<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Parboosing (2011)
Title Resistance to antiretroviral drugs in newly diagnosed, young treatment-naive HIV-positive pregnant women in the province of KwaZulu-Natal, South Africa.
Citation J Med Virol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 56
NumPts 56
Subtype C

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
Pat001 HRS100 None None   T27S, V35T, E36A, T39E, S48T, K122E, D123N, K173V, Q174K, D177E, T200A, Q207E, V245Q, A272P, I274V, K277R, T286A, E291D, V292I, I293V  
Pat002 HRS160 None None   V8I, V35T, E36A, T39D, S48T, V60I, K122E, D123N, K173A, Q174KR, D177E, T200A, I202V, Q207AE, R211K, F214FL, V245Q, A272P, K277R, T286TA, E291D, V292I, I293V, Q334E  
Pat003 HRS156 None None   E6A, V8I, V35T, T39E, S48T, K122E, D123S, E169D, K173A, Q174K, D177E, T200V, Q207A, R211K, V245Q, D250DE, A272P, K277R, T286A, E291D, V292I, I293V  
Pat004 HRS55 None None   V35T, E36A, T39D, S48T, V60I, K122KE, D123S, I135V, T165I, K173AT, Q174K, D177E, T200A, Q207K, R211Q, V245Q, A272P, K277R, K281R, T286A, E291D, V292I, I293V, I326V, Q334D  
Pat005 HRS45 None None   V35R, T39A, S48T, K122E, D123S, I142V, S162A, K173A, Q197K, T200A, Q207D, R211K, V245Q, E248T, D250E, S251N, A272P, Q278Y, R284K, E291D, V292I, I293V P4PHSY, T253S, G273R 
Pat006 HRS29 None None   P4H, V35T, E36A, T39E, S48T, V60I, K102Q, K122E, D123S, I135V, I142T, K173A, Q174K, D177K, T200A, I202V, Q207E, R211K, F214L, V245Q, A272P, K277G, E291D, V292I, I293V  
Pat007 HRS28 None None   V35T, E36V, T39E, E40ED, S48T, I50IV, V60VI, K122KE, D123DG, I135V, E138EG, T165TI, K166KR, K173AT, Q174K, I178IM, I195IL, T200A, Q207AE, R211KQ, F214FL, I244IV, V245KLMQ, A272AP, K275KR, K277KR, R284RK, T286TA, E291D, V292I, I293V, K311KR, D324DE, Q334EK  
Pat008 HRS11 None None   V35T, E36EA, T39E, E40ED, S48T, V60I, K122E, D123DGNS, T165TI, K173A, Q174K, D177E, V179VI, T200A, Q207A, R211A, F214FL, V245KQ, A272P, K275KQ, Q278QH, T286AV, E291D, V292I, D324DE, Q334QDEH  
Pat009 HRS43 None None   T27TS, V35T, E36A, T39E, S48T, V60I, V118VI, K122KE, I135T, S162A, K173A, D177E, G196E, T200A, Q207E, F214L, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, I329IL  
Pat010 HRS205 None None   K20R, V35T, T39E, E40D, S48T, E53D, K122E, D123S, I135T, S162W, K173A, Q174K, D177E, I178V, T200A, Q207A, R211RK, V245Q, D250T, A272P, K277R, T286A, E291D, V292I, I293V  
Pat011 HRS204 None None   K20R, V35T, E36A, T39E, S48T, V60I, K122E, D123S, K173A, D177E, T200E, Q207E, R211K, V245Q, K281R, L283I, T286A, E291D, V292I, I293V, D324E  
Pat012 HRS203 None None   V35T, E36A, T39E, S48T, K64R, K122E, A158S, T165I, K173A, Q174K, D177E, T200E, Q207E, R211K, P243PS, V245Q, S268C, A272P, K277R, E291D, V292I  
Pat013 HRS201 None None   E6A, V8I, L34I, V35T, E36A, T39E, S48T, V60I, A98S, D121Y, K122E, S162C, K173A, Q174K, D177E, T200A, Q207E, V245Q, L260LV, A272S, T286A, E291D, V292I, I293V  
Pat014 HRS193 None None   V35T, T39E, S48T, V60I, K122E, D123G, A158S, K173T, D177E, G196E, T200A, E204K, Q207E, R211RK, V245K, A272P, T286A, E291D, V292I, I293V, E297A, V317A, D324E  
Pat015 HRS192 None None   V8I, V35K, T39E, S48T, V60I, V118I, K122E, I135V, I159V, K173V, Q174K, D177E, T200A, Q207A, F214L, V245Q, A272P, K275R, K277R, Q278N, E291D, V292I, I293V  
Pat016 HRS182 None None   V35T, E36A, T39D, S48T, E53D, V60I, D123E, E138A, I142V, S162FY, K173V, Q174K, T200A, Q207E, R211K, F214L, A272P, K277R, T286A, E291D, V292I, I293V, P313T, S322A, D324E  
