<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Margot (2006)
Title Resistance development over 144 weeks in treatment-naive patients receiving tenofovir disoproxil fumarate or stavudine with lamivudine and efavirenz in Study 903
Citation HIV Med
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 124
NumPts 49
Subtype B, F, A, D


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Page 1   from Isolate 1 to Isolate 100 from Total 124 Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
7005 7005BL None None   S68G, I135T, T165I, R211K, V245K, T286A, V292I, E297R, L301I, V317A, S322SA, A327V, I341F, M357T  
  7005W48 D4T, 3TC EFV   S68G, I135T, T165I, T200TA, R211K, V245K, T286A, V292I, E297R, L301I, V317A, S322SA, A327V, I341F, M357T  
  7005W96 D4T, 3TC EFV M184MI  S68G, I135T, T165I, T200TA, R211K, V245K, A272AP, T286A, V292I, E297R, L301I, V317A, S322SA, A327V, I341F, M357T  
7006 7006BL None None   A98S, T200I, E203EQ, Q207X, R211RSNK, I257L, V261I, T286A, I293V, V317A, I326T, Q334L, T377L  
  7006W144 D4T, 3TC EFV   T27TA, A98S, K101KR, T200I, Q207AT, R211K, I257L, V261I, T286A, I293V, V317A, I326T, Q334L, T377L C280CY 
7025 7025BL None None   R83K, I159IV, T165TI, D250E, L283I, E297K, V317A, Q334G, F346Y, M357T, A360T, K390R, A400S  
  7025W48 D4T, 3TC EFV  K103N R83K, T165I, D250E, L283I, E297K, V317A, Q334G, F346Y, M357T, A360T, K390R, A400S  
7134 7134BL None None   D123N, S162C, T200I, R211K, V245K, T286A, K311R, I326V, K366R, T377Q, K390R  
  7134W48 D4T, 3TC EFV   D123N, S162C, T200I, R211K, V245K, T286A, K311R, I326V, K366R, T377Q, K390R  
7152 7152BL None None K70KR V179D V35L, K43S, I50V, R83K, D121H, E169D, D177E, E248D, R284K, T286A  
  7152W48 D4T, 3TC EFV K65R, K70R V106M, V179D L34LI, V35L, K43KSRN, I50V, R83K, D121HY, E169D, D177E, E248D, T286A, R358K, T369TA, E399G  
   D4T, 3TC EFV A62AV, M184V, N348NI V106M, V179D V35L, K43KSRN, I50V, R83K, D121HY, E169D, D177E, E248D, T286A, R358K, T369TA, E399G, A400AT  
  7152W96 D4T, 3TC EFV   V35L, K43S, K49KR, I50V, R83K, D121HY, E169D, I178L, E248D, R284K, T286A, R358K, K388KR, E399G  
7225 7225BL None None   D123E, K173E, D177E, I178M, T200A, E204K, Q207A, R211K, P243T, E297A, L301M, I326IV, G333D, Q334N, T377L, T386I, K390R  
  7225W48 D4T, 3TC EFV K65R L100I, K103N D123E, K173E, D177E, I178M, T200A, E204K, Q207A, R211K, P243T, E297A, L301M, I326IV, G333D, Q334N, T377L, T386I, K390R, I393IM  
   D4T, 3TC EFV K65R L100I, K103N V90VI, D123E, E169EK, K173E, D177E, I178M, T200A, E204K, Q207A, R211K, P243T, E297A, L301M, I326IV, G333D, Q334N, T377L, T386I, K390R, I393IM  
7227 7227BL None None   K64R, A98S, D123N, E138A, I142IT, R211Q, Q278H, T286A, P294S, E297K, K311KR, S322T, I329L, A355G, A376V  
  7227W48 D4T, 3TC EFV  K101E K64R, A98S, D123N, E138A, I142T, R211Q, Q278H, T286A, P294S, E297K, S322T, I329L, A355G, A376V  
