<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Kousiappa (2009)
Title Near full-length genetic analysis of HIV sequences derived from Cyprus: evidence of a highly polyphyletic and evolving infection.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 77
NumPts 77
Subtype B, A, C, CRF02_AG, D, F, CRF04_cpx, CRF01_AE

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
CY018 CY018 Unknown Unknown A62V, T69~, L74V, Q151M K103N, V108I, Y181C, G190A S68G, V90I, K102Q, D123E, T165I, Q174K, D177E, D192N, I202V, F214L, H221Y, V245M, T286A, E297K, I326V, E328K, Q334L, M357T, V381I, T386I, K388R, A400L, K451R, H483Y I63V, Q182H 
CY020 CY020 Unknown Unknown   D123E, I135T, K166R, D177E, I178L, F214L, V245M, K277R, T286A, A288S, I293V, E297A, M357T, A376T, T386I, A400T, K431T, V435L, T473A, H483Y, L491S, L517V, Q520H, K527N  
CY021 CY021 Unknown Unknown M184V A98G, G190S K11T, V35T, E36D, V90I, K122E, D123N, A158S, K173L, Q174K, D177E, T200I, Q207A, R211S, I244V, V245T, E248D, A272P, T286A, E291D, V292I, I293V, P294T, D324E, I326V, G335D, R356K, M357K, R358G, G359S, E370A, A371V, I375V, V381I, K390R, E399D, K431T, V467I, T470N, D471E, Q480H, L491S, K512R, L517I, S519N, Q520K, Q524K, K527E, K530R, A534S, A554T  
CY022 CY022 Unknown Unknown   V35T, E36D, T39K, V60I, D123E, I135T, K173L, Q174K, D177E, V179I, T200V, Q207A, R211S, V245K, D250E, K277R, T286A, E291D, V292I, I293V, P294T, E312D, I326V, G335D, M357K, G359S, A371V, I375V, T377M, K385R, A400T, W402G, T403M, E404D, E432D, V435I, A437V, E449D, T450S, L452I, D471E, Q480H, H483Y, L491P, Q509T, K512R, S519N, Q524K, K527G, E529D, A534S, A538P, A554S  
CY023 CY023 Unknown Unknown   V35T, T39N, V60I, L80X, D123E, I135T, K173I, Q174K, D177E, V179I, T200V, Q207A, R211S, V245K, D250E, K277R, T286A, E291D, V292I, I293V, P294T, E312D, I326V, G335D, M357K, G359S, T369A, A371V, I375V, T377M, K385R, A400T, T403M, E404D, E432D, V435A, E449D, T450S, L452I, D471E, Q480H, H483Y, L491P, Q509T, K512R, S519N, Q524K, K527G, E529D, V531I, A534S, A554S  
CY028 CY028 Unknown Unknown   V35I, K101R, K122Q, F171Y, D177E, I178V, T200I, F214L, A272P, I293V, Q334D, K350R, A360T, I375V, A376S, K385R, A400T, N447S, L491S, Q520H, K527N, L533M, V548I, A554S  
CY029 CY029 Unknown Unknown   V35T, D121H, K122E, I135V, S162A, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, V245Q, V254I, T286A, E291D, V292I, P294T, E312Q, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, K390R, K395R, E432D, V435L, A437V, D471E, Q480H, H483Y, L491S, K512R, L517F, V518F, S519N, Q524K, E529D, A534S, A538S, A554N  
CY030 CY030 Unknown Unknown   K82R, I135L, S162C, T200I, R211K, A272P, A288S, I293V, E297D, I329L, G333E, R356K, A360V, V365I, A376S, T377L, S379C, K385R, K390R, E399D, T403A, K454R, H483N, V531I, I556V, K558R  
CY031 CY031 Unknown Unknown   D86E, K104Q, D123E, I135V, S162C, D177E, A272P, T286A, D460N, S468P, L491A I274F, V365A 
