<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Fish (2010)
Title Natural polymorphisms of integrase among HIV type 1-infected south African patients.
Citation ARHR
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 73
NumPts 73
Subtype C, A, G


Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
FV09 05ZAFV09 None    K7R, D25E, V31I, L45Q, I84M, L101I, T112A, T124S, T125A, K136Q, R187K, K188R, V201I, T206S, K211Q, T218I, L234I, D278A R284G, D288N 
FV10 05ZAFV10 None    D25E, V31I, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, K215N, T218I, L234I, A265V, D278A S283G 
FV11 05ZAFV11 None    D25E, K34R, I72V, I84M, L101I, T112V, T124S, T125P, K136Q, D167E, V201I, L234I, D270E, D278A S283G 
FV13 05ZAFV13 None    S17N, D25E, V31I, M50I, I72V, F100Y, L101I, K111T, T112V, T124A, T125A, K136Q, D167E, V201I, T218I, L234I, D278A S283G 
FV14 05ZAFV14 None    D25E, V31I, I72V, L101I, T112V, K136Q, D167E, V201I, T218I, L234I, D279G S283G 
FV15 05ZAFV15 None    E11D, D25E, V31I, I84M, L101I, T112V, G134D, K136Q, K156R, D167E, V201I, L234I, R269K, D278A V281M, S283G 
FV2 05ZAFV2 None    D25E, V31I, M50T, I72V, V77I, I84M, P90T, L101I, T112V, T124N, T125A, K136Q, D167E, V201I, L234I, R269K, D278A S283D 
FV20 05ZAFV20 None    D25E, V31I, M50T, F100Y, L101I, G106A, T112I, T124A, K136Q, G163A, V201I, T218L, L234I, D278A S283G 
FV22 05ZAFV22 None    K14R, D25E, V31I, L101I, T112V, T124S, K136Q, V201I, N222T, R224Q, L234I, R269K, D270N, D278A S283G 
FV23 05ZAFV23 None    S24N, D25E, I72T, F100Y, L101I, T112V, T125A, K136Q, V201I, T218I, L234I, D278A  
FV25 05ZAFV25 None   T97A E11D, V31I, M50I, L74I, L101V, T112V, T124A, T125A, V126F, G134D, K136Q, D167E, V201I, L234I, D278A S283G 
FV26 05ZAFV26 None    K14R, D25E, V31I, I84M, F100Y, L101I, T112V, T124N, T125A, K136Q, G163E, V201I, K215N, L234I, S255G, R269K, D278A S283G 
FV27 05ZAFV27 None    E10D, V31I, L45I, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, S255G, R269K, D278A S283G 
FV29 05ZAFV29 None    S17N, D25E, V31I, I84M, L101I, T112I, T124A, T125V, K136Q, V165I, V201I, T206S, T218I, L234I, A265V, R269K, D278A S283G 
FV3 05ZAFV3 None    D25E, L101I, T112V, T124A, T125A, K136Q, Q177L, V201I, T218I, L234I, A265V, R269K, D278A S283G 
FV30 05ZAFV30 None    D25E, V31I, M50I, F100Y, L101I, T112V, T125A, K136Q, D167E, V201I, I217V, L234I, V260I, D278A S283G 
FV31 05ZAFV31 None    S17N, S39C, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218L, K219Q, L234I, D278A S283G 
FV5 05ZAFV5 None    K7R, E11D, D25E, F100Q, L101I, K111T, T112V, T124A, T125A, K136Q, D167E, V201I, K215N, L234I, D278A R284G, D286N 
FV6 05ZAFV6 None    D25E, V31I, M50T, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, R269K, D278A S283G, R284G, D286N 
FV7 05ZAFV7 None    D6E, K14R, D25E, V31I, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, A265V, R269K, D278A S283G 
FV8 05ZAFV8 None    K14R, D25E, V31I, K34R, M50T, F100Y, L101I, T112V, T124N, T125A, K136Q, V201I, K211R, T218I, L234I, A265V, D278A S283G 
JF04 05ZAJF04 None    S17N, V31I, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, D278A S283G 
P01 09ZAP01 None   F121L E11D, K14R, D25E, F26Y, V31I, M50I, A91N, L101I, T112V, K136Q, V201I, L234I, R269K, D278A S283G 
