<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Parczewski (2012)
Title HIV-1 integrase resistance among antiretroviral treatment naive and experienced patients from northwestern Poland.
Citation BMC Infect Dis
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 112
NumPts 77
Subtype B, D, CRF01_AE, C, J, CRF02_AG, G


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Page 1   from Isolate 1 to Isolate 100 from Total 112 Clinical IN Isolates

SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
103 103_38 None    E11D, R20K, G70D, L101I, S119R, T124N, G193E, S195T, T206S, D270N  
  103_39 RAL 12   E11D, R20K, G70D, L101I, S119R, T124N, G193E, S195T, T206S, D270N  
  103_40 RAL 39   E11D, R20K, G70D, L101I, S119R, T124N, G193E, S195T, T206S, D270N  
  103_41 RAL 54   E11D, R20K, G70D, L101I, S119R, T124N, G193E, S195T, T206S, D270N  
  103_42 RAL 84 G140S, Q148H  E11D, R20K, G70D, I73IV, L101I, S119R, T124N, G193E, S195T, T206S, T218TS, D270N  
  103_43 RAL 96 G140S, Q148H  E11D, R20K, G70D, L101I, S119R, T124N, G193E, S195T, T206S, T218TS, D270N  
  103_46 RAL 145 G140S, Q148H  E11D, R20K, G70D, L101I, S119R, T124N, T125TS, G193E, S195T, T206S, T218TS, D270N  
  103_49 RAL 180 G140S, Q148H  E11D, R20K, G70D, K71KR, L101I, S119R, T124N, T125TS, G193E, S195T, T206S, T218S, D270N  
110_45 110_45 None    E11D, S57SN, I60IM, G70E, L101I, S119R, T124N, G193E, S195T, T206S, D279G  
121_27 121_27 None    V32I, S39C, L101I, K111T, S119G, T124N, T125A, E157Q, K160Q, Q177L, V201I, S230N, L234I, D253DE, S255ST  
133_40 133_40 None   V151I K7R, I72V, V77I, S119P, T124A  
157_1 157_1 None    S17N, S57SN, G59GE, I72V, S119P, V201I  
20 20_10 None    E11ED, S17C, M50L, I72V, T112A, I113IV, T124TA, T125A, G193E, V201I, I203M, T218I, L234V, D256E  
  20_51 None    S17N, M50L, I72V, T112A, I113IV, T125A, G193E, V201I, I203M, L234V, D256E D286DN 
  20_55 RAL 80   S17N, S24SN, M50L, I72V, L101LI, T112A, T125A, G193E, V201I, I203M, L234V, D256E A276AG, D286DN 
  20_59 RAL 144   S17N, M50L, I72V, L101LI, T112A, T125A, G193E, V201I, I203M, L234V, D256E D286DN 
  20_62 RAL 203   S17N, M50L, I72V, L101LI, T112A, T125A, G193E, V201I, I203M, L234V, D256E D286DN 
235_1 235_1 None    K14KR, L28LI, P30S, L101I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218TS, Y227F, L234I, S255N, D256E S283G 
238_12 238_12 None    E10G, K14KR, S39C, L101I, T112I, T125A, E157Q, K160Q, V201I, S230N, L234I, D253E, N254D, D256E, V259VI  
258_1 258_1 None    E10D, M50L, I72V, I84M, T112V, I113V, T124A, T125A, G163V, V201I, I203M, T218TI, L234V, D256E  
26_5 H 26_5 H None    E11D, D25E, V31I, I72V, Y99F, L101I, K103KR, K111KT, S119P, T122I, T124A, T125A, G134N, I135V, K136T, R187K, K188R, I200L, V201I, T206S, L234I, S255N, R269K S283G 
