<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Rolland (2012)
Title Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2
Citation Nature
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 121
NumPts 121
Subtype CRF01_AE, B, CRF02_AG


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Page 1   from Isolate 1 to Isolate 100 from Total 121 Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
AA001a12L AA001a12L None None   E6D, V35T, T39K, K43E, K122E, D123S, S162C, K173T, Q174K, D177E, T200A, Q207A, R211S, V245E, K249R, T286A, E291D, V292I, I293V, P294S, E312T, I329V, Q334N, G335D, E344D, M357K, G359S, K366R, A371V, A376V, T386A, K395R, A400T, E432D, N447S, D460N, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
AA002a_LH13 AA002a_LH13 None None   V35T, T39K, K43E, K122E, D123S, I135L, S162C, R172K, K173I, Q174K, D177E, I178M, Q207A, R211S, V245E, T286A, E291D, V292I, I293V, P294Q, E312T, D324E, I326V, I329V, G335D, M357R, G359S, K366R, A371V, A400T, E432D, D460N, D471E, Q480H, H483Y, G490E, L491S, K512R, L517I, S519N, Q524E, A534S, A554S H221HR 
AA003b12L AA003b12L None None   E6D, V35T, T39K, K43E, K122E, D123N, T139A, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S, K238R, V245E, A272P, I274V, T286A, V292I, I293V, E312T, I326V, I329V, G335D, Y342F, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E404D, E432D, V435I, N447S, D471E, Q480H, L491S, K512R, S515L, L517V, S519N, Q524E, A534S, A554S  
AA004a_wg1 AA004a_wg1 None None   E6D, V35T, T39E, K122E, D123S, I135T, K173I, Q174K, D177E, I178V, T200I, I202V, Q207A, R211S, F214L, K238R, V245E, K277R, T286A, A288T, E291D, V292I, I293V, E312T, I326V, I329V, G335D, E344D, P345Q, M357K, G359S, K366R, T369A, A371V, K390R, K395R, A400T, E404D, T419I, E432D, V435A, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, K527R, A534S, A554S  
AA005a06L AA005a06L None None   E6D, K11T, V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, I202V, Q207A, R211S, V245E, A272P, K281R, T286A, E291D, V292I, I293V, E312T, I329V, G335D, M357K, G359S, A360T, K366R, T369A, K395R, A400T, T403M, E432D, N447S, D471E, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
AA006a03 AA006a03 None None   E6D, K11A, V35T, T39K, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, Q207A, R211S, K238R, I244V, V245K, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376V, T386A, K390R, E399D, A400T, T403M, E432D, N447S, S468T, D471E, Q480H, L491S, K512R, L517V, S519N, Q524D, K530R, A534S, A554T  
AA007a_WG14 AA007a_WG14 None None   E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, K173R, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, P294Q, E312T, P313T, I326V, I329V, R356K, M357K, G359S, K366R, A371V, T386I, K390R, A400T, T403M, E432D, N447S, Q464K, K465R, V467I, S468T, D471E, Q480H, H483Y, V496I, K512R, L517V, S519N, I522V, Q524E, A534S, A554S  
AA008a_LH15 AA008a_LH15 None None   E6D, K11A, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, S162Y, K166R, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, P243A, V245E, T286A, E291D, V292I, I293V, E312N, I326V, I329V, G335D, K350R, M357K, G359S, K366R, A371V, I375V, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S, I556V, K558R  
AA009b03L AA009b03L None None   E6D, V35T, E36D, T39K, K43E, S68N, K122E, D123N, S162C, T165I, K173I, Q174K, D177E, Q207A, R211S, K238R, V245E, T286A, V292I, I293V, E312T, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390R, K395R, A400T, T403M, E413D, E432D, L452Q, T470S, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, K530S, A534S, A554S  
AA010a_WG11 AA010a_WG11 None None   T39I, D123E, A272P, V276T, T286A, D320N, I326V, Q334L, M357T, T377Q, K390R, S468P, K530R, A554T, K558R  
AA011a09L AA011a09L None None   V35I, S68G, T107S, K122E, V179A, T200E, Q207A, R211K, I244V, A272P, V317G, S322T, I326T, Q334N, A360T, A400T, V435I, N447S, E449D, L452I, D471G, S519N, V531I  
