<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Chamberland (2012)
Title Transmission of HIV-1 drug resistance in Benin could jeopardise future treatment options.
Citation Sex Transm Infect
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 127
NumPts 127
Subtype CRF02_AG, G, K, CRF06_cpx, A, CRF01_AE, J


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Page 1   from Isolate 1 to Isolate 100 from Total 127 Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
C401S C401S None None   V35T, E40D, K49R, V60I, V90I, I135V, S162A, K173T, Q174R, D177E, I178M, T200A, Q207E, V245K, K277T, K281R, T286V, E291D, I293V, P294T, E297R, I326IV, G335GD, R356RK, R358K, G359S, T369A, A371AV, I375V, K390KR, K395KR, A400AT, T403M  
C404S C404S None None   V21I, V35T, T39A, V118VI, I135T, I142V, S162SN, T165I, K173T, Q174K, D177E, G196E, T200A, Q207E, R211K, F214L, P243T, V245Q, E248D, D250E, A272P, K275R, Q278QH, K281R, T286A, E291D, V292I, I293V, P294T, L295LM, L310LI, G335D, Q343H  
C405S C405S None None   E6D, K11T, V35M, T39E, K49KR, E53D, S68N, K122E, D123N, S162SHNR, K166R, F171Y, K173A, Q174KR, D177E, I178M, Q207E, R211K, V245Q, D250E, S251N, A272P, K277R, T286A, A288T, E291D, V292I, I293V, E297A, K311R  
C406S C406S None None   V35T, S48T, K49KR, V60I, D121H, K122E, I135T, S162A, Q174E, D177E, I178V, T200A, Q207G, R211K, V245K, K277R, K281KR, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, K366R, A371V, I375V, V381I, K390R, K395KR, E396D, A400T, T403M, E432D, V435I  
C407S C407S None None   K20R, V35T, T39K, V60I, V118M, D121Y, K122E, I142T, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q, E248D, D250E, A272P, Q278H, K281R, T286A, E291D, V292I, I293V, P294S, E297A, L301M, I309L, I329V, Q334I, G335E, F346Y, R356K, M357R, R358G, G359S, A371V, T386I, K390R, Q394R, A400V, K431T, V435P  
C409S C409S None None   V35T, T39K, K43E, V60I, D123E, I142V, K173I, Q174K, D177E, Q207E, R211K, V245Q, A272P, K281R, T286A, E291D, I293V, P294T, G335D, F346Y, R356K, M357V, G359S  
C411S C411S None None  G190GA V35T, E36D, V60I, D123N, I135IT, I142V, S162A, K166R, K173S, D177E, V179T, T200A, Q207A, F214L, V245HQ, K277R, T286A, E291D, V292I, I293V, P294PS, S322T, G335D, R356K, M357R, G359S, T369A, A371V, I375V, A376S, T377I, K390R, K395R, A400T  
C412S C412S None None   V35T, T39A, E40D, D123E, I135V, I142V, S162A, E169Q, K173T, Q174E, D177E, T200A, Q207N, V245R, K249Q, T286A, E291D, V292I, I293V, K311R, S322T, G335D, R356K, M357R, G359S, A371V, I375V, T377L, K390R, K395R, T403M, E413D, V435M, E438X  
C413S C413S None None   V35T, E36D, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, T200A, E204D, Q207D, R211K, V245Q, T286A, E291D, V292I, I293V, P294T, P321S, S322T, I326V, G335D, A355S, R356K, M357K, R358K, G359S, A371V, I375V  
C415S C415S None None   V35T, K122P, D123N, K173I, Q174K, D177E, T200A, Q207E, R211K, P243S, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297A  
C417S C417S None None   V35T, V60I, I135V, I142V, S162A, K173T, Q174K, D177E, T200A, Q207E, V245Q, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357R, G359S, A371V, K390R, T403M  