CY032 CY032 Unknown Unknown   K20R, V35I, S68G, K122V, D123N, K166R, D177E, G196E, T200I, E204K, Q207H, R211G, F214L, V245I, A272P, K277R, G333E, R356K, M357T, A360T, A400T, V435L, L452M, V466A, S468P, K512R, S519N, D549N, V559I  
CY033 CY033 Unknown Unknown   V118I, K122E, I135T, D177E, V189I, G196E, F214L, V245I, K277R, T286A, A288S, I293V, E297A, P321S, M357T, A376V, T386I, A400T, K527N, D549N, V552G  
CY035 CY035 Unknown Unknown   V35I, I135L, S162G, V245I, Q278H, T286A, I293V, E297A, I329L, E344D, P345Q, F346Y, A376V, T386I, A400T, V435I, T450N, K454N, S468P, T477A, L491S, L517I, K527I, I556V  
CY036 CY036 Unknown Unknown   D123E, I135T, D177E, F214L, V245L, K277R, T286A, A288S, I293V, E297A, M357T, T386I, A400I, V435L, Q520H, K527N, A554T  
CY037 CY037 Unknown Unknown   D123E, E169D, D177E, T200A, I202V, A272P, Q334L, S379G, T386I, V435E, R461K, L469I, H483Y, L491S, S519N, Q524K, K527N, V531I  
CY038 CY038 Unknown Unknown   E169D, D177E, T200A, A272P, K277R, K311R, S379G, T386V, H483Y, L491S, S519N, Q524K, K527N, V531I  
CY040 CY040 Unknown Unknown D67G, K70T, M184V, T215I, K219E  S3I, K20R, V35I, E36A, T39E, E40D, E53D, S68G, K122E, D123S, I135L, K173A, Q174K, V179I, G196T, T200A, Q207A, V245Q, A272S, K275Q, T286A, A288G, E291D, V292I, I293V, V317A, S322A, I329V, Q334L, R356K, G359T, T369V, T386I, K390R, Q394L, A400T, T403S, E404D, V435P, A446S, L452T, S468P, D471E, T477A, H483Q, L491S, K527N, K530R, V531I, A554S F61L 
CY048 CY048 Unknown Unknown   V35T, T39M, D121H, K122E, D123E, I135T, A158S, S162A, K173T, Q174K, D177E, T200A, Q207G, R211K, V245Q, K281R, L283I, T286A, E291D, V292I, I293V, P294T, S322P, I326V, G335D, R356K, M357R, R358G, G359S, E370Q, A371V, I375V, T377V, K390R, T403M, E432D, V435I, D471E, Q480H, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554N  
CY051 CY051 Unknown Unknown   V35T, V60I, I135T, E169D, K173S, Q174K, D177E, I178L, V179I, I195L, T200A, Q207A, R211S, V245Q, D250E, K277R, K281R, T286A, E291D, V292I, I293V, P294T, E297K, E312D, A327V, G335D, M357K, G359S, T369A, A371V, I375V, A376V, T377M, A400T, W402G, E404D, E432D, D471E, Q480H, L491S, K512S, L517I, S519N, Q524K, K527G, E529D, A534S, A554S, V559I  
CY055 CY055 Unknown Unknown   K20R, S48T, I135T, T165I, Q207E, R211K, V245K, A272P, K277R, L283I, A288G, I293V, R307K, S322T, I329L, R356K, A360T, T377Q, T386I, E399D, T403I, E404D, K465Q, T470K, K476R, T477A, H483Y, Q507P, V531I, A554T, K558R E344K 
CY056 CY056 Unknown Unknown T215F K101E, G190R V60I, D177G, T200I, E203K, R211K, E248V, D250E, A272S, T286A, I293V, P294T, I326V, A376S, T377M, K390R, A400T, D460N, E492Q, K512Q, L517I, S519N  
CY057 CY057 Unknown Unknown   K11T, V35T, T39K, E40D, P55S, K102R, K122E, D123S, A158S, K173L, Q174K, N175H, D177E, Q207A, R211S, V245M, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294T, D324E, I326V, Q334P, R356K, M357K, R358G, G359S, Q367E, E370A, A371V, I375V, S379G, V381I, K390R, T403M, L452I, S468P, D471E, Q480H, L491S, K512R, L517I, S519N, Q520R, Q524K, K527E, K530R, A534S, A554Y, K558R  