AA012a_LH8 AA012a_LH8 None None   E6D, K11S, V35T, T39K, K43E, V60I, S68G, K122E, D123S, K173A, Q174K, D177E, T200A, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357Q, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, D460N, D471E, Q480H, H483Y, L491P, L517V, S519N, Q524E, A534S, A554S  
AA013a05 AA013a05 None None   E6D, K11T, V35T, T39K, K43E, V60I, A98S, D121H, K122E, I135T, I142V, K173I, Q174K, D177E, Q207A, R211S, V245E, L283I, T286A, E291D, V292I, I293V, P294Q, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, E432D, N447S, D460N, R461K, D471E, Q480H, H483Y, L491S, L517V, S519N, Q524E, A534S, A554S  
AA014a02L AA014a02L None None   E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, K173I, Q174K, D177E, I178M, T200K, Q207A, R211S, K238R, V245Q, A272G, T286A, E291D, V292I, I293V, K311N, E312T, I329V, G335D, M357K, G359S, K366R, A371V, S379G, V381I, K388R, K390R, A400T, K424Q, E432D, N447S, L452Q, V466I, V467I, T470N, D471E, K476Q, Q480H, H483Y, L491S, I505V, K512R, L517V, Q524E, K527R, A534S, A554S  
AA015a_LH1 AA015a_LH1 None None   K11T, V35T, T39K, K43E, S68G, D123S, I159V, K173I, Q174K, D177E, I178M, Q207A, R211S, V245K, T286A, E291D, I293V, K311R, E312T, D324E, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, R448K, D471E, Q480H, L491P, K512R, L517V, S519N, Q524E, A534S, A554S  
AA016a05L AA016a05L None None   E6D, V35T, T39K, K43E, K122E, D123S, K173L, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I329V, G335D, M357K, G359S, K366R, A371V, S379G, K395R, A400T, E432D, N447S, K451R, L452Q, T470S, D471E, Q480H, L491S, K512R, L517I, Q524E, A534S, A554S  
AA017a_wg4 AA017a_wg4 None None   E6D, K11T, V35T, T39K, K43E, D86E, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, K238R, V245E, K249R, V276I, E291D, V292I, I293V, E312T, I329V, G335D, M357K, G359S, K366R, A371V, K385R, K390R, K395R, A400T, T403M, E432D, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, K527N, A534S, V536I, A554S, G555GE  
AA018a05L AA018a05L None None   K11T, V35T, T39K, K43E, K102R, K104R, K122E, D123S, S162C, K173I, Q174K, Q207A, V245E, A272P, I274V, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, K347R, M357R, R358T, G359S, K366R, T369A, A371V, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, E546A, K550N, A554S  
AA019a_WG2 AA019a_WG2 None None   E6D, K11T, K20R, V35T, T39R, K43E, K122E, D123N, I135L, S162N, R172K, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, V245E, A272P, V276I, T286A, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357Q, G359S, K366R, A371V, A376V, T386P, K390R, A400T, E432D, N447S, D460N, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, A534S, V548I, A554S  
AA020a_wg2 AA020a_wg2 None None   E6D, V35T, T39K, K43E, K49R, S68G, K122E, D123S, A158S, S162A, E169D, K173R, Q174K, D177E, T200A, Q207A, R211S, V245E, T286A, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T386I, K395R, A400T, T403M, E432D, N447S, R463K, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, A534S, A554T  
AA021a06L AA021a06L None None   E6D, K11T, V35T, T39K, K43E, K49R, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, I178M, T200R, Q207A, R211S, K238R, V245E, A272P, K281R, T286A, E291D, V292M, I293V, E297Q, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, T377I, K395R, A400T, T409TA, E432D, N447S, R461K, D471E, Q480H, H483Q, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
AA022a_LH7 AA022a_LH7 None None  A98G K11T, V35T, D121H, K122E, D123S, I135L, R172K, K173I, Q174K, D177E, Q207A, R211S, V245K, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357Q, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D460N, V467I, D471E, Q480H, L491P, K512R, L517V, S519N, Q524E, A534S, A554S  
AA023a11L AA023a11L None None   V35T, T39K, K43E, V60I, K122E, D123S, I135L, T165I, R172K, K173R, Q174K, D177E, I178M, T200A, Q207A, R211S, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357N, G359S, K366R, A371V, K388R, K390R, A400T, E404D, E432D, D460N, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, A534S  