C418S C418S None None   K20R, V35T, T39L, V60I, I135V, A158S, S162A, T165I, K173A, Q174K, N175Y, D177DE, T200A, Q207E, R211K, V245K, D250DE, S251C, A272P, T286A, E291D, V292I, I293V, K311KR, S322A, I326V, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, A376S, T377L, T386I, Q394R, A400V, E413D, K424Q  
C421S C421S None None   V21VI, V35T, E36D, T39K, V60I, I135T, S162A, K173T, Q174N, D177E, T200A, Q207E, V245M, T286A, E291D, V292I, I293V, P294T, E312D, I326V, G335D, M357K, G359S, K366R, T369V, A371V, I375V, A376V, T386A, K390R, T403M  
C422S C422S None None   V35T, E36D, K122Q, D123E, S162A, K173T, Q174R, D177E, I178IM, T200A, Q207E, R211K, P243T, V245Q, K277R, T286A, E291D, I293IV, P294T, S322A, G335D, R356K, M357R, G359S, A371V, I375V, A376S, K390R, T403Q, V435I  
C423S C423S None None   V35T, I135V, S162A, K173T, Q174K, D177E, T200A, Q207S, R211K, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, L325I, G335D, R356K, M357K, G359S, K366R, T369V, A371V, I375V, A376T, K390R, T403M, E432D, V435A  
C424S C424S None None   E6ED, K11KT, K20R, V35T, E36A, T39D, V60I, K102E, D123N, I135T, I142V, S162CY, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, D250E, A272P, K275R, T286A, V292I, I293V, E297A, V317A, F346Y, M357V, G359S, K390R  
C425S C425S None None   V35T, T39L, V60I, I135L, S162A, K173T, Q174N, D177E, I178M, I195IV, T200A, Q207G, R211K, V245H, A272P, K281R, T286A, E291D, V292I, P294T, S322T, I329V, G335D, R356K, M357R, G359S, K366R, T369A, A371V, T377L, K390R, K395R, E413D, E432D  
C427S C427S None None   K11KR, E28K, K32E, V35T, K122E, D123N, I135V, I159IV, S163ST, K173T, D177DE, T200A, Q207A, R211K, V245K, A272Q, K281R, E291D, V292I, I293V, E297P, I329V, Q334L, G335D, A355S, R356K, M357R, R358K, G359A, T369S, A371V, V372I, A376S, T377M, K390R, K395R, A400T, E404D, K431Q, V435A  
C428S C428S None None   V35T, S48T, K49R, V60I, D121H, K122E, I135T, S162A, Q174E, D177E, I178V, T200A, Q207G, R211K, V245K, K277R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, K366R, A371V, I375V, V381I, K390R, K395R, E396D, A400T, T403M, E432D, V435I  
C429S C429S None None   K22R, V35T, T39S, V60I, S68T, V118I, K122E, I135L, A158S, S162A, K173T, Q174R, D177E, T200A, Q207E, R211K, V245Q, K275Q, R284K, T286A, E291D, V292I, I293V, P294T, S322T, D324E, Q334P, G335D, F346Y, R356K, M357R, G359S, I375V, K390R, E432D  
C430S C430S None None   V35T, E36A, V60I, I135V, S162A, K173A, Q174K, D177E, I178M, Q207E, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, V317A, S322T, G335D, M357R, G359S, K390R, K395R, A400T, T403M  
C431S C431S None None   V35T, K122P, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, E203D, Q207A, R211K, P243T, V245Q, D250E, K281KR, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, S379G, K390R, E399D, T403M, W414R  
C432S C432S None None   K20R, V35T, T39K, K43E, K49R, V60I, D121Y, K122E, I135T, T165I, Q174E, T200A, E204K, Q207E, L210M, R211A, F214L, P243T, V245Q, D250E, K275Q, K277R, T286A, E291D, V292I, I293V, P294T, L295M, S322A, G335D, R356K, M357K, G359S, A371V, I375V, A376T, K390R, E399D, A400T, E404D  
C434S C434S None None   P9S, E28EA, V35T, E36D, T39A, I135V, S162A, K173T, Q174K, D177E, V189I, T200A, I202V, Q207E, L210M, F214L, V245Q, E248D, A272P, K275R, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357R, R358K, G359S, K366R, T369A, A371V, I375V, A376T, T377M, K390R, K395R, A400T, T403M, E432D  