286_21 286_21 None    D6E, S17N, I72V, Y99F, L101V, K111R, T112TA, S119G, T122I, T124S, T125A, V201I, K211R, K219Q, D232DN W235W* 
297_2 297_2 None    L101I, T112I, I113IV, T125M, E157Q, K160Q, G163V, V201VI, S230N, L234I, A265V  
307 307_12 None    E10D, L101I, T112I, I113IV, T124N, T125A, E157Q, K160Q, K219T, I220L, S230N, L234I, D253E, D256E, D278G  
  307_18 RAL 196 N155H  E10D, L101I, T112I, T124N, T125A, E157Q, K160Q, K219T, I220L, S230N, L234I, D253E, D256E, D278G  
  307_x RAL 201 N155H  E10D, L101I, T112I, T124N, T125A, E157Q, K160Q, K219T, I220L, S230N, L234I, D253E, D256E, D278G  
  307_19 RAL 218 N155H  D3DE, D6N, K7KQ, E10D, E13ED, N18NY, W19X, M22MI, F26X, L101I, T112I, T124N, T125A, E157Q, K160Q, K219T, I220L, S230N, L234I, D253E, D256E, D278G F1FS, R20RT, L74LF 
409_6 409_6 None    E11D, S24N, D25DE, V31I, I60L, G70N, L101I, T112TI, I113V, T124N, T206S, K211R, A265V  
414_18 414_18 None    E10D, L101I, T112I, T124TA, E157Q, K160Q, S230N, L234I, D253E, D256E R284RG 
431_30 431_30 None    D6E, E10D, V32I, S39SC, L101I, T112M, S119G, T124N, E157Q, K160Q, S230N, L234I  
467_1 467_1 None    M50L, I72V, T112V, I113V, T124A, T125A, V201I, I203M, L234V, D256E  
485_1 485_1 None    S17N, T124A, E157Q, K160Q, Q216QH, S230N, L234I, A265V  
48_34 48_34 None    S17N, I72IV, K111Q, S119G, T122I, T124S, T125A, K211R  
497_21 497_21 None    V31VIM, V32I, L101I, T112I, E157Q, K160Q, V201I, L234I, D253E, D256E  
502_17 502_17 None    E11D, V31I, L101I, S119P, T122I, T125A, G163E, H171L, I182V, T218S, I220L, Q221H, N222A A8AT, G47GR 
504_1 504_1 None   E138D S17N, M50L, I72V, T112V, I113V, T124A, T125A, V201I, I203M, L234V, D256E V260VIM, R284RG 
507_1 507_1 None    V31VI, V32VI, I72V, K111KR, T124TA, T125TA, V201I, T206TA, S230N  
508_1 508_1 None   E138D S17N, M50L, I72V, T112V, I113V, T124A, T125A, V201I, I203M, T218I, L234V, D256E  
514_15 514_15 None    P30A, I72V, K160KN, V201I, T206S  
517_4 517_4 None    S17N, L101I, T112I, T125TA, E157Q, K160Q, S230N, L234I, A265V  
518_4 518_4 None    E10ED, L101I, T112I, E157Q, K160Q, K211R, K219T, I220L, S230N, L234I, D253E, D256E  
520_4 520_4 None    E11D, S17N, I84M, L101I, T112I, E157Q, K160Q, I220L, S230N, L234I, D253E, D256E  
524_1 524_1 None   V151I K7R, E11D, M50MI, I72V, S119P, T124A, I135IV, S195T L101LF 
546 546_15 None    E11D, M50L, I72V, T112V, I113V, T122I, T125A, D167E, V201I, I203M, T218I, L234I, D256E W132W* 
  546_25 RAL 165   E11D, A21AT, S24SN, M50L, K103KR, T112V, I113V, S119SG, T122I, T125A, V165I, V201I, I203M, T218I, L234I, D256E  
549 549_18 None    I72IT, L101I, T112I, E157Q, K160Q, K215KN, S230N, L234I, A265V  
  549_24 RAL 94   P90PS, L101I, T112I, E157Q, K160Q, K215KN, S230N, L234I, A265V  
  549_25 RAL 122   L101I, T112I, E157Q, K160Q, K215KN, S230N, L234I, A265V S283SG 