AA024a08 AA024a08 None None  V179D E6D, K20R, V35I, T39K, K122E, D123S, I135T, K173I, Q174K, D177E, Q207A, R211S, F214L, V245E, A272G, T286A, I293V, E312T, I329V, G335D, M357K, G359S, V365I, K366R, A371V, I375M, T386I, K390R, A400T, T403M, E432D, V435I, N447S, D471E, Q480H, G490E, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
AA025a_WG9 AA025a_WG9 None None   K122E, D123S, I135T, Q145QR, S162C, K173GR, Q174K, D177E, I178M, Q207A, R211S, P313T, I329L, V365I, T386I, A400T, T403M, E432D, V435I, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S, K558R  
AA026a01L AA026a01L None None   E6D, V8I, K11T, V35T, E36D, T39R, K43E, R83K, D123N, K173I, Q174K, D177E, T200I, Q207A, R211S, V245E, T286A, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, T369A, A371V, A400T, T403M, E432D, N447S, L452V, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
AA027a_wg2a AA027a_wg2a None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, S162Y, K173I, Q174K, D177E, I178M, Q207A, R211S, V245Q, E291D, V292I, E312N, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, V435I, N447S, D471E, Q480H, H483Y, L491S, K512R, L517I, S519N, Q524E, A534S, A554L  
AA028a_wg9 AA028a_wg9 None None   E6D, K11T, K20R, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, Q207A, L209X, R211S, V245E, K249Q, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K395R, A400T, T403M, E432D, V435I, N447S, D471E, H483Y, L491S, K512R, L517V, S519N, Q524E, A534S, E546V, A554S  
AA029b02L AA029b02L None None   E6D, V35T, T39K, K104N, K122E, D123S, S162C, F171Y, K173I, Q174K, D177E, Q207A, R211S, V245E, A272P, I274V, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, K350R, M357K, G359S, K366R, A371V, K390R, A400T, E432D, D471E, Q480H, L491S, K512R, S515L, L517V, S519N, I522V, Q524E, A534S, A554S, I556V T362TA 
AA030a12 AA030a12 None None   V35T, T39K, V60I, K122E, D123S, I135T, T165I, K173T, Q174K, D177E, Q207A, R211N, F214L, V245E, T286A, E291D, V292I, I293V, E297A, A304E, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, D471E, Q480R, H483Q, L491S, K512R, L517V, S519N, Q524K, K527E, A534S, A554S  
AA031a_LH2 AA031a_LH2 None None   I5V, E6D, K11A, V35I, T39N, S68G, K122E, D123N, I135T, S162C, K173T, Q174K, D177E, T200I, I202V, Q207A, R211S, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, Y342F, M357K, G359S, K366R, A371V, K390R, E399D, A400T, T403M, E432D, D471E, Q480H, H483Q, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S Q222R 
AA032a05 AA032a05 None None   E6D, V8I, K11T, V35T, T39K, K43E, S68N, K122E, D123S, I135V, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, I375V, T386I, K388R, K395R, A400T, T403M, E432D, N447S, V458I, S468H, D471E, Q480H, L491S, K512R, L517I, S519N, E523K, Q524E, A534S, A554S  
AA033a_wg4a AA033a_wg4a None None   E6D, K11T, V35T, T39K, K43E, V60I, K122E, D123S, I135T, Q174K, D177E, Q207A, R211S, F214L, V245D, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, M357K, G359S, K366R, A371V, K390R, K395R, A400T, E432D, N447S, R448K, D460N, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
AA034a_wg4 AA034a_wg4 None None   E6D, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, I180IV, Q207A, R211N, K238R, V245E, W252R, T286A, A288T, E291D, V292I, I293V, E312T, P313S, I329V, G335D, M357K, G359S, K366R, A371V, S379G, V381I, K385R, K390R, A400T, T403M, E404D, E432D, N447S, D471E, Q480H, L491S, N494NS, K512R, L517V, S519N, Q524E, A534S, A554T R72K 
AA035a03L AA035a03L None None   E6D, K11T, V35T, T39K, K43E, K49R, K122E, D123S, S162C, Q174E, D177E, I178M, V179I, T200E, E204K, Q207A, R211N, V245E, E248D, K249R, T286A, E291D, V292I, I293V, E297K, A304E, K311R, E312T, I326V, G335D, M357K, G359S, K366R, A371V, E399D, A400T, T403M, E432D, V435I, N447S, L452Q, D471E, Q480H, H483Q, L491P, K512R, L517V, S519N, Q524E, K530R, A534S, A554S  
AA036a05L AA036a05L None None   E6D, K11T, V35T, T39K, K43E, K64R, K122E, D123S, T165I, K173I, Q174K, D177E, I178M, T200A, Q207A, L210M, R211S, K238R, V245E, T286A, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, T377S, S379G, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Y, L491S, A502T, K512R, L517V, S519N, Q524E, A534S, A554S  