C435S C435S None None   E6K, V35T, E36A, T39K, K43E, K122E, I135T, I142V, S162Y, K173S, D177E, V179I, T200I, I202V, E204Q, Q207E, R211K, F214L, V245Q, E248D, Q278H, K281R, T286A, E291D, V292I, I293V, E312D, G335D, K350R, M357K, G359S, T369V, A371V, I375V, A376V, T377R, A400T, T403M, E404D, W410C  
C436S C436S None None   V35T, S48E, V60I, D123E, I135V, S162A, K173I, Q174K, D177E, T200A, Q207E, R211K, K223KR, V245Q, E248D, K275Q, V276I, T286A, E291D, I293V, P294T, P313S, S322T, I326V, G335D, F346L, A355S, M357K, G359S, A371V, I375V, T377I, K390R, T403M, V435L  
C437S C437S None None   V35T, E36D, K49R, V60I, I135V, I159V, K173T, Q174K, D177E, Q197H, T200A, Q207E, R211K, V245Q, P247A, A272P, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357R, G359S, A371V, I375V  
C438S C438S None None   V35T, V60I, D123E, I135L, S162A, K173T, Q174K, D177E, T200A, Q207EG, R211K, V245E, K277R, T286A, V292VI, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, A360T, K366KR, A371V, I375V, A376V, K390R, A400T, T403TM, E432D  
C440S C440S None None   V21I, T27S, K32R, V35T, T39S, K49KR, V60I, K122E, I142V, Q174R, N175Y, D177E, I178M, T200E, Q207E, R211K, V245K, D250E, A272S, K277R, T286A, E291D, V292I, I293V  
C441S C441S None None   V35T, T39L, S162A, K173A, Q174K, D177E, T200A, Q207G, R211K, P243Q, V245Q, K275R, V276VI, Q278H, R284K, T286A, E291D, I293V, P294T, R307K, E312Q, S322T, G335D, R356K, M357R, G359S, T369S, T377L, K390R, K395R, T403M  
C442S C442S None None  V108VI V35T, T39A, E40D, V60I, I135V, I142V, S162A, K173AT, Q174E, D177E, T200A, P243T, V245Q, Y271F, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357R, G359S, A371V, K390R, T403R, K431AT  
C443S C443S None None   K11E, V35T, E36D, T39R, K43E, V60I, K102E, D123N, S162A, K173L, Q174K, P176T, D177E, V179T, V189I, T200A, I202V, Q207A, R211K, F214L, V245Q, E248D, K277R, T286A, E291D, V292I, I293V, V317A, P321S, I326V, R356K, M357K, G359S, Q367E, E370Q, A371V, I375V, K390R, A400T, T403M, E404D, E432D, V435I  
C444S C444S None None   K20R, V35T, V60I, K64R, D67X, K122E, D123S, I135V, T165I, K173I, Q174K, D177E, I178M, T200A, Q207E, R211K, V241I, V245Q, D250E, S251D, A272Q, V276I, T286A, E291D, V292I, I293V, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, S379G, V381VI, T386V, K390R, Q394R, A400V, E413D  
C446S C446S None None   V21I, K32KR, V35T, E36D, K122E, D123N, A158S, S162A, F171Y, K173AT, Q174K, D177E, T200A, Q207E, V245Q, A272T, K277R, T286A, E291D, V292I, I293V, P294T, L310I, S322T, I326V, G335D, R356K, M357KR, G359S, T369TA, A371V, I375V, A376T, T377M, K390R, A400T, T403M  
C447S C447S None None   V35T, V60I, K122E, D123N, I135T, S162A, K173I, Q174K, D177E, T200A, Q207G, R211K, F214L, V245Q, K249Q, T286A, E291D, V292I, I293V, S322T, I326V, G335D, R356K, M357R, G359S, A371V P150T 
C450S C450S None None   V8I, K20R, V35T, E36A, T39E, E40D, I135T, S162C, K173T, Q174R, D177E, I178M, Q207A, R211K, F214L, V245Q, A272P, K277R, Q278H, T286A, E291D, V292I, E297A, V317I, I326V, F346Y, M357V, G359S, V365VI, T377V, K390R  
C453S C453S None None   K20R, V35T, T39K, E40D, V60I, K104R, D121H, K122E, I135V, K173KR, Q174K, D177E, I178L, T200A, Q207EK, R211A, F214L, V245H, E248D, D250E, A272P, I274V, Q278H, K281R, T286A, E291D, V292I, I293V, E297A, L301M, I326IT, A327V, I329V, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, I375V, T386I, A400V, K431T  
