<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Melikian (2012)
Title Standardized comparison of the relative impacts of HIV-1 reverse transcriptase (RT) mutations on nucleoside RT inhibitor susceptibility.
Citation AAC
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 1746
NumPts 1547
Subtype B, G, CRF02_AG, U, D, F, C, CRF01_AE, H


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Page 1   from Isolate 1 to Isolate 100 from Total 1746 Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
CA1144 CA9129 AZT, DDI, DDC, D4T, 3TC NVP D67N, K70R, M184V, T215F, K219Q V106A, G190A V35M, T69N, V118I, K122E, I135T, V179I, I202V, F214L, E248EK, S251SN V254VG 
CA1145 CA9912 D4T, DDI, AZT, 3TC NVP M41L, D67N, V75M, M184V, L210W, T215Y, K219Q K101PQ, K103KN T39A, E40F, K43E, V60I, K122E, D123E, I135T, I178M, V179I, Y181X, G196E, E203K, Q207D, H208Y, R211K, H221HY, L228H, A272P, T286A  
  CA8046 D4T, DDI, AZT, 3TC, ADV NVP, EFV M41L, D67N, V75M, M184V, L210W, T215Y, K219Q K101P, K103N T39A, E40F, K43E, V60I, K122E, D123E, I135T, I178M, V179I, G196E, E203K, Q207D, H208Y, R211K, L228H, A272P, T286A  
CA1158 CA2633 AZT, DDI, 3TC NVP M41L, V75L, M184V, L210W, T215Y  K43N, K122E, E138A, I142V, S162C, R172X, V179VA, I180X, T200X, R211Q, L228R L168LF 
CA1173 CA9916 AZT, DDI, 3TC, D4T None D67N, K70R, M184V, K219Q  T27S, I31V, K64H, T69N, K122E, I195L, D218E, L228H, V245M, E248V, K249Q, A288T, I293V  
CA1271 CA9915 AZT, DDI, D4T, 3TC NVP M41L, D67N, M184V, L210W, T215Y, K219N  K20R, T39A, E44D, V118I, K122E, I135T, D177E, H208Y, R211N, L283I, R284K, I293V, E297K, A304G  
CA1274 CA4372 AZT, DDC, 3TC, DDI, D4T DLV D67N, K70G, M184V, T215F, K219Q K103KN K102Q, K122E, I135V, D177E, G196E, I202V, E248ED, A272G, A288S, I293V  
CA1277 CA4391 AZT, D4T, DDI, DDC, 3TC None D67N, K70R, M184V, K219Q  V60I, K103R, K104KN, I135L, S162A, T200A, Q207E, F214L, D218DE, A272P, K277R, A288S  
CA1391 CA9918 AZT, ADV, 3TC, D4T, DDI None M184V  K102Q, K122E, D177E, I178M, V245E, A272P, K277R  
CA1413 CA3787 Unknown Unknown D67N, K70R  E28EK, V35I, R83K, T200A, E203K, Q207E, A272P, K277R, I293V  
CA1417 CA3798 AZT, 3TC, DDC NVP D67N, K70R, T215I, K219E V108I, Y181C K11R, E53D, K122E, H221HY, V245E  
CA1422 CA3808 AZT, DDI, DDC, D4T, 3TC NVP M184MV  E6ED, V35VM, V60VI, R83K, K122E, I135IV, K166R, T200I, A272PS, K277KR, I293V  
CA1433 CA3832 AZT, DDC, D4T, DDI None M41L, L74LV, M184V, L210W, T215Y  A98S, D121H, K122E, Q207E, R211K, K275KR  
CA1435 CA5025 AZT, D4T, 3TC, DDC, DDI, ABC EFV M41L, D67N, T69D, K70R, L74V, M184V, T215F, K219Q K101E, Y181C, G190S V35K, V60I, K104N, V118I, K122E, I135T, S162D, F214L, A272P  
CA1439 CA10989 AZT, D4T, NRTI, 3TC, DDI NVP M184V K103N K122E, I142V, R211K, Q269X, I293V  