CY058 CY058 Unknown Unknown   K11T, T27A, E28K, V35T, S68G, K122E, D123S, A158S, K173L, Q174K, D177E, Q207A, R211S, V245T, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294T, D324E, I326V, R356K, M357K, R358G, G359S, E370A, A371V, I375V, S379G, V381I, K390R, T403M, L452I, S468P, D471E, Q480H, L491S, K512R, L517I, S519N, Q520R, Q524K, K527E, K530R, A534S, A554Y, K558R P1A, W24G, N57D, E79K 
CY063 CY063 Unknown Unknown M184V  V35T, E40D, V60I, W88C, K122E, D123N, I135T, D177E, Q207E, R211K, V245Q, D250E, A272S, K277R, T286A, V292I, I293V, E297K, P321Q, E328K, I329L, G335D, R356K, G359S, T377M, K390R, A400T, V435T, E449Q, S468P, H483N, Q547K, A554S  
CY064 CY064 Unknown Unknown   V35T, T39A, E40D, K43R, K101Q, D123N, I135T, E138A, T139L, E169D, K173S, Q174K, D177E, V179I, T200A, E203K, Q207D, R211S, F214L, V245Q, A272P, K281R, E291D, I293V, P294T, E312D, G335D, R356K, M357R, R358K, G359T, A360T, A371V, V372M, I375V, A376V, T377L, V381I, I382V, K388R, A400T, T403R, E404D, E432D, V435I, D471E, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527E, A534S, A554S, K558R  
CY065 CY065 Unknown Unknown   V35I, K122E, I135T, I142V, R211K, I293V, K311R, Q334L, G335C, M357V, T386I, E399D, A400L, E438D, L452I, V466D, L491S, K512Q, S519N, V531I, D549N G99E 
CY067 CY067 Unknown Unknown   D121Y, I135M, S162Y, D177G, T200A, V245M, T286A, I293V, E297V, I326V, M357V, K431R, A446S, L452V, H483Y, K512Q, K530R G112S 
CY068 CY068 Unknown Unknown   V35I, D121H, K122E, I135T, D177E, T200I, D250E, A272P, K277R, F346C, A376T, K390R, A400T, V435I, D460N, I482V, H483Y, L491S, K512R, S519N, K558R G99E 
CY069 CY069 Unknown Unknown M184V K103N, P225H, M230L V35T, E36A, T39E, S48T, E53D, K122E, D123N, K173A, D177E, G196K, T200A, Q207A, H221Y, V245Q, A272P, K275R, K277R, T286A, E291D, V292I, I293V, P294T, G335D, R356K, G359T, T369A, I375V, T377M, K390R, K395R, T397I, E404D, I434M, V435A, V467I, S468C, D471E, T477A, H483Q, L491S, S519N, K527N, K530R, A534S, A554S  
CY070 CY070 Unknown Unknown   T39I, V118I, I135T, T200I, E204A, Q207E, R211K, F214L, V245M, K277R, T286A, M357T, T386I, A400T  
CY072 CY072 Unknown Unknown   S3I, V35L, D123E, D177Q, I202V, F214L, K277R, T286A, A288S, I293V, P294T, E297A, V317A, I326V, Q334L, M357T, A376V, T386M, A400I, V467I, S519N, K527S, V531I N54D 
CY074 CY074 Unknown Unknown   K122E, Q207A, R211K, V245Q, K277R, R284K, T286A, I293V, S322T, M357T, K390R, L452S, K454E, V466I, S468P, D471Y, H483Y, A538V, H539P, R557K  
CY075 CY075 Unknown Unknown   K20R, I135T, Q207E, R211K, V245K, A272P, V276I, K277R, L283I, I293V, S322T, I329L, R356K, A360T, T377Q, T386I, E399D, T403I, E404D, K465Q, T470K, T477A, H483Y, L491V, V531I, A554T, V559I  
CY077 CY077 Unknown Unknown K70R, M184V, N348I K103N D123E, I135T, D177E, F214L, V245T, K277R, T286A, A288S, I293V, E297A, M357T, T386I, A400T, V435L, K451R, L491V, K527S  