C454S C454S None None   E6EV, V21VD, V35T, E36DV, K49R, K122E, D123N, I135V, S162A, K166R, E169K, K173A, Q174E, D177E, I178M, T200A, Q207A, R211K, P243S, V245K, E248D, K275KR, T286A, E291D, I293V, P294T, S322T, G335D, R356K, M357K, G359S, V365I, A371V, I375V, S379SG, K390R, T403M T7HILN 
C455S C455S None None   K11T, V35T, T39K, K43E, K122E, D123S, S162SN, K173S, Q174K, D177E, T200A, Q207A, R211K, V245L, E248D, A272S, K281KR, T286A, E291D, I293V, E312T, I326V, G335D, M357K, G359S, K366R, T369A, I375V, A376G, T377Q, K395R, A400T, T403S  
C456S C456S None None   V35T, E36ED, E40D, K49R, V60I, I135V, S162A, K173T, Q174K, D177E, G196E, T200V, Q207E, L210M, E224D, V245Q, A272P, K281R, T286A, E291D, V292I, I293V, P294T, R307K, E312D, S322T, I326L, G335D  
C458S C458S None None   V35T, E36A, T39K, K43E, D123E, I135V, S162A, Q174R, D177E, T200A, Q207E, R211K, V245Q, E248N, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326IV, G335D, R356K, M357K, G359S, A371V, I375V, A376T, K388R, K390R, T403M, E432D, V435A  
C459S C459S None None   V35T, V60I, K122A, D123S, I135T, K173A, Q174K, D177E, T200E, I202IV, Q207D, V245Q, E248D, D250DE, A272P, T286A, E291D, V292I, I293V, P294A, E297K, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359A, V381I, T386V, Q394R, A400V, V423L  
C460S C460S None None   V35T, T39D, E40D, K43R, K122N, K173I, Q174K, D177E, V179I, Q207E, V245Q, E248D, T286A, E291D, V292I, I293V, P294T, F346Y, M357E, G359S, I375V, T377L, K390R, A400T, E404D, Q428P, V435I  
C461S C461S None None   V35I, K49R, V111I, D123E, I135V, S162A, Q174T, D177E, I178L, T200A, Q207E, R211K, F214L, P243S, V245Q, T286A, E291D, I293V, R307K, S322T, G335D, I341V, R356K, M357R, G359S, A371V, I375V, A376T, T386P, K390R, K395R, E399D, T403M, E432D, V435M  
C464S C464S None None   V35T, E36A, T39K, K43E, V60VI, I135T, I142V, S162A, K173T, Q174R, D177E, I178L, T200A, Q207E, R211K, V245Q, E248N, T286A, E291D, V292I, I293V, S322T, I341V, R356K, M357K, R358K, G359S, A371V, I375V, T377M, I380IV, K388R, K390R, T403M  
C465S C465S None None   K20R, V35T, T39K, E40D, V60I, K173T, Q174K, D177E, I178V, T200A, Q207D, R211K, F214L, V245Q, E248D, D250E, S251D, A272P, I274V, Q278H, K281R, T286A, E291D, V292I, I293V, E297A, L301M, D324E, L325I, Q334P, G335D, F346Y, R356K, M357R, R358G, G359S, A376S, T386I, K390R, Q394R, A400L  
C467S C467S None None   V35T, V60I, K104R, D121H, K122E, D123S, S162N, K166R, K173T, Q174R, D177E, T200A, Q207N, R211K, V245H, E248N, D250E, K277R, T286A, E291D, V292I, I293V, E297K, A304E, D324E, I329V, Q334P, F346Y, R356K, M357R, R358G, G359S, K366R, A376S, T386V, Q394R, A400V, E413D, K431T, V435L  
C469S C469S None None   K32KR, V35T, V60I, I135T, K173E, Q174K, D177E, I178M, T200Q, Q207E, R211K, V245Q, K281R, T286A, E291D, I293V, E297A, Y339F, F346H, R358K, G359S, T377Q, K390R, A400T  
C470S C470S None None   E28G, V35T, E36DN, K122KR, S162A, F171Y, K173T, Q174KN, D177E, V189I, T200A, I202V, Q207E, L210M, F214L, V245Q, T286A, E291D, V292VI, I293V, P294T, S322T, G335D, R356K, M357R, G359S, Q367L, A371V, I375V, A376PS, T386TI, K390R, K395R, A400T, T403M  