7330 7330BL None None   E6ED, V8VI, K11KR, V35T, T39A, S48T, V60I, R83K, K166R, G196E, T200TPLI, Q207QE, L210LF, R211RK, D250DE, I293V, P294T, E297R, P345PQ, K366R  
  7330W48 D4T, 3TC EFV L74LV, M184MI G190S E6D, V35T, T39A, S48T, V60I, R83K, V90I, K166R, V179I, G196E, Q207E, L210F, R211K, D250E, I293V, P294T, E297R  
7377 7377BL None None   K20R, V35I, K122P, S162C, D177E, I178M, G196E, Q207K, R211A, L283I, T286A, V292I, I293V, Q334DN, T338S, R356RK, E370G, K390R  
  7377W144 D4T, 3TC EFV   K20R, V35VI, K122P, S162C, D177E, I178M, G196E, Q207QEK, R211AE, L283I, T286A, V292I, I293V, Q334DN, T338S, E370G, Q373QH, K390R  
7401 7401BL None None   A98S, D123E, I180V, T200TAEK, R211RK, I293V, E300EQ, K390R  
  7401W48 D4T, 3TC EFV M184V  A98S, D123E, I180V, T200TAEK, R211RK, I293V, E300Q, K390R  
   D4T, 3TC EFV   A98S, D123E, I180V, T200TA, R211K, I293V, E300Q, K390R  
  7401W96 D4T, 3TC EFV   A98S, D123E, I180V, T200AE, R211K, T286TA, I293V, E300Q, K390R  
7451 7451BL None None   D86E, A158S, L210LS, R211RK, A327V, M357T, K390R  
  7451W48 D4T, 3TC EFV M184V, N348NI K103N D86E, K102KQ, A158S, I202IV, R211RK, A327V, M357T, K390R  
7626 7626BL None None   V35I, K82R, R83K, D123E, I180V, T200A, K281KR, T286A, I293IV, E297K, G333D, K390R  
  7626W48 D4T, 3TC EFV   K82R, R83K, D123E, I180IV, T200A, K281KR, T286A, E297K, G333D, K390KR  
7630 7630BL None None   E6D, K20R, I178M, T286A, E297A, I329IV, Q334L, M357V, A360T  
  7630W48 D4T, 3TC EFV M184V, N348NI K103N E6D, K20R, K122KE, I178M, T286A, E297A, D324DE, I329IV, Q334L, M357V, A360T, T369TI, E399EG  
  7630W96 D4T, 3TC EFV M184V, N348NI K103N E6D, K20R, I178M, T286A, E297A, D324E, I329V, Q334L, M357V, A360T, T369TI, S379SC, E399EG  
  7630W144 D4T, 3TC EFV M184V, N348NI K103N E6D, K20R, I178M, T200TA, T286A, E297A, D324E, I329V, G333GE, Q334L, M357V, A360T, T369TI, S379SC, E399EG, A400AT  
7655 7655BL None None   V10VA, V35I, D123E, I135V, D177E, Q207E, P294S, V317A, Q334L, R356K  
  7655W48 D4T, 3TC EFV  K103N, V106M V35I, D123E, I135V, D177E, R206K, Q207E, P294S, E297K, V317A, G333E, Q334L, R356K, K390R  
7658 7658BL None None   S68G, K122I, K166R, R211Q, V241I, E297A, L301I, I329L, V365I, A376S, V381I, K390R  
  7658W96 D4T, 3TC EFV M184V  S68G, T69TI, K122I, I142V, K166R, R211Q, V241I, E297A, L301I, I329L, V365I, A376S, V381I, K390R, E396EK G285GR, I293IM 
  7658W144 D4T, 3TC EFV M184V, N348I K103N S68G, K122I, I142V, K166R, I202IV, R211Q, V241MI, E297A, L301I, I329L, V365I, A376S, V381I, K390R  
7665 7665BL None None   K122KE, I135IV, S162C, T200TA, Q207E, R211K, V245VATM, T286A, D324DE, M357T, K390R, Q394N, A400S  
  7665W144 D4T, 3TC EFV   E40ED, I135IV, S162C, T200A, Q207E, R211K, V245VE, E248ED, T286A, D324E, M357T, K390R, Q394N, A400S  