CA1446 CA3861 AZT, 3TC, DDI, D4T NVP M41L, D67N, L74V, L210W, T215Y K103N, Y181C V35I, R83K, K122KE, E169D, R211K  
CA1449 CA3871 Unknown Unknown M41L, L74V, M184V, L210W, T215Y  K20R, T39A, K43KN, K122E, R211K  
CA1455 CA7736 AZT, DDI, D4T, DDC, ABC NVP, EFV M41L, D67G, K70R, L74V, T215Y, K219E K101E, Y181V, G190A E28A, V60I, S68G, K122E, I135T, I178M  
CA1486 CA4256 AZT, 3TC, D4T NVP M41L, V75M, M184V, L210W, T215Y A98AG, K103KN, Y181C, G190GR V35I, E44D, R83RK, K122E, I135IT, I142T, T165TA, I178L, G196DE, T200A, H208HY, R211K R199RIS, K201KQ, K219KI 
CA1523 CA4364 D4T, 3TC, DDI None F116Y, Q151M  S68G, K122E, D123E, S162C, R172K, D177E, T200A, R211S, F214L, D250DE, K277R, A288S  
CA1577 CA11722 DDC, AZT, 3TC, D4T EFV   V60I, R83K, K102Q, K277T, I293V, E297A, A304G  
CA1596 CA9099 AZT, 3TC, D4T, DDC, DDI, ABC NVP  Y181C T69N, D123E, I142V, I180V, G196E, T200A, E203K, L228LH, K277R, T286A, E297K  
CA1613 CA4582 Unknown, D4T, 3TC Unknown V75T, M184V  K11KR, S162C, T200A, E248V, A272P, T286A N265NT 
CA1823 CA10564 DDC, AZT, D4T, 3TC, DDI, Unknown Unknown D67N, T69D, K70R, M184V, T215F, K219Q  V118I, K122E, I135T, I180V, F214L, A272AP  
CA1827 CA4919 D4T, 3TC, AZT, DDI None M41L, D67N, L210W, T215Y  K20R, K43E, K122E, D123N, I178L, E203K, R211RK, V245M  
CA1836 CA12349 DDC, AZT, D4T, 3TC, DDI, ABC DLV M184V, K219KR  V35I, D123E, D177E, T200I, I202V, R211K, A272P, I293V  
CA2102 CA7756 AZT, D4T, DDI, 3TC EFV F77L, F116Y, Q151M  G196E, V245M, I293V N265NT 
CA2103 CA7758 AZT, DDI, DDC, D4T, 3TC None M41L, A62V, D67N, L74I, M184V, L210W, T215F, K219Q K103N V35L, K64KR, K122E, K173E, I178L, V179VI, D218E, L228H  
CA2197 CA7970 AZT, 3TC, D4T None A62V, T69S_SS, K70R, M184V  A98S, D123E, D177E, G196R, Q207E, R211K, V245K Q85QH 
CA2213 CA8018 AZT, 3TC, D4T NVP T215FI Y188L V118I, K122E, I135T, R211K, F214L, A272P, V276T, Q278QH, L283I K275KN 
CA2318 CA8413 DDC, AZT, 3TC, D4T, DDI None M41L, D67N, T69DN, L210W, T215Y  E44D, K64H, V75X, V118I, K122E, D123E, Q207E  
CA2320 CA8417 Unknown Unknown T69E_KS, V75M, L210W, T215F A98G, L100I, K103N K43Q, S48T, K82R, V118I, K122E, D123E, K166R, G196E, R211K  
CA3869 CA9044 Unknown Unknown T215D V108I, Y181C K102Q, D121Y, K122E, D177E, I178L, V245K  
CA3886 CA9078 AZT, 3TC None M184V K103N I135V, S162C, I178L, R211K, P243PH L234LH 
CA3894 CA9086 NRTI NNRTI K70R, Q151QL, M184V Y181YC K122KE, D123AE, K166KR, I202V, Q207AG, R211K, F214L  
CA3923 CA9128 Unknown, AZT, 3TC, DDC, DDI, D4T Unknown, NVP M41L, D67N, L210W, T215Y, K219N K103N, Y181C K11R, K20R, K43DE, E44A, V60I, V118I, D121Y, K122E, I135T, G196GE, T200I, R211K, A272P, K277R, I293V  
CA3933 CA12496 D4T, 3TC, AZT NVP, EFV M41L, D67N, L74V, M184V, L210W, T215Y L100I, K103N, K238KN P4S, T7A, K20R, V35M, K102R, E203K, Q207E, H208Y, R211K  
CA3946 CA9168 DDI, AZT, 3TC, DDC, D4T NVP M41L, D67N, T69D, K70KR, L210W, T215Y Y181I E44D, A98S, R211K, D218DE  