C473S C473S None None   K32R, V35T, I135V, A158S, S162A, T165TI, K173T, Q174KN, D177E, T200A, Q207E, R211K, V245Q, K281R, T286A, E291D, V292VI, I293V, P294T, S322T, I326V, G335D, R356K, M357R, G359S, A371V, I375V, A376AV, T377G, K388R, K390R, T403M, E413D  
C475S C475S None None   V35T, E36D, E40D, K49R, V60I, I135L, S162A, K173I, Q174K, D177E, T200A, Q207DGNS, R211K, V245Q, T286A, A288T, E291D, V292I, I293V, P294T, S322T, I326V, G335D, F346Y, R356K, M357R, G359S, I375V, T377V, K390R  
C476S C476S None None   V35T, K49R, V60I, I135V, S162A, E169K, K173A, Q174A, D177E, T200A, Q207E, R211K, V245Q, S251D, T286A, V292I, I293V, P294T, E300EA, S322T, G335D, R356K, M357K, G359S, K366R, T369A, I375V, A376S, V381I, K390R, K395R, E399D, A400T, T403M, E432D, V435I  
C480S C480S None None  K103N K32R, V35T, E40D, V60I, S68SG, I135V, I142V, S162A, K173T, Q174R, D177E, T200A, Q207A, R211K, F214L, V245Q, E248D, Y271H, T286A, E291D, V292I, I293V, E297A, I309IL, V317A, E328D, G335D, M357R, G359S, K366R, T369V, A371V, I375V, A376V, T386P, A400T, W410Y  
C481S C481S None None   V35T, V60I, S68SG, D123E, I135V, S162A, K173AT, Q174K, D177E, I178M, T200A, Q207G, R211K, P243S, V245Q, S251H, K281R, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357R, G359S, A371V, I375V, S379G, V381I, K390R, K395R, A400T, T403M  
C482S C482S None None   V35T, E40D, K49R, V60I, K122R, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, V245T, D250E, S251N, T286A, E291D, V292I, I293V, S322T, G335D, R356K, M357R, G359S, E370A, A371V, I375V, A376S, K390R, K395R, T403M  
C483S C483S None None   V35T, K104R, D123DN, I135V, S162A, K173A, Q174K, D177E, I178M, V189I, T200A, Q207E, P243T, V245Q, A272P, K275R, Q278N, T286A, E291D, V292I, I293V, E297A, S322T, I326V, R356K, M357K, G359S, T369TA, A371V, K374KR, I375V, A376T, K390R, T403M, F416Y, E432D, V435A  
C486S C486S None None   V35T, T39A, V90VI, D121Y, K122E, D123G, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, K275Q, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, T369A, A371V, I375V, T377M, K390R, K395R, T403M, E432D, V435L  
C495S C495S None None   V35I, I135L, S162A, K173S, D177E, V179I, Q207D, R211K, V245Q, E248N, T286A, K287Q, E291D, V292I, I293V, P294T, E312N, G335D, R356K, M357K, G359S, A371V, S379G, I380V, K390R, A400T, E432D  
C497S C497S None None   E6D, K11A, V35T, T39A, I135V, K173I, Q174K, D177E, T200A, Q207K, R211Q, V245Q, D250E, S251D, A272P, V276I, K281R, T286A, E291D, E297A, L310I, G335D, F346Y, R356K, M357V, G359S, A376S, K390R, K395R, A400T, E404D Q91QH, Q151P, Q161H 
C498S C498S None None   V35T, E36AD, E40ED, V60I, K64R, D121HY, K122KE, S162A, K173T, Q174K, D177E, T200A, Q207A, R211K, V245Q, S251N, A272P, T286A, E291D, V292I, I293V, P294T, S322T, G335D, F346L, R356K, M357R, G359S, T369TA, A371V, I375A, T377I, A400T, T403M, E432D, V435A  
C503S C503S None None   V35T, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, I202V, Q207EG, R211K, P243H, V245Q, Y271F, R284K, T286A, E291D, I293V, P294T, S322T, G335D, R356K, M357K, G359S, K366R, A371V, I375V, T377M, K390R, K395KR, T403M, E432D  
C505S C505S None None   V35T, T39AS, I135V, S162A, K173I, Q174K, D177E, T200A, Q207E, V245Q, K277R, T286A, E291D, V292I, I293V, P294T, S322A, G335D, R356K, M357K, G359S, A371V, I375A, A376S, T377V, K390R, K395R, T403M  