Pat017 HRS175 None None   V35T, E36A, T39E, S48T, V60I, D123N, K173T, Q174K, D177E, T200A, Q207A, R211K, V245IM, A272P, K277R, T286A, E291D, V292I, I293V  
Pat018 HRS165 None None   V35T, E36A, T39E, S48T, K122E, D123S, A158S, T165I, K173A, Q174K, D177E, G196E, T200A, Q207E, V245Q, E248D, D250E, A272S, K277R, T286A, E291D, V292I, I293V, K311R, V317A, D324E, I329L  
Pat019 HRS164 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173A, Q174K, D177E, T200A, Q207A, R211K, F214L, V245E, D250E, A272P, K277R, T286TA, E291D, V292I, I293V, E297A, Q334E  
Pat020 HRS162 None None   V35T, E36A, T39D, S48T, V60I, K122E, D123S, K166R, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245E, A272PS, I274IV, T286A, V292I  
Pat021 HRS161 None None   V35T, T39E, E40D, S48T, V60I, D123E, I135V, S162C, K173A, D177E, T200A, Q207E, V245E, A272P, K277R, T286A, E291D, V292I, I293V, P294Q, E297K, L310I  
Pat022 HRS157 None None   V35T, E36A, T39D, S48T, V60I, K122E, D123S, K166R, K173A, D177E, T200A, Q207N, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, I329L  
Pat023 HRS152 None None   K11Q, V35T, E36A, T39E, D121Y, K122E, D123G, I135T, S162C, K173AV, D177E, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, R307K, K311KT  
Pat024 HRS144 None None   V35T, E36A, T39E, S48T, V60I, T69S, K122E, D123S, I135V, I142IM, E169D, K173A, Q174K, D177E, I178M, T200A, Q207D, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
Pat025 HRS140 None None   V35T, E36A, T39E, S48T, A98S, K122E, D123G, I135T, T165I, K173A, D177E, I178V, T200A, Q207E, V245H, A272P, V292I, I293V, L303M  
Pat026 HRS134 None None   M16ML, V35T, E36A, T39E, S48T, V60VI, D123N, S162C, K173A, Q174K, D177E, T200A, Q207N, R211K, D218E, V245K, A272P, E291D, V292I, I293V, E297K, I326V  
Pat027 HRS114 None None   V35T, E36A, T39E, S48T, K49R, D123E, K173I, Q174K, D177E, T200A, Q207E, P243T, V245K, E248D, D250E, A272S, K277R, T286A, E291D, V292I, I293V, D324E  
Pat028 HRS105 None None   P4S, V35T, E36A, T39D, S48T, S162C, K166R, K173A, Q174K, G196E, T200A, Q207E, R211K, V245Q, A272P, E291D, V292I, I293V, V314A, H315Q  
Pat029 HRS102 None None   P4PS, E6K, V35T, E36A, T39E, S48T, V60I, K122E, D123G, I135V, I142IV, S162C, K173A, D177E, T200A, Q207E, R211K, V245E, A272P, T286A, E291D, V292I, I293V, D324E  
Pat030 HRS99 None None   V8I, V35T, E36A, T39E, S48T, V60I, D123G, K173T, D177E, T200A, Q207A, R211K, F214L, V245Q, D250E, A272P, K275Q, K277R, T286A, E291D, V292I, I293V  
Pat031 HRS94 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123G, I135R, K173T, D177E, T200A, Q207E, R211K, V245K, D250E, A272P, K277R, T286A, E291D, I293V  
Pat032 HRS91 None None   M16T, K20R, V35T, E36A, T39D, K122E, D123G, A158S, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, T286A, E291D, V292I, I293V, I329V  
Pat033 HRS90 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173T, Q174K, D177E, T200A, Q207E, R211K, V245E, A272AP, I274IV, Q278N, T286V, E291D, I293V  
Pat034 HRS89 None None   V35T, E36A, T39D, K43R, S48T, V60I, K122E, D123G, K173I, Q174K, D177E, I178V, T200A, Q207A, R211K, V245Q, A272S, K277R, T286A, E291D, V292I, I293V, P294Q, V317A, Q334E  
Pat035 HRS88 None None   V35T, E36A, T39E, S48T, K122E, D123S, I135V, S162C, K173A, D177G, T200A, R211K, V245Q, A272P, I274V, T286A, K287KR, E291D, V292I, I329L  
Pat036 HRS85 None None   V35T, T39D, S48T, V60I, K173T, Q174K, D177E, Q197K, T200E, Q207E, R211K, F214L, V245E, D250E, A272S, K277R, T286A, E291D, V292I, I293V  