AA037a_wg1 AA037a_wg1 None None   E6D, V35T, T39K, K43E, D123S, K173I, Q174K, D177E, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369TA, A371V, K390R, K395R, A400T, P420PS, E432D, D460N, D471E, Q480H, L491P, K512R, L517V, S519N, Q524E, A534S, A554T  
AA038a_WG3 AA038a_WG3 None None   E6D, K20R, V35T, T39K, K43E, K122E, D123S, S162Y, K173X, Q174K, V179I, T200I, E203D, Q207A, R211S, K238R, V245E, A272G, T286A, E291D, V292I, I293V, K311R, E312T, I326V, M357K, G359S, K366R, A371V, S379G, A400T, E432D, N447S, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, A534S, Q547K, A554S  
AA039a07L AA039a07L None None   V35T, T39A, K122E, D123G, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, V245Q, E248N, K275Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, T369A, A371V, I375A, K390R, K395R, A400T, T403V, E432D, D471E, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527E, E529D, V531I, A534S, A554N  
AA040a_WG13 AA040a_WG13 None None   V90I, V111I, I135V, G196E, T200A, I202V, Q207E, F214L, V245E, A272P, K277R, Q278E, P294Q, E297V, P313S, I329V, Q334L, F346Y, A360V, V365I, T369A, I411V, V435E, A437V, D460N, R461K, S468T, V548I  
AA041a01L AA041a01L None None   E6D, V35T, T39K, K102Q, K104R, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207A, R211G, K238R, V245K, A272P, T286A, E291D, V292I, I293V, P294Q, E312T, I329V, G335D, K350R, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, L452Q, D460N, R461K, S468C, D471E, Q480H, H483Y, L491P, K512R, L517I, S519N, Q524E, A534S, A554S  
AA042a07L AA042a07L None None   E6D, V8I, V35T, T39K, K43E, K122E, D123S, K166R, K173I, Q174K, D177E, I178M, V179I, E204K, Q207A, R211S, K238R, V245E, A272P, K281R, T286A, E291D, V292I, E312T, S322A, I329V, G335D, M357K, G359S, K366R, T369A, A371V, V381I, A400T, T403M, E432D, N447S, R448K, L452E, D460N, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
AA044a_LH20 AA044a_LH20 None None   E6D, K11T, V35T, T39K, K43E, K102R, K104N, K122E, D123S, K126R, S162C, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S, V245Q, A272P, T286A, E291D, V292I, I293V, K311R, E312A, I326V, G335D, M357K, G359S, K366R, A371V, K390R, E399D, A400T, T403M, E404D, E432D, N447S, L452Q, D471E, Q480H, L491P, L517V, S519N, Q524E, K527R, K530R, A534S, A554S  
AA045a01L AA045a01L None None   E6D, V35T, T39K, K43E, K122E, D123N, K166R, K173A, Q174R, D177E, Q207A, R211N, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, M357K, G359S, K366R, T369A, A371V, K390R, K395R, A400T, T403M, E432D, V435I, D471E, K476R, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
AA048b12L AA048b12L None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, I135V, K173S, Q174K, D177E, I178M, Q207A, R211S, V245E, K249R, K281R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390R, K395R, A400T, T403M, E404D, E432D, N447S, D471E, Q480H, L491P, K512R, L517V, S519N, Q524E, A534S, A554S  
AA049a_WG11 AA049a_WG11 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200K, Q207A, R211S, K238R, V245E, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D460N, D471E, K476Q, Q480H, L491S, K512R, L517V, S519N, E523G, Q524E, A534S, V548I, A554S  
AA050a_WG2 AA050a_WG2 None None   E6D, E28K, K32E, V35T, T39K, S162C, K173T, Q174K, D177E, I178V, V179I, E194K, G196E, Q207A, R211S, K238R, V245E, A272S, E291D, V292I, I293V, L310I, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, S468X, D471E, H483Y, L491S, K512R, E514D, L517V, S519N, Q524E, E529D, A534S, A554S  
AA051b03L AA051b03L None None   E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, K173R, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, P294Q, E312T, P313T, I326V, I329V, M357K, G359S, K366R, A371V, T386I, K390R, A400T, T403M, E432D, N447S, Q464K, K465R, V467I, S468T, D471E, Q480H, H483Y, K512R, L517V, S519N, Q524E, A534S, A554S  
AA052a01 AA052a01 None None  Y181C E6D, K11T, V35T, T39K, K43E, K122E, D123S, I135M, S163C, K173L, Q174K, D177E, I178M, Q207A, R211S, I244V, V245E, A272P, T290TA, E291D, V292I, I293V, E297A, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, E399D, A400T, T403M, N447S, V466A, D471E, Q480H, L491S, K512R, L517I, Q524E, A534S, A554S  