P02 09ZAP02 None    E11D, K14R, D25E, F26Y, V31I, V37I, M50I, I60V, F100Y, L101I, T112V, T125A, K136Q, V201I, L234I S283G 
P03 09ZAP03 None    E11D, S24N, D25E, V31I, L101I, T112V, T124N, T125A, I135V, K136H, V165I, V201I, T206S, L234I, A265V, R269K, D278A S283G 
P04 09ZAP04 None    S17N, R20K, D25E, V31I, I72V, I84M, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, N254K, D278A S283G 
P06 09ZAP06 None    D6E, E11D, D25E, V31I, M50I, I84M, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218L, L234I, R269K, D278A S283G 
P07 09ZAP07 None    E11D, S24N, D25E, V31I, M50I, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, K215N, T218I, L234I, R269K, D278A S283G 
P09 09ZAP09 None    D25E, V31I, F100Y, L101I, T112V, T124A, T125A, K136H, F181L, K188R, V201I, T206S, T218L, I220V, L234I, I268L, D278A S283G 
P10 09ZAP10 None    E11D, K14R, S17T, V37I, M50I, I84M, Q95A, E96D, L101I, T112V, T125A, I135V, K136Q, V201I, L234I, S255G, D278A R284G 
P12 09ZAP12 None    R20K, V31I, L45Q, M50I, I60V, F100Y, L101I, T112V, T124A, T125V, D167E, H171Q, K188R, V201I, T218I, L234I, A265V, R269K, D278A S283G 
P13 09ZAP13 None    E11D, K14R, D25E, V31I, L63I, L74I, E96D, L101I, G106A, T112V, T124A, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, R269K, D278A S283G 
P14 09ZAP14 None    S17N, D25E, V31I, M50I, I72V, L74I, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, D278A S283G 
P15 09ZAP15 None    E11D, S24G, D25E, V31I, L101I, K111R, T112V, T124Q, I135V, K136Q, K188R, V201I, L234I, A265V, D278A S283G 
P16 09ZAP16 None    S17N, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, A265V, R269K, D278A S283G 
P18 09ZAP18 None    E11D, A21T, S24N, D25E, M50I, I84M, L101I, G106A, T112M, K136N, V201I, T218I, L234I, A265V, D278A S283G 
P19 09ZAP19 None    D25E, I72V, Y99F, F100Y, L101I, T112V, T124A, T125A, K136T, V201I, T218L, I220V, L234I S283G 
P21 09ZAP21 None    D6E, E10D, D25E, V31I, M50T, I72V, A91G, F100Y, L101I, G106A, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, D278A S283G 
P22 09ZAP22 None    V31I, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, K215N, L234I, A265V, D278A S283G 
P23 09ZAP23 None    E11D, S24N, D25E, V31I, Q95N, L101I, T112V, T124N, K136Q, V201I, L234I, R269K, D278A S283G 
P25 09ZAP25 None    E11D, S24N, D25E, V31I, I84M, F100Y, L101I, T112V, T124A, T125P, K136Q, V201I, K215N, L234I, R269K, D278A S283G 
P26 09ZAP26 None    D6E, S17N, D25E, V31I, L45Q, F100Y, L101I, T112V, T124N, T125A, K136Q, V201I, K215N, T218I, L234V, D278A S283G 
P27 09ZAP27 None    S17T, N18T, D25E, V31I, I84M, L101I, T112I, T124A, T125A, K136Q, V201I, T218I, L234I, R269K, D278A S283G 
P29 09ZAP29 None    E11D, S24N, D25E, V31I, M50I, I60V, L101I, T112V, V201I, T218I, L234I, A265V, R269K S283G, D286N 
P30 09ZAP30 None    S17N, V31I, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, L234I, A265V, R269K, D278A S283G 
P31 09ZAP31 None    K7R, E11D, S24N, D25E, V31I, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, K215N, L234I, A265V, D278A S283D 
P32 09ZAP32 None    K14R, D25E, K34R, L101I, T112V, T124A, T125A, K136Q, G163Q, D167E, V201I, L234I, D278A S283G 
P33 09ZAP33 None    V31I, M50I, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T206S, K215N, Q216K, T218I, K219Q, L234I, R269K, D278A S283G, R284G, D288N 