7672 7672BL None None   V35E, T39TA, R83RK, I135R, I178IL, V189I, I202V, E204K, Q207E, T286A, E297K, L301M, K311R, V317VA, D324DE, Q334E, K366R, K390R  
  7672W48 D4T, 3TC EFV   V35E, T39TA, R83RK, I135R, V189I, I202V, E204K, Q207E, L228LP, T286A, E297K, L301M, K311R, V317VA, D324DE, Q334E, K366R, K390R  
7680 7680BL None None   V35T, V60I, R83K, Q197E, Q207E, R211RK, A272S, Q278N, T286A, E297K, K385R, K390R  
  7680W96 D4T, 3TC EFV  K103N V35T, V60I, R83K, Q197E, Q207E, R211RK, A272S, Q278N, T286A, E297K, K385R, K390R  
  7680W144 D4T, 3TC EFV L74LV L100LI, K103N, P225PH V35T, V60I, R83K, Q197E, Q207QE, A272S, Q278N, T286A, E297K, K385R, K390R  
7751 7751BL None None   V35VI, D123E, K173E, T200A, Q207E, V245K, K249KQ, I326V, G335N, M357T, S379G, K385R, K390R  
  7751W48 D4T, 3TC EFV M184V, N348NI K103N K20KR, D123E, K173E, Q197R, T200A, Q207E, V245K, I326V, G335SN, M357T, R358RK, S379G, K385R, K390R  
7754 7754BL None None   E6EK, K11KR, V106I, A158S, I178M, T200TI, E203EK, V245K, I293V, E297A, E300Q, I326V, R358K, T386I  
  7754W48 D4T, 3TC EFV   V106I, A158S, I178M, V245K, I293V, E297A, E300Q, I326V, R358K  
7755 7755BL None None   V90VI, D123E, I142IT, S162C, G196E, I202V, R211RK, K281R, L283LI, I293V, T296S, I326V, A360AT  
  7755W96 D4T, 3TC EFV   V90VI, D123DE, I142T, S162SC, G196E, I202V, K281R, L283LI, I293V, T296S, I326V, A360AT  
  7755W144 D4T, 3TC EFV   V90I, D123E, I142T, S162C, G196E, I202V, K281R, L283LI, I293V, T296S, I326V, A360AT  
7801 7801BL None None   D123E, I135T, K166R, V245K, T286V, I293V, E297R, I329L, R358K, K366KR, T386I  
  7801W144 D4T, 3TC EFV   D123E, I135T, K166R, R211RQ, V245K, T286V, I293V, E297R, I329L, R358K, T386I  
7827 7827BL None None  V179D V118I, T200A, Q207E, T286A, I293V, T338S, K366R, K390R  
  7827W48 D4T, 3TC EFV M184V V106M, V179D K20R, K103KR, V118I, I135M, T200A, Q207E, V245I, T286A, I293V, T338S, H361HP, K366R, K390R, A400AT  
  7827W96 D4T, 3TC EFV  V106M, V179D V118VI, T200A, Q207E, T286A, I293V, T338S, K366R, K390R  
8125 8125BL None None   E28A, K32Q, V35I, R83K, D123E, I135T, T286A, E297K, G359S  
  8125W48 D4T, 3TC EFV   E28A, K32Q, V35I, R83K, D123E, I135T, T286A, E297K, G359S  
8131 8131BL None None   V35M, T39I, D123E, I132IV, R211K, V276VI, K277KR, R284K, T286A, T296S, E297K, D324E, I326V, I329L, M357V  
  8131W96 D4T, 3TC EFV   V35M, E36EK, T39I, G45GE, D123E, I135IVM, R211K, A272AS, V276VI, K277KR, R284K, T286A, T296S, E297K, D324E, I326V, I329L, M357V R72RK 
  8131W144 D4T, 3TC EFV   V35M, T39I, D123E, I135ITM, R211K, A272S, R284K, T286A, T296S, E297K, D324E, I326V, I329L, M357V  
8155 8155BL None None   E6D, V35L, K122KE, D123DE, D177E, I178M, T200LI, R211K, V245T, R284K, T286A, I293V, I375V, T377Q, S379C, K390R V60VMI 
  8155W96 D4T, 3TC EFV  G190GA E6D, V35L, D123DE, D177E, I178M, T200L, R211K, V245T, D250DE, I274IV, R284K, T286A, I293V, I375V, T377LQ, S379C, K390R  