C506S C506S None None   V35T, E36ED, T39K, V60I, K122E, D123DN, I135L, S162A, K173T, Q174R, D177E, T200A, Q207E, R211K, V245E, T286A, E291ED, V292I, I293V, P294T, L295M, K311R, S322T, I326V, I329V, G335D, R356K, M357K, G359S, A371V, I375IV, A376S, T386I, K390R, K395KR, T403M, E432D, V435A  
C507S C507S None None   V35T, E40D, K49R, V60I, K122A, S162A, K173T, D177E, T200A, Q207E, V245Q, D250DE, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357R, G359S, V365I, T369V, A371V, V372I, I375V, A376S, S379G, K390R, T403M, E432D, V435M  
C509S C509S None None   V35T, T39S, K122P, I135V, S162A, K173T, Q174EK, D177E, T200A, Q207G, V245Q, E248D, S251I, K277R, T286A, E291D, I293V, E297A, S322A, G335D, R356K, M357K, R358K, G359S, A371V, I375V, A376T, T377M, T386P, K388Q, K390R, Q394R, K395R, A400T, T403M  
C510S C510S None None   V21I, K32KR, V35T, V60I, K122E, T165I, Q174K, D177E, I178M, G196E, T200V, Q207E, R211K, V245Q, D250DE, K277R, L283I, T286A, I293V, E297A, F346H, M357I, R358K, G359S, T377Q, K390R, A400T  
C511S C511S None None   V35T, T39A, E40D, K122R, D123E, I135V, S162A, K173T, Q174KR, D177E, I178IM, T200A, Q207E, R211Q, V245Q, E248EDKN, T286A, E291D, V292I, I293V, P294T, S322A, R356K, M357K, G359S, A371V, I375A, K390R, K395R, A400AT, T403M  
C512S C512S None None   V21I, K32KR, V35I, V60I, I135V, I142V, Q174E, D177E, I178M, T200A, Q207K, R211Q, V245Q, E248D, A272P, K275R, V276I, L283I, T286TA, E291D, V292I, I293V, I329L, Q334R, G335D, F346H, R358K, G359S, T377L, K390R, A400T  
C513S C513S None None   V35T, E36D, T39A, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, I202V, Q207E, L210M, R211K, F214L, P243H, K281R, R284K, T286A, E291D, I293V, P294T, S322T, G335D, R356K, M357R, G359S, T369A, I375V, A376S, T377L, K390R, K395R, A400T, E415X, E432D V245*K 
C514S C514S None None   V35T, E36D, E53D, R83RK, I135V, S162A, K173T, Q174R, D177E, T200A, Q207A, V245K, K277R, T286A, E291D, V292VI, I293V, P294T, S322T, I326V, G335GD, R356RK, M357K, G359S, A371V, I375V, T377TI, K390R, K395R, A400T  
C515S C515S None None   V35T, T39R, K49R, K122E, S162A, K173T, Q174R, D177E, T200A, I202V, Q207E, P243T, V245IT, T286A, E291D, V292I, I293V, P294PT, S322T, G335D, R356K, M357R, G359S, K366R, T369A, A371V, I375V, A376S, K390R, K395R, T403M, T409N  
C517S C517S None None   V35T, E36D, T39L, S68T, V90I, V118I, K122E, D123DN, I135V, S162A, K173T, Q174G, D177E, T200A, Q207E, P243T, V245Q, T286A, E291D, V292I, I293V, P294PT, S322T, I326V, G335D, Y342F, R356K, M357K, G359S, K366R, A371V, I375V, A376AV, T386A, K390R, T403M  
D301T D301T None None   V35T, T39M, I135V, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, P247Q, T286A, E291D, I293V, P294T, S322T, G335D, R356K, M357K, G359S, T369A, A371V, I375V, A376S, T377M, K390R, A400T, T403M  
D303T D303T None None   V35T, K122E, D123N, S162A, K173T, Q174K, D177E, I178M, T200A, Q207D, R211RK, V245Q, E248N, D250E, A272P, K277R, T286A, E291D, V292I, I293V, D324E, Q334P, G335D, F346Y, R356K, M357R, R358G, G359S, K366R, A376S, T386V, K390R, Q394R, A400V, Q428R, K431T  
