<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Sigaloff (2011)
Title Accumulation of HIV drug resistance mutations in patients failing first-line antiretroviral treatment in South Africa.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 69
NumPts 43
Subtype C, K

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
GP00022848 GP00022848_1 D4T, 3TC EFV M184V K103N, P225H V35T, T39E, S48T, V60I, K122E, D123S, I135L, E138Q, K173A, Q174K, T200A, Q207A, R211K, V245Q, A272P, E291D, V292I, I293V  
  GP00022848_2 D4T, 3TC EFV M184V K103N, P225H P14PT, G18GA, V35T, T39E, S48T, V60I, K122E, D123S, I135L, E138Q, K173A, Q174K, T200A, Q207A, R211K, V245Q, A272P, E291D, V292I, I293V M16MK, D17DY 
GP25335969 GP25335969_1 AZT, 3TC EFV D67N, K70R, M184V, T215F, K219E V106M, V108I, F227L K20R, V35T, E36A, T39E, S48T, E53D, V60I, K122E, D123G, A158S, K173A, D177E, T200A, Q207E, R211K, K223T, L228R, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
  GP25335969_2 AZT, 3TC EFV D67N, K70R, M184V, T215F, K219E V106M, V108I, F227L K20R, V35T, E36A, T39E, S48T, E53D, V60I, K122E, D123G, A158S, K173A, D177E, T200A, Q207E, R211K, K223T, L228R, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
GP25416072 GP25416072_1 D4T, 3TC EFV   V35T, T39E, D121DH, K122E, D123S, I135T, E138A, S162C, K173A, D177E, T200A, Q207AV, R211K, V245Q, A272P, T286A, E291D, V292I, I293V E36L 
  GP25416072_2 D4T, 3TC EFV L74LI, M184V K103N, P225H V35T, T39E, K102Q, K122E, D123S, I135R, S162C, K173T, D177E, T200A, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
GT00011000 GT00011000_1 D4T, 3TC EFV M41ML, M184V, T215Y K103N V35T, T39AE, E42EK, S48T, V60I, D76X, K101Q, K122E, D123S, I135L, E138A, K173A, I178L, T200A, Q207K, R211K, V245Q, A272P, E291D, I293V, E308X R172RM, S191Y 
  GT00011000_2 D4T, 3TC EFV D67N, M184V, K219Q K103N, Y318F V35T, T39E, S48T, V60I, K122E, D123S, I135L, E138A, K173A, I178L, T200A, Q207T, R211K, V245Q, I257IL, A272P, T286A, E291D, I293V, L295I, E308D I309~ 
GT00057847 GT00057847_1 AZT, 3TC EFV A62V, M184V K101E, G190V V35T, E36A, T39E, S48T, T58S, V90I, K122E, D123S, I135IT, N147NK, K173A, Q174K, D177E, T200A, E203G, Q207E, R211K, V245Q, K277R, T286A, E291D, V292I, I293V, E297K  
  GT00057847_2 AZT, 3TC EFV A62V, M184V K101E, G190V V35T, E36A, T39E, S48T, T58S, V90I, K122E, D123S, N147K, K173A, Q174K, D177E, T200A, E203G, Q207E, R211K, V245Q, K277R, T286A, E291D, V292I, I293V, E297K  
GT00077455 GT00077455_1 Unknown Unknown M184V K103N, M230L V35T, T39E, K82R, K122E, D123S, K173A, D177E, Q197QH, T200A, Q207E, R211K, P243H, V245Q, A272S, K277R, T286TA, E291D, V292I, I293V, Q334N, G335E, T338S, R356K, M357R, G359T, A371V, I375V, T377L, V381I, K390R, A400T  
  GT00077455_2 Unknown Unknown M41ML, L74LI, M184V, T215FY K103N, G190A V35T, E36A, T39E, S48T, K122E, D123S, K173A, D177E, T200A, Q207R, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, L295LM, E328K, Q330R I329Y, K331A, Q332E 