558_1 558_1 None    C56S, I72V, T112V, I113V, T124A, T125A, G134D, V201I, I203M, T218I, L234V L101LF 
559_2 559_2 None    M50ML, I72V, L101I, K111Q, T112V, I113V, T124TA, V201I, I203M, T218TI, L234V, D256E  
561_17 561_17 None    I72V, T112V, T124A, E157Q, K160Q, R187K, S230N H78HY 
562_2 562_2 None    E11D, M50L, I72V, T112V, I113V, S119G, T122I, T125A, D167E, V201I, I203M, T218I, L234I, D256E  
573_2 573_2 None   T97TA S17N, I72V, L101V, T112I, T125A, E157Q, K160Q, V201I, K211Q, I217V, S230N, L234I, A265V  
575 575_20 None    K14R, V31I, I72V, K111R, T112I, I113V, T124A, T125A, K136Q, D167E, V201I, R231RK, D232DN S283G, R284RK 
  575_14 RAL  R263RK K14R, V31I, I72V, K111R, T112I, I113V, T124A, T125A, K136Q, D167E, V201I, R231RK, D232DN D253DN, S283G 
590_1 590_1 None   L68V L101I, T125TA, E157Q, K160Q, K188KR, G193GR, K211R, K219T, I220L, L234I, D253E, D256E, A265AV  
60 60_24 None    L101I, T112I, E157Q, K160Q, I200L, S230N, L234I, A265V  
  60_40 RAL 246   L101I, T112I, E157Q, K160Q, K173R, I200L, V201I, S230N, L234I, L242LF, A265V  
  60_42 RAL 290   L101I, T112I, E157Q, K160Q, K173R, I200L, V201I, S230N, L234I, A265V S119SN, G277GD 
  60_45 RAL 362   L101I, T112I, E157Q, K160Q, K173R, I200L, V201I, S230N, L234I, A265V  
643 643_1 None    K7Q, E11D, E13D, I72V, T112A, I113V, T124A, T125A, G193E, V201I, I203M, L234V, D256E D286N 
  643_6 RAL 92  L74LIM K7Q, E11D, E13D, I72AV, T112AV, I113V, T124A, T125A, E170EA, G193E, V201I, I203M, L234V, D256E D286N 
  643_15 RAL 223   K7Q, E11D, E13D, A23AV, I72V, I84M, T112A, I113V, T124A, T125A, G193E, V201I, L234V, D256E A8AV, I73IF, D286N 
  643_17 RAL 251   K7Q, E11D, E13D, I72V, I84M, T112A, I113V, T124A, T125A, G193E, V201I, L234V, L242LF, D256E D286N 
  643_18 RAL 261   K7Q, E11D, E13D, I72V, I84M, T112A, I113V, T124A, T125A, G193E, V201I, L234V, D256E D286N 
  643_19 RAL 280   K7Q, E11D, E13D, I72V, I84M, T112A, I113V, T124A, T125A, G193E, V201I, L234V, D256E D286N 
645 645_1 None  P145PS  E11D, M50L, T112V, I113V, K173R, V201I, I203M, L234V, D256E  
  645_20 RAL 270 N155H  E11D, A21T, M50L, P90PS, T112V, I113V, K173R, V201I, I203M, I208L, D232DN, L234V, D256E  
  645_21 RAL 292 E92EQ, N155H V151VI, G163GR E11D, A21T, M50L, T112V, I113V, K173R, V201I, I203M, I208L, D232DN, L234V, D256E Q44Q*, D253DN 
678_1 678_1 None    D25E, V31I, M50L, I84M, F100Y, L101I, T112V, T124TA, T125A, K136Q, V201I, K215N, L234I, R269RK, D278A S283G 
682_12 682_12 None    K14R, L101I, E157Q, K160Q, G193D, I208M, L234I, N254NK, A265V, D278DE D286N 
69 69_10 None    S17N, M50L, I72V, G106A, T112V, I113V, T124A, T125A, V201I, I203M, L234LV, D256E  
  69_58 RAL 613 N155H  S17N, M50L, I72V, G106A, K111N, T112I, I113IV, T124A, T125A, I141IV, R187RK, V201I, I203M, D232N, D256E E85EA 
