Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Barber (2012)
Title Frequency and patterns of protease gene resistance mutations in HIV-infected patients treated with lopinavir/ritonavir as their first protease inhibitor.
Citation J Antimicrob Chemother
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 31
NumPts 31
Subtype B, C, CRF02_AG, D, A, CRF35_AD, CRF05_DF, CRF45_cpx, CRF01_AE, G, CRF49_cpx


Clinical PR Isolates

2204 2204 LPV  M46MI, I54V, V82AS L10FV K14KR, I15V, E35ED, M36MI, R41K, L63P, A71V, T91TS  
2726 2726 LPV  M46MI  Q2QH, N37S, I64V, K70RT, V77I L63KM 
33245 33245 LPV   Q58E T12S, L19I, M36I, R41K, D60E, L63A, H69K, L89M, I93L  
33960 33960 LPV  I54V, V82A  L10I, T12N, K14R, I15V, G16E, K20R, M36I, N37D, R41K, D60N, Q61D, I66V, C67E, H69K, A71AV, I72R, L89M, I93L  
40174 40174 LPV    K14KR, I15IV, L19I, R41K, R57RK, I64V, E65D, I85V  
42185 42185 LPV    W6WL, G16E, L19LI, R41K, I62IV, L63LH, H69HKNQ, I85IV  
42704 42704 LPV  L90LM  L10I, K43R, R57K, L63P, C67S, I93L  
47235 47235 LPV  L76V  T12S, I15V, L19I, M36I, R41K, L63P, H69K, L89M, I93L  
48702 48702 LPV  I54IV  I13V, I15L, L19I, K20I, M36I, N37S, R41K, H69K, L89M  
48826 48826 LPV  V32I, M46I, I47A L10F, L33I, L89V I13V, K20R, E35D, M36I, R41K, R57K, I62V, H69K, K70R, T74S  
50489 50489 LPV   F53L K20R, E35D, M36I, N37D, I62V, L63P, E65D, A71T, V77I, I93L  
50857 50857 LPV  M46I, L76V, I84V  L10I, I13V, G16E, M36I, R41K, L63T, H69K, L89M  
50940 50940 LPV   Q58E I13V, R41K, R57K, Q61N, H69Y, V77I  
51030 51030 LPV  I54V  T12S, I15V, L19I, E35D, M36I, R41K, R57K, H69K, V82I, L89M, I93L  
54453 54453 LPV  I84V  Q7R, I15V, E35D, N37S, L63P  
56069 56069 LPV  M46I, I54V, L76V, V82C  L10V, I13V, K14R, L63P, I64V  
56144 56144 LPV  I47V  I15V, R41K, L63S, H69K, I93L  
56572 56572 LPV  V82A L10F I15V, G17D, L19I, M36I, D60E, L63P, H69K, L89M, I93L  
60412 60412 LPV   L33LF I15V, R41K, I62V, L63P, I64V, C67S  
60783 60783 LPV  M46I, I84V  L10I, I13V, G16E, Q18QK, L19LP, K20I, E35D, M36I, N37T, P39S, R41K, I62V, H69K, K70R, T74A, L89M  
60784 60784 LPV  V32VI, M46MI, I47IATV, I54IV, V82VA  L10I, M36I, R41K, I62V, I64V, H69Y, A71T, I93L  
65886 65886 LPV  I54IV  E35D, M36I, N37D, Q61QR, L63P, V82VI, I93L  
65994 65994 LPV  M46MI, I54V, V82A  L10I, T12S, I15V, L19V, M36I, R41K, K45KR, L63P, H69K, T74S, I93L  
66051 66051 LPV  I54V, V82A  I13V, K14R, K20I, M36I, R41K, I64L, H69K, K70R, L89M  
66452 66452 LPV  M46IL F53FL I62V, L63H, A71V, V77I, I93L  
67784 67784 LPV  I54V  I13V, G17D, K20R, E35D, M36I, R41K, R57K, D60E, I62V, L63I, H69K, L89M  
68061 68061 LPV  I54V, L90LM  I13V, K14R, K20I, E35Q, M36I, N37NDEK, R41K, I62IV, L63P, C67E, H69K, A71AV, V82I, L89M, I93IM  
69576 69576 LPV  I54V, V82A L10F T12S, I15V, L19I, M36I, R41K, L63T, H69K, L89M, I93L  
76142 76142 LPV   Q58E T12A, I13V, K14R, L33V, N37T, R41K, I62V, L63P, I64V, Q92E  
77406 77406 LPV  M46I L10F, T74TP I13V, I15IV, E35D, M36I, R41K, L63C, H69K, N83S, L89M  
9709 9709 LPV  M46MI  Q18M, L63P