CA3948 CA9173 None None   K11KR, K20R, K32KN, V35I, R83K, A98S, K102KQ, K122E, I135T, E169ED, T200A, I202V, V245E, E248D, D250E  
CA4010 CA9268 Unknown Unknown   T39A, V111I, K122E, I135V, I142T, Q207E, F214L, L228R  
CA4011 CA12855 AZT, 3TC, D4T None T215TN, K219KE  I135T, S162A, I202V, P243AS, V245E, E248ED, D250E, R284K, A288S, I293V, E297A  
CA4014 CA10465 AZT, 3TC, DDI, D4T None M41L, M184V, L210W, T215Y  E44D, E53D, A98S, K122A, E169D, D177E, G196E, T200A, Q207E  
CA4075 CA9355 DDC, AZT, D4T, 3TC, DDI NVP M41L, D67N, T69D, L210W, T215Y  V21I, V35M, K43N, E44D, V106I, V118I, K122E, D123E, I135T, I178M, Q197I, H208Y, R211K  
CA4091 CA9379 AZT, 3TC, D4T, DDI NVP M41L, D67N, T215Y V106A, F227L V35M, R83K, D123E, S162A, Q207E, D237E, V245Q  
CA4092 CA12835 AZT, 3TC, Unknown Unknown K70R, M184V K103N, K238KT K122P, I135T, E169D, T200V, F214L, A272P, K277R, I293V, E297K  
CA4113 CA9418 AZT, 3TC, DDI, D4T None D67N, K70R, K219Q  K64N, A98S, D123E, T131TP, I135T, D177E, Q197E, Q207H, R211K, A272P, K277R, T286A, E297K  
CA4144 CA9896 AZT, DDI, 3TC, D4T NVP D67N, T215F, K219Q Y188L K122KE, I178L, R211K, F214L, K277R, T286A, A288G, E297K  
CA4172 CA9953 DDC, AZT, 3TC, D4T, DDI, Unknown Unknown M41ML, D67DN, M184MI, L210LW, T215SY, K219R  V35I, R83RK, K122KE, T165TI, I202V, R211RK, D250E, S251D, A272P, K277R, Q278N, L283I, T286A, I293V, P294S  
CA4307 CA10496 AZT, D4T, 3TC, DDI None   K122E, I178M, M230X  
CA4337 CA10532 D4T, 3TC, DDI NVP  K101E, G190A A98S, D123E, E138A, I142V, V179I, T200I, V245MT, A272P  
CA4357 CA10555 Unknown Unknown M41L, D67N, T69D, K70R, M184V, T215F  K122E, I135IV, I142V, G196E, V245MT, I293V  
CA4409 CA10617 AZT, DDI, 3TC, D4T, ABC NVP M41L, M184V, L210W, T215Y  E44D, K122E, D123E, I135T, S162Y, N175Y, T200E, R211K, L228LH  
CA4417 CA10626 AZT, 3TC, D4T NVP D67N, T69D, K70R, T215F, K219Q K103N, Y181C V35I, K122E, I135L, D177G, T200A, H208Y, R211K, D218E, A272P, L283I, I293V, E297R, R356K, K366R, A371V, I375V, A376T, T377A, A400T, A446S, L491LS, I506L  
CA4421 CA10630 AZT, 3TC, D4T, ABC, ADV NVP M41L, D67N, K70R, L74V, T215F, K219Q Y181C, G190A K20R, V60I, T69N, K122E, D123DN, I135T, G196E, H208Y, R211K, D218E, L228LH  
CA4472 CA10948 Unknown Unknown L74V Y181I E6D, V106I, I135IM, V179I, Q197K, T200I, F214L, H221Y, E248D  
CA4486 CA10967 AZT, D4T, 3TC, DDI NVP A62V, L74V, V75T Y181C K20R, S48T, K49R, V90I, D123E, S162DN, E169D, R211RK, K223KE, L228LR, V245K, A272P, K277R, L283I, I293V, P294Q, E297K  
CA4512 CA11001 Unknown Unknown M41L, D67N, L210W, T215Y A98G, K103N K43Q, K122E, I135V, Q174H, G196E, A272P, K277R, I293V  
CA4567 CA11193 Unknown Unknown M41L, D67N, L210W, T215Y, K219N V108I, Y181C E40F, K43E, V118I, K122E, D123E, R211K, A272P, T286A  