D304T D304T None None   P4PT, I5V, T7TP, K11T, K20R, V35T, E36A, T39K, K43E, K104R, D121H, K122E, I135T, I142V, S162Y, K173S, Q174QK, D177E, V179I, I202V, Q207E, R211K, F214L, V245Q, E248D, T286A, E291D, V292I, I293V, P294T, I326V, G335D, M357K, G359S, K366R, T369V, A371V, I375V, A376V, A400T, T403M, W410C, E432D, V435M  
D305T D305T None None   K20R, V35T, E36D, T39IN, V60I, K122P, I135V, S162A, Q174E, D177E, T200A, Q207N, V245Q, K277R, T286A, I293V, P294T, S322T, G335D, R356K, M357K, G359S, K366R, A371V, I375V, T377V, K390R, T403M  
D307T D307T None None   V35T, E36D, E53ED, K122E, I135V, S162A, K173I, Q174K, D177E, T200A, Q207E, R211K, F214L, P243PA, V245EK, S251I, K275S, R284K, T286A, E291D, I293V, P294EV, E297K, S322T, G335D, R356K, M357R, G359S, A371V, I375V, A376T, V381I, K390R, A400V, T403M, E415X  
D309T D309T None None   V35T, E36N, T39A, K122E, I135V, S162A, K173A, Q174K, D177E, I178M, Q207E, K223KR, P243T, V245Q, S251SC, K281R, T286A, E291D, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, A376S, T377I, K390R, K395R, A400T, T403M, E432D  
D311T D311T None None   V35T, T39K, K43E, K102R, I135IV, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, T286A, E291D, I293V, P294AT, S322A, I326V, R356K, M357K, R358K, G359S, A371V, I375V, T377LS, K390R, T403M, P412X  
D312T D312T None None  V108VI V35T, I135IV, K173R, Q174E, D177E, T200A, Q207K, R211K, V245Q, E248V, A272P, V276VI, T286A, E291D, V292I, I293V, E297A, Q334P, Q340H, F346HY, G359S, T377L, S379G, K385R, K390R  
D313T D313T None None   V10VA, V35T, E36D, D121H, K122E, I135T, S162A, E169ED, K173AT, Q174KR, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, R358K, G359S, A371V, I375V, T377Q, K390R, T403M, E432D, V435M  
D315T D315T None None   K20R, V35T, K122R, I135V, S162A, K173T, Q174R, D177E, T200A, E203D, Q207E, R211A, V245K, V261I, K277R, Q278N, T286A, E291D, V292I, I293V, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, K390R, T403M, E432D, V435M  
D316T D316T None None   V21I, K32R, V35T, S162A, K173A, Q174K, D177E, I178M, E194EK, G196E, T200A, Q207E, R211K, V245Q, E248N, A272Q, T286A, E291D, V292I, I293V, E297V, G335D, R356K, M357R, G359S, A371V, I375V, T377M, K390R, A400T, E404D  
D317T D317T None None   V21I, V35T, T39K, V60I, W88C, K122E, D123S, K173T, Q174K, D177E, I178M, I195IL, T200A, Q207A, R211E, V245Q, E248D, D250E, A272S, T286A, E291D, V292I, I293V, K311R, I329V, Q334L, F346Y, R356K, M357R, R358G, G359S, T386V, Q394K, A400V, K431T  
D318T D318T None None   V35T, K49R, I50V, V60I, K122KR, D123E, T139K, S162C, K173T, Q174K, D177E, I178IL, T200TA, Q207E, V245Q, K281R, T286A, E291D, V292I, I293V, P294PT, S322AT, I326IV, G335D, R356K, M357K, G359S, K366KR, A371V, I375V, K390R, K395R, T403M, E432D  
D319T D319T None None   V35T, E36D, K49R, I135V, S162A, E169K, K173A, Q174K, D177E, G196E, T200A, Q207K, R211E, V245Q, A272P, K275R, T286A, E291D, V292VI, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375V, T377L, K390R  
D321T D321T None None   V21I, K32R, V35T, V60I, S162A, K173A, Q174K, D177E, I178M, T200A, Q207E, R211K, V245Q, E248N, A272P, T286A, E291D, V292I, I293V, E297V, G335D, R356K, M357R, G359S, T369A, A371T, I375V, A376S, T377I, K390R, A400T, K431T  
D324T D324T None None   V35A, T39A, K104R, K122E, I135V, S162A, K173T, Q174R, D177E, I178M, T200A, Q207G, R211K, V245Q, E248D, S251I, K277R, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357K, G359S, K366R, A371V, I375V, K390R, K395R, T403M  