CY081 CY081 Unknown Unknown D67N, K70R, M184V, T215F, K219E K101E, K103N E28K, V35T, T39M, V60I, P119S, K122P, D123E, I135S, S162C, K173S, Q174K, D177E, I178L, T200A, Q207E, V245Q, A272P, T286A, E291D, V292I, I293V, E297T, V317A, P345L, F346H, M357T, G359S, K366R, T377M, S379C, K390R, E399D, A400T, K431T, E432D, V435A, L452Q, V466I, T470S, D471E, L491S, L503I, K512R, E516D, S519N, Q520L, K527Q, E529D, A534S, A554N R83S, T84S, D86V, P95A, L100S, K104I, V108L, F124S, T128I, L205V 
CY082 CY082 Unknown Unknown K70R, K219Q  D123E, I135T, D177E, F214L, L228R, V245M, K277R, T286A, A288S, I293V, E297A, K311R, M357T, A371V, A376T, K388R, A400I, V466A, L491S, E514D, K527N, A534T  
CY087 CY087 Unknown Unknown  K101E K20R, V35I, K82R, P97X, K104R, V106I, I135T, K173E, Q207A, V245K, A272P, K275R, R284K, T286A, I293V, S322A, I326L, M357T, T369V, K390R, V466I, S468P, Q480H, K512R, A554T, K558R R83D, T84R, Q85K, D86L, F87Y, E89I, V90Q, Q91E, L92Q, G93M, P95Q, H96Y, A98R, G99R, L100H, K102L, K103A, S105K 
CY088 CY088 Unknown Unknown   K20R, K122E, D123E, I142V, Q174K, D177E, I178L, F214L, T286A, A288S, V292I, E297A, P345Q, M357T, I380L, V381I, K385R, T386I, K388I, K390R, E399D, A400I, H483Q, L491S, A554S  
CY089 CY089 Unknown Unknown   K20R, A98S, D123E, I142V, Q174K, D177E, I178L, F214L, K277R, T286A, A288S, E297A, M357T, I380L, V381I, T386I, K390R, E399D, A400I, H483Q, L491S, Q520L  
CY090 CY090 Unknown Unknown D67N  V21I, K32R, V35T, E44K, V60I, D86N, D123E, I135T, E138A, S162C, K173T, Q174K, D177E, D192N, E194K, T200A, E203K, Q207T, R211K, V245Q, E248D, A272P, K275R, V276I, Q278H, K281R, T286A, E291D, V292I, I293V, P294T, E300K, Q334H, R356K, M357I, G359S, T362P, V365I, A376S, K390R, E399D, A400I, W402G, K431T, V435A, R448I, L452E, D471E, H483Y, L491S, Q509H, S519N, E529D, A534S, V548I, I556V G45R, R72K, D113N, A129T, D185N, D256N, Q475P 
CY092 CY092 Unknown Unknown  V179D V8G, K32T, V60I, S68G, K102R, D121C, K122E, I135K, K166R, G196D, T200A, V245M, S251I, A272P, V276I, T286A, I293V, K311R, S322T, E344D, P345Q, M357S, K366R, K390R, K431T, V435I, V466I, S468P, L491S, K527I, A554S K49Y, K73L 
CY093 CY093 Unknown Unknown   D123E, I135T, K166R, D177E, F214L, V245M, E248D, K275R, K277G, E291K, E297N, E298*, L301I, E308G, H315Y, V317G, Q330L, K331E, Q343R, M357T, A376T, T386I, A400I, T473A, K527H V276G, T286D, A288L, E300N, E305K, N306K, V314R, Q332M 
CY096 CY096 Unknown Unknown   V35I, I135L, S162C, T200A, V245I, V276I, Q278H, I293V, E297A, I329L, E344D, P345T, M357I, A360T, T386I, A400T, V435I, G453*, K454N, S468P, L491S, S513N, L517I, Q520L, K527I I411S 
CY097 CY097 Unknown Unknown   D123E, I142V, K166R, D177E, F214L, K277R, T286A, A288S, E297A, M357T, I380L, T386I, A400I, K451R, L491S, K527R, A554T  
CY100 CY100 Unknown Unknown   E169D, D177E, V179I, G196E, R211K, V292I, I293V, E297A, A327V, I329V, V365I, A376T, S379C, V381I, K395R, E399D, L452I, S468P, L469I, L491S  