CA4578 CA11204 AZT, DDC, D4T, 3TC None M41L, D67DN, T69D, M184V, L210W, T215Y, K219R  V21I, V35I, E44D, R83K, K122E, T200A, E203K, H208Y, R211K, K223E, L228H, A272P, K281R, I293V, E297Q  
CA4725 CA11587 AZT, D4T, DDI, 3TC None M41L, D67N, T69D, M184V, L210W, T215Y A98G V35I, E44D, V60I, R83K, V118I, K122E, D123N, I135M, D177E, I178L, R211K, V245E, A272P, K277R, I293V, E297A L295LP, E300EV 
CA4770 CA11659 AZT, 3TC, D4T None M41L, D67DN, M184V, L210W, T215Y  K32KE, V118VI, D121X, K122E, I135V, K166R, D177E, R211K, V245M, A272P, K277R, I293V  
CA4787 CA11680 Unknown, AZT, DDI NVP, Unknown M41ML, T215F K103N, Y181C K122E, I135V, G196E, Q207A, V241M, V245Q  
CA4791 CA11685 AZT, 3TC None M184V  K20R, K122E, I142V, Q174H, T200AV, I202V, Q207E, L210LF, R211K, A272P G262G* 
CA4822 CA11732 AZT, D4T, 3TC, DDI NVP M41L, L74V, L210W, T215Y Y181I K20R, T39A, K122E, I135T, E138A, S162C, V179VI, E203K, R211K, H221HY, D250N  
CA4827 CA11742 AZT, 3TC, D4T, DDI None M41L, M184V, T215Y  S162C, E169D, T200A, R211K  
CA4867 CA11961 Unknown Unknown D67N, K70R, M184V, T215V, K219Q  E6D, V35M, T69N, A98S, T107A, D121H, K122E, I135IT, S162A, I167V, T200I, H208Y, A272P, E297K T286AG 
CA4873 CA11970 AZT, DDI, Unknown, 3TC Unknown D67N, T69D, K70R, M184V, T215F, K219Q K101E A98S, D123E, I135T, S162X, I195T, T200A, V245K, A272P, A288AS  
CA4876 CA11979 AZT, 3TC None M184V  E6D, I135T, S162C, Q207E, F214FL, K277R  
CA4997 CA12265 Unknown Unknown M184MV, T215F, K219KQ K103N K20R, S68SG, I135T, T200A, F214L, T240TA, V245K L168LF, M230MV, H235HQ 
CA5002 CA12270 AZT, 3TC, D4T, DDI None M41L, D67N, L210W, T215Y  K43Q, I50V, V60I, D123E, D177E, G196E, T200R, R211K, A272P, I293V  
CA5048 CA12326 D4T, 3TC None M184V  D121H, K122E, I135IT, I142IV, D177E, I178M, A272P  
CA5061 CA12341 Unknown Unknown M41L, T215FL  V60VI, A98S, K122E, I135V, E169D, G196E, T200A, K277R, T286TA, A288S, E297KR N136ND 
CA5140 CA12433 AZT, 3TC None M41L, M184V, L210W, T215Y  I135V, S162C, T200A, E203K, V292I K275K*, R284RS, L289LV 
CA5168 CA12464 RTI, Unknown RTI, Unknown M41L, D67N, T215Y  K43KE, A98S, V118I, I135V, S162C, T200A, Q207E, V245E, P247PA, S251I, I293V  
CA5195 CA12495 NRTI, DDC, D4T NVP M41L, D67N, L210W, T215Y, K219KR V106A, F227L K20R, V35IL, T39AS, E44D, V90I, V118I, K122E, E203K, Q207E, H208Y, R211K, K223E, K277R, Q278H, R284K, A288S, I293V  
CA5239 CA12831 AZT, 3TC, DDI, D4T None M184V  E6K, K122E, D123S, I135T, D177E, G196E, F214L, A272P, A288AG R72RG, N265ND 
CA5257 CA12853 AZT, 3TC, D4T, DDI, ABC NVP M41L, D67N, M184MV, L210W, T215Y  V35I, E44D, K122E, E169D, E203K, Q207E, R211K, K223E, T286A, I293V  
CA606 CA10474 AZT, DDI, D4T, 3TC None M41L, M184V, T215Y  K20R, A98S, K122E, A158S, Q197E, L228LH, V245EK  
