Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Moussa (2010)
Title First data on HIV-1 resistance mutations to antiretroviral drugs in Central African Republic.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 21
NumPts 21
Subtype A, CRF11_cpx, CRF01_AE, J, CRF25_cpx, CRF02_AG, G, A + J, CRF06_cpx


Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
18-CP001006 D4T, 3TC NVP  K103N V35T, T39K, K122E, D123S, K173T, Q174K, D177E, L193F, T200E, I202V, Q207E  
10 62-BAW1 RTI RTI F116Y, Q151M, M184V Y181C V35T, E36D, T39K, K43E, K49R, S68G, K173T, Q174K, D177E, V179I, Q207A, R211S, H221Y, V245K A129AV 
11 9-CP001045 Unknown Unknown M41L, V75I, M184V, T215Y Y181C V35T, T39R, K43E, K101R, D121H, K122E, D123S, I132L, F171FY, K173A, Q174K, V179I, E194D, Q207A, R211S, H221Y, E224D, V245E  
14 09861F1 RTI RTI   K32KQ, V35T, T39TKN, E40ED, I50IV, K122E, D123N, I142V, K173AT, D177E, I178IL, I195IL, T200E, I202V, Q207K, R211KQ, F214FL, V245Q, E248D, K249Q V60VIM, V148VA 
17 01771M8 RTI RTI   V35T, E53D, K122E, D123DG, S162Y, K173L, D177E, G196K, T200TA, Q207A, R211S, V245Q P97PT 
5100931-F1 AZT, 3TC NVP D67N, K70R, M184V, T215FI, K219E Y188L, G190A V35T, T39A, E40D, T69N, K102M, K122E, D123N, K166R, K173T, Q174QR, D177E, I178M, T200E, I202V, E203EK, E204K, Q207E, R211K, P243T G99GR 
20 8-CP001029 RTI RTI   V35T, E40D, K49R, V60I, K122E, I135V, S162A, K173T, Q174K, D177G, T200A, Q207N, R211K, F214L I94IT 
22 39-0851F1 RTI RTI   V35T, E40D, K49R, V60I, K66KR, R83K, K102Q, D123E, K166R, Q174K, D177E, I178M, G196E, T200A, Q207N, R211K, Q242H  
23 20-CP001266 D4T, 3TC NVP M184V, K219KE A98AG, K103N, Y181C K20KR, V35T, T69TN, K101KR, K102KN, V106I, K122E, D123S, K173A, Q174K, D177E, T200E, I202V, Q207N, R211K, L228HR, P243T  
24 19-CP001233 D4T, 3TC NVP K65R, V75I, M184V Y181I V35T, V60I, S68G, D123E, I132L, I135T, K173R, D177E, V179I, T200E, I202V, Q207K, R211K, F214L Q174C 
25 11-CP001021 D4T, 3TC NVP M184V, T215F A98G, K101E, Y181C, G190A E28K, K32E, V35T, T39M, K122E, D123N, I135T, I142V, K173A, Q174K, D177E, I178M, T200A, Q207A, V245K  
27 26-CP001080 D4T, 3TC NVP M184V, T215F K103N, V108I, Y181C L34I, V35T, T39L, K122P, E138Q, S162SC, K173T, Q174K, D177E, I178L, T200Q, Q207E, R211K, E224D, V241I  
28 14-CP001245 D4T, 3TC NVP M184V K101E, V108I, F227L V35T, K49R, T69S, K122E, D123S, I135T, T139R, S162H, K173S, D177E, G196E, Q207A, R211S, L228F, V245Q  
29 33-CP001666 Unknown Unknown K70R, V75S, M184V, K219E K103N, Y181C V35T, K122E, D123S, K173A, Q174K, N175Y, D177E, T200E, I202V, Q207N, R211K, L228R, P243T  
38-0147M1 AZT, 3TC EFV  K103N, V108I V35T, T39Q, D121H, K122E, I142V, A158S, K173S, D177E, G196E, T200K, Q207A, R211S  
30 34-CP001259 Unknown Unknown M184V V179D, Y188L K20R, V35T, T39N, D121H, K122E, I135M, I142V, S162H, K173S, Q174K, D177G, G196E, T200I, Q207A, R211S, H221Y, P243S, V245Q  
23-CP001745 D4T, 3TC EFV M184V, L210W K101E, Y181C, G190S V35T, T39L, T107S, K122E, D123S, K173A, D177G, T200A, Q207E, R211K  
30-CP001046 D4T, 3TC NVP M184V K103N K32R, V35T, T39A, E40D, K49R, V60I, K122E, D123N, I135T, S162C, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K  
03121F1 D4T, 3TC NVP D67G, K70R, M184V, T215I, K219E Y181C V35T, T39R, K43E, K49R, S68G, V106I, K122E, D123N, I135T, T139V, K173A, Q174K, D177E, I178L, Q207A, R211S, K238R, V245E  
52-293-F12 D4T, 3TC NVP M184V K103N V35K, T39D, M41V, V60I, I135T, I142V, K173A, Q174K, D177E, T200A, Q207G, R211K, D218E  
22-CP001020 NRTI None  A98AG, Y181C V35T, T39N, K104KR, K122V, D123N, K173T, D177E, I178IL, V179VI, I195IT, T200K, I202V, Q207E, K223KE R72RK, K154KQ, E169EV