Pat037 HRS84 None None   V35K, T39E, S48T, V60I, W88C, K122E, D123S, I142V, I159V, K166KR, K173A, D177E, G196E, T200A, Q207E, F214L, V245Q, A272S, K277R, T286A, E291D, V292I, I293V, K311R, D324E  
Pat038 HRS79 None None   V8I, V35T, E36A, T39E, V60I, K122E, D123G, I132V, K166R, K173A, D177E, T200A, R211K, I244V, V245Q, A272P, K277T, K281R, T286A, E291D, V292I, I293V  
Pat039 HRS58 None None   V35T, E36A, T39D, S48T, V60I, V118I, D121H, K122E, E138A, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q, E248DN, A272P, K275R, Q278H, T286A, E291D, V292I, I293V, I329L  
Pat040 HRS52 None None   P4S, V35T, E36A, T39E, S48T, V60I, I142V, A158AS, K173A, Q174K, D177E, V179I, G196E, T200A, Q207E, V245Q, A272P, T286TA, E291D, V292I, I293V, V317A  
Pat041 HRS48 None None   V35T, E36A, T39E, S48T, K122E, I135T, S162C, K173A, D177E, T200A, Q207N, R211K, V245Q, A272P, K275Q, V276T, T286A, E291D, V292I, I293V, L310I  
Pat042 HRS47 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173AV, Q174KR, D177E, I178M, T200A, Q207A, R211RK, V245Q, A272P, K277R, T286A, A288T, E291D, V292I, V317A  
Pat043 HRS46 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123G, I142IV, K173T, Q174K, D177E, I178M, T200A, E204D, Q207A, R211K, V245K, A272P, Q278H, T286V, E291D, V292I, I293V, D324E, Q334L  
Pat044 HRS44 None None   V8VI, V35T, E36A, T39D, S48T, V60I, K122E, K173T, D177E, T200A, Q207A, R211K, F214L, V245Q, A272P, K277R, E291D, V292I, I293V  
Pat045 HRS37 None None   V35T, E36A, T39E, S48T, V60I, K82KR, V118I, K122E, D123DG, K173A, D177E, T200A, Q207A, R211K, F214L, V245Q, I257IV, A272P, T286A, E291D, V292I, I293V, Q334C  
Pat046 HRS31 None None   V35T, E36A, T39E, S48T, I50IV, V60I, K122E, D123G, T165I, K173A, D177E, T200A, Q207A, R211K, F214L, V245Q, D250E, A272P, Q278N, K281R, T286A, V292I, I293V  
Pat047 HRS30 None None   V35T, E36A, T39E, S48T, K122E, E169K, K173E, D177E, T200A, Q207E, V245Q, T286A, E291D, V292I, I293V, I329L  
Pat048 HRS25 None None  K103N V35T, E36A, T39E, S48T, K102R, K122KE, D123N, T165I, K173AT, Q174R, D177E, T200A, Q207E, V245K, E248D, A272P, K275Q, E291D, V292I, I293V, Q334H  
Pat049 HRS18 None None   V35T, E36A, T39D, S48T, K122E, D123N, K173A, Q174K, D177E, T200A, Q207D, R211K, P243T, V245Q, A272S, T286A, E291D, V292I, S322T, Q334H  
Pat050 HRS16 None None   P4S, K20R, V35T, E36A, T39E, S48T, V60I, K173T, Q174R, D177E, G196E, T200A, Q207E, V245K, A272P, K277KR, T286A, E291D, V292I, I293V  
Pat051 HRS9 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123DG, I135V, I142T, K173A, Q174K, D177E, I178IL, T200A, Q207A, R211K, V245Q, A272S, K277R, K281R, T286A, E291D, V292I, I293V  
Pat052 HRS8 None None   V8I, K32R, V35T, T39K, S48T, K122E, D123S, S162C, K173T, Q174K, D177E, T200A, Q207E, V245Q, E248D, A272P, K277R, E291D, V292I, I293V, I329V  
Pat053 HRR41 None None   V35T, E36EA, T39D, V60VI, K122E, D123GS, I142V, S162N, K173A, D177E, T200A, Q207E, V245Q, E248N, A272S, Q278QH, T286A, E291D, V292I, I293V, E312EGKR H96HQ 
Pat054 HRR27 None None   V35T, E36A, T39D, S48T, V60I, I135V, T165I, K173V, D177G, T200A, I202V, Q207E, R211K, V245Q, A272P, I274IV, K277R, T286A, V292I, I293V  
Pat055 HRR22 None None   V35T, T39K, E40D, S48T, V60I, K122E, D123DGNS, K173V, Q174K, D177E, T200A, Q207D, R211K, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294PQ, K311R  
Pat056 HRS210 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123G, T165TI, K173A, D177E, T200A, Q207A, R211K, F214L, V245Q, D250E, A272P, Q278N, K281KR, T286A, V292I, I293V