CY106 CY106 Unknown Unknown   V35T, V60I, K122E, D123S, K173L, Q174K, D177E, V179I, T200A, Q207A, R211S, V245K, D250E, A272P, K281R, T286A, E291D, V292I, I293V, P294T, G335D, P345S, M357K, G359S, T369A, A371V, I375V, T377M, K388N, A400T, T403R, E404D, K431T, E432D, V435I, D471E, Q480H, L491S, E516D, S519N, Q524M, K527G, E529D, A534S, I556V, V559I  
CY107 CY107 Unknown Unknown  K103N, K238T S162C, E169D, D177G, T200A, R211K, A272P, K281R, T286A, E291D, V292I, I293V, P294T, G335D, P345S, M357K, G359S, T369A, A371V, I375V, T377M, K388N, A400T, T403R, E404D, K431T, E432D, V435I, D471E, Q480H, L491S, E516D, S519N, Q524M, K527G, E529D, A534S, I556V, V559I  
CY110 CY110 Unknown Unknown   K32Q, V35I, I50V, K122E, I135K, E169D, Q207K, R211K, A272P, K277R, E328K, I329V, G333E, Q334H, T386I, K390R, A400S P140T, E305K 
CY111 CY111 Unknown Unknown   K11A, V35T, K122E, D123N, I135T, I142V, E169D, K173T, Q174K, D177E, T200A, Q207A, E248D, T286A, V292I, I293V, P294T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, A376T, T377M, E399D, A400T, T403A, E432D, V435E, A455S, R461K, D471E, T477A, Q480H, H483Y, K512R, S519N, Q524K, K527E, A534S, A554S  
CY112 CY112 Unknown Unknown   K11A, V35T, K122E, D123N, I135T, I142V, E169D, K173T, Q174K, D177E, T200A, Q207A, E248N, T286A, V292I, I293V, P294T, A327V, G335D, R356K, M357K, G359S, T369A, A371V, I375V, T377M, E399D, A400T, T403V, E432D, A455S, R461K, D471E, T477A, Q480H, H483Y, K512R, S519N, Q524K, K527E, A534S, A554S  
CY113 CY113 Unknown Unknown   V35T, I135T, Q278H, K281R, I293V, I326V, K390R, W414G, V435E, D460N, L503I, S519N, A554T, K558R  
CY120 CY120 Unknown Unknown   K22R, D123E, I135T, K166R, D177E, R211K, F214L, A272P, K277R, I293V, E297A, K311R, Q334L, R358K, K366R, T377N, K390R, T403M, E404D, K431T, V466A, H483Y, Q509K, S519N, I526V, K527Q, A554S  
CY121 CY121 Unknown Unknown   V35T, V60I, D121H, K122E, I135T, S162C, E169D, K173S, Q174K, D177E, I178L, V179I, T200A, Q207A, R211S, V245Q, D250E, K277R, T286A, E291D, V292I, I293V, P294T, E312D, G335D, M357K, G359S, T369A, E370K, A371V, I375V, T377M, E399D, A400T, E404D, E432D, V435L, D471E, Q480H, L491S, K512S, L517I, S519N, Q524K, K527E, E529D, A534S, A554S, V559I  
CY122 CY122 Unknown Unknown   K11Q, S68G, S162C, T200A, R211K, K277R, A288S, I293V, E312Q, I326V, Q334L, V365I, A376S, T403M, V435A, K451R, L452A, K527N, K530R  
CY124 CY124 Unknown Unknown D67N, K219Q  K20R, D86E, S162C, I195T, G196E, R199K, E203V, H221Y, A272P, V292I, I293V, I329V, S379G, D460N, R461S, V467I, S468P, L491V, S519N  
CY130 CY130 Unknown Unknown   K122E, E169D, N175H, R211K, A272P, K281R, P294H, E297Q, E328D, A376S, T377Q, T386I, A400I, F440Y, L469F, T470S, T477A, L491T, Q524H, A554T  
CY131 CY131 Unknown Unknown   D123E, S162C, Q174H, D177E, R211K, T286A, M357T, E399D, T403M, E413D, I482V, L491S, A502V, K512Q, V531I, A554N  
CY132 CY132 Unknown Unknown   K102Q, D123E, I135T, D177E, F214L, V245M, T286A, M357T, A376T, T386I, A400I  
CY137 CY137 Unknown Unknown   K22R, I135T, R211K, F214L, V245M, V292I, I293V, E297A, K311R, Q334L, A360T, T377N, K390R, A400T, T403M, E404D, K431T, V466A, H483Y, Q509K, S519N, K527Q  