AA054a04 AA054a04 None None   E6D, K11A, V35T, T39K, K43E, D123N, K173A, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, K281R, T286A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K395R, A400T, T403M, E432D, N447S, D471E, L491S, K512R, L517V, S519N, Q524E, A534S, A554S, K558R  
AA055a_WG3 AA055a_WG3 None None   E6D, V8I, K11A, V35T, T39K, K43E, K122E, D123N, I135T, S162N, K173I, Q174K, D177E, T200A, Q207A, R211N, K238R, V245S, S251H, E291D, V292I, I293V, E312T, I326V, I329V, G335D, R356K, M357K, G359S, K366R, E370D, A371V, K390R, A400T, T403M, E432D, V435L, L452Q, V466A, D471E, Q480H, L491P, K512R, L517V, S519N, Q524E, K527R, A534S, A554S  
AA056a_WG6 AA056a_WG6 None None   E6D, K11T, V35T, T39K, K43E, V60I, K122E, D123S, I142V, K173I, Q174K, D177E, I178M, T200R, Q207A, R211S, K238R, V245K, T286A, E291D, V292I, I293V, R307K, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, D471E, Q480H, H483Y, L491V, K512R, L517V, S519N, Q524E, A534S, A554S  
AA057a07L AA057a07L None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, T165I, Q174K, D177E, Q207A, R211S, K238R, V245K, A272P, K275R, T286A, E291D, V292I, I293V, E312T, L325I, I326V, I329V, G335D, M357K, G359S, A371V, K374R, T386I, K390R, A400T, T403M, E432D, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
AA058a02L AA058a02L None None   E6D, K11T, V35T, T39K, K43E, V60I, K122E, D123S, I142V, K166R, K173I, Q174K, D177E, T200I, I202V, Q207A, R211K, V245E, A272P, K281R, T286A, E291D, V292I, I293V, E312T, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390R, K395R, A400T, T403M, E432D, N447S, R461RK, V466I, D471E, Q480H, H483Q, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
AA059a_WG3 AA059a_WG3 None None   E6D, V35T, T39K, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, K249R, S251I, A272G, T286A, E291D, V292I, I293V, P294Q, E298G, E312T, I326V, I329V, G335D, K350R, M357K, G359S, K366R, A371V, K390R, A400T, E432D, N447S, D471E, Q480H, L486X, L491X, K512R, L517V, S519N, Q524E, A534S Q487d, D488d, S489d, G490d 
AA060a_WG8 AA060a_WG8 None None   V35T, T39K, K43E, K122E, D123S, K173I, Q174K, T200A, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, I375V, T377L, K390R, I393IT, K395R, A400T, T403M, E432D, N447S, L452V, R461K, D471E, Q480H, H483Y, L491S, K512R, E514D, L517I, S519N, Q524E, A534S, A554S  
AA061a10L AA061a10L None None   E6D, K11T, V35T, T39K, K43E, K64R, K122E, D123S, K173M, Q174K, D177E, I178V, Q207A, R211S, V245E, A272P, K281R, T286A, E291D, V292I, I293V, E312T, D324E, I329V, G335E, R356K, M357K, R358K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, R448K, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
AA062b03L AA062b03L None None   E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, V276I, E291D, V292I, I293V, E312T, V317A, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T386I, K390R, K395R, A400T, T403M, E432D, N447S, T470S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
AA063a_WG35 AA063a_WG35 None None   E6D, K11T, V35T, T39K, V111I, K122E, D123S, S162C, K173I, Q174K, D177E, Q207A, R211S, F214L, V245E, T286A, I293V, E312N, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, V435I, N447S, D471E, Q480H, H483Q, L491S, K512R, S515L, L517V, S519N, Q524E, A534S, A554S  
AA064a_WG4 AA064a_WG4 None None   E6D, K11T, V35T, T39K, K43E, G45X, K46X, K122E, D123S, I135T, I142V, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, A371V, T386I, K390R, A400T, T403M, E432D, N447S, R448K, D460N, D471E, Q480H, H483Y, L491S, K512R, L517I, Q524E, A534S, A554S  
AA065a07L AA065a07L None None   E6D, K11A, V35T, T39K, K43E, K122E, D123N, I135T, S162A, E169A, K173T, Q174R, D177E, I202V, Q207D, R211N, V245K, K249Q, A272G, K281R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, K476Q, Q480H, L491P, K512R, L517V, S519N, Q524E, A534S, A554S  
AA066a07L AA066a07L None None   E6D, V35T, T39K, K43E, V60I, K66R, S68G, K122E, D123S, I135V, I142V, K173V, Q174K, D177E, I178M, Q207A, R211S, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