GT00135141 GT00135141_1 D4T, 3TC EFV D67N, K70KR, M184V K103N, V106M V35T, T39E, S48T, K122E, D123S, I135T, T139R, I142T, T165I, K173A, Q174K, T200A, Q207A, F214FL, V245Q, A272P, K277R, E291D, V292I, I293V, E297Q  
  GT00135141_2 D4T, 3TC EFV D67N, K70KR, M184V K103N, V106M V35T, T39E, S48T, K122E, D123S, I135T, T139R, I142T, T165I, K173A, Q174K, T200A, Q207A, F214FL, V245Q, A272P, K277R, E291D, V292I, I293V, E297Q  
GT00150239 GT00150239 D4T, 3TC NVP V75I, M184V V106M, F227L K32R, V35T, E36A, T39E, S48T, V60I, K122E, I132L, T139A, K173A, D177E, E203EK, Q207E, R211K, K223KE, V245Q, E248D, D250E, A272P, K275Q, K277R, T286A, E291D, V292I, I293V  
GT00162100 GT00162100_1 AZT, 3TC EFV M41ML, D67N, M184V, L210W, T215Y, K219KQ V106M, V179D, M230L V35T, T39E, S48T, K103X, K122E, D123G, K166R, K173A, Q174H, D177E, G196T, T200A, I202V, Q207G, R211K, V245Q, E248D, A272P, K277R, K281X, T286P, A288T, E291D, V292M, P294X, L295X, E300Q, L301I, N306X, E308G K73E, T84P, K287S, L289~, I293Y, A299~, E302R 
  GT00162100_2 AZT, 3TC EFV M41ML, D67N, M184V, L210W, T215Y, K219KQ V106M, V179D, M230L V35T, T39E, S48T, K103X, K122E, D123G, K166R, K173A, Q174H, D177E, G196T, T200A, I202V, Q207G, R211K, V245Q, E248D, A272P, K277R, K281X, T286P, A288T, E291D, V292M, P294X, L295X, E300Q, L301I, N306X, E308G K73E, T84P, K287S, L289~, I293Y, A299~, E302R 
GT00170194 GT00170194_1 D4T, 3TC EFV  G190GA V21VI, V35T, E36A, T39E, S48T, V60I, K122E, D123S, K173A, Q174QK, D177E, Q197K, T200E, Q207EK, R211RK, V245Q, A272S P4PA 
  GT00170194_2 D4T, 3TC EFV  G190GA V21VI, V35T, E36A, T39E, S48T, V60I, K122E, D123S, K173A, Q174QK, D177E, Q197K, T200E, Q207EK, R211RK, V245Q, A272S, T286A, E291D, V292I, I293V, E305D P4PA 
GT00173303 GT00173303 D4T, 3TC EFV M184V K103N E36A, T39E, S48T, K122E, D123N, T139K, K173T, Q174N, D177E, I178M, T200A, I202V, Q207I, R211K, V245Q, A272P, K277R, L283I, I293V, P294T  
GT00201512 GT00201512_1 D4T, 3TC EFV T215Y  P4PH, V35T, T39E, S48T, K122E, D123DGNS, S162C, K166KR, K173A, D177E, T200A, Q207E, R211K, D218E, L228LR, V245Q, A272P, T286A, E291D, V292I, I293V  
  GT00201512_2 D4T, 3TC EFV M184V K103N, V108I P4H, V35T, T39E, S48T, K122E, D123S, S162C, K166R, K173A, D177E, T200A, Q207E, R211K, D218E, V245Q, A272P, C280*, T286A, E291D, V292I, I293V  
GT00216110 GT00216110 AZT, 3TC EFV M184V K103N, P225PH E28A, V35T, T39E, S48T, K122E, D123G, I135T, K173S, D177E, T200A, I202V, E204Q, Q207E, V245Q, K277R, Q278E, T286A, E291D, V292I, I293V, R307K G231GR 
GT00235354 GT00235354 D4T, 3TC EFV  K103N V21VI, V35T, E36A, T39E, S48T, E79K, L100X, D121Y, K122E, I159IV, T165TI, K173T, Q174K, D177E, I178IM, T200A, Q207E, R211K, V245Q, A272P, K277KR, T286A, E291D, V292I, I293V, R307RK, V317A  
GT00240772 GT00240772_1 AZT, 3TC EFV D67N, K70R, M184V, T215F, K219E L100I, K103N V35T, T39E, S48T, T69N, V90I, K122E, D123G, T139K, K173A, D177E, T200A, E204Q, R211K, L228R, V245Q, A272P, K281R, E291D, I293V, V317X  
  GT00240772_2 AZT, 3TC EFV D67N, K70R, M184V, T215F, K219E L100I, K103N V35T, T39E, S48T, T69N, V90I, K122E, D123G, T139K, K173A, D177E, T200A, E204Q, R211K, L228R, V245Q, A272P, K281R, E291D, I293V  