CY140 CY140 Unknown Unknown   V35T, V60I, K64R, K122E, D123N, I135T, E138A, I142T, K173L, Q174K, D177E, I178M, V179I, Q207A, R211S, V245K, D250E, A272P, K281R, T286A, E291D, V292I, I293V, P294T, E297K, E312D, G335D, M357R, G359S, T369A, A371V, I375V, A376V, T377L, Q394H, A400T, T403M, E404D, E432D, V435I, D471E, Q480H, L491S, K512R, S519N, Q524G, K527G, E529D, A534S, A554S, V559I  
CY141 CY141 Unknown Unknown Y115F  K82R, W88R, K102R, K104S, T107P, K122E, D123G, T131P, Y146S, T165P, I167F, E169D, F171L, R172G, K173N, Q174H, N175H, T200A, R211K, A272P, K277R, E297Q, E328D, K366R, A376S, T377Q, T386I, A400I, F440Y, L469F, T470P, L491A, A554T T84L, Q91H, D110E, P133L, N136T, T139P, W153R 
CY142 CY142 Unknown Unknown   V35I, V106I, D123E, E169K, K173E, I178L, G196E, R211S, F214L, K277R, I293V, E297K, G333E, R356K, M357I, A376S, T377L, K390R, E404D, V435I, D460N, R461K, S519N, Q524E  
CY149 CY149 Unknown Unknown  K103N S48T, K102Q, K122E, I135T, E194N, R211K, A272P, P294T, Q334R, F346Y, K390R, T397A, E404D, P433L, V435E, A446S, E449D, D460N, L469I, T470A, H483Y, L491T, Q524E  
CY150 CY150 Unknown Unknown  P225H K20R, T39A, R83K, K102Q, S162Y, T200I, D250E, A272P, T286A, E297K, V314I, G333E, R356G, K390R, W414*, T419I, P420L, D460N, R461K, V467I, L469I, S519N, A554N G543R, G555R 
CY153 CY153 Unknown Unknown   V35A, T39A, V60I, K122E, D123S, I135T, T139A, S162C, K173S, Q174K, D177E, Q207A, R211S, V245E, D250E, K281R, T286A, E291D, V292I, I293V, P294T, G335D, A355T, M357R, G359S, T369V, A371V, I375V, A376S, T377M, K388N, K390R, A400I, E404D, E432D, V467I, D471E, Q480H, L491S, K512R, S519N, Q524K, K527G, E529D, A534S, A554S, I556V, V559I  
CY154 CY154 Unknown Unknown   E6K, K11T, V35T, T39K, K122E, I142V, S162A, K173S, D177E, T200A, Q207D, V245Q, A272P, T286A, I293V, E312N, D320N, I326V, G335D, M357R, G359S, A371V, I375V, A376T, V381I, T403M, E432D, V435I, A446S, T470N, D471E, Q480H, H483Y, L491P, K512R, S519N, Q524E, V531I, A534S, A554S E29K, R78K, E305K 
CY158 CY158 Unknown Unknown   V35T, E36D, T39S, I135V, S162A, F171Y, K173T, Q174N, D177E, I178M, T200A, Q207A, R211S, V245Q, D250E, K275Q, K277R, T286A, E291D, I293V, E312D, S322T, I326V, G335D, R356K, M357R, G359S, T369A, I375V, K390R, K395R, T403M, E432D, D471E, Q480H, L491P, K512R, S515A, S519N, Q524K, K527E, E529D, A534S, A554S  
CY163 CY163 Unknown Unknown   V35T, E40D, K49R, K122E, I135T, S162C, R172K, D177E, I178L, T200A, E204K, Q207E, F214L, V245T, D250E, S251N, A272P, K277R, T286A, V292I, I293V, E328K, G335S, Y339W, R356K, T377I, K390R, T403M, V435I, A446S, R448I, S468P, L469F, H483N, L491P, Q520L, A554R  
CY164 CY164 Unknown Unknown   K20R, V35T, K49R, V60I, D123E, I135T, E169D, K173S, D177E, I178L, V179I, T200A, Q207A, R211S, V245Q, D250E, K277R, T286A, E291D, V292I, I293V, P294T, E312D, A327V, G335D, M357K, G359S, T369A, A371V, I375V, A376V, T377M, E399D, A400T, E404D, E432D, D471E, Q480H, L491S, K512S, L517I, S519N, Q520L, K527G, E529D, A534S, A554S, V559I  