AA067a_WG13 AA067a_WG13 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, R356K, M357K, G359S, T369A, A371V, K390R, K395R, A400T, E432D, D460N, R461K, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
AA068a_23 AA068a_23 None None   E6D, V8I, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135V, K173I, Q174E, D177E, I178M, V179I, T200A, Q207T, R211K, K238R, V245E, K249R, S251H, T286A, E291D, V292I, I293V, P294Q, E312T, I326V, I329V, G335D, R356K, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E404D, E432D, N447S, R448K, D460N, T470S, D471E, Q480H, H483Y, L491S, K512R, L517I, S519N, Q524E, A534S, A554T, K558R  
AA069a02L AA069a02L None None   E6D, K11T, V35T, T39K, K43E, A98S, K122E, D123S, I135R, K173I, Q174K, D177E, T200A, Q207A, R211S, K238R, V245E, E291D, V292I, I293V, E312T, V314M, I329V, G335D, M357K, G359S, K366R, A371V, A400T, E432D, N447S, D460N, T470A, D471E, Q480H, L491S, I506L, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
AA070a_LH07 AA070a_LH07 None None   E6D, K11A, V35T, T39K, K43E, K122E, D123S, K166R, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, A272P, K275R, V276I, K281R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, M357K, G359S, K366R, T369A, A371V, I375V, K395R, A400T, E404D, E432D, V435L, N447S, D471E, K476Q, Q480H, H483Q, L491S, K512R, E516D, L517I, S519N, Q524E, K527R, A534S, A554S H221HR 
AA072a05 AA072a05 None None   E6D, V35T, T39K, K43E, V60I, S68G, K103R, K122E, D123S, I135T, S162C, K173S, Q174K, D177E, Q207A, V245E, A272P, T286A, E291D, V292I, I293V, K311T, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, I380V, T386A, K390R, K395R, A400T, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S P55PL 
AA073a_LH5 AA073a_LH5 None None  Y181C, P225H E6D, K11S, K20R, V35T, T39K, V111I, K122E, D123N, R172K, K173I, Q174K, D177E, I178L, Q207A, V245K, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, K350R, M357K, G359S, K366R, A371V, A376V, T386A, K390R, A400T, E432D, R461K, D471E, Q480Y, H483Q, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
AA074a01L AA074a01L None None   E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123N, I135T, K173V, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I329V, G335D, M357Q, G359S, K366R, A371V, I382L, K390R, K395R, A400T, T403M, E432D, V435I, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
AA075a_WG2 AA075a_WG2 None None   E6D, V35T, T39K, K43E, K122E, D123S, S162C, K173I, Q174K, D177E, V179I, T200A, Q207A, R211S, K238R, V245K, A272P, K281R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369V, E370D, A371V, T377I, K390R, A400T, T403M, E432D, K451R, D460N, D471E, Q480H, H483Y, L491T, K512R, L517V, S519N, Q524E, A534S, A554S  
AA076a01L AA076a01L None None   E6D, V35T, T39K, K43E, K122E, D123S, K166R, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, V276I, T286A, E291D, I293V, A304E, E312I, I329V, G335D, Y342F, M357K, G359S, K366R, T369A, K390R, K395R, A400T, T403M, E404K, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
AA077a_LH33 AA077a_LH33 None None   E6D, K20R, V35T, E36A, T39K, K43E, K122E, D123N, I135T, S162C, K173A, Q174K, D177E, I178M, T200I, Q207A, R211S, F214L, V245E, V276I, T286A, E291D, V292I, E312T, S322A, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, E432D, L452Q, D460N, D471E, K476Q, Q480H, L491S, L517V, S519N, Q524E, A534S, A554T G18E, G262E 
AA078a06L AA078a06L None None   E6D, K11T, V35T, E36D, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, T200I, E203D, Q207A, R211S, V245E, T286A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390R, K395R, A400T, T403M, E404D, E432D, N447S, L452Q, D471E, Q480H, L491S, K512R, L517V, Q524E, A534S, A554T G462GR 
AA079a_WG1 AA079a_WG1 None None   E6D, V35T, T39E, K122E, D123S, T139A, T165K, K173A, Q174K, Q207A, R211S, K238R, V245E, T286A, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E404D, E432D, N447S, L452I, D471E, Q480H, L491S, K512R, L517V, Q524E, A534S, A554S  