GT00251488 GT00251488 AZT, 3TC EFV M184V, T215Y Y188L V35T, E36A, T39E, K102W, K122E, D123G, K173A, Q174K, N175NY, D177E, T200A, Q207E, R211K, D218E, V245Q, A272P, K277R, T286A, E291D, V292I, E297D  
GT00256420 GT00256420 D4T, 3TC EFV D67N, K70R, M184V Y188C, M230L V35T, T39E, S48E, V106L, D123E, T139R, S162A, E169R, K173E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E297D  
GT00258683 GT00258683_1 D4T, 3TC EFV  K103N V35T, E36A, T39E, S48T, S162A, K173T, Q174K, D177DE, I178IM, Q207E, R211K, P243T, V245Q, A272P, K275R, Q278H, T286A, E291D, V292I, I293V, P294T  
  GT00258683_2 D4T, 3TC EFV  K103N V35T, E36A, T39E, S48T, S162A, K173T, Q174K, D177E, I178M, Q207E, R211K, P243T, V245Q, A272P, K275R, Q278H, T286A, E291D, V292I, I293V, P294T  
GT00267785 GT00267785_1 Unknown Unknown T215D  V35T, T39G, R83X, Q91X, G93X, G99X, L100X, K122E, T131P, E138X, I142V, K173A, Q174K, T200A, Q207R, R211K, V245Q, A272P, K277R, I293V, V317A A98Q 
  GT00267785_2 Unknown Unknown T215AD  V35T, T39EG, E40ED, K122E, D123DN, I142IV, K173A, Q174K, T200A, Q207RT, R211K, F214FL, V245Q, A272P, K277R, I293V, V317A Q91H 
GT00273391 GT00273391_1 Unknown Unknown M184V K103N V35T, E36A, T39E, S48T, V60I, K122E, D123N, I135L, K173V, Q174K, D177E, T200A, Q207A, R211K, L228Q, E248D, D250G, A272P, Q278X, V292I, I293V  
  GT00273391_2 Unknown Unknown  K103N E6ED, V35T, E36A, T39E, S48T, V60I, K122E, D123N, K173V, Q174K, D177E, T200AE, Q207A, R211K, V245VL, E248DN, D250DG, A272P, E291D, V292I, I293V  
GT00289340 GT00289340_1 D4T, 3TC EFV K70KR, M184V K103N, P225PH K20KR, V35T, T39EK, S48E, V60I, K122E, I135IL, K173A, Q174KR, D177E, I178L, G196E, T200A, E204Q, Q207E, R211RK, F214L, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V  
  GT00289340_2 D4T, 3TC EFV K70KR, M184V K103N, P225PH K20KR, V35T, T39EK, S48E, V60I, K122E, I135IL, K173A, Q174KR, D177E, I178L, G196E, T200A, E204Q, Q207E, R211RK, F214L, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V  
GT0029819 GT0029819_1 None None V75I, M184V, T215TFIS K103N, V108VI I31IL, V35T, T39EK, S48T, E53D, V60VI, V90VI, K122E, D123S, I132L, K173T, Q174R, I178L, T200A, Q207E, R211K, F214FL, H221HY, V245Q, V254I, A272P, T286A, E291D, V292I  
  GT0029819_2 None None V75I, M184V, T215TFIS K103N, V108VI I31IL, V35T, T39EK, S48T, E53D, V60VI, V90VI, K122E, D123S, I132L, K173T, Q174R, I178L, T200A, Q207E, R211K, F214FL, H221HY, V245Q, V254I, A272P, T286A, E291D, V292I  
GT00303225 GT00303225 D4T, 3TC EFV M41L, L74I, V75S, M184V, L210W, T215Y K101E, V108I, Y181C, G190A K20R, V35T, K49R, T58N, S68SG, K103R, V118VI, K122E, D123S, T139V, S162D, K173T, Q174K, D177E, I178M, T200A, E203ED, Q207E, R211K, H221Y, V245K, S251D, A272P, K277R, A288S, I293V, E297A  
GT00308796 GT00308796_1 TDF, 3TC EFV M41L, K65R V106M, G190A I5V, V35T, T39E, S48T, V60I, S68G, K122E, D123G, S134N, I135V, S162C, K173T, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E297Q  