D325T D325T None None   V35T, T39N, E40D, I135A, S162A, K173KT, Q174N, D177E, I178IV, Q207E, R211K, V245Q, K281KR, T286A, E291D, I293V, P294T, I329V, F346Y, M357V, G359S, A376S  
D326T D326T None None  K103N V35T, E36ED, T39A, E40D, E53D, V90I, S162A, K173I, Q174K, D177E, G196E, T200A, Q207G, R211A, V245M, V276I, Q278E, T286A, V292I, I293V, E297K, S322T, D324E, G335D, R356K, M357K, G359S, T369A, A371V, I375V, A376V, T377TIM, I380V, T386P, K390R, K395R, A400T, T403M, I411M, E432D  
D327T D327T None None   V35T, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, R211E, V245Q, P247A, A272P, T286A, E291D, I293V, S322T, D324E, I326V, G335D, R356K, M357R, G359S, A371V, I375V, A376N, S379C, I382IV, K390R, E399D, W410C, E432D, V435A  
D329T D329T None None   V35T, T39M, D123DN, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, P243H, V245Q, E248V, T286A, E291D, I293V, P294T, S322T, R356K, M357K, G359S, A371V, I375V, T377V, T386A, K390R, T403M, E432D  
D330T D330T None None   K20R, V35K, S162A, K173T, Q174K, D177E, I178IM, V189VI, T200A, Q207E, R211S, V245Q, E248N, S251C, T286A, E291D, I293V, P294T, K311R, S322A, G335D, R356K, M357K, G359S, T369A, A371V, I375A, A376S, T386I, K390R, K395R, T403M, E432D  
D331T D331T None None   V35T, E36D, K49R, K122E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207A, R211D, V245Q, V261I, K281R, T286A, E291D, V292I, I293V, S322T, A327V, G335D, R356K, M357K, G359S, A371V, I375V, K390R, T403M, E432D E169M 
D332T D332T None None   V35T, V90I, S162A, E169Q, K173T, Q174N, D177E, I178M, T200A, Q207K, R211Q, P243T, V245H, A272S, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, T369A, A371V, I375A, K390R, K395R, A400AT, T403TM, I411X, E432D  
D334T D334T None None   V35T, E36N, K102R, K122Q, I135V, E138A, S162A, K173T, Q174K, D177E, V189I, T200A, I202V, Q207E, F214L, P243H, V245Q, T286A, E291D, V292I, I293V, P294T, K311KR, S322T, I329IV, Q334R, G335E, R356K, M357K, R358G, G359S, Q367E, E370K, A371V, I375V, T377M, V381I, K390R, K395R, T403M, E432D  
D335T D335T None None   K20R, V21I, V35T, T39K, E40D, V60I, K104R, D121Y, K122E, I135V, T165I, K173T, Q174K, D177E, T200A, Q207E, R211N, V245Q, E248S, D250E, A272P, I274V, Q278H, T286A, E291D, V292I, I293V, P294T, E297A, L301M, I329V, Q334L, G335D, F346H, R356K, M357R, R358G, G359S, A371V, I375V, S379G, T386I, A400V, K431T, V435P  
D337T D337T None None   V35T, V60I, K104R, K122E, D123N, I135RT, F171Y, K173A, Q174K, T200A, Q207G, R211K, I244V, V245Q, E248D, D250E, S251N, A272P, T286A, E291D, V292I, I293V, I329V, Q334L, G335D, F346Y, R356K, M357K, R358G, G359S, A371V, A376S, T386V, Q394R, A400V, V423X, Q428R, K431T, E432D, V435P  
D338T D338T None None   V35T, K122E, D123S, I135V, S162A, K173G, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q, K277R, L283I, T286A, E291D, V292I, I293V, S322T, G335D, R356K, M357K, G359S, A371V, I375V, S379G, K385R, K390R, A400T, T403M, V435A  
D339T D339T None None   V35T, E36D, T39A, E40D, K49R, I135L, S162A, K173T, Q174QK, D177E, T200A, Q207E, R211K, V245Q, V276I, K277KR, T286A, E291D, V292I, I293V, I326V, G335D, R356K, M357K, G359S, K366KR, T369V, A371V, I375V, A376T, T377I, K390R, A400T, T403TM, E432D