AA080a13L AA080a13L None None   V35T, T39K, K43E, K122E, D123S, S162C, K173I, Q174K, D177E, T200I, Q207A, R211S, K238R, I244V, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A400T, T403M, N447S, D471E, Q480H, H483Q, S489A, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
AA081a_01L AA081a_01L None None   E6D, V35T, T39K, K43E, S162C, K173I, Q174K, D177E, Q207A, R211S, K238R, V245E, K249R, V276I, K281KR, T286A, E291D, I293V, E312T, I326V, I329V, G335D, T338S, Y342F, K350R, M357K, G359S, K366R, A371V, K390R, K395R, E399D, A400T, T403M, E432D, N447S, D471E, Q480H, I482V, L491S, A502V, K512R, E514D, L517I, S519N, Q524E, A534S, A554S  
AA082a_WG9 AA082a_WG9 None None   E6D, V35T, T39E, K122E, D123S, I135T, K154R, K173I, Q174N, D177E, T200A, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, E312T, I326V, I329V, G335D, Y342F, M357K, G359S, K366R, T369A, K390R, K395R, A400T, E432D, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
AA083a10L AA083a10L None None   E6D, V8I, K11T, V35T, T39K, K43E, K122E, D123S, I135T, K173I, Q174K, D177E, Q207A, R211S, V245E, T286A, E291D, V292I, I293V, K311S, E312T, K323Q, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T386I, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, I506L, K512R, L517V, S519N, Q524E, A534S, A554S  
AA084a_wg4 AA084a_wg4 None None   K32I, V35T, T39K, S68G, K122E, D123S, I135R, I142T, S162N, K173I, Q174K, R199K, T200I, Q207S, R211S, K238R, V245E, T286A, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359T, K366R, T369A, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524D, A534S, A554S  
AA085a_wg10 AA085a_wg10 None None   K11T, V35T, T39R, K43E, K64R, K102R, V106I, K122E, D123S, S162C, K173R, Q174R, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390R, K395R, E399D, A400T, T403M, E432D, V435L, N447S, D471E, Q480H, L491S, K512R, S515A, L517V, S519N, Q524E, A534S, A554S  
AA086a02L AA086a02L None None   E6D, V35T, T39K, K43E, K102Q, V111I, V118A, K122E, D123N, K166R, K173I, Q174K, Q207A, R211S, K238R, V245Q, T286A, E291D, I293V, E312N, I326V, I329V, G335D, P345Q, R356K, M357K, G359S, K366R, A371V, K390R, A400T, E432D, V435T, L469I, D471E, Q480H, H483Y, L491S, K512R, S515L, E516D, L517V, S519N, Q524E, E529D, A534S, A554S  
AA088a_wg12 AA088a_wg12 None None   E6D, K11A, V35T, T39K, K43E, V60I, K122E, D123S, K173T, Q174K, D177E, I178M, Q207A, R211S, V245E, E248D, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T386I, K390R, E399D, A400T, T403M, E432D, N447S, D471E, L491S, L517V, S519N, Q524E, I526V, A534S, A554S  
AA089a01 AA089a01 None None   E6D, V35T, T39K, K43E, V60I, K122E, D123S, T165I, K173T, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S, K238R, V245E, I274V, T286A, E291D, V292I, I293V, P294T, E312I, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, K527N, A534S, A554S, K558KE  
AA090a_WG5 AA090a_WG5 None None   E6D, V8I, K11T, V35T, T39K, K43E, K122E, D123S, K173L, Q174K, P176S, T200A, Q207A, R211S, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326L, G335D, M357K, G359S, K366R, A371V, I375V, T377M, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, K512R, L517V, S519N, Q524E, E529D, A534S, A554S G18R, S268SG, G316R, T472A 
AA091a03L AA091a03L None None   E6D, V35T, T39K, K43E, K122E, D123S, S162C, E169D, K173A, Q174K, D177E, Q207A, R211S, K238R, V245E, A272P, V276I, T286A, E291D, V292I, I293V, E297G, K311R, E312T, I329V, G335D, M357K, G359S, K366R, A371V, A376S, V381I, K390R, K395R, A400T, T403M, E432D, N447S, D460N, D471E, Q480H, H483Y, L491S, K512R, L517I, S519N, Q524E, A534S, A554T  
AA092b06L AA092b06L None None   E6D, V35M, T39K, K43E, K122E, D123S, I142V, S162C, K173R, Q174K, D177E, T200I, E203D, Q207A, R211S, K238R, V245E, E248D, K249Q, K281R, T286A, E291D, I293V, E312T, I326V, I329V, G333E, M357N, G359S, K366R, A371V, V381I, K390R, K395R, A400T, T403M, E432D, E449D, D471E, Q480H, H483Q, L491P, L517V, Q524E, K530R, A534S, A554S K512MR 
AA093a_LH9 AA093a_LH9 None None   K122E, I135V, S162C, V245L, E248D, Q278E, E312A, D324E, Q334L, P345Q, F346Y, K366R, K390R, E432D, V435E, D460N, R461K, S468T, H483Q, L491S, Q507H, L517I, K527N, E529G, V548I, I556V  