  GT00308796_2 TDF, 3TC EFV M41L, K65R V106M, G190A I5V, V35T, T39E, S48T, V60I, S68G, K122E, D123G, I135V, S162C, K173T, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E297Q  
GT00312394 GT00312394_1 D4T, 3TC EFV   V35T, T39E, S48T, A98S, D121H, K122E, K173T, D177E, I178L, T200A, Q207E, R211K, V245K, E291D, V292I, I293V  
  GT00312394_2 D4T, 3TC EFV   V35T, E36EA, T39E, E40ED, S48T, A98S, Y115X, D121H, K122E, K173T, D177E, I178L, T200A, Q207E, R211K, V245K, E291D, V292I, I293V  
GT00312709 GT00312709_1 D4T, 3TC EFV M184V, T215Y K101E, K103N, G190A P4S, E28K, V35T, T39E, S48T, K122E, D123S, I135T, S162G, K166R, K173T, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
  GT00312709_2 D4T, 3TC EFV M41L, M184V, L210L*W, T215Y K101E, K103N, G190A P4S, E28K, V35T, T39E, S48T, K122E, D123S, I135T, S162A, K166R, K173T, D177E, D192DN, T200A, Q207E, R211K, L228LF, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
GT00327585 GT00327585_1 D4T, 3TC EFV D67N, M184V L100I, K103N, E138K V35T, T39D, S48T, V90I, K122E, D123G, T165IV, K173A, T200A, Q207K, R211K, V245Q, D250DE, A272P, K281R, L283I, E291D, V292I, I293V  
  GT00327585_2 D4T, 3TC EFV D67N, M184V L100I, K103N, E138K V35T, T39D, S48T, V90I, K122E, D123G, T165IV, K173A, T200A, Q207K, R211K, V245Q, D250DE, A272P, K281R, L283I, E291D, V292I, I293V  
GT00328364 GT00328364 D4T, 3TC EFV M184V K103N T7TA, V35T, T39K, V90VI, K122E, D123N, I132L, I135T, E138A, T139A, S162C, K173A, Q174K, D177E, I178M, T200A, Q207E, F214L, P243S, V245Q, R284K, T286A  
GT00349623 GT00349623 D4T, 3TC EFV M41L, M184V, T215F K101E, V106M, G190A V35T, T39E, K43R, S48T, V60I, K122E, I135IK, K173A, D177E, I178M, T200A, Q207E, V245Q, A272P, Q278QH, E291D, V292I, I293V, V317A V254VA, K281*R, R284RG 
GT00361780 GT00361780 D4T, 3TC EFV M184V K103N, V108VI V35T, T39E, S48T, V60I, K122E, D123N, I135IM, K173A, D177E, V189VI, T200A, Q207D, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
GT00366729 GT00366729_1 D4T, 3TC EFV M184V K103N, K238T E28A, V35T, T39E, S48T, K122KE, K173A, D177E, T200A, I202V, Q207K, R211K, L228R, P243T, V245Q, A272P, K275R, K277R, Q278S, T286A, E291D, V292I, I293V, E297EK  
  GT00366729_2 D4T, 3TC EFV M184V, N348I K103N, K238T E28A, V35T, T39E, S48T, K122E, K173A, D177E, T200A, I202V, Q207K, R211K, L228R, P243T, V245Q, A272P, K275R, K277R, Q278S, T286A, E291D, V292I, I293V, E297KQ, E308K, L310C, E312K, Q334H, G335D V314G 
GT00373095 GT00373095_1 D4T, 3TC EFV   K20R, V35T, E36A, T39E, S48T, V60I, K122E, D123G, T165I, K173A, D177E, I178L, T200A, Q207D, R211K, V245Q, D250E, I257V, A272P  
  GT00373095_2 D4T, 3TC EFV M184V V106M, F227L K20R, V35T, E36A, T39E, S48T, V60I, K122E, D123G, T165L, K173A, D177E, I178L, T200A, Q207D, R211K, V245Q, I257V, A272P, T286A, E291D, V292I, I293V, E328K  
GT00376922 GT00376922 AZT, 3TC NVP M41L, D67N, M184V, T215Y K103N K20R, V35M, T39D, I135M, K173A, D177E, T200A, Q207D, R211K, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, E312Q  