CA622 CA10470 AZT, DDC, DDI, 3TC, D4T, ADV EFV M41L, D67N, K70R, L74I, L210W, K219E G190S V35I, E44D, L109LI, V118I, K122E, I202V, H208Y, R211K, T215X, T216X, L228H M230MV 
CA624 CA9919 DDI, D4T, 3TC, AZT None A62V, K70G, V75I, F77L, Y115F, F116Y, Q151M, M184V  S68G, T69K, K122E, K166R, D177E, R211K, K277R, I293V, E297K  
CA632 CA9435 AZT, DDC, DDI, D4T, 3TC None M41L, D67N, T69D, M184V, L210W, T215Y  T39A, K43A, E44D, V118I, K122E, I142V, Q207E, R211K, I293V, E297A  
CA637 CA9928 AZT, DDI, D4T, 3TC None M41L, M184V, T215Y  K20R, K122E, I135T, T200A, R211K, A272P, I293V, E297K  
CA640 CA9944 AZT, 3TC, D4T, DDI NVP M41L, M184V, L210W, T215Y  D123E, I135T, I142T, D177E, V179I, G196E, L228R  
CA790 CA10499 AZT, DDC, 3TC, D4T, DDI None M41L, D67N, K70R, T215Y, K219Q  V35I, T39A, K49KR, D123DE, I135T, V179I, D218E, E248D, I293V, E297A  
CA794 CA10469 AZT, DDI, DDC, D4T, 3TC NVP M41L, A62V, K65R, D67N, V75I, F116FY, Q151M, M184MV, L210W, T215Y  K20R, V21I, V35I, K43Q, E79D, R83K, K122E, Y181X, G196E, Q197K, F214FL, K223Q, A272P G112GS 
CA796 CA9945 AZT, DDI, D4T, 3TC, DDC NVP M41L, D67N, T69D, K70R, V75M, M184V, T215F, K219W K103KN, Y181C V35T, V60I, I94L, K122E, I135T, V179I, H208Y, D218E, L228H, V245E, E248Q, A272P, A288S, V292I, I293V  
CA799 CA9932 AZT, DDI, 3TC, DDC, D4T NVP M41L, A62AV, D67E, M184V, L210W, T215Y A98G, Y181IS V35M, K43KQ, E44D, S68G, K122E, I135T, D177E, V179I, G196E, E203K, Q207E, D250E, A272P, V276I, A288S, I293V, E297K  
SD-10 SD-10 NRTI, AZT, 3TC None M184V  K102Q, D123E, S162C, T200A, Q207E, A272P, K277R, I293V  
SD-13 SD-13 NRTI, D4T, 3TC None M41L, M184V, L210W, T215Y  K43Q, V60I, S68SG, T139M, R211K, V245Q, A272P, K277R, I293V, E297A  
SD-14 SD-14 NRTI, 3TC, DDI None M41L, L74I, M184V, L210W, T215Y  D177E, H208Y, R211K, L228R, T286A, T296S, E297EK  
SD-16 SD-16 NRTI, D4T, DDI None K70R  D177N, I178L, Q197E, R211K, V245T, D250E, T286A, I293V  
SD-18 SD-18 AZT, 3TC None D67N, K70R, M184V, K219Q  E6D, T27TS, V118I, K122E, I135T, S162Y, R211K, F214L, I293V  
SD-19 SD-19 NRTI, AZT, 3TC None M41L, M184V, T215Y  D123E, Q174K, T200A, R211K, V245VM, A272P, I293V, E297KR  
SD-2 SD-2 NRTI, AZT, 3TC None M41L, M184V, L210W, T215Y  T39DN, E40D, K43E, T69A, A98AS, V118VI, I135V, S162C, R211K, L228H, V245E, A272P, K277R, V292I K32K* 
SD-20 SD-20 NRTI, D4T, 3TC None M41L, M184V, T215Y  I135V, K166R, A272P, K277R, E297KR P140Q 
SD-21 SD-21 D4T EFV  K103N, P225H K122E, D123E, I135M, S162C, T200A, Q207A, R211K, V245Q, K277R, I293V  
SD-5 SD-5 NRTI, AZT, 3TC None M184V  K20R, K122E, I142V, T165I, K277R, A288S, I293V  
SD-6 SD-6 NRTI, D4T, 3TC None D67G, K70R, M184V, K219Q  K20R, S68G, K122E, Q207AE, R211K, T286A  
SD-7 SD-7 NRTI, 3TC, DDI None L74V, M184V  K122E, K173R, Q174K, I178M, Q207E, A272P, T286A  
WI004173 41731906 AZT, DDI, 3TC None M184V  E6D, K49KR, K122E, I135T, T200I, V245MT, I293V, E297K