8158 8158BL None None   E6D, W88C, K104R, S162A, D177E, E203ED, Q207X, R211X, L283LI, I293V, E300Q, S322T, D324DE, I329L, R356RK, T377TMI, A400S  
  8158W96 D4T, 3TC EFV   E6D, W88C, K104R, K122KE, S162A, D177E, E203ED, Q207X, R211X, I293V, E300Q, S322T, I329L, V381VI, A400S  
  8158W144 D4T, 3TC EFV M184V K101E, K103N E6D, W88C, K104R, S162A, D177E, E203ED, Q207AETK, R211RGAT, I293V, E300Q, S322T, D324DE, I329L, V381I, E399G, A400S  
8159 8159BL None None   K11KR, K20R, D123E, I180V, E194D, Q197K, T200E, R211K, L283I, P294T, E297K, I329IL, G333GE, Q334QL, M357I, R358K, T369TSA, E370ED, Q373QH, K374KR, I375IV, K390R, E399D  
  8159W96 D4T, 3TC EFV M184V K103N K11KR, K20R, K101KQ, D123E, I180V, E194D, Q197K, T200E, R211K, L283I, P294T, E297K, I329L, G333GE, Q334QL, M357I, R358K, T369V, K374R, K390R, K395KR, E399D  
8258 8258BL None None   K11TA, K20R, V35T, T39A, E40ED, D123DN, I135V, K173S, D177G, V179I, I202V, Q207A, R211S, V245Q, E248N, K281R, T286A, K287KR, A288S, E291D, V292I, I293V, P294T, E312D, G335D, M357KT, G359S, T369A, A371V, V372VIM, I375V, A376V, T377L  
  8258W144 D4T, 3TC EFV   K11A, K20R, V35T, T39S, I135V, K173S, D177G, V179I, I202V, Q207A, R211S, V245Q, E248N, K281R, T286A, K287R, A288S, E291D, V292I, I293V, P294T, E312D, G335D, M357K, G359S, T369A, A371V, V372I, I375V, A376V, T377L  
8325 8325BL None None   V35T, V60I, K101KR, D121Y, I135V, I142IT, D177E, I178L, Q207D, R211K, P243T, V245Q, E248D, D250E, A272S, R284K, T286A, I293V, E297N, I329LV, F346FC, A360T, A376S, T386I, K390R  
  8325W144 D4T, 3TC EFV   V35T, V60I, D121Y, I135V, D177E, I178L, Q207D, R211K, P243T, V245Q, E248D, D250E, A272S, R284K, T286A, I293V, E297N, S322SL, I329L, A360T, A376S, T386I, K390R  
8475 8475BL None None   K20R, D123E, I135T, D177E, V245M, I293V, E297EK, V317A, Q334L, A360T, T377TI, V381VI  
9183 9183BL None None  V179VD K11KN, V35T, K49R, D123DN, I135V, S162C, E169ED, K173A, Q174K, D177DE, Q197QE, Q207E, R211K, V245Q, E248DN, T286A, E291D, V292I, I293V, E297A, R307K, F346L, R356K, G359S, T369A, T377L, K390KR, Q394L, E399D  
  9183W48 D4T, 3TC EFV  V179D K11KN, V35T, K49R, V106VI, I135V, S162C, E169D, K173A, Q174K, Q197E, Q207E, R211K, V245Q, E248D, T286A, E291D, V292I, I293V, E297A, R307K, F346L, R356K, G359S, T369A, T377L, K390R, Q394L, E399D K13KR 
9184 9184BL None None   V35T, E40D, V60I, D123DN, I135L, S162H, E169D, K173A, Q174K, D177N, T200A, Q207E, R211K, V245Q, E248D, S251I, K281R, T286A, I293V, E297RK, Q334L, I341L, A371V, T377L, K390R, Q394L  
  9184W48 D4T, 3TC EFV   V35T, E40ED, V60I, D123DN, I135L, I142IV, S162H, E169D, K173A, Q174K, D177N, T200A, Q207E, R211K, P243PS, V245Q, E248D, S251I, K281R, T286A, I293V, E297R, Q334L, I341LF, K366KR, A371V, T377L, K390R, Q394L  
  9184W96 D4T, 3TC EFV   V35T, E40ED, V60I, I135L, I142IV, S162H, E169D, K173A, Q174K, D177N, T200A, Q207E, R211K, V245Q, E248D, S251I, K281R, T286A, I293V, E297RK, Q334X, I341LF, A371V, T377L, V381VI, K390R, Q394L  