GT00387892 GT00387892_1 D4T, 3TC EFV D67N, M184V K101E, V106M, F227L K20R, V35T, T39E, S48T, T69S, K122E, K173A, Q174K, D177E, T200A, E204D, Q207E, R211K, F214L, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
  GT00387892_2 D4T, 3TC EFV D67N, M184V K101E, V106M, F227L K20R, V35T, T39E, S48T, T69S, K122E, K173A, Q174K, D177E, T200A, E204D, Q207E, R211K, F214L, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
GT00396859 GT00396859 D4T, 3TC NVP   E6K, V35M, E36A, T39E, S48T, K122E, I135V, S162C, K173T, Q174K, D177E, T200A, Q207A, R211K, V245Q, A272P, E291D, V292I, I293V, I309X N306I 
GT00411974 GT00411974 TDF, 3TC EFV K65KR, K70E, M184V, K219KQ K103S, V106M E6K, K20KR, K32R, V35K, T39E, S48T, K102R, K122E, S162C, K173A, D177E, I178L, T200A, E204K, Q207D, R211K, L228R, V245Q, D250E, S251N, A272P, E291D, V292I, I293V  
GT00443767 GT00443767 D4T, 3TC EFV A62AV, K65R, Y115YF, M184V L100I, K103N K20KR, V35T, T39E, K122E, D123DN, I142K, K173T, Q197P, T200A, Q207E, L228LR, D250E, A272P, T286A, E291D, V292I, I293V, A304E  
GT0044838 GT0044838_1 None None D67N, K70R, M184V, T215F, K219E V106M, V108I, F227L K20R, V35T, E36A, T39E, S48T, E53D, V60I, K122E, D123G, A158S, K173A, D177E, T200A, Q207E, R211K, K223T, L228R, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
  GT0044838_2 None None  K101E, V106M, G190A P4S, K20R, V35T, T39E, S48T, A98S, K122E, D123N, E138A, I142V, E169Q, K173A, Q174K, T200A, I202V, Q207N, R211K, F214L, P243T, V245Q, A272P, K277R, Q278H, T286A, E291D, V292I, I293V, E297A, I326V, I329V, Q334H, G335D, Y342F, Q343K  
GT00451568 GT00451568 D4T, 3TC EFV   V35T, E36A, T39E, S48T, K122E, K173A, Q174K, D177E, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
GT00496439 GT00496439 AZT, 3TC EFV M41L, D67N, M184V, T215Y K103N K20R, V35M, T39D, I135M, K173A, D177E, T200A, Q207D, R211K, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, E312Q  
GT00506669 GT00506669_1 Unknown Unknown M184V G190A, P225H P4S, K11Q, V35T, T39D, K43R, S48T, K73X, F87X, K102R, K103X, K104X, Y115X, K122E, D123G, E138A, K173L, Q174K, T200A, Q207E, R211K, F214L, V245Q, A272P, K277R, R284K, E291D, V292I, I293V  
  GT00506669_2 Unknown Unknown M184V G190A, P225H P4S, K11Q, V35T, T39D, K43R, S48T, K73X, F87X, K102R, K103X, K104X, Y115X, K122E, D123G, E138A, K173L, Q174K, T200A, Q207E, R211K, F214L, V245Q, A272P, K277R, R284K, E291D, V292I, I293V  
GT00540737 GT00540737_1 Unknown Unknown   V35K, T39D, S48T, V60I, K122E, D123G, T165V, K173A, Q174K, D177E, T200A, I202V, Q207E, R211K, V245Q, E248D, A272P, I274V, K277R, Q278N, T286A, E291D, V292I, I293V, E308K, L310C, K311N  
  GT00540737_2 Unknown Unknown  K103N V35K, T39D, S48T, V60I, K122E, D123G, T165V, K173A, Q174K, D177E, T200A, I202V, Q207E, R211K, V245Q, E248D, A272P, I274V, K277R, Q278N, T286A, E291D, V292I, I293V S322I 
GT00543181 GT00543181 AZT, 3TC EFV M184V, T215Y A98G, K103N V35T, E36A, T39E, S48T, V60VI, K122E, D123N, I135L, K173A, D177E, T200A, Q207E, R211K, V245Q, K281R, L283I, T286A, E291D, V292I, I293V  

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