  69_59 RAL 634 N155H V151VI S17N, M50L, I72V, G106A, K111N, T112I, I113V, T124A, T125A, V201I, I203M, D232N, D256E  
  69_60 RAL 648 N155H V151I S17N, M50L, I72V, G106A, K111N, T112I, I113V, T124A, T125A, V201I, I203M, D232N, D256E L101LF 
708_1 708_1 None    S17N, G59E, L101I, T112A, T125A, V201I, I208L, S230SN, D256E H16HY, V281M 
711_1 711_1 None    E11D, M50L, C56S, I72V, T112V, I113V, T124A, V201I, I203M, T218TI, L234I, D256E  
727_8 727_8 None    K14R, L28I, L101I, H171L, V201VI, I208L, T218S, I220L  
743_1 743_1 None    E11D, M50L, C56S, I72V, G106A, T112V, I113V, T124A, G134GD, V201I, I203M, I208IL, K211KR, T218TI, L234V, D256E  
744_1 744_1 None   L68LI E11D, M50L, C56S, I72V, T112V, I113V, T124A, H171HQ, V201I, I203M, T218I, L234I, D256E  
748_1 748_1 None    E11D, R20RK, M50L, C56S, I72V, T124A, G193E, V201I, I203M, T218TI, L234V, D256E D288N 
766_1 766_1 None    E11D, M50L, C56S, I72V, T112V, I113V, V201I, I203M, T218I, L234I, D256E  
781_1 781_1 None    E11D, M50L, C56S, I72V, K111KR, T112V, I113V, V201I, I203M, T218TI, L234I, D256E  
787_1 787_1 None    S17N, A21T, M50L, I72V, T112A, T125A, G193E, V201I, I203M, L234V, D256E, Q285* D286N 
828 828_1 None    E10D, M50I, L101I, T112I, E157Q, K160Q, S230N, L234I, D253E, D256E  
  828_7 RAL 82   E10D, M50I, L101I, T112I, E157Q, K160Q, S230N, L234I, D253E, D256E  
  828_8 RAL 107   E10D, M50I, L101I, T112I, E157Q, K160Q, S230N, L234I, D253E, D256E  
837_1 837_1 None    E11D, K14KR, M50L, C56S, I72V, T112V, I113V, T124A, V201I, I203M, L234I, D256E  
853_1 853_1 None    K14R, D25E, V31I, F100W, L101I, T112V, S119T, T124A, T125A, K136Q, V201I, I204L, K211KT, L234I, A265AV, R269K, D278A S283G 
874_2 874_2 None    V37I, E96D, L101V, T112I, T124N, T125A, E157Q, K160Q, S230N, L234I, D253E  
893_1 893_1 None    K7KR, R20K, L101I, K111KR, T112I, T125A, V126A, E157Q, K160Q, G193E, S230N, L234I, D253E  
894_1 894_1 None    E11ED, D41DN, M50L, C56S, I60V, I72V, K111KR, T112V, I113IV, T124A, R187RK, V201I, I203M, T218I, Y227YN, L234I, S255SG, D256E K188KT, R262RS 
900_1 900_1 None    E11ED, M50L, C56S, L63LV, I72V, T112V, I113V, S119P, T122I, T124N, V201I, I203M, K211KR, T218TI, L234V, D256E  
907_1 907_1 None    S17N, I72V, T124N, T125A, V126L, K188KR, G193GE, S230N, D256E  
911 911_1 None    E11D, M50L, C56S, I72V, T112V, I113V, V201I, I203M, L234I, D256E  
  911_5 RAL 70   E11D, M50L, C56S, I72V, T112V, I113V, V201I, I203M, L234I, D256E  
  911_6 RAL 91   E11D, M50L, C56S, I72V, T112V, I113V, V201I, I203M, L234I, D256E  
912_1 912_1 None    E11D, K14R, A21T, V31I, M50I, T125TA, S230N, R231K L2LF, H12HP, T124TADN 
931_1 931_1 None    E11D, R20K, M50L, C56S, I72V, T112V, I113V, T124A, V201I, I203M, T206TS, L234V, D256E  
934_1 934_1 None    A49P, M50L, C56S, I72V, T112V, I113V, V201I, I203M, T218TI, L234I, D256E