I, I293V, P294T, I326V, G335D, R356K, M357K, R358K, G359S, A371V, K374R, I375V, A376S, K390R, T403R, E432D, S468P, D471E, Q480H, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554S  
2717 consensus_2717 None None   N175Y, G196D, V245I, A272T, I293V, P294T, K311R, I326V, I329V, A371V, T403M, L469I, L517I, A554T  
2794 consensus_2794 None None   K20R, V60I, I135T, G196E, T200E, V245M, A272P, T286A, V292I, E297K, I326V, Q334Y, F346L, M357V, G359S, T403M, L452S, R461K, L469I, H483Y, K512R, E529D, A554S, K558R