P34 09ZAP34 None    K14R, D25E, V31I, L101I, T112V, T124N, T125S, K156N, E157Q, G193D, S195C, V201I, L234I, A265V, R269K, D278A S283G 
P35 09ZAP35 None    K14R, S24N, S39C, I60M, I72V, T112V, I113V, T124A, T125A, K136Q, V201I, T206S, T218I, Q221R, L234I S283G 
P36 09ZAP36 None    K14R, D25E, V31I, M50I, L101I, T112V, T124A, T125A, K136Q, D167E, K188R, V201I, K211R, T218I, L234I, A265V, D278A S283G 
P37 09ZAP37 None    S17N, D25E, V31I, I72V, I84M, L101I, T112V, T124A, T125A, K136Q, Q177L, V201I, T218I, L234I, A265V, R269K, D278A S283G 
P38 09ZAP38 None   V54I D6E, K14R, S24N, D25E, L45Q, I72V, I84M, T112V, T124A, T125A, K136Q, V150A, V201I, L234I, D278A S283G 
P39 09ZAP39 None    D25E, I72V, L101I, T112V, T124A, K136Q, V201I, T218I, L234I, D278A S283G 
P40 09ZAP40 None    K14R, V31I, M50T, E96D, F100Y, L101I, G106A, T112V, T124N, T125A, K136Q, Y194C, V201I, T206S, K211N, L234I, A265V, D278A S283G 
P41 09ZAP41 None    R20K, D25E, V31I, M50I, Q95P, F100Y, L101I, T112V, T124N, T125A, K136Q, V201I, T218L, L234I, A265V, R269K, D278A S283G 
P43 09ZAP43 None    K14R, D25E, V31I, M50I, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, L234I, D278A S283G 
P45 09ZAP45 None    D25E, V31I, L101I, T112V, T124A, T125A, K136Q, K156R, V201I, T218I, L234I, A265V, R269K, D278A S283G 
P46 09ZAP46 None    S17N, V31I, M50I, L74I, L101I, K111R, T112V, T125A, K136Q, V201I, K219N, N222K, L234I S283G 
P49 09ZAP49 None    D25E, V31I, I72V, I84M, E96D, L101I, G106A, T112V, T125V, K136Q, V201I, K215Q, L234I, D278A S283G 
P50 09ZAP50 None    D3E, E11D, S17N, D25E, M50T, H51Q, I72T, I84M, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, L234I, D278A S283G 
P51 09ZAP51 None    E11D, D25E, V31I, V37I, M50I, I72V, A91G, L101I, T124A, T125A, K136Q, E157Q, K160Q, D167E, V201I, K211T, L234I, A265V, R269K, D278A R284G, D286N 
P52 09ZAP52 None    S17N, K34R, L101I, T112V, T124A, T125A, G134D, K136T, E157Q, K160Q, D167E, V201I, T206S, L234I, D270E S283G 
P53 09ZAP53 None    S17N, S24D, D25E, P30S, S39C, M50I, T112V, T124N, K136Q, V201I, T206S, L234I, D278A S283G 
P54 09ZAP54 None    D25E, V31I, M50T, I84M, L101I, K111R, T112V, T124N, T125A, V165I, V201I, T206S, L234I, R269K, D278A S283G 
P55 09ZAP55 None    E10D, E11D, S24N, D25E, V31I, L101I, T112M, T125A, K136Q, V201I, L234I, R269K, D278A S283G 
P56 09ZAP56 None    K14R, D25E, V31I, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, Q252P, I257L, R269K, D278A S283G 
P57 09ZAP57 None    S17N, K34R, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, K211R, T218I, K219Q, L234I, Q274K  
P58 09ZAP58 None    K14R, D25E, L28I, P30A, F100Y, L101I, T112V, T124A, T125A, K136N, G193D, V201I, T206S, L234I, K273Q, D278A S283G 
P59 09ZAP59 None    K14R, D25E, V31I, I72V, L101I, T112V, S119P, T124A, T125A, K136Q, V201I, T206S, D207E, Q216R, T218I, K219Q, L234I, R269K, D278A S283G 
P60 09ZAP60 None    S17N, V31I, M50T, F100Y, L101I, T112V, T124G, T125P, K136Q, V201I, T218L, K219Q, L234I, D278A S283G 
P61 09ZAP61 None    D25E, V31I, K34R, F100Y, L101I, T112V, T124N, T125A, K136Q, D167E, V201I, L234I, D278A S283G 
P62 09ZAP62 None    D25E, V31I, M50T, I72V, I84M, A91G, L101I, T112V, T124G, T125A, K136Q, A169G, V201I, L234I, I257L, R269K, D278A K127Q, R231I, S283G, Q285P