CY165 CY165 Unknown Unknown M41L, A62V, L74V, M184V, L210W, T215Y, K219N L100I, K103N K43E, E44A, A98S, K122E, D123E, I135T, D177E, G196E, H208Y, R211K, L228K, T286A, A288S, E297A, M357T, A360I, A376S, T386I, K388R, E399D, A400T, K451N, H483Q, L491S, K527N  
CY166 CY166 Unknown Unknown   V35T, E36A, T39E, S48T, K122E, D123N, I142V, K166R, K173A, D177N, T200E, Q207R, R211K, V245Q, D250E, A272P, K277R, V292I, I293V, E297A, Q334E, G335D, R356K, M357R, G359T, E370D, T377M, K390R, A400T, E404D, I434L, V435A, A437I, L452M, K454R, V467I, S468T, D471E, H483N, L491S, E492Q, K512T, L517I, S519N, A534S, A554S  
CY168 CY168 Unknown Unknown   I50V, E53D, D123E, S162C, I178L, V179I, T200S, V245M, A272P, K277R, I293V, E297A, I329V, G333E, T377Q, T386I, K390R, A400T, T403M, K431T, V435A, R461K, V467I, T470M, L517I, S519N  
CY171 CY171 Unknown Unknown   K11A, V35T, E36D, T39N, E40D, V60I, K122E, D123S, I135T, K173L, Q174K, D177E, T200I, Q207A, R211S, V245I, E248D, A272P, T286A, E291D, V292I, I293V, P294T, I326V, R356K, M357K, R358G, G359S, E370A, A371V, I375V, K390R, T403M, L452I, S468P, D471E, Q480H, L491S, K512S, S515T, L517I, S519N, Q520K, Q524K, K527E, K530R, A534S, A554N, K558R  
CY173 CY173 Unknown Unknown   K11T, K20R, V35T, E36D, T39K, K122E, D123S, I135T, S162C, K173L, Q174K, D177E, T200I, Q207A, R211S, V245M, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294T, I326V, G335D, R356K, M357K, R358G, G359S, E370A, A371V, I375V, T377K, I382V, K390R, T403M, L452I, S468P, D471E, Q480H, L491S, K512R, L517I, S519N, Q520K, Q524K, K527E, K530R, A534S, A554H, K558R  
CY176 CY176 Unknown Unknown   V35T, T39E, W88L, K122E, D123S, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245K, D250E, A272P, K277R, E291D, I293V, P294S, Q334H, G335D, R356K, G359T, V365I, A376S, T377M, K390R, A400T, E404D, E413D, K451R, L452I, R463K, V466I, V467I, D471E, H483Q, L491S, A508G, E516D, S519N, K527R, K530R, A534S, A554K  
CY178 CY178 Unknown Unknown   S3R, K11T, K20R, V35T, E36D, T39K, K122E, D123S, I135T, S162C, T165I, K173L, Q174K, D177E, T200I, Q207A, R211S, V245M, E248D, K281R, T286A, E291D, V292I, I293V, P294T, E312N, G335D, M357K, G359S, T369A, A371V, I375V, A376V, T377L, K390R, A400T, T403V, E404D, E432D, R461K, S468T, D471E, Q480H, H483Y, L491S, I505V, K512R, S519N, Q524K, K527G, E529D, A534S, A554S, V559I F77V, N265D 
CY179 CY179 Unknown Unknown  K103N, Y181C, G190A E6D, V35T, T39K, K43E, K102Q, D123E, T165I, Q174K, D177E, Q207H, V245E, K275Q, V276I, T286A, E291D, V292I, I293V, P294T, E312T, P321S, D324E, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K395R, A400T, E432D, N447S, D460N, S468T, D471E, Q480H, L491P, K512R, L517I, S519N, Q524E, A534S, A554S W266R 
CY180 CY180 Unknown Unknown   K122E, S134N, S162C, E169D, N175H, R211K, K277R, T286A, V292I, T296S, E297K, G333E, G335S, R356K, M357R, A360T, A376V, T386I, K390R, A400T, K431R, V435E, D460N, S468H, H483Q, L484I, G504*, Q520L, A554T, K558R