<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Rey (2009)
Title High rate of early virological failure with the once-daily tenofovir/lamivudine/nevirapine combination in naive HIV-1-infected patients.
Citation AAC
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 22
NumPts 9
Subtype B, A, C, G

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
1 1bl None None T215C K101E K49R, K103R, I135K, I180V, Q197K, I202V, R211K, V245T  
  1w4 TDF, 3TC NVP T215C K101E, G190GA K49R, K82KR, K103R, I135K, I180V, Q197K, I202V, R211K, V245T  
  1w12 TDF, 3TC NVP K65R, M184MI, T215C K101E, Y181YC, G190A K49R, K82KR, K103R, I135K, I180V, Q197K, I202V, R211K, V245T  
10 10bl None None   T39KN, K43E, K102KQ, K122E, D123S, S162Y, K173LS, D177E, V179I, Q207A, R211K, V245Q  
  10w36 AZT, 3TC NVP   T39K, K43E, V90VI, K122E, D123S, S162HY, K173LS, D177E, V179I, Q207A, R211K, V245Q  
2 2bl None None   R83K, T200A, R211K  
  2w4 TDF, 3TC NVP M184MIV V179VD, Y181YC, G190GA, F227FL R83K, T200A, R211K  
3 3bl None None   K122E, S162C, T200A, E204EAD, Q207N, R211RK  
  3w4 None None  Y181YC K43KR, K122E, S162SC, T200A, E204ED, Q207N, R211RK, H221HY  
  3w12 TDF, 3TC NVP K65R K103N, Y181C, G190GA T39TKN, K122E, S162SC, T200A, E204EA, Q207NT, R211RK  
4 4w4 TDF, 3TC NVP  Y181C D123E, K166R, D177E, R211K, V245DE  
  4w12 TDF, 3TC NVP A62AV, K65KR Y181YC R83RK, D123E, K166R, D177E, R211K, V245E  
5 5bl None None   V60I, K122E, D123NS, K173IV, Q174K, D177E, T200A, Q207E, R211A, V245Q  
  5w4 TDF, 3TC NVP   V60I, K122E, D123NS, K173IV, Q174K, D177E, T200A, Q207E, R211A, V245Q  
  5w12 TDF, 3TC NVP M184I V108VI, Y181C V60I, K122E, D123DN, I135M, K173I, Q174K, D177E, T200A, Q207E, R211A, V245Q  
6 6bl None None   K101Q, K122E, D123AT, S162A, V245VE  
  6w12 TDF, 3TC NVP K65R Y181YC, G190A K101Q, K122E, D123T, S162A  
8 8bl None None  V179D T39E, S48T, K122E, D123S, K173T, Q174K, T200A, Q207E, F214L, L228LQ, K238R, V245Q  
  8w4 TDF, 3TC NVP  V179D T39E, S48T, K122E, D123S, K173T, Q174K, T200A, Q207E, F214L, K238R, V245Q  
  8w12 TDF, 3TC NVP K65R V179D, G190A T39E, S48T, K122E, D123G, K173T, Q174K, T200A, Q207E, F214L, L228Q, K238R, V245Q  
9 9bl None None   T39N, D121DY, K122E, D123G, E169ED, K173A, Q174K, D177E, G196E, Q207A, R211S, V245Q  
  9w24 TDF, 3TC NVP K65R Y181C, G190A T39N, K122E, D123G, E169D, K173A, Q174K, D177E, G196E, Q207A, R211S, V245Q G51GR, G213GR 

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