Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Kagan (2009)
Title Additional HIV-1 mutation patterns associated with reduced phenotypic susceptibility to etravirine in clinical samples.
Citation AIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 14
NumPts 14
Subtype B


Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
NRTI NNRTI M184V K101P, K103N V35M, K43N, K49R, K122E, I135L, E138G, D177E, I178M, V179I, G196E, F214L, D237N, A272P, K277R, T286A, E291D, V292I, I293V, E297R, K311R, G333E, Q334H, R356K, M357T, K366R, T369A, A376T, K390R, A400T  
10 10 NRTI NNRTI  K101P, K103S K20R, V35I, V60I, K122E, D177E, I178M, R211K, F214L, V245Q, A272P, K277R, T286A, E291D, V317A, M357T, A376T, K390R, A400T  
11 11 NRTI NNRTI M41L, M184V, L210W, T215D K101P, K103N E6D, V35E, S68G, K122E, D123E, I135K, D177G, T200R, F214L, L228H, A272P, K277R, T286P, I293V, E297A, K311R, A376T, A400T T296I 
12 12 NRTI NNRTI M41L, M184V, T215Y K101P, K103N K43N, D121H, K122E, I135V, K166R, D177E, R211K, F214L, V245T, A272P, K277R, Q278E, I293V, E297K, S322T, I329L, R356K, G359S, A376T, K390R, E399D, A400I  
13 13 NRTI NNRTI  K103S V35I, R83K, K122E, D123E, A158S, Q174H, I178M, G196E, T200I, R211G, F214L, A272P, K277R, K281R, I293V, E297K, I329V, G333E, Q334H, A360T, A376T, E399D, A400T  
14 14 NRTI NNRTI M41L, D67N, T69D, L210W, T215Y K101P E6D, V35I, E44D, R83K, V118I, K122E, D123E, K166R, I178L, R211K, F214L, D218E, A272P, K277R, G335S, G359S, A371V, A376S, S379C, A400T  
NRTI NNRTI M184V, N348I K101P, K103S K20R, V21I, V60I, K122Q, I135V, E138A, I178M, V179I, G196E, F214L, A272P, K277R, T286A, A288S, K323R, M357T, A376S, K390R, A400S  
NRTI NNRTI D67H, K70R, L74I, M184V, T215F, K219Q K101P, K103T K43Q, V60I, T69N, K122E, I135T, E138Q, D177G, I178M, V179I, G196E, F214L, L228H, Q242L, V245E, A272T, K277R, I293V, Q334H, G335D, R356K, G359S, V365I, A376T, T386M, A400T  
NRTI NNRTI K65R, M184V, T215D K101P, K103S E6K, V35I, S68G, T69I, K104R, G112A, K122E, I135T, T200I, F214L, K277R, I293V, R358K, A376T, A400T  
NRTI NNRTI M41L, M184V, L210W, T215Y K101P, K103S T7I, K20R, V35I, K43E, V60I, S68G, K122P, K166R, D177E, I178L, T200A, F214L, V245E, A272P, K277R, I293V, E297R, G333E, Q334H, G335S, R356K, G359S, A371V, A376T, K390R, A400T  
NRTI NNRTI M184V K101P V35I, K122I, I178L, V179I, F214L, E248D, K249R, A272P, K277R, K366R, A376T, T386A, A400T  
NRTI NNRTI M41L, M184V, L210W, T215Y, N348I K101P, K103S T39A, D121H, K122E, K166R, V179I, Q207A, R211K, F214L, V276I, K277R, Q278H, T286A, D324E, R356K, M357T, A376T, T386V, E399K, A400V  
NRTI NNRTI D67G, T69D, K70R, M184V, T215F, K219Q K101P, K103S K11R, V60I, V118I, K122E, D123N, Q174R, N175Y, D177N, V179I, T200E, I202V, F214L, A272P, K277R, I293V, E297K, D324E, R356K, T369V, I375V, A376T, T386A, K390R, A400I  
NRTI NNRTI M184V K101P, K103N, V108I V60I, K122E, I135V, T139M, S162G, R211K, F214L, V245E, D250E, A272P, K277R, I293V, E297A, I329L, Q334E, M357T, A376S, K390R, A400T