AA094b09L AA094b09L None None   E6D, K11T, V35T, T39K, K43E, V111I, D121H, K122E, D123S, S162C, K173I, Q174K, D177E, V179I, I202V, Q207A, R211S, V245E, S251H, A272P, T286A, E291D, V292I, I293V, E297G, E312T, D324E, I329V, G335D, P345Q, M357N, G359S, T362N, K366R, A371V, K390R, K395R, A400T, T403M, E404D, E432D, V435I, L452I, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554T  
AA095a_WG22 AA095a_WG22 None None   E6D, K11S, V35T, T39K, K43E, K122E, D123S, K173A, Q174K, Q207A, R211S, V245E, K249Q, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, R448K, D471E, Q480H, L491S, E492Q, K512R, L517V, S519N, Q524K, K527Q, A534S, A554S L295LP 
AA096a_WG8 AA096a_WG8 None None  V108I E6G, K11S, V35T, T39K, K43E, K122E, D123S, K173A, Q174K, Q207A, R211S, V245E, K249Q, K277R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, V435E, N447S, R448K, D471E, Q480H, L491S, E492Q, K512R, L517V, S519N, Q524E, K527Q, A534S, A554S  
AA097a01L AA097a01L None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, I142V, K173I, Q174K, D177E, Q207A, R211S, V245E, V276I, T286A, E291D, V292I, I293V, P294S, E312N, I329V, G335D, P345Q, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D460N, R461K, S468T, D471E, T477A, Q480H, H483Q, L491S, K512R, L517I, S519N, Q524E, V531I, A534S, A554S  
AA098a02L AA098a02L None None   E6D, V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, T286A, E291D, I293V, P294T, E312T, S322Q, I326V, I329V, G335D, Y342F, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517I, Q524E, A534S, A554S  
AA099a_WG10 AA099a_WG10 None None   E6D, K11T, V35T, T39K, K43A, S68G, K122E, D123N, I135T, K166R, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, V276I, E291D, I293V, A304E, E312T, I326V, I329V, G335D, K347R, K350R, M357K, G359S, K366R, A371V, K385R, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517I, S519N, Q524E, A534S, A554S, K558R  
AA100b07L AA100b07L None None   E6D, V8I, K11T, V35T, T39K, S68G, K122E, D123S, K173I, Q174K, D177E, I178V, T200I, Q207A, R211S, K238R, V245E, A272P, K277R, T286A, E291D, V292I, I293V, E312T, I329V, G335D, K350R, M357K, G359S, K366R, A371V, I375V, K395R, A400T, T403M, E432D, V435A, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, E546D, A554S  
AA101a_WG1 AA101a_WG1 None None   E6D, V8I, K11T, V35T, K122E, D123S, K126R, I135IV, K173I, Q174K, D177E, V179I, T200I, Q207A, R211S, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E312N, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A400T, T403M, E404D, E432D, N447S, D460N, D471E, Q480H, H483Y, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
AA102a_LH7 AA102a_LH7 None None   E6D, V35T, T39K, K43E, K49R, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, A304E, E312T, D324E, I326V, I329V, G335D, Y342F, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, E529D, V531I, A534S, V548I, A554S  
AA103a07L AA103a07L None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245E, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400L, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
AA104a_LH21 AA104a_LH21 None None   E6D, K11T, V35T, T39K, K43E, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, K281R, T286A, E291D, V292I, I293V, E297K, E312T, P321S, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, L452I, D471E, Q480H, D488E, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S  
AA105a07L AA105a07L None None   E6D, V35T, T39K, K43E, K122E, D123S, I135V, T165I, F171Y, K173R, Q174K, D177E, G196E, Q207A, R211S, K238R, V245E, A272G, T286A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, I375V, T377L, K388R, K395R, A400T, N447S, T470N, D471E, Q480H, H483Q, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
AA106c02L AA106c02L None None   E6D, K11T, V35T, T39K, K122E, D123S, S162N, K173I, Q174K, D177E, I178V, T200A, Q207A, R211S, V245E, E291D, V292I, K311R, E312T, S322A, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, V435I, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, I526V, E529K, A534S, A554S