  9184W144 D4T, 3TC EFV   V35T, T39TA, V60I, I135L, I142IV, S162H, E169D, K173A, Q174K, D177N, T200A, Q207E, R211K, V245Q, E248D, S251I, K281R, T286A, I293V, E297R, Q334X, I341F, A371V, T377L, V381I, K390R, Q394L  
9304 9304BL None None   V35VI, K102Q, V118VI, D123E, I135T, S162C, F171Y, D177E, T200A, V245VM, I293V, T386I  
  9304W48 D4T, 3TC EFV   V35VI, T39TA, K102Q, K122KGER, D123E, I135T, S162C, F171Y, D177E, I178IV, T200A, V245M, I293V, T386I  
9411 9411BL None None   I135T, Q174H, R211RK, V245I, E248D, I293V, E297A, D324E, G333E, M357I, T386I, K390R  
  9411W96 D4T, 3TC EFV   I135T, F171FY, Q174H, Q207QR, R211RK, V245I, E248D, I293V, E297A, D324E, G333E, M357I, T386I, K390R  
  9411W144 D4T, 3TC EFV   I135T, Q174H, Q207R, R211K, V245I, E248D, I293V, E297A, D324E, G333E, M357I, T386I, K390R  
9418 9418BL None None   R83K, D123E, D177DE, I178M, G196E, R211RG, K281R, T286TA, I293V, E297K, D324DE, Q334Y, A360T, V365VI  
  9418W48 D4T, 3TC EFV   R83K, D123E, I178M, G196E, E204EK, R211RG, K281R, T286A, I293IV, E297K, D324DE, Q334W, A360T, V365VI, A376AT, A400AT  
9429 9429BL None None   K11KE, D123E, I135T, T200I, V245I, E248D, A272S, A288S, I293V, E297A, Q334L, F346FY, R358K, K366R, T386I, K390R  
  9429W48 D4T, 3TC EFV   D123E, I135T, T200I, V245I, E248D, A272S, A288S, I293V, E297A, Q334L, F346Y, R358K, K366R, T386I, K390R  
   D4T, 3TC EFV  K103N D123E, I135T, T200I, V245I, E248D, A272S, A288S, I293V, E297A, Q334L, F346Y, R358K, K366R, T386I, K390R  
  9429W96 D4T, 3TC EFV  K103N, P225H D123E, I135T, T200I, V245I, E248D, A272S, A288S, I293V, E297A, Q334L, F346Y, R358K, K366R, T386TI, K390R  
  9429W144 D4T, 3TC EFV  K103N, P225H K101KQ, K102KR, D123E, I135T, T200I, V245I, E248D, A272S, A288S, I293V, E297A, Q334L, F346FY, R358K, K366R, T386I, K390R  
9466 9466BL None None   I135T, S162A, Q207E, R211K, W212WG, V245M, V276I, L283I, I293V, E297K, Q334E, T386I  
  9466W144 D4T, 3TC EFV  K103KN K101KQ, I135T, S162A, Q207E, R211K, V245M, V276I, L283I, I293V, E297K, Q334E, T386I  
9658 9658BL None None   V35T, T39TI, V60I, D123E, I135IV, T139TA, Q197QK, I202IV, K281R, T286A, E297K, V317A, R356RK, K366R, K374KR, Q394L, E399D  
  9658W48 D4T, 3TC EFV M184I K103N, M230ML, K238KT V35T, V60VI, K101KQ, D123E, I135IV, T139TA, I142IV, Q197K, I202V, K281R, T286A, E297K, V317A, A360AT, K366R, K374KR, T386TA, Q394L, E399D  
  9658W96 D4T, 3TC EFV  K103N, K238T V35T, K101Q, D123E, Q197K, I202V, K281R, T286A, E297K, V317A, K366R, T386A, Q394L, E399D  
9667 9667BL None None   I135L, E138A, S162A, I167V, V245Q, P294T, I329L, Q334E, Y339F, R356K, T369TA, I375IV, T377I, K388R  
  9667W144 D4T, 3TC EFV   I135L, E138A, S162A, I167V, V245Q, P294T, I329L, Q334E, Y339F, R356K, T369A, K374KR, I375V, T377I, K388R