<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Villena (2007)
Title Relative fitness and replication capacity of a multinucleoside analogue-resistant clinical human immunodeficiency virus type 1 isolate with a deletion of codon 69 in the reverse transcriptase coding region.
Citation J Virol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 5
NumPts 1
Subtype B


Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
36708 36708-1 D4T, 3TC, DDI None A62V, K70G, V75I, F77L, Y115F, F116Y, Q151M, M184V Y181C K20R, T39A, S68G, T69A, K101R, D123E, I135T, I167V, D177E, I202V, R211K, I293V, P294T, E297K, I375V, T386I, V435I, E449D, D460N, S468P, L491S, K512T, L517I, S519N  
  36708-2 D4T, 3TC, DDI, ABC EFV A62V, K70G, V75I, F77L, Y115F, F116Y, Q151M, M184MV K103N, Y181C, G190A T39A, S68G, T69A, K101R, D123E, I135T, I167V, D177E, I202V, R211K W71W* 
  MDRc3
Consensus 
D4T, 3TC, DDI, ABC EFV A62V, K70G, V75I, F77L, Y115F, F116Y, Q151M, M184V K103N, Y181C, G190A K20R, T39A, S68G, T69A, K101R, D123E, I135T, I167V, D177E, I202V, R211K, I293V, P294T, E297K, M357T, I375V, T386I, V435I, E449D, D460N, L491S, K512T  
  MDRc7
Consensus 
D4T, 3TC, DDI, ABC EFV A62V, V75I, F77L, Y115F, F116Y, Q151M, M184V K103N, Y181C, G190A T39A, S68G, T69X, K70X, K101R, D123E, I135T, S163I, I167V, D177E, I202V, R211K, I293V, P294T, E297K, K331R, M357T, I375V, T386I, V435I, E449D, D460N, L491S, K512T, L517I, S519N, I522V  
  MDRc3
clone: MDRc3 
D4T, 3TC, DDI, ABC EFV A62V, K70G, V75I, F77L, Y115F, F116Y, Q151M, M184V K103N, Y181C, G190A K20R, T39A, S68G, T69A, K101R, D123E, I135T, I167V, D177E, I202V, R211K, I293V, P294T, E297K, M357T, I375V, T386I, V435I, E449D, D460N, L491S, K512T  
  MDRc7
clone: MDRc7 
D4T, 3TC, DDI, ABC EFV A62V, V75I, F77L, Y115F, F116Y, Q151M, M184V K103N, Y181C, G190A T39A, S68G, T69X, K70X, K101R, D123E, I135T, S163I, I167V, D177E, I202V, R211K, I293V, P294T, E297K, K331R, M357T, I375V, T386I, V435I, E449D, D460N, L491S, K512T, L517I, S519N, I522V  
  36708-3 D4T, 3TC, DDI, ABC EFV A62V, V75I, F77L, Y115F, F116Y, Q151M, M184V K103N, Y181C, G190A K20R, T39A, S68G, T69X, K70X, K101R, D123E, I135T, S163I, I167V, D177E, T200A, I202V, R211K E194E*